-
1
-
-
84923762812
-
A new initiative on precision medicine
-
Collins F.S., & Varmus H. A new initiative on precision medicine. N. Engl. J. Med. 372, 793-795 (2015
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 793-795
-
-
Collins, F.S.1
Varmus, H.2
-
2
-
-
84923062584
-
Patients in context-EHR capture of social, and behavioral determinants of health
-
Adler N.E., & Stead W.W. Patients in context-EHR capture of social, and behavioral determinants of health. N. Engl. J. Med. 372, 698-701 (2015
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 698-701
-
-
Adler, N.E.1
Stead, W.W.2
-
3
-
-
84880059657
-
The electronic medical records, and genomics (emerge) Network: Past, present, and future
-
Gottesman O., et al. The Electronic Medical Records, and Genomics (eMERGE). Network: past, present, and future. Genet. Med. 15, 761-771 (2013
-
(2013)
Genet. Med
, vol.15
, pp. 761-771
-
-
Gottesman, O.1
-
4
-
-
84958893899
-
Million Veteran Program: A mega-biobank to study genetic influences on health, and disease
-
e-pub ahead of print
-
Gaziano J.M., et al. Million Veteran Program: A mega-biobank to study genetic influences on health, and disease. J. Clin. Epidemiol. (2015); e-pub ahead of print
-
(2015)
J. Clin. Epidemiol
-
-
Gaziano, J.M.1
-
5
-
-
84939422197
-
Characterizing race/ethnicity, and genetic ancestry for 100,000 subjects in the genetic epidemiology research on adult health, and aging (gera
-
Banda Y., et al. Characterizing race/ethnicity, and genetic ancestry for 100,000 subjects in the Genetic Epidemiology Research on Adult Health, and Aging (GERA). Cohort. Genetics 200, 1285-1295 (2015
-
(2015)
Cohort. Genetics
, vol.200
, pp. 1285-1295
-
-
Banda, Y.1
-
6
-
-
84896386442
-
UK Biobank Data come, and get it
-
224ed4
-
Allen N.E., Sudlow C., Peakman T., Collins R., & Biobank O.B.O.U. UK Biobank Data: come, and get it. Sci. Transl. Med. 6, 224ed4 (2014
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Allen, N.E.1
Sudlow, C.2
Peakman, T.3
Collins, R.4
Biobank, O.B.O.U.5
-
7
-
-
0034659688
-
The Icelandic Healthcare Database, and informed consent
-
Gulcher J.R., & Stefansson K. The Icelandic Healthcare Database, and informed consent. N. Engl. J. Med. 342, 1827-1830 (2000
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 1827-1830
-
-
Gulcher, J.R.1
Stefansson, K.2
-
8
-
-
84899788364
-
Biobanks, and electronic medical records: Enabling cost-effective research
-
234cm3
-
Bowton E., et al. Biobanks, and electronic medical records: enabling cost-effective research. Sci. Transl. Med. 6, 234cm3 (2014
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Bowton, E.1
-
9
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases, and 3,000 shared controls
-
The Wellcome Trust Case Control C
-
The Wellcome Trust Case Control C. Genome-wide association study of 14,000 cases of seven common diseases, and 3,000 shared controls. Nature 447, 661-678 (2007
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
10
-
-
80053896220
-
Variants near foxe1 are associated with hypothyroidism, and other thyroid conditions: Using electronic medical records for genome-and phenome-wide studies
-
Denny J.C., et al. Variants near FOXE1 are associated with hypothyroidism, and other thyroid conditions: using electronic medical records for genome-and phenome-wide studies. Am. J. Hum. Genet. 89, 529-542 (2011
-
(2011)
Am. J. Hum. Genet
, vol.89
, pp. 529-542
-
-
Denny, J.C.1
-
11
-
-
84958914304
