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Volumn 33, Issue 29, 2015, Pages 3314-3321

Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses

Author keywords

HA stalk; Headless hemagglutinin; Heterosubtypic immunity; Influenza virus; Universal influenza virus vaccine

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; NEUTRALIZING ANTIBODY; INFLUENZA VACCINE;

EID: 84931573106     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.05.038     Document Type: Article
Times cited : (73)

References (50)
  • 1
    • 0037402228 scopus 로고    scopus 로고
    • The annual production cycle for influenza vaccine
    • Gerdil C. The annual production cycle for influenza vaccine. Vaccine 2003, 21:1776-1779.
    • (2003) Vaccine , vol.21 , pp. 1776-1779
    • Gerdil, C.1
  • 2
    • 84879212793 scopus 로고    scopus 로고
    • Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis
    • Tricco A.C., Chit A., Soobiah C., Hallett D., Meier G., Chen M.H., et al. Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis. BMC Med 2013, 11:153.
    • (2013) BMC Med , vol.11 , pp. 153
    • Tricco, A.C.1    Chit, A.2    Soobiah, C.3    Hallett, D.4    Meier, G.5    Chen, M.H.6
  • 3
    • 10944240992 scopus 로고    scopus 로고
    • Influenza: old and new threats
    • Palese P. Influenza: old and new threats. Nat Med 2004, 10:S82-S87.
    • (2004) Nat Med , vol.10 , pp. S82-S87
    • Palese, P.1
  • 4
    • 84928825136 scopus 로고    scopus 로고
    • Emerging influenza viruses and the prospect of a universal influenza virus vaccine
    • Krammer F. Emerging influenza viruses and the prospect of a universal influenza virus vaccine. Biotechnol J 2015.
    • (2015) Biotechnol J
    • Krammer, F.1
  • 5
    • 84885953445 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin stalk-based antibodies and vaccines
    • Krammer F., Palese P. Influenza virus hemagglutinin stalk-based antibodies and vaccines. Curr Opin Virol 2013, 3:521-530.
    • (2013) Curr Opin Virol , vol.3 , pp. 521-530
    • Krammer, F.1    Palese, P.2
  • 6
    • 84890281675 scopus 로고    scopus 로고
    • Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins
    • Heaton N.S., Sachs D., Chen C.J., Hai R., Palese P. Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. Proc Natl Acad Sci U S A 2013, 110:20248-20253.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 20248-20253
    • Heaton, N.S.1    Sachs, D.2    Chen, C.J.3    Hai, R.4    Palese, P.5
  • 7
    • 0019827545 scopus 로고
    • Antigenic structure of influenza virus haemagglutinin defined by hybridoma antibodies
    • Gerhard W., Yewdell J., Frankel M.E., Webster R. Antigenic structure of influenza virus haemagglutinin defined by hybridoma antibodies. Nature 1981, 290:713-717.
    • (1981) Nature , vol.290 , pp. 713-717
    • Gerhard, W.1    Yewdell, J.2    Frankel, M.E.3    Webster, R.4
  • 8
    • 0027471177 scopus 로고
    • A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains
    • Okuno Y., Isegawa Y., Sasao F., Ueda S. A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J Virol 1993, 67:2552-2558.
    • (1993) J Virol , vol.67 , pp. 2552-2558
    • Okuno, Y.1    Isegawa, Y.2    Sasao, F.3    Ueda, S.4
  • 9
    • 84863597077 scopus 로고    scopus 로고
    • A pan-h1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo
    • Tan G.S., Krammer F., Eggink D., Kongchanagul A., Moran T.M., Palese P. A pan-h1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J Virol 2012, 86:6179-6188.
    • (2012) J Virol , vol.86 , pp. 6179-6188
    • Tan, G.S.1    Krammer, F.2    Eggink, D.3    Kongchanagul, A.4    Moran, T.M.5    Palese, P.6
  • 12
    • 80051670323 scopus 로고    scopus 로고
    • A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
    • Corti D., Voss J., Gamblin S.J., Codoni G., Macagno A., Jarrossay D., et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 2011, 333:850-856.
