β-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function

Phytomedicine

Volumn 23, Issue 3, 2016, Pages 316-323

  Teng, Yu Ning ^a   Sheu, Ming Jyh ^a   Hsieh, Yow Wen ^a,b   Wang, Ruey Yun ^a   Chiang, Yao Chang ^a   Hung, Chin Chuan ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Multidrug resistant cancer; P gp; Reversal effects; carotene

Indexed keywords

ABC TRANSPORTER; BETA CAROTENE; BREAST CANCER RESISTANCE PROTEIN; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; VERAPAMIL; VINBLASTINE; VINCRISTINE; ABCB1 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; TUMOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG TRANSPORT; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROPHILICITY; IC50; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; STABLE EXPRESSION; UTERINE CERVIX CARCINOMA; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; DRUG RESISTANCE; METABOLISM; MULTIDRUG RESISTANCE; NEOPLASM; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATASES; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BETA CAROTENE; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NEOPLASMS; P-GLYCOPROTEINS; VERAPAMIL;

EID: 84959082252     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2016.01.008     Document Type: Article

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