-
Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance
-
e-pub ahead of print
-
Wei W.Q., Teixeira P.L., Mo H., Cronin R.M., Warner J.L., & Denny J.C. Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance. J. Am. Med. Inform. Assoc. (2015); e-pub ahead of print
-
(2015)
J. Am. Med. Inform. Assoc
-
-
Wei, W.Q.1
Teixeira, P.L.2
Mo, H.3
Cronin, R.M.4
Warner, J.L.5
Denny, J.C.6
-
12
-
-
84928601920
-
Extracting research-quality phenotypes from electronic health records to support precision medicine
-
Wei W.Q., & Denny J.C. Extracting research-quality phenotypes from electronic health records to support precision medicine. Genome Med. 7, 41 (2015
-
(2015)
Genome Med
, vol.7
, Issue.41
-
-
Wei, W.Q.1
Denny, J.C.2
-
13
-
-
77950338000
-
Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record
-
Ritchie M.D., et al. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. Am. J. Hum. Genet. 86, 560-572 (2010
-
(2010)
Am. J. Hum. Genet
, vol.86
, pp. 560-572
-
-
Ritchie, M.D.1
-
14
-
-
84986887437
-
Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record
-
Lin C., et al. Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record. J. Am. Med. Inform. Assoc. 22, e151-e161 (2015
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. e151-e161
-
-
Lin, C.1
-
15
-
-
84863554305
-
Portability of an algorithm to identify rheumatoid arthritis in electronic health records
-
Carroll R.J., et al. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. J. Am. Med. Inform. Assoc. 19, e162-e169 (2012
-
(2012)
J. Am. Med. Inform. Assoc
, vol.19
, pp. e162-e169
-
-
Carroll, R.J.1
-
16
-
-
84857146745
-
Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study
-
Kho A.N., et al. Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. J. Am. Med. Inform. Assoc. 19, 212-218 (2011
-
(2011)
J. Am. Med. Inform. Assoc
, vol.19
, pp. 212-218
-
-
Kho, A.N.1
-
17
-
-
84954203288
-
Desiderata for computable representations of electronic health records-driven phenotype algorithms
-
Mo H., et al. Desiderata for computable representations of electronic health records-driven phenotype algorithms. J. Am. Med. Inform. Assoc. 22, 1220-1230 (2015
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. 1220-1230
-
-
Mo, H.1
-
18
-
-
34748833432
-
Integration of clinical, and genetic data in the i2b2 architecture
-
Murphy S.N., Mendis M.E., Berkowitz D.A., Kohane I., & Chueh H.C. Integration of clinical, and genetic data in the i2b2 architecture. AMIA Annu. Symp. Proc., 1040 (2006
-
(2006)
AMIA Annu. Symp. Proc
, vol.1040
-
-
Murphy, S.N.1
Mendis, M.E.2
Berkowitz, D.A.3
Kohane, I.4
Chueh, H.C.5
-
19
-
-
84883213248
-
Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: An electronic medical record-based genome-wide association study
-
Ding K., et al. Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. G3 (Bethesda, MD). 3, 1061-1068 (2013
-
(2013)
G3 (Bethesda, MD)
, vol.3
, pp. 1061-1068
-
-
Ding, K.1
-
20
-
-
84921539950
-
Genetic variation in the HLA region is associated with susceptibility to herpes zoster
-
Crosslin D.R., et al. Genetic variation in the HLA region is associated with susceptibility to herpes zoster. Genes Immun. 16, 1-7 (2015
-
(2015)
Genes Immun
, vol.16
, pp. 1-7
-
-
Crosslin, D.R.1
-
21
-
-
84891858260
-
A genome-and phenome-wide association study to identify genetic variants influencing platelet count, and volume, and their pleiotropic effects
-
