-
1
-
-
84880626687
-
Integrative genomic analysis of the human immune response to influenza vaccination
-
Franco, L. M. et al. Integrative genomic analysis of the human immune response to influenza vaccination. eLife 2, e00299, doi: 10.7554/eLife.00299 (2013).
-
(2013)
ELife
, vol.2
, pp. e00299
-
-
Franco, L.M.1
-
2
-
-
84901687604
-
Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses
-
Avnir, Y. et al. Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses. PLoS pathogens 10, e1004103, doi: 10.1371/journal.ppat.1004103 (2014).
-
(2014)
PLoS Pathogens
, vol.10
, pp. e1004103
-
-
Avnir, Y.1
-
3
-
-
84875948859
-
Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation
-
Watson, C. T. et al. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. American journal of human genetics 92, 530-546, doi: 10.1016/j. ajhg.2013.03.004 (2013).
-
(2013)
American Journal of Human Genetics
, vol.92
, pp. 530-546
-
-
Watson, C.T.1
-
4
-
-
84964315189
-
Immunoglobulins: 25 years of immunoinformatics and IMGT-ONTOLOGY
-
Lefranc, M. P. Immunoglobulins: 25 years of immunoinformatics and IMGT-ONTOLOGY. Biomolecules 4, 1102-1139, doi: 10.3390/biom4041102 (2014).
-
(2014)
Biomolecules
, vol.4
, pp. 1102-1139
-
-
Lefranc, M.P.1
-
5
-
-
0027278935
-
A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles
-
Sasso, E. H., Willems van Dijk, K., Bull, A. P., Milner, E. C. A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles. The Journal of clinical investigation 91, 2358-2367, doi: 10.1172/JCI116468 (1993).
-
(1993)
The Journal of Clinical Investigation
, vol.91
, pp. 2358-2367
-
-
Sasso, E.H.1
Willems Van Dijk, K.2
Bull, A.P.3
Milner, E.C.4
-
6
-
-
0029555052
-
Polymorphism and utilization of human VH Genes
-
Milner, E. C., Hufnagle, W. O., Glas, A. M., Suzuki, I., Alexander, C. Polymorphism and utilization of human VH Genes. Annals of the New York Academy of Sciences 764, 50-61 (1995).
-
(1995)
Annals of the New York Academy of Sciences
, vol.764
, pp. 50-61
-
-
Milner, E.C.1
Hufnagle, W.O.2
Glas, A.M.3
Suzuki, I.4
Alexander, C.5
-
7
-
-
84866949036
-
Structural and genetic basis for development of broadly neutralizing influenza antibodies
-
Lingwood, D. et al. Structural and genetic basis for development of broadly neutralizing influenza antibodies. Nature 489, 566-570, doi: 10.1038/nature11371 (2012).
-
(2012)
Nature
, vol.489
, pp. 566-570
-
-
Lingwood, D.1
-
8
-
-
58049198443
-
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
-
Throsby, M. et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PloS one 3, e3942, doi: 10.1371/journal.pone.0003942 (2008).
-
(2008)
PloS One
, vol.3
, pp. e3942
-
-
Throsby, M.1
-
9
-
-
84922225958
-
Rapid development of broadly influenza neutralizing antibodies through redundant mutations
-
Pappas, L. et al. Rapid development of broadly influenza neutralizing antibodies through redundant mutations. Nature 516, 418-422, doi: 10.1038/nature13764 (2014).
-
(2014)
Nature
, vol.516
, pp. 418-422
-
-
Pappas, L.1
-
10
-
-
84936803233
-
H5N1 Vaccine-Elicited Memory B cells are genetically constrained by the IGHV Locus in the recognition of a neutralizing epitope in the hemagglutinin stem
-
Wheatley, A. K. et al. H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem. Journal of immunology 195, 602-610, doi: 10.4049/jimmunol.1402835 (2015).
-
(2015)
Journal of Immunology
, vol.195
, pp. 602-610
-
-
Wheatley, A.K.1
-
11
-
-
84940192994
-
Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
-
Williams, W. B. et al. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science, doi: 10.1126/science.aab1253 (2015).
-
(2015)
Science
-
-
Williams, W.B.1
-
12
-
-
0029664291
-
Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number
-
Sasso, E. H., Johnson, T., Kipps, T. J. Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number. The Journal of clinical investigation 97, 2074-2080, doi: 10.1172/JCI118644 (1996).
-
(1996)
The Journal of Clinical Investigation
, vol.97
, pp. 2074-2080
-
-
Sasso, E.H.1
Johnson, T.2
Kipps, T.J.3
-
13
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Abecasis, G. R. et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073, doi: 10.1038/nature09534 (2010).