    • (2011) Science , vol.333 , pp. 850-856
    • Corti, D.1    Voss, J.2    Gamblin, S.J.3    Codoni, G.4    Macagno, A.5    Jarrossay, D.6
  • 13
    • 84924034216 scopus 로고    scopus 로고
    • Preexisting human antibodies neutralize recently emerged H7N9 influenza strains
    • Henry Dunand C.J., Leon P.E., Kaur K., Tan G.S., Zheng N.Y., Andrews S., et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. J Clin Invest 2015, 125:1255-1268.
    • (2015) J Clin Invest , vol.125 , pp. 1255-1268
    • Henry Dunand, C.J.1    Leon, P.E.2    Kaur, K.3    Tan, G.S.4    Zheng, N.Y.5    Andrews, S.6
  • 14
    • 62049083943 scopus 로고    scopus 로고
    • Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
    • Sui J., Hwang W.C., Perez S., Wei G., Aird D., Chen L.M., et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 2009, 16:265-273.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 265-273
    • Sui, J.1    Hwang, W.C.2    Perez, S.3    Wei, G.4    Aird, D.5    Chen, L.M.6
  • 15
    • 84875776863 scopus 로고    scopus 로고
    • H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice
    • Margine I., Hai R., Albrecht R.A., Obermoser G., Harrod A.C., Banchereau J., et al. H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice. J Virol 2013, 87:4728-4737.
    • (2013) J Virol , vol.87 , pp. 4728-4737
    • Margine, I.1    Hai, R.2    Albrecht, R.A.3    Obermoser, G.4    Harrod, A.C.5    Banchereau, J.6
  • 16
    • 44449118948 scopus 로고    scopus 로고
    • Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
    • Wrammert J., Smith K., Miller J., Langley W.A., Kokko K., Larsen C., et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 2008, 453:667-671.
    • (2008) Nature , vol.453 , pp. 667-671
    • Wrammert, J.1    Smith, K.2    Miller, J.3    Langley, W.A.4    Kokko, K.5    Larsen, C.6
  • 17
    • 80054780343 scopus 로고    scopus 로고
    • H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination
    • Moody M.A., Zhang R., Walter E.B., Woods C.W., Ginsburg G.S., McClain M.T., et al. H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. PLoS ONE 2011, 6:e25797.
    • (2011) PLoS ONE , vol.6 , pp. e25797
    • Moody, M.A.1    Zhang, R.2    Walter, E.B.3    Woods, C.W.4    Ginsburg, G.S.5    McClain, M.T.6
  • 18
    • 84869059071 scopus 로고    scopus 로고
    • Hemagglutinin stalk-reactive antibodies are boosted following sequential infection with seasonal and pandemic H1N1 influenza virus in mice
    • Krammer F., Pica N., Hai R., Tan G.S., Palese P. Hemagglutinin stalk-reactive antibodies are boosted following sequential infection with seasonal and pandemic H1N1 influenza virus in mice. J Virol 2012, 86:10302-10307.
    • (2012) J Virol , vol.86 , pp. 10302-10307
    • Krammer, F.1    Pica, N.2    Hai, R.3    Tan, G.S.4    Palese, P.5
  • 19
    • 59649084891 scopus 로고    scopus 로고
    • Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza
    • Steel J., Lowen A.C., Pena L., Angel M., Solorzano A., Albrecht R., et al. Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza. J Virol 2009, 83:1742-1753.
