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Volumn 13, Issue 1, 2014, Pages

Novel nikkomycin analogues generated by mutasynthesis in Streptomyces ansochromogenes

Author keywords

Mutasynthesis; Novel analogues; sanL mutant; Streptomyces ansochromogenes

Indexed keywords

4 HYDROXYBENZOIC ACID; BENZOIC ACID; ISONICOTINIC ACID; NICOTINIC ACID; NIKKOMYCIN; NIKKOMYCIN PX; NIKKOMYCIN PZ; NIKKOMYCIN X; NIKKOMYCIN Z; PICOLINIC ACID; UNCLASSIFIED DRUG;

EID: 84899653514     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-13-59     Document Type: Article
Times cited : (28)

References (23)
  • 1
    • 0033756147 scopus 로고    scopus 로고
    • A gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes
    • 10.1007/s002840010141, 11014866, Cloning, sequencing, and function of sanF
    • Chen W, Zeng H, Tan H,. Cloning, sequencing, and function of sanF A gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Curr Microbiol 2000, 41:312-316. 10.1007/s002840010141, 11014866, Cloning, sequencing, and function of sanF.
    • (2000) Curr Microbiol , vol.41 , pp. 312-316
    • Chen, W.1    Zeng, H.2    Tan, H.3
  • 2
    • 0018459489 scopus 로고
    • Metabolic products of microorganisms. 181. Chitin synthase from fungi, a test model for substances with insecticidal properties
    • 10.1007/BF00409207, 380491
    • Brillinger GU. Metabolic products of microorganisms. 181. Chitin synthase from fungi, a test model for substances with insecticidal properties. Arch Microbiol 1979, 121:71-74. 10.1007/BF00409207, 380491.
    • (1979) Arch Microbiol , vol.121 , pp. 71-74
    • Brillinger, G.U.1
  • 3
    • 0017078545 scopus 로고
    • Stoffwechselprodukte von mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer hemmstoff der chitinsynthese bei pilzen
    • 10.1007/BF00446834, 1259515
    • Dahn U, Hagenmaier H, Hohne H, Konig WA, Wolf G, Zahner H. Stoffwechselprodukte von mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer hemmstoff der chitinsynthese bei pilzen. Arch Microbiol 1976, 107:143-160. 10.1007/BF00446834, 1259515.
    • (1976) Arch Microbiol , vol.107 , pp. 143-160
    • Dahn, U.1    Hagenmaier, H.2    Hohne, H.3    Konig, W.A.4    Wolf, G.5    Zahner, H.6
  • 4
    • 33646118511 scopus 로고    scopus 로고
    • SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes
    • 10.1016/j.ymben.2005.12.002, 16464627
    • Niu G, Liu G, Tian Y, Tan H. SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes. Metab Eng 2006, 8:183-195. 10.1016/j.ymben.2005.12.002, 16464627.
    • (2006) Metab Eng , vol.8 , pp. 183-195
    • Niu, G.1    Liu, G.2    Tian, Y.3    Tan, H.4
  • 5
    • 15944401749 scopus 로고    scopus 로고
    • A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development
    • 10.1111/j.1365-2958.2005.04512.x, 15752205
    • Liu G, Tian Y, Yang H, Tan H. A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development. Mol Microbiol 2005, 55:1855-1866. 10.1111/j.1365-2958.2005.04512.x, 15752205.
    • (2005) Mol Microbiol , vol.55 , pp. 1855-1866
    • Liu, G.1    Tian, Y.2    Yang, H.3    Tan, H.4
  • 6
    • 65349122992 scopus 로고    scopus 로고
    • The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes
    • 10.1111/j.1365-2958.2009.06681.x, 19400773
    • Pan Y, Liu G, Yang H, Tian Y, Tan H. The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes. Mol Microbiol 2009, 72:710-723. 10.1111/j.1365-2958.2009.06681.x, 19400773.
    • (2009) Mol Microbiol , vol.72 , pp. 710-723
    • Pan, Y.1    Liu, G.2    Yang, H.3    Tian, Y.4    Tan, H.5
  • 7
    • 0036008124 scopus 로고    scopus 로고
    • Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics
    • 10.1016/S1074-5521(02)00090-X, 11841943
