Significance of elevated cobalamin (vitamin B12) levels in blood

Clinical Biochemistry

Volumn 36, Issue 8, 2003, Pages 585-590

  Ermens, A A M ^a   Vlasveld, L T ^b   Lindemans, J ^c  

^a AMPHIA HOSPITAL   (Netherlands)

^b MEDICAL CENTER HAAGLANDEN   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; HAPTOCORRIN;

ACUTE HEPATITIS; BLOOD LEVEL; CELL DAMAGE; CHRONIC MYELOID LEUKEMIA; CYTOLYSIS; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; HUMAN; HYPEREOSINOPHILIC SYNDROME; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DISEASE; LIVER METASTASIS; PATHOLOGY; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REVIEW;

EID: 0242551230     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2003.08.004     Document Type: Review

References (42)

1. Lee G.R., Herbert V.D. Nutritional factors in the production and function of erythrocytes. Lee G.R., Foerster J., Lukens J., Paraskevas F., Greer J.P., Rodgers G.M. Wintrobe's Clinical Hematology. Vol I. 1999;228-267 Williams and Wilkins, Baltimore.
2. Festen H.P.M. Fysiologie en pathofysiologie van de intrinsic factor-secretie en de cobalamine (vitamine B12)-absorptie. Ned Tijdschr Geneesk. 136:1992;1851-1856.
3. Regec A., Quadros E.V., Platica O., Rothenberg S.P. The cloning and characterization of the human transcobalamin II gene. Blood. 85:1995;2711-2719.
4. Gimsing P. Cobalamin metabolism in chronic myelogenous leukemia. Dan Med Bull. 1998;459-479.
5. Burger R.L., Schneider R.J., Mehlman C.S., Allen R.H. Human plasma R-type vitamin B12-binding proteins. II. J Biol Chem. 250:1975;7707-7713.
6. Hall C.A., Begley J.A. Congenital deficiency of human R-type binding proteins of cobalamin. Am J Hum Gen. 29:1977;619-626.
7. Hall C.A. The transport of vitamin B12 from food to use within the cells. J Lab Clin Med. 94:1979;811-816.
8. Lindemans J, Kroes ACM, van GeelJ, Van Kapel J, Schoester M, Abels J. Uptake of transcobalamin II-bound cobalamin by HL-60 cells: effects of differentiation induction. J Exp Cell Res 1989;184:449-60.
9. Soda R., Tavassoli M., Jacobson D.W. Receptor distribution and the endothelial uptake of transcobalamin II in liver cell suspensions. Blood. 65:1985;795-802.
10. Gimsing P. The cobalamin forms and analogues in plasma and myeloid cells during the course of chronic myelogenous leukemia related to the clinical condition. Br J Haematol. 89:1995;812-819.
11. Gimsing P., Petersen C.O., Hippe E. The cobalamin and cobalamin binding proteins in plasma related to the clinical condition in chronic myelogenous leukemia. Leukemia. 9:1995;1604-1609.
12. Omer A., finlayson N.D.C., Shearman D.J.C., Samson R.R., Girdwood R.H. Erythrocyte vitamin B12 activity in health, polycythemia, and in deficiency of vitamin B12 and folate. Blood. 35:1970;73-82.
13. Rachmilewitz B., Manny N., Rachmilewitz M. The transcobalamins in polycythemia vera. Scand J Haematol. 19:1977;453-462.
14. Carmel R. The distribution of endogenous cobalamin among cobalamin-binding proteins in the blood in normal and abnormal states. Am J Clin Nutr. 41:1985;713-719.
15. Zittoun J., Farcet J.P., Marquet J., Sultan C., Zittoun R. Cobalamin vitamin B12 (vitamin B12) and B12 binding proteins in hypereosinophilic syndromes and secondary eosinophilia. Blood. 63:1984;779-783.
16. Rachmilewitz B., Rachmilewitz M., Moshkowitz B., Gross J. Serum transcobala-min in myeloid leukemia. J Lab Clin Med. 78:1971;275-288.
17. Rachmilewitz D., Rachmilewitz E.A., Polliack A., Herchko C.A. Acute promyelocytic leukemia. A report of five cases with a comment on the diagnostic significance of serum vitamin B12 determination. Br J Haematol. 22:1972;87-92.
18. Gilbert H.S., Krauss S., Pasternack B., Herbert V., Wasserman L.R. Serum vitamin B12-binding capacity in myeloproliferative disease. Value in differential diagnosis and as indicators of disease activity. Ann Intern Med. 71:1969;719-729.
