메뉴 건너뛰기




Volumn 22, Issue 3, 2016, Pages 670-679

Targeting Cancer Stem Cells in Castration-Resistant Prostate Cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; CD24 ANTIGEN; DOCETAXEL; HERMES ANTIGEN; IWP 2; LKG 974; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN DAB2IP; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DAB2IP PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN BINDING; TAXOID;

EID: 84959018543     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-15-0190     Document Type: Article
Times cited : (73)

References (50)
  • 1
    • 33846239456 scopus 로고    scopus 로고
    • Beyond tumorigenesis: Cancer stem cells in metastasis
    • Li F, Tiede B,Massague J, Kang Y. Beyond tumorigenesis: Cancer stem cells in metastasis. Cell Res 2007;17:3-14.
    • (2007) Cell Res , vol.17 , pp. 3-14
    • Li, F.1    Tiede, B.2    Massague, J.3    Kang, Y.4
  • 2
    • 84860642507 scopus 로고    scopus 로고
    • The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration
    • Qin J, Liu X, Laffin B, Chen X, ChoyG, Jeter CR, et al. The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell 2012;10:556-69.
    • (2012) Cell Stem Cell , vol.10 , pp. 556-569
    • Qin, J.1    Liu, X.2    Laffin, B.3    Chen, X.4    Choy, G.5    Jeter, C.R.6
  • 4
    • 39449090031 scopus 로고    scopus 로고
    • CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
    • Hurt EM, Kawasaki BT, Klarmann GJ, Thomas SB, Farrar WL. CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Br J Cancer 2008;98:756-65.
    • (2008) Br J Cancer , vol.98 , pp. 756-765
    • Hurt, E.M.1    Kawasaki, B.T.2    Klarmann, G.J.3    Thomas, S.B.4    Farrar, W.L.5
  • 5
    • 44749091840 scopus 로고    scopus 로고
    • Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
    • Naor D, Wallach-Dayan SB, Zahalka MA, Sionov RV. Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 2008;18:260-7.
    • (2008) Semin Cancer Biol , vol.18 , pp. 260-267
    • Naor, D.1    Wallach-Dayan, S.B.2    Zahalka, M.A.3    Sionov, R.V.4
  • 7
    • 33645167402 scopus 로고    scopus 로고
    • A novel antiapoptotic mechanism based on interference of Fas signaling by CD44 variant isoforms
    • Mielgo A, Van Driel M, Bloem A, Landmann L, Gunthert U. A novel antiapoptotic mechanism based on interference of Fas signaling by CD44 variant isoforms. Cell Death Differ 2006;13:465-77.
    • (2006) Cell Death Differ , vol.13 , pp. 465-477
    • Mielgo, A.1    Van Driel, M.2    Bloem, A.3    Landmann, L.4    Gunthert, U.5
  • 8
    • 4143149778 scopus 로고    scopus 로고
    • CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bonemarrow endothelial cells
    • Draffin JE,McFarlane S, Hill A, Johnston PG, Waugh DJ. CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bonemarrow endothelial cells. Cancer Res 2004;64:5702-11.
    • (2004) Cancer Res , vol.64 , pp. 5702-5711
    • Draffin, J.E.1    McFarlane, S.2    Hill, A.3    Johnston, P.G.4    Waugh, D.J.5
  • 10
    • 84906251455 scopus 로고    scopus 로고
    • The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth
    • Tsai YS, Lai CL, Lai CH, Chang KH, Wu K, Tseng SF, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget 2014;5:6425-36.
    • (2014) Oncotarget , vol.5 , pp. 6425-6436
    • Tsai, Y.S.1    Lai, C.L.2    Lai, C.H.3    Chang, K.H.4    Wu, K.5    Tseng, S.F.6
  • 11
    • 77249104533 scopus 로고    scopus 로고
    • Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
    • Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, et al. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A 2010;107:2485-90.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2485-2490
    • Xie, D.1    Gore, C.2    Liu, J.3    Pong, R.C.4    Mason, R.5    Hao, G.6
  • 12
    • 84930275766 scopus 로고    scopus 로고
    • DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1
    • Yun EJ, Baek ST, Xie D, Tseng SF, Dobin T, Hernandez E, et al. DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1. Oncogene 2015;34:2741-52.