    • Chen H, Hubbard BK, O'Connor SE, Walsh CT. Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics. Chem Biol 2002, 9:103-112. 10.1016/S1074-5521(02)00090-X, 11841943.
    • (2002) Chem Biol , vol.9 , pp. 103-112
    • Chen, H.1    Hubbard, B.K.2    O'Connor, S.E.3    Walsh, C.T.4
  • 8
    • 80255141922 scopus 로고    scopus 로고
    • Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis
    • 10.1111/j.1742-4658.2011.08319.x, 21884568
    • Binter A, Oberdorfer G, Hofzumahaus S, Nerstheimer S, Altenbacher G, Gruber K, Macheroux P. Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis. FEBS J 2011, 278:4122-4135. 10.1111/j.1742-4658.2011.08319.x, 21884568.
    • (2011) FEBS J , vol.278 , pp. 4122-4135
    • Binter, A.1    Oberdorfer, G.2    Hofzumahaus, S.3    Nerstheimer, S.4    Altenbacher, G.5    Gruber, K.6    Macheroux, P.7
  • 9
    • 0032081277 scopus 로고    scopus 로고
    • The Streptomyces tendae Tü901 L-lysine 2-aminotransferase catalyzes the initial reaction in nikkomycin D biosynthesis
    • 10.1046/j.1432-1327.1998.2540347.x, 9660190
    • Bruntner C, Bormann C. The Streptomyces tendae Tü901 L-lysine 2-aminotransferase catalyzes the initial reaction in nikkomycin D biosynthesis. Eur J Biochem 1998, 254:347-355. 10.1046/j.1432-1327.1998.2540347.x, 9660190.
    • (1998) Eur J Biochem , vol.254 , pp. 347-355
    • Bruntner, C.1    Bormann, C.2
  • 10
    • 3142779218 scopus 로고    scopus 로고
    • Nikkomycin biosynthesis: formation of a 4-electron oxidation product during turnover of NikD with its physiological substrate
    • 10.1021/bi0493618, 15248773
    • Bruckner RC, Zhao G, Venci D, Jorns MS. Nikkomycin biosynthesis: formation of a 4-electron oxidation product during turnover of NikD with its physiological substrate. Biochemistry 2004, 43:9160-9167. 10.1021/bi0493618, 15248773.
    • (2004) Biochemistry , vol.43 , pp. 9160-9167
    • Bruckner, R.C.1    Zhao, G.2    Venci, D.3    Jorns, M.S.4
  • 11
    • 18844408121 scopus 로고    scopus 로고
    • Improvement of nikkomycin production by enhanced copy of sanU and sanV in Streptomyces ansochromogenes and characterization of a novel glutamate mutase encoded by sanU and sanV
    • 10.1016/j.ymben.2005.01.002, 15885615
    • Li Y, Ling H, Li W, Tan H. Improvement of nikkomycin production by enhanced copy of sanU and sanV in Streptomyces ansochromogenes and characterization of a novel glutamate mutase encoded by sanU and sanV. Metab Eng 2005, 7:165-173. 10.1016/j.ymben.2005.01.002, 15885615.
    • (2005) Metab Eng , vol.7 , pp. 165-173
    • Li, Y.1    Ling, H.2    Li, W.3    Tan, H.4
  • 12
    • 84879989844 scopus 로고    scopus 로고
    • Biosynthesis and regulation of secondary metabolites in microorganisms
    • 10.1007/s11427-013-4501-5, 23832246
    • Niu G, Tan H. Biosynthesis and regulation of secondary metabolites in microorganisms. Sci China Life Sci 2013, 56:581-583. 10.1007/s11427-013-4501-5, 23832246.
    • (2013) Sci China Life Sci , vol.56 , pp. 581-583
    • Niu, G.1    Tan, H.2
  • 13
    • 70349560014 scopus 로고    scopus 로고
    • New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis
    • 10.1002/cbic.200900246, 19554593
    • Eichner S, Floss HG, Sasse F, Kirschning A. New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis. Chembiochem 2009, 10:1801-1805. 10.1002/cbic.200900246, 19554593.
    • (2009) Chembiochem , vol.10 , pp. 1801-1805
    • Eichner, S.1    Floss, H.G.2    Sasse, F.3    Kirschning, A.4
  • 15
    • 0344791676 scopus 로고    scopus 로고
    • Production of nikkomycins Bx and Bz by mutasynthesis with genetically engineered Streptomyces tendae Tü901
    • 10.7164/antibiotics.52.102, 10344563