Shameer K., et al. A genome-and phenome-wide association study to identify genetic variants influencing platelet count, and volume, and their pleiotropic effects. Hum. Genet. 133, 95-109 (2014
-
(2014)
Hum. Genet
, vol.133
, pp. 95-109
-
-
Shameer, K.1
-
22
-
-
77958522275
-
A genomewide association study of red blood cell traits using the electronic medical record
-
Kullo I.J., Ding K., Jouni H., Smith C.Y., & Chute C.G. A genomewide association study of red blood cell traits using the electronic medical record. PLoS One 5, (2010
-
(2010)
Plos One
, vol.5
-
-
Kullo, I.J.1
Ding, K.2
Jouni, H.3
Smith, C.Y.4
Chute, C.G.5
-
23
-
-
84855958154
-
Predicting clopidogrel response using DNA samples linked to an electronic health record
-
Delaney J.T., et al. Predicting clopidogrel response using DNA samples linked to an electronic health record. Clin. Pharmacol. Ther. 91, 257-263 (2012
-
(2012)
Clin. Pharmacol. Ther
, vol.91
, pp. 257-263
-
-
Delaney, J.T.1
-
24
-
-
84863229218
-
Predicting warfarin dosages in European-American, and African-American subjects using DNA samples linked to an electronic health record
-
e-pub ahead of print
-
Ramirez A.H., et al. Predicting warfarin dosages in European-American, and African-American subjects using DNA samples linked to an electronic health record. Pharmagenomics (2012); e-pub ahead of print
-
(2012)
Pharmagenomics
-
-
Ramirez, A.H.1
-
25
-
-
83655184675
-
The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients
-
Birdwell K.A., et al. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenet. Genomics 22, 32-42 (2012
-
(2012)
Pharmacogenet. Genomics
, vol.22
, pp. 32-42
-
-
Birdwell, K.A.1
-
26
-
-
67349174180
-
Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy
-
Onitilo A.A., et al. Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy. Breast Cancer Res. Treat. 115, 643-650 (2009
-
(2009)
Breast Cancer Res. Treat
, vol.115
, pp. 643-650
-
-
Onitilo, A.A.1
-
27
-
-
67349174180
-
Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy
-
Onitilo A.A., et al. Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy. Breast Cancer Res. Treat. 115, 643-650 (2009
-
(2009)
Breast Cancer Res. Treat
, vol.115
, pp. 643-650
-
-
Onitilo, A.A.1
-
28
-
-
84928656687
-
A genome-wide association study of heparininduced thrombocytopenia using an electronic medical record
-
Karnes J.H., et al. A genome-wide association study of heparininduced thrombocytopenia using an electronic medical record. Thrombosis Haemostasis 113, 772-681 (2015
-
(2015)
Thrombosis Haemostasis
, vol.113
, pp. 772-781
-
-
Karnes, J.H.1
-
29
-
-
84931262058
-
Genome-wide association study of serum creatinine levels during vancomycin therapy
-
Van Driest S.L., et al. Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy. PLoS One 10, e0127791 (2015
-
(2015)
Plos One
, vol.10
, pp. e0127791
-
-
Van Driest, S.L.1
-
30
-
-
84984608981
-
Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia
-
Karol S.E., et al. Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Blood 126, 1770-1776 (2015
-
(2015)
Blood
, vol.126
, pp. 1770-1776
-
-
Karol, S.E.1
-
31
-
-
84948379555
-
Genomewide-association identifies a novel locus for anthracycline cardiotoxicity
-
Wells Q.S., et al. Genomewide-association identifies a novel locus for anthracycline cardiotoxicity. Circulation 128, A15509 (2013
-
(2013)
Circulation
, vol.128
, pp. A15509
-
-
Wells, Q.S.1
-
32
-
-
84919819892
-
Genotype, and risk of major bleeding during warfarin treatment
-
