Crude Saponins of Panax notoginseng Have Neuroprotective Effects to Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine Differentiated RGC-5 Retinal Ganglion Cells

Journal of Agricultural and Food Chemistry

Volumn 64, Issue 7, 2016, Pages 1528-1539

  Wang, Dan Dan ^a   Zhu, Hua Zhang ^a   Li, Shi Wei ^a   Yang, Jia Ming ^a   Xiao, Yang ^a   Kang, Qiang Rong ^a   Li, Chen Yang ^a   Zhao, Yun Shi ^a   Zeng, Yong ^b   Li, Yan ^b   Zhang, Jian ^a   He, Zhen Dan ^a   Ying, Ying ^a  

^a Shenzhen University School of Medicine   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; CSPN; differentiated RGC 5 cells; ER stress; palmitate; PSD 95; ROS

Indexed keywords

CELL DEATH; CELL MEMBRANES; CELLS; CYTOLOGY; EYE PROTECTION; MEDICINE; METABOLITES; OPHTHALMOLOGY; PROTEINS;

CSPN; ENDOPLASMIC RETICULUM STRESS; ER STRESS; NEUROPROTECTIVE EFFECTS; PALMITATE; PSD-95; REACTIVE OXYGEN SPECIES; TRADITIONAL CHINESE MEDICINE;

PALMITIC ACID;

HERBACEOUS AGENT; NERVE PROTEIN; NEUROPROTECTIVE AGENT; PALMITIC ACID DERIVATIVE; SAPAP PROTEINS; SAPONIN; STAUROSPORINE;

APOPTOSIS; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; GENETICS; HUMAN; METABOLISM; OXIDATIVE STRESS; PANAX NOTOGINSENG; RETINA GANGLION CELL;

APOPTOSIS; CELL DIFFERENTIATION; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM STRESS; HUMANS; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PALMITATES; PANAX NOTOGINSENG; RETINAL GANGLION CELLS; SAPONINS; STAUROSPORINE;

EID: 84959237714     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b05864     Document Type: Article

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