-
1
-
-
84868662780
-
National trends in oral anticoagulant use in the United States, 2007 to 2011
-
Kirley K, Qato DM, Kornfield R, Stafford RS, Alexander GC. National trends in oral anticoagulant use in the United States, 2007 to 2011. Circ Cardiovasc Qual Outcomes 2012; 5: 615-21 .
-
(2012)
Circ Cardiovasc Qual Outcomes
, vol.5
, pp. 615-621
-
-
Kirley, K.1
Qato, D.M.2
Kornfield, R.3
Stafford, R.S.4
Alexander, G.C.5
-
2
-
-
81855169543
-
Emergency hospitalizations for adverse drug events in older Americans
-
Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med 2011; 365: 2002-12 .
-
(2011)
N Engl J Med
, vol.365
, pp. 2002-2012
-
-
Budnitz, D.S.1
Lovegrove, M.C.2
Shehab, N.3
Richards, C.L.4
-
3
-
-
0042387879
-
Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation
-
Hylek EM, Go AS, Chang Y, et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med 2003; 349: 1019-26 .
-
(2003)
N Engl J Med
, vol.349
, pp. 1019-1026
-
-
Hylek, E.M.1
Go, A.S.2
Chang, Y.3
-
4
-
-
34249715284
-
Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation
-
Hylek EM, Evans-Molina C, Shea C, Henault LE, Regan S. Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation. Circulation 2007; 115: 2689-96 .
-
(2007)
Circulation
, vol.115
, pp. 2689-2696
-
-
Hylek, E.M.1
Evans-Molina, C.2
Shea, C.3
Henault, L.E.4
Regan, S.5
-
5
-
-
44949234553
-
Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans
-
Limdi NA, Arnett DK, Goldstein JA, et al. Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans. Pharmacogenomics 2008; 9: 511-26 .
-
(2008)
Pharmacogenomics
, vol.9
, pp. 511-526
-
-
Limdi, N.A.1
Arnett, D.K.2
Goldstein, J.A.3
-
6
-
-
73049117322
-
Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy
-
Ferder N, Eby CS, Deych E, et al. Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy. J Thromb Haemost 2010; 8: 95-100 .
-
(2010)
J Thromb Haemost
, vol.8
, pp. 95-100
-
-
Ferder, N.1
Eby, C.S.2
Deych, E.3
-
7
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder MJ, Reiner AP, Gage BF, et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N Engl J Med 2005; 352: 2285-93 .
-
(2005)
N Engl J Med
, vol.352
, pp. 2285-2293
-
-
Rieder, M.J.1
Reiner, A.P.2
Gage, B.F.3
-
8
-
-
47949086046
-
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
-
Gage B, Eby C, Johnson J, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther 2008; 84: 326-31 .
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 326-331
-
-
Gage, B.1
Eby, C.2
Johnson, J.3
-
9
-
-
51649110496
-
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
-
Cooper GM, Johnson JA, Langaee TY, et al. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood 2008; 112: 1022-27 .
-
(2008)
Blood
, vol.112
, pp. 1022-1027
-
-
Cooper, G.M.1
Johnson, J.A.2
Langaee, T.Y.3
-
10
-
-
63449117825
-
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose
-
Takeuchi F, McGinnis R, Bourgeois S, et al. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet 2009; 5: e1000433 .
-
(2009)
PLoS Genet
, vol.5
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
-
11
-
-
55449100859
-
VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans
-
Limdi NA, Beasley TM, Crowley MR, et al. VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans. Pharmacogenomics 2008; 9: 1445-58 .
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1445-1458
-
-
Limdi, N.A.1
Beasley, T.M.2
Crowley, M.R.3
-
12
-
-
78149256303
-
Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese
-
Cha PC, Mushiroda T, Takahashi A, et al. Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese. Hum Mol Genet 2011; 19: 4735-44 .
-
(2011)
Hum Mol Genet
, vol.19
, pp. 4735-4744
-
-
Cha, P.C.1
Mushiroda, T.2
Takahashi, A.3
-
13
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
Klein TE, Altman RB, Eriksson N, et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 2009; 360: 753-64 .
-
(2009)
N Engl J Med
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
Eriksson, N.3
-
14
-
-
77952570889
-
Warfarin pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across 3 racial groups
-
Limdi NA, Wadelius M, Cavallari L, et al. Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood 2010; 115: 3827-34 .
-
(2010)
Blood
, vol.115
, pp. 3827-3834
-
-
Limdi, N.A.1
Wadelius, M.2
Cavallari, L.3
-
15
-
-
0029667388
-
Global patterns of linkage disequilibrium at the CD4 locus and modern human origins
-
Tishkoff SA, Dietzsch E, Speed W, et al. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 1996; 271: 1380-87 .
-
(1996)
Science
, vol.271
, pp. 1380-1387
-
-
Tishkoff, S.A.1
Dietzsch, E.2
Speed, W.3
-
16
-
-
84862796555
-
Decreased warfarin clearance associated with the CYP2C9 R150H (8) polymorphism
-
Liu Y, Jeong H, Takahashi H, et al. Decreased warfarin clearance associated with the CYP2C9 R150H (8) polymorphism. Clin Pharmacol Ther 2012; 91: 660-65 .
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 660-665
-
-
Liu, Y.1
Jeong, H.2
Takahashi, H.3
-
17
-
-
0031807762
-
Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes
-
Takahashi H, Kashima T, Nomizo Y, et al. Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes. Clin Pharmacol Ther 1998; 63: 519-28 .