    • (2015) Oncogene , vol.34 , pp. 2741-2752
    • Yun, E.J.1    Baek, S.T.2    Xie, D.3    Tseng, S.F.4    Dobin, T.5    Hernandez, E.6
  • 13
    • 79952366631 scopus 로고    scopus 로고
    • Evidence of epithelial to mesenchymal transition associated with increased tumorigenic potential in an immortalized normal prostate epithelial cell line
    • Marian CO, Yang L, Zou YS, Gore C, Pong RC, Shay JW, et al. Evidence of epithelial to mesenchymal transition associated with increased tumorigenic potential in an immortalized normal prostate epithelial cell line. Prostate 2011;71:626-36.
    • (2011) Prostate , vol.71 , pp. 626-636
    • Marian, C.O.1    Yang, L.2    Zou, Y.S.3    Gore, C.4    Pong, R.C.5    Shay, J.W.6
  • 14
    • 0028104888 scopus 로고
    • Lipofectionmediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA
    • Weijerman PC, Konig JJ, Wong ST, Niesters HG, Peehl DM. Lipofectionmediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA. Cancer Res 1994;54:5579-83.
    • (1994) Cancer Res , vol.54 , pp. 5579-5583
    • Weijerman, P.C.1    Konig, J.J.2    Wong, S.T.3    Niesters, H.G.4    Peehl, D.M.5
  • 15
    • 84855350566 scopus 로고    scopus 로고
    • Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells
    • Xu D, Lin TH, Li S, Da J,Wen XQ, Ding J, et al. Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells. Cancer lett 2012;316:11-22.
    • (2012) Cancer Lett , vol.316 , pp. 11-22
    • Xu, D.1    Lin, T.H.2    Li, S.3    Da Jwen, X.Q.4    Ding, J.5
  • 17
    • 0036154828 scopus 로고    scopus 로고
    • The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
    • Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M, et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 2002;8:22-8.
    • (2002) Clin Cancer Res , vol.8 , pp. 22-28
    • Kim, M.1    Turnquist, H.2    Jackson, J.3    Sgagias, M.4    Yan, Y.5    Gong, M.6
  • 18
    • 9744254768 scopus 로고    scopus 로고
    • Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses
    • Zhao L, Wientjes MG, Au JL. Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses. Clin Cancer Res 2004;10:7994-8004.
    • (2004) Clin Cancer Res , vol.10 , pp. 7994-8004
    • Zhao, L.1    Wientjes, M.G.2    Au, J.L.3
  • 19
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999;17:1474-81.
    • (1999) J Clin Oncol , vol.17 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 20
    • 77957902732 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition ismechanistically linked with stem cell signatures in prostate cancer cells
    • Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, et al. Epithelial to mesenchymal transition ismechanistically linked with stem cell signatures in prostate cancer cells. PLoS One 2010;5:e12445.
    • (2010) PLoS One , vol.5 , pp. e12445
    • Kong, D.1    Banerjee, S.2    Ahmad, A.3    Li, Y.4    Wang, Z.5    Sethi, S.6
  • 21
    • 0030472709 scopus 로고    scopus 로고
    • Immortalized and tumorigenic adult human prostatic epithelial cell lines: Characteristics and applications. Part I. Cell markers and immortalized nontumorigenic cell lines
    • Webber MM, Bello D, Quader S. Immortalized and tumorigenic adult human prostatic epithelial cell lines: Characteristics and applications. Part I. Cell markers and immortalized nontumorigenic cell lines. Prostate 1996; 29:386-94.
    • (1996) Prostate , vol.29 , pp. 386-394
    • Webber, M.M.1    Bello, D.2    Quader, S.3
  • 22
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996;183:1797-806.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 24
    • 84877057303 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance in cancer stem cells
    • Abdullah LN, Chow EK. Mechanisms of chemoresistance in cancer stem cells. Clin Transl Med 2013;2:3.
    • (2013) Clin Transl Med , vol.2 , pp. 3
    • Abdullah, L.N.1    Chow, E.K.2
  • 25
    • 46149089421 scopus 로고    scopus 로고
    • Growthinhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression
    • Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, et al. Growthinhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 2008;134:62-73.
    • (2008) Cell , vol.134 , pp. 62-73
    • Godar, S.1    Ince, T.A.2    Bell, G.W.3    Feldser, D.4    Donaher, J.L.5    Bergh, J.6
  • 26
    • 84871858375 scopus 로고    scopus 로고
    • Overcoming docetaxel resistance in prostate cancer: A perspective review
    • Hwang C. Overcoming docetaxel resistance in prostate cancer: A perspective review. Ther Adv Med Oncol 2012;4:329-40.