Kawai V.K., et al. Genotype, and risk of major bleeding during warfarin treatment. Pharmacogenomics 15, 1973-1983 (2014
-
(2014)
Pharmacogenomics
, vol.15
, pp. 1973-1983
-
-
Kawai, V.K.1
-
33
-
-
84901234705
-
Genetic risk factors for major bleeding in warfarin patients in a community setting
-
Roth J.A., et al. Genetic risk factors for major bleeding in warfarin patients in a community setting. Clin. Pharmacol. Ther. 95, 636-643 (2014
-
(2014)
Clin. Pharmacol. Ther
, vol.95
, pp. 636-643
-
-
Roth, J.A.1
-
34
-
-
84889824971
-
A pharmacogenetic versus a clinical algorithm for warfarin dosing
-
Kimmel S.E., et al. A pharmacogenetic versus a clinical algorithm for warfarin dosing. N. Engl. J. Med. 369, 2283-2293 (2013
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 2283-2293
-
-
Kimmel, S.E.1
-
35
-
-
84889873119
-
A randomized trial of genotype-guided dosing of warfarin
-
Pirmohamed M., et al. A randomized trial of genotype-guided dosing of warfarin. N. Engl. J. Med. 369, 2294-2303 (2013
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 2294-2303
-
-
Pirmohamed, M.1
-
36
-
-
84894501950
-
Warfarin pharmacogenetics: An illustration of the importance of studies in minority populations
-
Perera M.A., Cavallari L.H., & Johnson J.A. Warfarin pharmacogenetics: an illustration of the importance of studies in minority populations. Clin. Pharmacol. Ther. 95, 242-244 (2014
-
(2014)
Clin. Pharmacol. Ther
, vol.95
, pp. 242-244
-
-
Perera, M.A.1
Cavallari, L.H.2
Johnson, J.A.3
-
37
-
-
84883135237
-
Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study
-
Perera M.A., et al. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet 382, 790-796 (2013
-
(2013)
Lancet
, vol.382
, pp. 790-796
-
-
Perera, M.A.1
-
38
-
-
84938095470
-
Race influences warfarin dose changes associated with genetic factors
-
Limdi N.A., et al. Race influences warfarin dose changes associated with genetic factors. Blood 126, 539-545 (2015
-
(2015)
Blood
, vol.126
, pp. 539-545
-
-
Limdi, N.A.1
-
39
-
-
84875931887
-
Genome-and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk
-
Ritchie M.D., et al. Genome-and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation 127, 1377-1385 (2013
-
(2013)
Circulation
, vol.127
, pp. 1377-1385
-
-
Ritchie, M.D.1
-
40
-
-
77952822074
-
Phewas: Demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
-
Denny J.C., et al. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics 26, 1205-1210 (2010
-
(2010)
Bioinformatics
, vol.26
, pp. 1205-1210
-
-
Denny, J.C.1
-
41
-
-
84890107642
-
Systematic comparison of phenome-wide association study of electronic medical record data, and genome-wide association study data
-
Denny J.C., et al. Systematic comparison of phenome-wide association study of electronic medical record data, and genome-wide association study data. Nat. Biotechnol. 31, 1102-1111 (2013
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 1102-1111
-
-
Denny, J.C.1
-
42
-
-
84876907114
-
A phewas approach in studying HLA-drb1∗1501
-
Hebbring S.J., Schrodi S.J., Ye Z., Zhou Z., Page D., & Brilliant M.H. A PheWAS approach in studying HLA-DRB1∗1501. Genes Immun. 14, 187-191 (2013
-
(2013)
Genes Immun
, vol.14
, pp. 187-191
-
-
Hebbring, S.J.1
Schrodi, S.J.2
Ye, Z.3
Zhou, Z.4
Page, D.5
Brilliant, M.H.6
-
43
-
-
84926659527
-
Opportunities for drug repositioning from phenome-wide association studies
-