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 519-528
-
-
Takahashi, H.1
Kashima, T.2
Nomizo, Y.3
-
18
-
-
78649508578
-
MaCH: Using sequence and genotype data to estimate haplotypes and unobserved genotypes
-
Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol 2010; 34: 816-34 .
-
(2010)
Genet Epidemiol
, vol.34
, pp. 816-834
-
-
Li, Y.1
Willer, C.J.2
Ding, J.3
Scheet, P.4
Abecasis, G.R.5
-
19
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904-09 .
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
20
-
-
70350754462
-
A genome-wide association study of acenocoumarol maintenance dosage
-
Teichert M, Eijgelsheim M, Rivadeneira F, et al. A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet 2009; 18: 3758-68 .
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3758-3768
-
-
Teichert, M.1
Eijgelsheim, M.2
Rivadeneira, F.3
-
21
-
-
79951682471
-
Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients
-
Shahin MH, Khalifa SI, Gong Y, et al. Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients. Pharmacogenet Genomics 2011; 21: 130-35.
-
(2011)
Pharmacogenet Genomics
, vol.21
, pp. 130-135
-
-
Shahin, M.H.1
Khalifa, S.I.2
Gong, Y.3
-
22
-
-
79951811694
-
The missing association: Sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans
-
Perera MA, Gamazon E, Cavallari LH, et al. The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans. Clin Pharmacol Ther 2011; 89: 408-15 .
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 408-415
-
-
Perera, M.A.1
Gamazon, E.2
Cavallari, L.H.3
-
23
-
-
84863229218
-
Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record
-
Ramirez AH, Shi Y, Schildcrout JS, et al. Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record. Pharmacogenomics 2012; 13: 407-18 .
-
(2012)
Pharmacogenomics
, vol.13
, pp. 407-418
-
-
Ramirez, A.H.1
Shi, Y.2
Schildcrout, J.S.3
-
24
-
-
84855921127
-
Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans
-
Cavallari LH, Perera M, Wadelius M, et al. Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans. Pharmacogenet Genomics 2012; 22: 152-58 .
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 152-158
-
-
Cavallari, L.H.1
Perera, M.2
Wadelius, M.3
-
25
-
-
77955764068
-
New genetic variant that might improve warfarin dose prediction in African Americans
-
Schelleman H, Brensinger CM, Chen J, Finkelman BS, Rieder MJ, Kimmel SE. New genetic variant that might improve warfarin dose prediction in African Americans. Br J Clin Pharmacol 2010; 70: 393-99 .
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 393-399
-
-
Schelleman, H.1
Brensinger, C.M.2
Chen, J.3
Finkelman, B.S.4
Rieder, M.J.5
Kimmel, S.E.6
-
26
-
-
77949874684
-
A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans
-
Voora D, Koboldt DC, King CR, et al. A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans. Clin Pharmacol Ther 2010; 87: 445-51.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 445-451
-
-
Voora, D.1
Koboldt, D.C.2
King, C.R.3
-
27
-
-
69249219296
-
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
Shuldiner AR, O'Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009; 302: 849-57 .
-
(2009)
JAMA
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
O'Connell, J.R.2
Bliden, K.P.3
-
28
-
-
84862114807
-
Genetic architecture of microRNA expression: Implications for the transcriptome and complex traits
-
Gamazon ER, Ziliak D, Im HK, et al. Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. Am J Hum Genet 2012; 90: 1046-63 .
-
(2012)
Am J Hum Genet
, vol.90
, pp. 1046-1063
-
-
Gamazon, E.R.1
Ziliak, D.2
Im, H.K.3
-
29
-
-
77949873283
-
Genetic and clinical predictors of warfarin dose requirements in African Americans
-
Cavallari LH, Langaee TY, Momary KM, et al. Genetic and clinical predictors of warfarin dose requirements in African Americans. Clin Pharmacol Ther 2010; 87: 459-64 .
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 459-464
-
-
Cavallari, L.H.1
Langaee, T.Y.2
Momary, K.M.3
-
30
-
-
84883134452
-
-
The National Board of Health and Welfare accessed May 10
-
The National Board of Health and Welfare. Lakemedelsstatistik. http://192.137.163.49/sdb/lak/val.aspx (accessed May 10, 2013).
-
(2013)
Lakemedelsstatistik
-
-
-
31
-
-
84862777241
-
A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II)
-
Anderson JL, Horne BD, Stevens SM, et al. A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II). Circulation 2012; 125: 1997-2005 .
-
(2012)
Circulation
, vol.125
, pp. 1997-2005
-
-
Anderson, J.L.1
Horne, B.D.2
Stevens, S.M.3
-
32
-
-
78349294600
-
Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial
-
French B, Joo J, Geller NL, et al. Statistical design of personalized medicine interventions: the Clarification of Optimal Anticoagulation through Genetics (COAG) trial. Trials 2010; 11: 108 .
-
(2010)
Trials
, vol.11
, pp. 108
-
-
French, B.1
Joo, J.2
Geller, N.L.3
-
33
-
-
70649084116
-
Genotype-guided dosing of coumarin derivatives: The European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design
-
van Schie RM, Wadelius MI, Kamali F, et al. Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design. Pharmacogenomics 2009; 10: 1687-95.
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1687-1695
-
-
Van Schie, R.M.1
Wadelius, M.I.2
Kamali, F.3
|