    • (2009) J Virol , vol.83 , pp. 1742-1753
    • Steel, J.1    Lowen, A.C.2    Pena, L.3    Angel, M.4    Solorzano, A.5    Albrecht, R.6
  • 20
    • 84896979547 scopus 로고    scopus 로고
    • Divergent H7 immunogens offer protection from H7N9 virus challenge
    • Krammer F., Albrecht R.A., Tan G.S., Margine I., Hai R., Schmolke M., et al. Divergent H7 immunogens offer protection from H7N9 virus challenge. J Virol 2014, 88:3976-3985.
    • (2014) J Virol , vol.88 , pp. 3976-3985
    • Krammer, F.1    Albrecht, R.A.2    Tan, G.S.3    Margine, I.4    Hai, R.5    Schmolke, M.6
  • 21
    • 77954951040 scopus 로고    scopus 로고
    • Trichoplusia ni cells (High Five) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines
    • Krammer F., Schinko T., Palmberger D., Tauer C., Messner P., Grabherr R. Trichoplusia ni cells (High Five) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines. Mol Biotechnol 2010, 45:226-234.
    • (2010) Mol Biotechnol , vol.45 , pp. 226-234
    • Krammer, F.1    Schinko, T.2    Palmberger, D.3    Tauer, C.4    Messner, P.5    Grabherr, R.6
  • 22
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
    • Krammer F., Pica N., Hai R., Margine I., Palese P. Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. J Virol 2013, 87:6542-6550.
    • (2013) J Virol , vol.87 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palese, P.5
  • 23
    • 84865289490 scopus 로고    scopus 로고
    • A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates
    • Krammer F., Margine I., Tan G.S., Pica N., Krause J.C., Palese P. A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates. PLOS ONE 2012, 7:e43603.
    • (2012) PLOS ONE , vol.7 , pp. e43603
    • Krammer, F.1    Margine, I.2    Tan, G.S.3    Pica, N.4    Krause, J.C.5    Palese, P.6
  • 24
    • 79952140653 scopus 로고    scopus 로고
    • Influenza virus vaccine based on the conserved hemagglutinin stalk domain
    • Steel J., Lowen A.C., Wang T.T., Yondola M., Gao Q., Haye K., et al. Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio 2010, 1:1-9.
    • (2010) MBio , vol.1 , pp. 1-9
    • Steel, J.1    Lowen, A.C.2    Wang, T.T.3    Yondola, M.4    Gao, Q.5    Haye, K.6
  • 25
    • 84896720205 scopus 로고    scopus 로고
    • Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system
    • Margine I., Palese P., Krammer F. Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system. J Vis Exp 2013.
    • (2013) J Vis Exp
    • Margine, I.1    Palese, P.2    Krammer, F.3
  • 26
    • 84880617786 scopus 로고    scopus 로고
    • In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies
    • Heaton N.S., Leyva-Grado V.H., Tan G.S., Eggink D., Hai R., Palese P. In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. J Virol 2013, 87:8272-8281.
    • (2013) J Virol , vol.87 , pp. 8272-8281
    • Heaton, N.S.1    Leyva-Grado, V.H.2    Tan, G.S.3    Eggink, D.4    Hai, R.5    Palese, P.6
  • 27
    • 84861325359 scopus 로고    scopus 로고
    • Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes
    • Hai R., Krammer F., Tan G.S., Pica N., Eggink D., Maamary J., et al. Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. J Virol 2012, 86:5774-5781.
    • (2012) J Virol , vol.86 , pp. 5774-5781
    • Hai, R.1    Krammer, F.2    Tan, G.S.3    Pica, N.4    Eggink, D.5    Maamary, J.6
  • 28
    • 0027513851 scopus 로고
    • Induction of antihemagglutinin antibodies by polyclonal antiidiotype antibodies
    • Dinca L., Neuwirth S., Schulman J., Bona C. Induction of antihemagglutinin antibodies by polyclonal antiidiotype antibodies. Viral Immunol 1993, 6:75-84.