Rastegar-Mojarad M., Ye Z., Kolesar J.M., Hebbring S.J., & Lin S.M. Opportunities for drug repositioning from phenome-wide association studies. Nat. Biotechnol. 33, 342-345 (2015
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 342-345
-
-
Rastegar-Mojarad, M.1
Ye, Z.2
Kolesar, J.M.3
Hebbring, S.J.4
Lin, S.M.5
-
44
-
-
84919624872
-
Detection of pleiotropy through a phenome-wide association study (phewas) of epidemiologic data as part of the environmental architecture for genes linked to environment (eagle) study
-
Hall M.A., et al. Detection of pleiotropy through a phenome-wide association study (PheWAS). of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE). study. PLoS Genet. 10, e1004678 (2014
-
(2014)
Plos Genet
, vol.10
, pp. e1004678
-
-
Hall, M.A.1
-
45
-
-
85000443086
-
Partitioning heritability by functional annotation using genome-wide association summary statistics
-
Finucane H.K., et al. Partitioning heritability by functional annotation using genome-wide association summary statistics. Nat. Genet. 47, 1228-1235 (2015
-
(2015)
Nat. Genet
, vol.47
, pp. 1228-1235
-
-
Finucane, H.K.1
-
46
-
-
84946040296
-
Identification of type 2 diabetes subgroups through topological analysis of patient similarity
-
311ra174-311ra174
-
Li L., et al. Identification of type 2 diabetes subgroups through topological analysis of patient similarity. Sci. Transl. Med. 7, 311ra174-311ra174 (2015
-
(2015)
Sci. Transl. Med
, vol.7
-
-
Li, L.1
-
47
-
-
85027911145
-
Validating drug repurposing signals using electronic health records: A case study of metformin associated with reduced cancer mortality
-
e-pub ahead of print
-
Xu H., et al. Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality. J. Am. Med. Inform. Assoc. (2014); e-pub ahead of print
-
(2014)
J. Am. Med. Inform. Assoc
-
-
Xu, H.1
-
48
-
-
84894288992
-
Genetics of rheumatoid arthritis contributes to biology, and drug discovery
-
Okada Y., et al. Genetics of rheumatoid arthritis contributes to biology, and drug discovery. Nature 506, 376-381 (2014
-
(2014)
Nature
, vol.506
, pp. 376-381
-
-
Okada, Y.1
-
49
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen J.C., Boerwinkle E., Mosley T.H., Jr., & Hobbs H.H. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N. Engl. J. Med. 354, 1264-1272 (2006
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley, T.H.3
Hobbs, H.H.4
-
50
-
-
84941997939
-
PCSK9 inhibition in patients with hypercholesterolemia
-
Desai N.R., & Sabatine M.S. PCSK9 inhibition in patients with hypercholesterolemia. Trends Cardiovasc. Med. 25, 567-574 (2015
-
(2015)
Trends Cardiovasc. Med
, vol.25
, pp. 567-574
-
-
Desai, N.R.1
Sabatine, M.S.2
-
51
-
-
84915819121
-
Inactivating mutations in NPC1L1, and protection from coronary heart disease
-
Stitziel N.O., et al. Inactivating mutations in NPC1L1, and protection from coronary heart disease. N. Engl. J. Med. 371, 2072-2082 (2014
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 2072-2082
-
-
Stitziel, N.O.1
-
52
-
-
70349627428
-
Opportunities, and challenges for the nih-an interview with francis collins interview by robert steinbrook
-
Collins F. Opportunities, and challenges for the NIH-an interview with Francis Collins. Interview by Robert Steinbrook. N. Engl. J. Med. 361, 1321-1323 (2009
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1321-1323
-
-
Collins, F.1
-
53
-
-
84880727398
-
The pharmacogenomics research network translational pharmacogenetics program: Overcoming challenges of real-world implementation