    • (2012) Ther Adv Med Oncol , vol.4 , pp. 329-340
    • Hwang, C.1
  • 27
    • 33745971037 scopus 로고    scopus 로고
    • Carcinoma of the prostate: Overview of the most common malignancy in men
    • Carson CC, 3rd. Carcinoma of the prostate: Overview of the most common malignancy in men. North Carolina Med J 2006;67:122-7.
    • (2006) North Carolina Med J , vol.67 , pp. 122-127
    • Carson, C.C.1
  • 28
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • ClarkeMF, Dick JE,Dirks PB, Eaves CJ, Jamieson CH, JonesDL, et al. Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 2006;66:9339-44.
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.5    Jones, D.L.6
  • 29
    • 34247111243 scopus 로고    scopus 로고
    • International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate: A meta-analysis of 1446 patients
    • Shaw GL, Wilson P, Cuzick J, Prowse DM, Goldenberg SL, Spry NA, et al. International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate: A meta-analysis of 1446 patients. BJU Int 2007;99:1056-65.
    • (2007) BJU Int , vol.99 , pp. 1056-1065
    • Shaw, G.L.1    Wilson, P.2    Cuzick, J.3    Prowse, D.M.4    Goldenberg, S.L.5    Spry, N.A.6
  • 30
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005;5:275-84.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 31
    • 77749297990 scopus 로고    scopus 로고
    • An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB
    • Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med 2010; 16:286-94.
    • (2010) Nat Med , vol.16 , pp. 286-294
    • Min, J.1    Zaslavsky, A.2    Fedele, G.3    McLaughlin, S.K.4    Reczek, E.E.5    De Raedt, T.6
  • 32
    • 0028242956 scopus 로고
    • CD44 in differentiated embryonic stem cells: Surface expression and transcripts encoding multiple variants
    • Haegel H, Dierich A, Ceredig R. CD44 in differentiated embryonic stem cells: Surface expression and transcripts encoding multiple variants. Dev Immunol 1994;3:239-46.
    • (1994) Dev Immunol , vol.3 , pp. 239-246
    • Haegel, H.1    Dierich, A.2    Ceredig, R.3
  • 33
    • 33645026803 scopus 로고    scopus 로고
    • Highly purifiedCD44+prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
    • Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, Tang S, et al. Highly purifiedCD44+prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 2006;25:1696-708.
    • (2006) Oncogene , vol.25 , pp. 1696-1708
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Li, H.4    Bhatia, B.5    Tang, S.6
  • 34
    • 79953042645 scopus 로고    scopus 로고
    • CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule?
    • Zoller M. CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule? Nat Rev Cancer 2011;11:254-67.
    • (2011) Nat Rev Cancer , vol.11 , pp. 254-267
    • Zoller, M.1
  • 35
    • 0027065573 scopus 로고
    • Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
    • Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci U S A 1992;89: 12160-4.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 12160-12164
    • Screaton, G.R.1    Bell, M.V.2    Jackson, D.G.3    Cornelis, F.B.4    Gerth, U.5    Bell, J.I.6
  • 36
    • 2642671976 scopus 로고    scopus 로고
    • A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia
    • Legras S, Gunthert U, Stauder R, Curt F, Oliferenko S, Kluin-Nelemans HC, et al. A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia. Blood 1998;91:3401-13.
    • (1998) Blood , vol.91 , pp. 3401-3413
    • Legras, S.1    Gunthert, U.2    Stauder, R.3    Curt, F.4    Oliferenko, S.5    Kluin-Nelemans, H.C.6
  • 37
    • 0025825209 scopus 로고
    • A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
    • Gunthert U, Hofmann M, Rudy W, Reber S, Zoller M, Haussmann I, et al. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991;65:13-24.
    • (1991) Cell , vol.65 , pp. 13-24
    • Gunthert, U.1    Hofmann, M.2    Rudy, W.3    Reber, S.4    Zoller, M.5    Haussmann, I.6
  • 38
    • 84897020336 scopus 로고    scopus 로고
    • CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance
    • Ni J, Cozzi PJ, Hao JL, Beretov J, Chang L, Duan W, et al. CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance. Prostate 2014;74:602-17.
    • (2014) Prostate , vol.74 , pp. 602-617
    • Ni, J.1    Cozzi, P.J.2    Hao, J.L.3    Beretov, J.4    Chang, L.5    Duan, W.6
  • 39
    • 0346422159 scopus 로고    scopus 로고
    • Decreased levels of CD44 protein and mRNA in prostate carcinoma Correlation with tumor grade and ploidy
    • Kallakury BV, Yang F, Figge J, Smith KE, Kausik SJ, Tacy NJ, et al. Decreased levels of CD44 protein and mRNA in prostate carcinoma. Correlation with tumor grade and ploidy. Cancer 1996;78:1461-9.