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Abecasis, G.R.1
-
14
-
-
84055181361
-
Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation
-
Glanville, J. et al. Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proceedings of the National Academy of Sciences of the United States of America. 108, 20066-20071, doi: 10.1073/pnas.1107498108 (2011).
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 20066-20071
-
-
Glanville, J.1
-
15
-
-
84896917279
-
Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages
-
Whittle, J. R. et al. Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages. Journal of virology. 88, 4047-4057, doi: 10.1128/JVI.03422-13 (2014).
-
(2014)
Journal of Virology.
, vol.88
, pp. 4047-4057
-
-
Whittle, J.R.1
-
16
-
-
82455164195
-
Enhancer-promoter communication and transcriptional regulation of Igh
-
Roy, A. L., Sen, R., Roeder, R. G. Enhancer-promoter communication and transcriptional regulation of Igh. Trends in immunology 32, 532-539, doi: 10.1016/j.it.2011.06.012 (2011).
-
(2011)
Trends in Immunology
, vol.32
, pp. 532-539
-
-
Roy, A.L.1
Sen, R.2
Roeder, R.G.3
-
17
-
-
84865760395
-
GENCODE: The reference human genome annotation for the ENCODE Project
-
Harrow, J. et al. GENCODE: the reference human genome annotation for The ENCODE Project. Genome research 22, 1760-1774, doi: 10.1101/gr.135350.111 (2012).
-
(2012)
Genome Research
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
-
18
-
-
0036232830
-
Expression of transcription factor AML-2 (RUNX3, CBF(alpha)-3) is induced by Epstein-Barr virus EBNA-2 and correlates with the B-cell activation phenotype
-
Spender, L. C., Cornish, G. H., Sullivan, A., Farrell, P. J. Expression of transcription factor AML-2 (RUNX3, CBF(alpha)-3) is induced by Epstein-Barr virus EBNA-2 and correlates with the B-cell activation phenotype. Journal of virology 76, 4919-4927 (2002).
-
(2002)
Journal of Virology
, vol.76
, pp. 4919-4927
-
-
Spender, L.C.1
Cornish, G.H.2
Sullivan, A.3
Farrell, P.J.4
-
19
-
-
70149090670
-
RUNX3-mediated repression of RUNX1 in B cells
-
Brady, G., Farrell, P. J. RUNX3-mediated repression of RUNX1 in B cells. Journal of cellular physiology 221, 283-287, doi: 10.1002/jcp.21880 (2009).
-
(2009)
Journal of Cellular Physiology
, vol.221
, pp. 283-287
-
-
Brady, G.1
Farrell, P.J.2
-
20
-
-
84864153342
-
The immunoglobulin heavy chain locus: Genetic variation, missing data, and implications for human disease
-
Watson, C. T., Breden, F. The immunoglobulin heavy chain locus: genetic variation, missing data, and implications for human disease. Genes and immunity 13, 363-373, doi: 10.1038/gene.2012.12 (2012).
-
(2012)
Genes and Immunity
, vol.13
, pp. 363-373
-
-
Watson, C.T.1
Breden, F.2
-
22
-
-
69149086060
-
Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine
-
Beigel, J. H., Voell, J., Huang, C. Y., Burbelo, P. D., Lane, H. C. Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine. The Journal of infectious diseases. 200, 501-509, doi: 10.1086/599992 (2009).
-
(2009)
The Journal of Infectious Diseases
, vol.200
, pp. 501-509
-
-
Beigel, J.H.1
Voell, J.2
Huang, C.Y.3
Burbelo, P.D.4
Lane, H.C.5
-
23
-
-
84901304592
-
Alternative recognition of the conserved stem epitope in influenza A virus hemagglutinin by a VH3-30-encoded heterosubtypic antibody
-
Wyrzucki, A. et al. Alternative recognition of the conserved stem epitope in influenza A virus hemagglutinin by a VH3-30-encoded heterosubtypic antibody. Journal of virology. 88, 7083-7092, doi: 10.1128/JVI.00178-14 (2014).
-
(2014)
Journal of Virology
, vol.88
, pp. 7083-7092
-
-
Wyrzucki, A.1
-
24
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
Corti, D. et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 333, 850-856, doi: 10.1126/science.1205669 (2011).
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
-
25
-
-
84880427552
-
An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies
-
Nakamura, G. et al. An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies. Cell host & microbe 14, 93-103, doi: 10.1016/j.chom.2013.06.004 (2013).
-
(2013)
Cell Host & Microbe
, vol.14
, pp. 93-103
-
-
Nakamura, G.1
-
26
-
-
0029416814
-
Ethnic differences in VH gene polymorphism
-
Sasso, E. H., Buckner, J. H., Suzuki, L. A. Ethnic differences in VH gene polymorphism. Annals of the New York Academy of Sciences 764, 72-73 (1995).