    • (1993) Viral Immunol , vol.6 , pp. 75-84
    • Dinca, L.1    Neuwirth, S.2    Schulman, J.3    Bona, C.4
  • 31
    • 0020626189 scopus 로고
    • Preparation of influenza virus subviral particles lacking the HA1 subunit of hemagglutinin: unmasking of cross-reactive HA2 determinants
    • Graves P.N., Schulman J.L., Young J.F., Palese P. Preparation of influenza virus subviral particles lacking the HA1 subunit of hemagglutinin: unmasking of cross-reactive HA2 determinants. Virology 1983, 126:106-116.
    • (1983) Virology , vol.126 , pp. 106-116
    • Graves, P.N.1    Schulman, J.L.2    Young, J.F.3    Palese, P.4
  • 32
    • 0034286992 scopus 로고    scopus 로고
    • In vivo acute depletion of CD8(+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells
    • Salem M.L., Hossain M.S. In vivo acute depletion of CD8(+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells. Int J Immunopharmacol 2000, 22:707-718.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 707-718
    • Salem, M.L.1    Hossain, M.S.2
  • 33
    • 84908389429 scopus 로고    scopus 로고
    • Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans
    • Nachbagauer R., Wohlbold T.J., Hirsh A., Hai R., Sjursen H., Palese P., et al. Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans. J Virol 2014, 88:13260-13268.
    • (2014) J Virol , vol.88 , pp. 13260-13268
    • Nachbagauer, R.1    Wohlbold, T.J.2    Hirsh, A.3    Hai, R.4    Sjursen, H.5    Palese, P.6
  • 34
    • 84906996647 scopus 로고    scopus 로고
    • Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans
    • Ellebedy A.H., Krammer F., Li G.M., Miller M.S., Chiu C., Wrammert J., et al. Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans. Proc Natl Acad Sci U S A 2014, 111:13133-13138.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 13133-13138
    • Ellebedy, A.H.1    Krammer, F.2    Li, G.M.3    Miller, M.S.4    Chiu, C.5    Wrammert, J.6
  • 35
    • 84863115945 scopus 로고    scopus 로고
    • Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
    • Pica N., Hai R., Krammer F., Wang T.T., Maamary J., Eggink D., et al. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proc Natl Acad Sci U S A 2012, 109:2573-2578.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2573-2578
    • Pica, N.1    Hai, R.2    Krammer, F.3    Wang, T.T.4    Maamary, J.5    Eggink, D.6
  • 36
    • 77956379133 scopus 로고    scopus 로고
    • Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge
    • Bommakanti G., Citron M.P., Hepler R.W., Callahan C., Heidecker G.J., Najar T.A., et al. Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge. Proc Natl Acad Sci U S A 2010, 107:13701-13706.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13701-13706
    • Bommakanti, G.1    Citron, M.P.2    Hepler, R.W.3    Callahan, C.4    Heidecker, G.J.5    Najar, T.A.6
  • 37
    • 84870656355 scopus 로고    scopus 로고
    • Design of Escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge
    • Bommakanti G., Lu X., Citron M.P., Najar T.A., Heidecker G.J., ter Meulen J., et al. Design of Escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge. J Virol 2012, 86:13434-13444.
    • (2012) J Virol , vol.86 , pp. 13434-13444
    • Bommakanti, G.1    Lu, X.2    Citron, M.P.3    Najar, T.A.4    Heidecker, G.J.5    ter Meulen, J.6
  • 38
    • 84884206717 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin
    • Mallajosyula V.V., Citron M., Lu X., Meulen J.T., Varadarajan R., Liang X. In vitro and in vivo characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin. Proteins 2013, 81:1759-1775.