19. Zittoun J., Zittoun R., Marquet J., Sultan C. Transcobalamines et lysozyme aux differents stades evolutif de la leucemie myeloide chronique. Nouvelle Revue Francaise d'Hematologie. 15:1975;289-297.
20. Gimsing P., Nexo E. Cobalamin-binding capacity of haptocorrin and transcobalamin Age-correlated reference intervals and values from patients. Clin Chem. 35:1989;1447-1451.
21. Areekul S., Panatampon P., Doungbarn J. Vitamin B12 and vitamin B12 binding proteins in liver disease. Southeast Asian J Trop Med Pub Hlth. 8:1977;322-328.
22. Hagelskjaer L., Rasmussen K. Methylmalonic acid concentration in serum not affected in hepatic disease. Clin Chem. 38:1992;493-495.
23. Kanazawa S., Herbert V. Total corrinoid, cobalamin and cobalamin analogue levels may be normal in serum despite cobalamin in liver depletion in patients with alcoholism. Lab Invest. 53:1985;108-110.
24. Baker H., Leevy C.B., DeAngelis B., Frank O., Baker E.R. Cobalamin and holotranscobalamin changes in plasma and liver tissue in alcoholics with liver disease. J Am Coll Nutr. 17:1998;235-238.
25. Djalali M., Champigneulle B., Gueant J.L., Kholty S., Gerard P., Nicolas J.P. Increased serum corrinoids correlates with disease severity and IgA levels in alcoholic cirrhosis. Digestion. 41:1988;215-222.
26. Lindemans J., Abels J., Neijens H.J., Kerrebijn K.F. Elevated vitamin B12 in cystic fibrosis. Acta Paediatr Scand. 73:1984;768-771.
27. Osifo B.O.A., Ayoola A., Parmentier Y., Gerard P., Nicolas J.P. Correlation between serum enzymes and serum unsaturated vitamin B12 binding proteins in primary liver carcinoma. Enzyme. 9:1988;161-166.
28. Fremont S., Chamigneulle B., Gerard P., Felden P., Lambert D., Gueant J.L., Nicolas J.P. Blood transcobalamin levels in malignant hepatoma. Tumor Biol. 12:1991;353-359.
29. Kane S.P., Murray-Lyon I.M., Paradinas F.J., et al. Vitamin B12 binding protein as a tumour marker for hepatocellular carcinoma. Gut. 19:1978;1105-1109.
30. Wheeler K., Pritchard J., Luck W., Rossiter M. Transcobalamin I as a marker for fibrolamellar hepatoma. Med Ped Oncol. 14:1986;227-229.
31. Gimsing P., Hippe E. Increased concentration of transcobalamin I in a patient with metastatic carcinoma of the breast. Scand J Haematol. 21:1978;243-249.
32. Carmel R. Extreme elevation of serum transcobalamin I in a patient with metastatic cancer. NEJM. 292:1975;282-284.
33. Carmel R., Eisenberg L. Serum vitamin B12 and transcobalamin abnormalities in patients with cancer. Cancer. 40:1977;1348-1353.
34. Wakatsuki Y., Inada M., Kudo H., Oshio G., Masudo T., Miyake T., Kita T. Immunological characterization and clinical implication of cobalamin binding protein in human gastric cancer. Cancer Res. 49:1989;3122-3128.
35. Jensen H.S., gimsing P., Pedersen F., Hippe E. Transcobalamin II as an indicator of activity in metastatic renal carcinoma. Cancer. 52:1983;1700-1704.
36. Carmel R., Tatsis B., Baril L. Circulating antibody to transcobalamin II causing retention of vitamin B12 in the blood. Blood. 49:1977;987-1000.
37. Reynolds E.H., Bottiglieri T., Laundy M., et al. Subacute combined degeneration with high serum vitamin B12 level and abnormal vitamin B12 binding protein. Arch Neurol. 50:1993;739-742.
38. Bolann B.J., Solli J.D., Schneede J., et al. Elevation of indicators of cobalamin deficiency defined as cobalamin-induced reduction in increased serum methylmalonic acid. Clin Chem. 46:2000;1744-1750.
39. Stabler S.P., Allen R.H., Savage D.G., Lindenbaum J. Clinical spectrum and diagnosis of cobalamin deficiency. Blood. 76:1990;871-888.
40. Lambert D., Benhayoun S., Adjalla C., et al. Alcoholic cirrhosis and cobalamin metabolism. Digestion. 58:1997;64-71.
41. Lensen C.J.P.A., Vlasveld L.T., Ermens A.A.M. Reduction of hyperhomocysteinemia in a patient with CML treated with hydroxycarbamid. Neth J Med. 54:1999;A10.
42. Nexo E., Olesen H., Norredam K., Schwartz M. A rare case of megaloblastic anaemia caused by disturbances in the plasma cobalamin binding proteins in a patient with hepatocellular carcinoma. Scand J Haemtol. 1975;320-327.