-
(1995)
Annals of the New York Academy of Sciences
, vol.764
, pp. 72-73
-
-
Sasso, E.H.1
Buckner, J.H.2
Suzuki, L.A.3
-
27
-
-
0027169934
-
Polymorphism of the human immunoglobulin variable region segment V1-4.1
-
Shin, E. K. et al. Polymorphism of the human immunoglobulin variable region segment V1-4.1. Immunogenetics. 38, 304-306 (1993).
-
(1993)
Immunogenetics.
, vol.38
, pp. 304-306
-
-
Shin, E.K.1
-
28
-
-
84923172329
-
High preexisting serological antibody levels correlate with diversification of the influenza vaccine response
-
Andrews, S. F. et al. High preexisting serological antibody levels correlate with diversification of the influenza vaccine response. Journal of virology 89, 3308-3317, doi: 10.1128/JVI.02871-14 (2015).
-
(2015)
Journal of Virology
, vol.89
, pp. 3308-3317
-
-
Andrews, S.F.1
-
29
-
-
84924034216
-
Preexisting human antibodies neutralize recently emerged H7N9 influenza strains
-
Henry Dunand, C. J. et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. The Journal of clinical investigation 125, 1255-1268, doi: 10.1172/JCI74374 (2015).
-
(2015)
The Journal of Clinical Investigation
, vol.125
, pp. 1255-1268
-
-
Henry Dunand, C.J.1
-
30
-
-
84890965081
-
Universal influenza virus vaccines: Need for clinical trials
-
Krammer, F., Palese, P. Universal influenza virus vaccines: need for clinical trials. Nature immunology. 15, 3-5, doi: 10.1038/ni.2761 (2014).
-
(2014)
Nature Immunology.
, vol.15
, pp. 3-5
-
-
Krammer, F.1
Palese, P.2
-
31
-
-
84878611784
-
Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
-
Krammer, F., Pica, N., Hai, R., Margine, I., Palese, P. Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. Journal of virology 87, 6542-6550, doi: 10.1128/JVI.00641-13 (2013).
-
(2013)
Journal of Virology
, vol.87
, pp. 6542-6550
-
-
Krammer, F.1
Pica, N.2
Hai, R.3
Margine, I.4
Palese, P.5
-
32
-
-
84931573106
-
Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses
-
Wohlbold, T. J. et al. Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses. Vaccine 33, 3314-3321, doi: 10.1016/j.vaccine.2015.05.038 (2015).
-
(2015)
Vaccine
, vol.33
, pp. 3314-3321
-
-
Wohlbold, T.J.1
-
33
-
-
84941023600
-
Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
-
Yassine, H. M. et al. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nature medicine 21, 1065-1070, doi: 10.1038/nm.3927 (2015).
-
(2015)
Nature Medicine
, vol.21
, pp. 1065-1070
-
-
Yassine, H.M.1
-
34
-
-
84941873935
-
A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen
-
Impagliazzo, A. et al. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science, doi: 10.1126/science.aac7263 (2015).
-
(2015)
Science
-
-
Impagliazzo, A.1
-
35
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui, J. et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nature structural & molecular biology 16, 265-273, doi: 10.1038/nsmb.1566 (2009).
-
(2009)
Nature Structural & Molecular Biology
, vol.16
, pp. 265-273
-
-
Sui, J.1
-
36
-
-
84860494449
-
Antibody repertoires in humanized NOD-scid-IL2Rgamma(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse
-
Ippolito, G. C. et al. Antibody repertoires in humanized NOD-scid-IL2Rgamma(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse. PloS one 7, e35497, doi: 10.1371/journal.pone.0035497 (2012).
-
(2012)
PloS One
, vol.7
, pp. e35497
-
-
Ippolito, G.C.1
-
37
-
-
0032587915
-
Molecular characterization of the VH1-specific variable region determinants recognized by anti-idiotypic monoclonal antibodies G6 and G8
-
Potter, K. N., Li, Y., Mageed, R. A., Jefferis, R., Capra, J. D. Molecular characterization of the VH1-specific variable region determinants recognized by anti-idiotypic monoclonal antibodies G6 and G8. Scandinavian journal of immunology 50, 14-20 (1999).
-
(1999)
Scandinavian Journal of Immunology
, vol.50
, pp. 14-20
-
-
Potter, K.N.1
Li, Y.2
Mageed, R.A.3
Jefferis, R.4
Capra, J.D.5
-
39
-
-
73949116413
-
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire
-
Glanville, J. et al. Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire. Proceedings of the National Academy of Sciences of the United States of America 106, 20216-20221, doi: 10.1073/pnas.0909775106 (2009).
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 20216-20221
-
-
Glanville, J.1
|