-
Shuldiner A.R., et al. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clin. Pharmacol. Ther. 94, 207-210 (2013
-
(2013)
Clin. Pharmacol. Ther
, vol.94
, pp. 207-210
-
-
Shuldiner, A.R.1
-
54
-
-
84875939245
-
Implementing genomic medicine in the clinic: The future is here
-
Manolio T.A., et al. Implementing genomic medicine in the clinic: the future is here. Genet. Med. 15, 258-267 (2013
-
(2013)
Genet. Med
, vol.15
, pp. 258-267
-
-
Manolio, T.A.1
-
55
-
-
84902553307
-
Impact of point-of-care testing for cyp2c19 on platelet inhibition in patients with acute coronary syndrome, and early dual antiplatelet therapy in the emergency setting
-
Stimpfle F., et al. Impact of point-of-care testing for CYP2C19 on platelet inhibition in patients with acute coronary syndrome, and early dual antiplatelet therapy in the emergency setting. Thromb. Res. 134, 105-110 (2014
-
(2014)
Thromb. Res
, vol.134
, pp. 105-110
-
-
Stimpfle, F.1
-
56
-
-
84896316037
-
Clinical pharmacogenetics implementation: Approaches successes, and challenges
-
Weitzel K.W., et al. Clinical pharmacogenetics implementation: approaches, successes, and challenges. Am. J. Med. Genet. C Semin. Med. Genet. 166C, 56-67 (2014
-
(2014)
Am. J. Med. Genet. C Semin. Med. Genet
, vol.166
, pp. 56-67
-
-
Weitzel, K.W.1
-
57
-
-
84862620703
-
Operational implementation of prospective genotyping for personalized medicine: The design of the vanderbilt predict project
-
Pulley J.M., et al. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT Project. Clin. Pharmacol. Ther. 92, 87-95 (2012
-
(2012)
Clin. Pharmacol. Ther
, vol.92
, pp. 87-95
-
-
Pulley, J.M.1
-
58
-
-
84893549013
-
Development, and use of active clinical decision support for preemptive pharmacogenomics
-
Bell G.C., et al. Development, and use of active clinical decision support for preemptive pharmacogenomics. J. Am. Med. Inform. Assoc. 21, e93-99 (2014
-
(2014)
J. Am. Med. Inform. Assoc
, vol.21
, pp. e93-99
-
-
Bell, G.C.1
-
59
-
-
84864118842
-
Optimizing drug outcomes through pharmacogenetics: A case for preemptive genotyping
-
Schildcrout J.S., et al. Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping. Clin. Pharmacol. Ther. 92, 235-2342 (2012
-
(2012)
Clin. Pharmacol. Ther
, vol.92
, pp. 235-2342
-
-
Schildcrout, J.S.1
-
60
-
-
84896637856
-
Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing
-
Van Driest S.L., et al. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. Clin. Pharmacol. Ther. 95, 423-431 (2014
-
(2014)
Clin. Pharmacol. Ther
, vol.95
, pp. 423-431
-
-
Van Driest, S.L.1
-
61
-
-
79951809825
-
Cpic: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
-
Relling M.V., & Klein T.E. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin. Pharmacol. Ther. 89, 464-467 (2011
-
(2011)
Clin. Pharmacol. Ther
, vol.89
, pp. 464-467
-
-
Relling, M.V.1
Klein, T.E.2
-
62
-
-
33749339075
-
Cytochrome p450 2c19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
-
Hulot J.S., et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 108, 2244-2247 (2006
-
(2006)
Blood
, vol.108
, pp. 2244-2247
-
-
Hulot, J.S.1
-
63
-
-
78049326068
-
Reduced-function CYP2C19 genotype, and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
-
Mega J.L., et al. Reduced-function CYP2C19 genotype, and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 304, 1821-1830 (2010
-
(2010)
JAMA
, vol.304
, pp. 1821-1830
-
-
Mega, J.L.1
-
64
-
-
84984884423
-
