CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 6, 2015, Pages 1503-1510

  Mcgeachie, Michael J ^a   Wu, Ann C ^b,c   Tse, Sze Man ^a   Clemmer, George L ^a   Sordillo, Joanne ^a   Himes, Blanca E ^d   Lasky Su, Jessica ^a   Chase, Robert P ^a   Martinez, Fernando D ^e   Weeke, Peter ^f,g   Shaffer, Christian M ^f   Xu, Hua ^h   Denny, Josh C ^f   Roden, Dan M ^f   Panettieri, Reynold A ⁱ   Raby, Benjamin A ^a   Weiss, Scott T ^a   Tantisira, Kelan G ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^h UNIVERSITY OF TEXAS   (United States)

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Asthma; biobank; childhood asthma; CTNNA3; exacerbation; expression quantitative trait locus; genome wide association study; SEMA3D

Indexed keywords

ALPHA CATENIN; AZITHROMYCIN; BUDESONIDE; CORTICOSTEROID; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MESSENGER RNA; MONTELUKAST; NEDOCROMIL; PLACEBO; PREDNISONE; PURINERGIC P2X7 RECEPTOR; SEMAPHORIN; SEMAPHORIN 3D; STEROID; UNCLASSIFIED DRUG; CTNNA3 PROTEIN, HUMAN; SEMA3D PROTEIN, HUMAN;

AFRICAN AMERICAN; AIRWAY REMODELING; ALLELE; ARTICLE; ASTHMA; CD4+ T LYMPHOCYTE; COHORT ANALYSIS; CTNNA3 GENE; DISEASE EXACERBATION; ELECTRONIC MEDICAL RECORD; GENE EXPRESSION PROFILING; GENE LOCUS; GENETIC ASSOCIATION; HOMOZYGOTE; HUMAN; IMMUNE RESPONSE; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEMA3D GENE; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; ADULT; CHILD; FEMALE; GENETICS; GENOME-WIDE ASSOCIATION STUDY; INFANT; MALE; METABOLISM; PRESCHOOL CHILD; SEQUENCE ANALYSIS; YOUNG ADULT;

ADOLESCENT; ADULT; ALPHA CATENIN; ASTHMA; CHILD; CHILD, PRESCHOOL; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INFANT; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; SEMAPHORINS; SEQUENCE ANALYSIS, RNA; YOUNG ADULT;

EID: 84948575251     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.04.039     Document Type: Article

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