Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Lu, Cheng ^a,b   Liao, Guojian ^c   Zhang, Jihui ^a   Tan, Huarong ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SOUTHWEST UNIVERSITY   (China)

Author keywords

Bioassay; Nikkomycin; Streptomyces ansochromogenes; Tylosin analogues; wblA

Indexed keywords

BACTERIAL RNA; NIKKOMYCIN; TYLOSIN DERIVATIVE; 23-O-MYCINOSYLTYLACTONE; 6-HYDROXY-21-O-MYCINOSYLTYLACTONE; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; GLYCOSIDE; TYLOSIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; BACILLUS SUBTILIS; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL SPORE; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; FERMENTATION; GRAM POSITIVE BACTERIUM; HOMOLOGOUS RECOMBINATION; MASS SPECTROMETRY; METABOLITE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; STREPTOMYCES; STREPTOMYCES ANSOCHROMOGENES; WBLA GENE; WILD TYPE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMISTRY; CONFORMATION; DISK DIFFUSION; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MUTATION; PHENOTYPE;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DISK DIFFUSION ANTIMICROBIAL TESTS; GLYCOSIDES; GRAM-POSITIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR CONFORMATION; MUTATION; PHENOTYPE; STREPTOCOCCUS PNEUMONIAE; STREPTOMYCES; TYLOSIN;

EID: 84959115322     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0359-5     Document Type: Article

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