    • (1996) Cancer , vol.78 , pp. 1461-1469
    • Kallakury, B.V.1    Yang, F.2    Figge, J.3    Smith, K.E.4    Kausik, S.J.5    Tacy, N.J.6
  • 41
    • 0031981414 scopus 로고    scopus 로고
    • CD44 and CD44v6 downregulation in clinical prostatic carcinoma: Relation to Gleason grade and cytoarchitecture
    • De Marzo AM, Bradshaw C, Sauvageot J, Epstein JI, Miller GJ. CD44 and CD44v6 downregulation in clinical prostatic carcinoma: Relation to Gleason grade and cytoarchitecture. Prostate 1998;34:162-8.
    • (1998) Prostate , vol.34 , pp. 162-168
    • De Marzo, A.M.1    Bradshaw, C.2    Sauvageot, J.3    Epstein, J.I.4    Miller, G.J.5
  • 42
    • 0029971763 scopus 로고    scopus 로고
    • Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes
    • Maltzman JS, Carman JA, Monroe JG. Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes. Mol Cell Biol 1996;16:2283-94.
    • (1996) Mol Cell Biol , vol.16 , pp. 2283-2294
    • Maltzman, J.S.1    Carman, J.A.2    Monroe, J.G.3
  • 43
    • 0033950160 scopus 로고    scopus 로고
    • Role of activating protein-1 and high mobility group-I(Y) protein in the induction of CD44 gene expression by interleukin-1beta in vascular smooth muscle cells
    • Foster LC, Wiesel P,Huggins GS, Panares R, Chin MT, Pellacani A, et al. Role of activating protein-1 and high mobility group-I(Y) protein in the induction of CD44 gene expression by interleukin-1beta in vascular smooth muscle cells. FASEB J 2000;14:368-78.
    • (2000) FASEB J , vol.14 , pp. 368-378
    • Foster, L.C.1    Wiesel Phuggins, G.S.2    Panares, R.3    Chin, M.T.4    Pellacani, A.5
  • 44
    • 84871846692 scopus 로고    scopus 로고
    • WNT signalling pathways as therapeutic targets in cancer
    • Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013;13:11-26.
    • (2013) Nat Rev Cancer , vol.13 , pp. 11-26
    • Anastas, J.N.1    Moon, R.T.2
  • 45
    • 45549109525 scopus 로고    scopus 로고
    • Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis
    • Zeilstra J, Joosten SP, DokterM, Verwiel E, Spaargaren M, Pals ST. Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis. Cancer Res 2008;68:3655-61.
    • (2008) Cancer Res , vol.68 , pp. 3655-3661
    • Zeilstra, J.1    Joosten, S.P.2    Dokter, M.3    Verwiel, E.4    Spaargaren, M.5    Pals, S.T.6
  • 46
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 48
    • 84896495041 scopus 로고    scopus 로고
    • Prostate cancer bone metastases acquire resistance to androgen deprivation via WNT5A-mediated BMP-6 induction
    • LeeGT, Kang DI, Ha YS, Jung YS, Chung J, Min K, et al. Prostate cancer bone metastases acquire resistance to androgen deprivation via WNT5A-mediated BMP-6 induction. Br J Cancer 2014;110:1634-44.
    • (2014) Br J Cancer , vol.110 , pp. 1634-1644
    • Lee, G.T.1    Kang, D.I.2    Ha, Y.S.3    Jung, Y.S.4    Chung, J.5    Min, K.6
  • 49
    • 34249679271 scopus 로고    scopus 로고
    • ABC transporters and drug resistance in leukemia: Was P-gpnothing but the first head of theHydra?
    • Steinbach D, Legrand O. ABC transporters and drug resistance in leukemia: Was P-gpnothing but the first head of theHydra? Leukemia 2007;21:1172-6.
    • (2007) Leukemia , vol.21 , pp. 1172-1176
    • Steinbach, D.1    Legrand, O.2
  • 50
    • 84875752240 scopus 로고    scopus 로고
    • Emerging targeted agents in metastatic breast cancer
    • Zardavas D, Baselga J, Piccart M. Emerging targeted agents in metastatic breast cancer. Nat Rev Clin Oncol 2013;10:191-210.
    • (2013) Nat Rev Clin Oncol , vol.10 , pp. 191-210
    • Zardavas, D.1    Baselga, J.2    Piccart, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.