YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity

Nature Communications

Volumn 7, Issue , 2016, Pages

  Hwang, Soo Seok ^a,b,c   Jang, Sung Woong ^a   Kim, Min Kyung ^a   Kim, Lark Kyun ^b,c   Kim, Bong Sung ^d   Kim, Hyeong Su ^a   Kim, Kiwan ^a   Lee, Wonyong ^a   Flavell, Richard A ^b,c   Lee, Gap Ryol ^a  

^a Sogang University   (South Korea)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR YY1; TRANSFORMING GROWTH FACTOR BETA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; PROTEIN BINDING; YY1 PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; GENE EXPRESSION; GENETIC DIFFERENTIATION; HOMEOSTASIS; IMMUNE SYSTEM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EXPERIMENTAL COLITIS; GENE EXPRESSION; GENE LOCUS; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; COLITIS; CYTOLOGY; FEMALE; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; COLITIS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; T-LYMPHOCYTES, REGULATORY; YY1 TRANSCRIPTION FACTOR;

EID: 84959019257     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10789     Document Type: Article

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