Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

Stem Cell Reports

Volumn 6, Issue 4, 2016, Pages 437-446

  Guo, Ge ^a   Von Meyenn, Ferdinand ^b   Santos, Fatima ^b   Chen, Yaoyao ^a   Reik, Wolf ^b,c   Bertone, Paul ^a   Smith, Austin ^a   Nichols, Jennifer ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ASCORBIC ACID; CD172A PROTEIN; DPPA3 PROTEIN; FIBROBLAST GROWTH FACTOR; KRUPPEL LIKE FACTOR 4; MIXL1 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; SMOOTH MUSCLE ACTIN; TFCP2L1 PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANAEROBIC GLYCOLYSIS; ARTICLE; BLASTOCYST; CELL ISOLATION; COLONY FORMATION; COMPARATIVE GENOMIC HYBRIDIZATION; CPG ISLAND; DIPLOIDY; EMBRYO; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INNER CELL MASS; KARYOTYPE; KARYOTYPING; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TETRAPLOIDY; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL PROLIFERATION; CYTOLOGY; DNA METHYLATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENETICS; GERM LAYER; HUMAN EMBRYONIC STEM CELL; METABOLISM; MOUSE; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; BLASTOCYST; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; DNA METHYLATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GERM LAYERS; HUMAN EMBRYONIC STEM CELLS; HUMANS; MICE; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84959297971     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2016.02.005     Document Type: Article

References (40)

