Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology

EBioMedicine

Volumn 2, Issue 12, 2015, Pages 2087-2093

  Wong, Hector R ^a,b   Cvijanovich, Natalie Z ^c   Anas, Nick ^d   Allen, Geoffrey L ^e   Thomas, Neal J ^f   Bigham, Michael T ^g   Weiss, Scott L ^h   Fitzgerald, Julie ^h   Checchia, Paul A ⁱ   Meyer, Keith ^j   Quasney, Michael ^k   Hall, Mark ^l   Gedeit, Rainer ^m   Freishtat, Robert J ⁿ   Nowak, Jeffrey ^o   Raj, Shekhar S ^p   Gertz, Shira ^q   Howard, Kelli ^a   Harmon, Kelli ^a   Lahni, Patrick ^a   Frank, Erin ^a   Hart, Kimberly W ^b   Lindsell, Christopher J ^b   more..

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

^d CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

^e CHILDREN S MERCY HOSPITAL   (United States)

^f PENN STATE CHILDREN S HOSPITAL   (United States)

^g AKRON CHILDREN'S HOSPITAL   (United States)

^h CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

ⁱ TEXAS CHILDREN S HOSPITAL   (United States)

^j MIAMI CHILDREN'S HOSPITAL   (United States)

^k UNIVERSITY OF MICHIGAN   (United States)

^l NATIONWIDE CHILDREN S HOSPITAL   (United States)

^m Children's Hospital of Wisconsin   (United States)

ⁿ CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^o CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

^p RILEY HOSPITAL FOR CHILDREN   (United States)

^q HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

more..

Author keywords

Biomarkers; Endotype; Immune Suppression; Inflammation; Modeling; Outcome; Prediction; Sepsis

Indexed keywords

GRANZYME B; HEAT SHOCK PROTEIN 70; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MATRIX METALLOPROTEINASE; BIOLOGICAL MARKER;

ACCURACY STUDY; ARTICLE; BONE MARROW TRANSPLANTATION; CHILD; COHORT ANALYSIS; DISEASE MODEL; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; MALE; MORTALITY; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SECONDARY INFECTION; SENSITIVITY ANALYSIS; SEPTIC SHOCK; TRAINING; VALIDATION PROCESS; ADOLESCENT; AREA UNDER THE CURVE; INFANT; METABOLISM; OUTCOME ASSESSMENT; PROGNOSIS; REPRODUCIBILITY; RISK; SENSITIVITY AND SPECIFICITY; SHOCK, SEPTIC; THEORETICAL MODEL;

ADOLESCENT; AREA UNDER CURVE; BIOMARKERS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; HUMANS; INFANT; MALE; MODELS, THEORETICAL; PATIENT OUTCOME ASSESSMENT; PROGNOSIS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RISK; SENSITIVITY AND SPECIFICITY; SHOCK, SEPTIC;

EID: 84958836185     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.11.035     Document Type: Article

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