Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300

ACS Medicinal Chemistry Letters

Volumn 7, Issue 2, 2016, Pages 151-155

  Shrimp, Jonathan H ^a   Sorum, Alexander W ^a   Garlick, Julie M ^a   Guasch, Laura ^a   Nicklaus, Marc C ^a   Meier, Jordan L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Acetylation; acetyltransferase; epigenetics; PAINS; pan assay interference; probes; reversible covalent inhibitor

Indexed keywords

C 646; ELECTROPHILE; ENZYME INHIBITOR; THIOL; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; DERIVATIZATION; DRUG TARGETING; EPIGENETICS; FOLLOW UP; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN POLYMERIZATION; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84958949800     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00385     Document Type: Article

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