1. O. Adewumi, B. Aflatoonian, L. Ahrlund-Richter, M. Amit, P.W. Andrews, G. Beighton, P.A. Bello, N. Benvenisty, L.S. Berry, S. Bevan, and et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative Nat. Biotechnol. 25 2007 803 816
2. P. Blakeley, N.M. Fogarty, I. Del Valle, S.E. Wamaitha, T.X. Hu, K. Elder, P. Snell, L. Christie, P. Robson, and K.K. Niakan Defining the three cell lineages of the human blastocyst by single-cell RNA-seq Development 142 2015 3151 3165
3. T. Boroviak, R. Loos, P. Bertone, A. Smith, and J. Nichols The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification Nat. Cell Biol. 16 2014 516 528
4. T. Boroviak, R. Loos, P. Lombard, J. Okahara, R. Behr, E. Sasaki, J. Nichols, A. Smith, and P. Bertone Lineage-specific profiling delineates the emergence and progression of naive pluripotency in mammalian embryogenesis Dev. Cell 35 2015 366 382
5. I.G. Brons, L.E. Smithers, M.W. Trotter, P. Rugg-Gunn, B. Sun, S.M. Chuva de Sousa Lopes, S.K. Howlett, A. Clarkson, L. Ahrlund-Richter, R.A. Pedersen, and et al. Derivation of pluripotent epiblast stem cells from mammalian embryos Nature 448 2007 191 195
6. F.A. Brook, and R.L. Gardner The origin and efficient derivation of embryonic stem cells in the mouse Proc. Natl. Acad. Sci. USA 94 1997 5709 5712
7. K.C. Davidson, E.A. Mason, and M.F. Pera The pluripotent state in mouse and human Development 142 2015 3090 3099
8. S.J. Dunn, G. Martello, B. Yordanov, S. Emmott, and A.G. Smith Defining an essential transcription factor program for naive pluripotency Science 344 2014 1156 1160
9. D. Dutta, S. Ray, P. Home, M. Larson, M.W. Wolfe, and S. Paul Self-renewal versus lineage commitment of embryonic stem cells: protein kinase C signaling shifts the balance Stem Cells 29 2011 618 628
10. T. Enver, M. Pera, C. Peterson, and P.W. Andrews Stem cell states, fates, and the rules of attraction Cell Stem Cell 4 2009 387 397
11. G. Ficz, T.A. Hore, F. Santos, H.J. Lee, W. Dean, J. Arand, F. Krueger, D. Oxley, Y.L. Paul, J. Walter, and et al. FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency Cell Stem Cell 13 2013 351 359
12. H. Guo, P. Zhu, L. Yan, R. Li, B. Hu, Y. Lian, J. Yan, X. Ren, S. Lin, J. Li, and et al. The DNA methylation landscape of human early embryos Nature 511 2014 606 610
13. E. Habibi, A.B. Brinkman, J. Arand, L.I. Kroeze, H.H. Kerstens, F. Matarese, K. Lepikhov, M. Gut, I. Brun-Heath, N.C. Hubner, and et al. Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells Cell Stem Cell 13 2013 360 369
14. J.A. Hackett, and M.A. Surani Regulatory principles of pluripotency: from the ground state up Cell Stem Cell 15 2014 416 430
15. S.R. Hough, M. Thornton, E. Mason, J.C. Mar, C.A. Wells, and M.F. Pera Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells Stem Cell Rep. 2 2014 881 895
16. K. Huang, T. Maruyama, and G. Fan The naive state of human pluripotent stem cells: a synthesis of stem cell and preimplantation embryo transcriptome analyses Cell Stem Cell 15 2014 410 415
17. P.V. Kharchenko, L. Silberstein, and D.T. Scadden Bayesian approach to single-cell differential expression analysis Nat. Methods 11 2014 740 742
18. H.G. Leitch, K.R. McEwen, A. Turp, V. Encheva, T. Carroll, N. Grabole, W. Mansfield, B. Nashun, J.G. Knezovich, A. Smith, and et al. Naive pluripotency is associated with global DNA hypomethylation Nat. Struct. Mol. Biol. 20 2013 311 316
19. G. Martello, and A. Smith The nature of embryonic stem cells Annu. Rev. Cell Dev. Biol. 30 2014 647 675
20. G. Martello, T. Sugimoto, E. Diamanti, A. Joshi, R. Hannah, S. Ohtsuka, B. Gottgens, H. Niwa, and A. Smith Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal Cell Stem Cell 11 2012 491 504
21. G. Martello, P. Bertone, and A. Smith Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor EMBO J. 32 2013 2561 2574
22. J. Nichols, and A. Smith Naive and primed pluripotent states Cell Stem Cell 4 2009 487 492
23. J. Nichols, J. Silva, M. Roode, and A. Smith Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo Development 136 2009 3215 3222
24. H. Niwa, K. Ogawa, D. Shimosato, and K. Adachi A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells Nature 460 2009 118 122
25. T. O'Leary, B. Heindryckx, S. Lierman, D. van Bruggen, J.J. Goeman, M. Vandewoestyne, D. Deforce, S.M. de Sousa Lopes, and P. De Sutter Tracking the progression of the human inner cell mass during embryonic stem cell derivation Nat. Biotechnol. 30 2012 278 282
26. S.J. Pickering, P.R. Braude, M. Patel, C.J. Burns, J. Trussler, V. Bolton, and S. Minger Preimplantation genetic diagnosis as a novel source of embryos for stem cell research Reprod. Biomed. Online 7 2003 353 364
27. S.J. Pickering, S.L. Minger, M. Patel, H. Taylor, C. Black, C.J. Burns, A. Ekonomou, and P.R. Braude Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis Reprod. Biomed. Online 10 2005 390 397
28. J. Rossant Mouse and human blastocyst-derived stem cells: vive les differences Development 142 2015 9 12
29. Z.D. Smith, M.M. Chan, T.S. Mikkelsen, H. Gu, A. Gnirke, A. Regev, and A. Meissner A unique regulatory phase of DNA methylation in the early mammalian embryo Nature 484 2012 339 344
30. D. Solter, and B.B. Knowles Immunosurgery of mouse blastocyst Proc. Natl. Acad. Sci. USA 72 1975 5099 5102
31. A. Taei, S.-N. Hassani, P. Eftekhari-Yazdi, M. Rezazadeh Valojerdi, M. Nokhbatolfoghahai, N.-S. Masoudi, M. Pakzad, H. Gourabi, and H. Baharvand Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase β and Rho-associated kinase signaling Hum. Reprod. 28 2013 2661 2671
32. Y. Takashima, G. Guo, R. Loos, J. Nichols, G. Ficz, F. Krueger, D. Oxley, F. Santos, J. Clarke, W. Mansfield, and et al. Resetting transcription factor control circuitry toward ground-state pluripotency in human Cell 158 2014 1254 1269
33. P.J. Tesar, J.G. Chenoweth, F.A. Brook, T.J. Davies, E.P. Evans, D.L. Mack, R.L. Gardner, and R.D. McKay New cell lines from mouse epiblast share defining features with human embryonic stem cells Nature 448 2007 196 199
34. T.W. Theunissen, B.E. Powell, H. Wang, M. Mitalipova, D.A. Faddah, J. Reddy, Z.P. Fan, D. Maetzel, K. Ganz, L. Shi, and et al. Systematic identification of culture conditions for induction and maintenance of naive human pluripotency Cell Stem Cell 15 2014 471 487
35. C.W. van den Berg, D.A. Elliott, S.R. Braam, C.L. Mummery, and R.P. Davis Differentiation of human pluripotent stem cells to cardiomyocytes under defined conditions Methods Mol. Biol. 1353 2016 163 180
36. M. Van der Jeught, T. O'Leary, G. Duggal, P. De Sutter, S. Chuva de Sousa Lopes, and B. Heindryckx The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology Hum. Reprod. Update 21 2015 616 626
37. L. Yan, M. Yang, H. Guo, L. Yang, J. Wu, R. Li, P. Liu, Y. Lian, X. Zheng, J. Yan, and et al. Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells Nat. Struct. Mol. Biol. 20 2013 1131 1139
38. S. Ye, P. Li, C. Tong, and Q.L. Ying Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1 EMBO J. 32 2013 2548 2560
39. Q.L. Ying, J. Wray, J. Nichols, L. Batlle-Morera, B. Doble, J. Woodgett, P. Cohen, and A. Smith The ground state of embryonic stem cell self-renewal Nature 453 2008 519 523
40. W. Zhou, M. Choi, D. Margineantu, L. Margaretha, J. Hesson, C. Cavanaugh, C.A. Blau, M.S. Horwitz, D. Hockenbery, C. Ware, and et al. HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition EMBO J. 31 2012 2103 2116