Cloning and function of sanQ: A gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes

Current Microbiology

Volumn 45, Issue 3, 2002, Pages 175-179

  Zeng, Hongmei ^a,b   Tan, Huarong ^a   Li, Jilun ^b  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DNA FRAGMENT; KANAMYCIN; NIKKOMYCIN; NIKKOMYCIN X; NIKKOMYCIN Z; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN;

ANTIBIOTIC BIOSYNTHESIS; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; COSMID; DNA LIBRARY; DNA PROBE; GENE DISRUPTION; GENE FUNCTION; GENE IDENTIFICATION; GENE INACTIVATION; GENE INSERTION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SANQ GENE; SEQUENCE ANALYSIS; SEQUENCE DATABASE; SEQUENCE HOMOLOGY; STREPTOMYCES; STREPTOMYCES ANSOCHROMOGENES; WILD TYPE; AMINO ACID SEQUENCE; BIOSYNTHESIS; CHROMOSOME MAP; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); INSERTION SEQUENCES; PROKARYOTA; STREPTOMYCES; STREPTOMYCES ANSOCHROMOGENES; UNCULTURED ACTINOMYCETE;

AMINO ACID SEQUENCE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CHROMOSOME MAPPING; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES;

EID: 0036716276     PISSN: 03438651     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00284-001-0115-4     Document Type: Article

References (16)

1. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
2. Betlach MC, Kealey JT, Betlach MC, Ashley GW, McDaniel R (1998) Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin. Biochemistry 37:14937-14942
3. z by mutasynthesis with genetically engineered Streptomyces tendae Tü901. J Antibiot (Tokyo) 52:102-108
4. Bormann C, Mattern S, Schrempf H, Fiedler H-P, Zähner H (1989) Isolation of Streptomyces tendae mutants with an altered nikkomycin spectrum. J Antibiot (Tokyo) 42:913-918
5. Bruntner C, Bormann C (1998) The Streptomyces tendae Tü901 L-lysine 2-aminotransferase catalyzes the initial reaction in nikkomycin D biosynthesis. Eur J Biochem 254:347-355
6. Bruntner C, Lauer B, Schwarz W, Möhrle V, Bormann C (1999) Molecular characterization of co-transcribed genes from Streptomyces tendae Tü901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin. Mol Gen Genet 262:102-114
7. Chen W, Zeng H, Tan H (2000) Cloning, sequencing and function of sanF: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Curr Microbiol 41:312-316
8. Dähn U, Hagenmaier H, Höhne H, König WA, Wolf G, Zähner H (1976) Stoffwechselprodukte von Mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer Hemmstoff der Chitinsynthese bei Pilzen. Arch Microbiol 107:143-160
9. Fiedler HP (1984) Screening for new microbial products by high performance liquid chromatography using a photodiode array detector. J Chromatogr 316:487-494
10. Ishikawa J, Hotta K (1999) FramePlot: a new implementation of the Frame analysis for predicting protein-coding regions in bacterial DNA with a high G+C content. FEMS Microbiol Lett 174:251-253
11. Jia J, Li W, Chen W, Nie L, Tan H (2000) Cloning, sequencing and function of sanA, a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Sci China (Series C) 43:30-38
12. Kieser T, Bibb MJ, Buttner MJ, Chater KF, Hopwood DA (2000) Practical Streptomyces genetics. Norwich: The John Innes Foundation
13. Li W, Jia J, Tan H, Hu Y, Wang Z (2000) Cloning, sequencing and function of sanB, a gene related to nikkomycin biosynthesis of Streptomyces ansochromogenes. Chin Sci Bull 45:2158-2162
14. MacNeil DJ, Gewain KM, Ruby CL, Dezeny G, Gibbons PH, MacNeil T (1992) Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. Gene 111:61-68
15. Roos U, Mattern S, Schrempf H, Bormann C (1992) Histidine aminotransferase activity in Streptomyces tendae and its correlation with nikkomycin production. FEMS Microbiol Lett 97:185-190
16. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press