Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes in Vivo Attenuates Liver Fibrosis

Cell Stem Cell

Volumn 18, Issue 6, 2016, Pages 797-808

  Song, Guangqi ^a   Pacher, Martin ^a,b   Balakrishnan, Asha ^a,b   Yuan, Qinggong ^a,b   Tsay, Hsin Chieh ^a,b   Yang, Dakai ^a   Reetz, Julia ^c   Brandes, Sabine ^a,b   Dai, Zhen ^a   Pützer, Brigitte M ^c   Araúzo Bravo, Marcos J ^d,e   Steinemann, Doris ^a   Luedde, Tom ^f   Schwabe, Robert F ^g   Manns, Michael P ^a   Schöler, Hans R ^h   Schambach, Axel ^a   Cantz, Tobias ^a   Ott, Michael ^a,b   Sharma, Amar Deep ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^c ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

^d BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^e BASQUE FOUNDATION FOR SCIENCE   (Spain)

^f UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^g Och Spine at New York Presbyterian Hospitals   (United States)

^h MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LENTIVIRUS VECTOR; NEUROTROPHIN RECEPTOR P75; TRANSCRIPTION FACTOR GATA 4; 1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; BIOLOGICAL MARKER; CRE RECOMBINASE; INTEGRASE; TRANSCRIPTION FACTOR;

ADENOVIRIDAE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL FATE; CONTROLLED STUDY; DOWN REGULATION; ECTOPIC EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; STELLATE CELL; ANIMAL; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; CELL LINEAGE; CHOLESTASIS; COMPLICATION; CYTOLOGY; DEPENDOPARVOVIRUS; DNA MICROARRAY; LIVER; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; BIOMARKERS; CELL LINEAGE; CELLULAR REPROGRAMMING; CHOLESTASIS; DEPENDOVIRUS; DICARBETHOXYDIHYDROCOLLIDINE; HEPATOCYTES; INTEGRASES; LIVER; LIVER CIRRHOSIS; MICE, INBRED BALB C; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MYOFIBROBLASTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION FACTORS;

EID: 84959149568     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.01.010     Document Type: Article

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