Abstract 11802: Clinical implementation of cyp2c19-genotype guided antiplatelet therapy reduces cardiovascular events after pci
-
Cavallari L.H., et al. Abstract 11802: clinical implementation of CYP2C19-genotype guided antiplatelet therapy reduces cardiovascular events after PCI. Circulation 132, A11802 (2015
-
(2015)
Circulation
, vol.132
, pp. A11802
-
-
Cavallari, L.H.1
-
65
-
-
38949196447
-
HLA-B∗5701 screening for hypersensitivity to abacavir
-
Mallal S., et al. HLA-B∗5701 screening for hypersensitivity to abacavir. N. Engl. J. Med. 358, 568-579 (2008
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 568-579
-
-
Mallal, S.1
-
66
-
-
84930526399
-
Clin gen-the clinical genome resource
-
Rehm H.L., et al. ClinGen-the clinical genome resource. N. Engl. J. Med. 372, 2235-2242 (2015
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 2235-2242
-
-
Rehm, H.L.1
-
67
-
-
84952717626
-
Penetrance of hemochromatosis in HFE genotypes resulting in p.Cys282Tyr, and p.[Cys282Tyr]; [His63Asp] in the emerge Network
-
Gallego, Carlos J., et al. Penetrance of hemochromatosis in HFE genotypes resulting in p.Cys282Tyr, and p.[Cys282Tyr]; [His63Asp] in the eMERGE Network. Am. J. Hum. Genet. 97, 512-520 (2015
-
(2015)
Am. J. Hum. Genet
, vol.97
, pp. 512-520
-
-
Gallego Carlos, J.1
-
68
-
-
85031968398
-
Rare potentially pathogenic variants in the congenital arrhythmia syndrome disease genes SCN5A, and KCNH2 are detected frequently but rarely associated with arrhythmia phenotypes in electronic health records. Accepted for presentation
-
Van Driest S., et al. Rare potentially pathogenic variants in the congenital arrhythmia syndrome disease genes SCN5A, and KCNH2 are detected frequently but rarely associated with arrhythmia phenotypes in electronic health records. Accepted for presentation, Am. Soc. Hum. Genet. 2014 Scientific Sessions (2014
-
(2014)
Am. Soc. Hum. Genet. 2014 Scientific Sessions
-
-
Van Driest, S.1
-
69
-
-
84958859712
-
-
Accessed 23 November 2015
-
https://www.nih.gov/sites/default/files/research-training/initiatives/pmi/pmi-working-group-report-20150917-2.pdf (2015). Accessed 23 November, 2015
-
(2015)
-
-
-
70
-
-
84894504519
-
Characterization of statin dose response in electronic medical records
-
Wei W.Q., et al. Characterization of statin dose response in electronic medical records. Clin. Pharmacol. Ther. 95, 331-338 (2014
-
(2014)
Clin. Pharmacol. Ther
, vol.95
, pp. 331-338
-
-
Wei, W.Q.1
-
71
-
-
84948575251
-
CTNNA3, and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies
-
e-pub ahead of print
-
McGeachie M.J., et al. CTNNA3, and SEMA3D: promising loci for asthma exacerbation identified through multiple genome-wide association studies. J. Allergy Clin. Immunol. (2015); e-pub ahead of print
-
(2015)
J. Allergy Clin. Immunol
-
-
McGeachie, M.J.1
-
72
-
-
84929963861
-
A polymorphism in HLA-G modifies statin benefit in asthma
-
Naidoo D., et al. A polymorphism in HLA-G modifies statin benefit in asthma. Pharmacogenom. J. 15, 272-277 (2015
-
(2015)
Pharmacogenom. J.
, vol.15
, pp. 272-277
-
-
Naidoo, D.1
-
73
-
-
84958928109
-
CYP2C19, and CES1 polymorphisms, and efficacy of clopidogrel, and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease
-
Hoh B.L., et al. CYP2C19, and CES1 polymorphisms, and efficacy of clopidogrel, and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease. J. Neurosurg. 1-6 (2015
-
(2015)
J. Neurosurg
, vol.1-6
-
-
Hoh, B.L.1
|