    • Bormann C, Kalmanczhelyi A, Sussmuth R, Jung G. Production of nikkomycins Bx and Bz by mutasynthesis with genetically engineered Streptomyces tendae Tü901. J Antibiot (Tokyo) 1999, 52:102-108. 10.7164/antibiotics.52.102, 10344563.
    • (1999) J Antibiot (Tokyo) , vol.52 , pp. 102-108
    • Bormann, C.1    Kalmanczhelyi, A.2    Sussmuth, R.3    Jung, G.4
  • 16
    • 76849092076 scopus 로고    scopus 로고
    • Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production
    • 10.1186/1475-2859-9-6, 2817672, 20096125
    • Liao G, Li J, Li L, Yang H, Tian Y, Tan H. Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production. Microb Cell Fact 2010, 9:6. 10.1186/1475-2859-9-6, 2817672, 20096125.
    • (2010) Microb Cell Fact , vol.9 , pp. 6
    • Liao, G.1    Li, J.2    Li, L.3    Yang, H.4    Tian, Y.5    Tan, H.6
  • 17
    • 35449001091 scopus 로고    scopus 로고
    • Identification and characterization of sanH and sanI involved in the hydroxylation of pyridyl residue during nikkomycin biosynthesis in Streptomyces ansochromogenes
    • 10.1007/s00284-007-9028-1, 17899263
    • Xie Z, Niu G, Li R, Liu G, Tan H. Identification and characterization of sanH and sanI involved in the hydroxylation of pyridyl residue during nikkomycin biosynthesis in Streptomyces ansochromogenes. Curr Microbiol 2007, 55:537-542. 10.1007/s00284-007-9028-1, 17899263.
    • (2007) Curr Microbiol , vol.55 , pp. 537-542
    • Xie, Z.1    Niu, G.2    Li, R.3    Liu, G.4    Tan, H.5
  • 18
    • 0032816588 scopus 로고    scopus 로고
    • Novel nikkomycins Lx and Lz produced by genetically engineered Streptomyces tendae Tü901
    • 10.7164/antibiotics.52.582, 10470685
    • Bormann C, Lauer B, Kalmanczhelyi A, Sussmuth R, Jung G. Novel nikkomycins Lx and Lz produced by genetically engineered Streptomyces tendae Tü901. J Antibiot (Tokyo) 1999, 52:582-585. 10.7164/antibiotics.52.582, 10470685.
    • (1999) J Antibiot (Tokyo) , vol.52 , pp. 582-585
    • Bormann, C.1    Lauer, B.2    Kalmanczhelyi, A.3    Sussmuth, R.4    Jung, G.5
  • 19
    • 0026575735 scopus 로고
    • Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector
    • 10.1016/0378-1119(92)90603-M, 1547955
    • MacNeil DJ, Gewain KM, Ruby CL, Dezeny G, Gibbons PH, MacNeil T. Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. Gene 1992, 111:61-68. 10.1016/0378-1119(92)90603-M, 1547955.
    • (1992) Gene , vol.111 , pp. 61-68
    • MacNeil, D.J.1    Gewain, K.M.2    Ruby, C.L.3    Dezeny, G.4    Gibbons, P.H.5    MacNeil, T.6
  • 20
    • 0036716276 scopus 로고    scopus 로고
    • Cloning and function of sanQ: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes
    • 10.1007/s00284-001-0115-4, 12177738
    • Zeng H, Tan H, Li J. Cloning and function of sanQ: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Curr Microbiol 2002, 45:175-179. 10.1007/s00284-001-0115-4, 12177738.
    • (2002) Curr Microbiol , vol.45 , pp. 175-179
    • Zeng, H.1    Tan, H.2    Li, J.3
  • 22
    • 0021768599 scopus 로고
    • Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector
    • Fiedler HP. Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector. J Chromatogr 1984, 316:487-494.
    • (1984) J Chromatogr , vol.316 , pp. 487-494
    • Fiedler, H.P.1
  • 23
    • 84867036786 scopus 로고    scopus 로고
    • Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes
    • 10.1186/1475-2859-11-135, 3520715, 23043373
    • Li J, Li L, Feng C, Chen Y, Tan H. Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes. Microb Cell Fact 2012, 11:135. 10.1186/1475-2859-11-135, 3520715, 23043373.
    • (2012) Microb Cell Fact , vol.11 , pp. 135
    • Li, J.1    Li, L.2    Feng, C.3    Chen, Y.4    Tan, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.