    • (2013) Proteins , vol.81 , pp. 1759-1775
    • Mallajosyula, V.V.1    Citron, M.2    Lu, X.3    Meulen, J.T.4    Varadarajan, R.5    Liang, X.6
  • 39
    • 84903476533 scopus 로고    scopus 로고
    • Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection
    • Mallajosyula V.V., Citron M., Ferrara F., Lu X., Callahan C., Heidecker G.J., et al. Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection. Proc Natl Acad Sci U S A 2014, 111:E2514-E2523.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. E2514-E2523
    • Mallajosyula, V.V.1    Citron, M.2    Ferrara, F.3    Lu, X.4    Callahan, C.5    Heidecker, G.J.6
  • 40
    • 84891912497 scopus 로고    scopus 로고
    • Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines
    • Lu Y., Welsh J.P., Swartz J.R. Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines. Proc Natl Acad Sci U S A 2014, 111:125-130.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 125-130
    • Lu, Y.1    Welsh, J.P.2    Swartz, J.R.3
  • 41
    • 84893496184 scopus 로고    scopus 로고
    • H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge
    • Krammer F., Margine I., Hai R., Flood A., Hirsh A., Tsvetnitsky V., et al. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J Virol 2014, 88:2340-2343.
    • (2014) J Virol , vol.88 , pp. 2340-2343
    • Krammer, F.1    Margine, I.2    Hai, R.3    Flood, A.4    Hirsh, A.5    Tsvetnitsky, V.6
  • 42
    • 84885950726 scopus 로고    scopus 로고
    • Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses
    • Margine I., Krammer F., Hai R., Heaton N.S., Tan G.S., Andrews S.A., et al. Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses. J Virol 2013, 87:10435-10446.
    • (2013) J Virol , vol.87 , pp. 10435-10446
    • Margine, I.1    Krammer, F.2    Hai, R.3    Heaton, N.S.4    Tan, G.S.5    Andrews, S.A.6
  • 43
    • 84883856356 scopus 로고    scopus 로고
    • Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis
    • Miller M.S., Gardner T.J., Krammer F., Aguado L.C., Tortorella D., Basler C.F., et al. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Sci Transl Med 2013, 5:198ra07.
    • (2013) Sci Transl Med , vol.5 , pp. 07-198
    • Miller, M.S.1    Gardner, T.J.2    Krammer, F.3    Aguado, L.C.4    Tortorella, D.5    Basler, C.F.6
  • 44
    • 84862908804 scopus 로고    scopus 로고
    • Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies
    • Terajima M., Cruz J., Co M.D., Lee J.H., Kaur K., Wrammert J., et al. Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies. J Virol 2011, 85:13463-13467.
    • (2011) J Virol , vol.85 , pp. 13463-13467
    • Terajima, M.1    Cruz, J.2    Co, M.D.3    Lee, J.H.4    Kaur, K.5    Wrammert, J.6
  • 45
    • 84893797938 scopus 로고    scopus 로고
    • Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo
    • Dilillo D.J., Tan G.S., Palese P., Ravetch J.V. Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo. Nat Med 2014, 20:143-151.
    • (2014) Nat Med , vol.20 , pp. 143-151
    • Dilillo, D.J.1    Tan, G.S.2    Palese, P.3    Ravetch, J.V.4
  • 46
    • 84877317499 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques
    • Jegaskanda S., Weinfurter J.T., Friedrich T.C., Kent S.J. Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques. J Virol 2013, 87:5512-5522.
    • (2013) J Virol , vol.87 , pp. 5512-5522
    • Jegaskanda, S.1    Weinfurter, J.T.2    Friedrich, T.C.3    Kent, S.J.4
  • 47
    • 84873547392 scopus 로고    scopus 로고
    • Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies
    • Jegaskanda S., Job E.R., Kramski M., Laurie K., Isitman G., de Rose R., et al. Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies. J Immunol 2013, 190:1837-1848.
    • (2013) J Immunol , vol.190 , pp. 1837-1848
    • Jegaskanda, S.1    Job, E.R.2    Kramski, M.3    Laurie, K.4    Isitman, G.5    de Rose, R.6
  • 48
    • 84904263611 scopus 로고    scopus 로고
    • Influenza-specific antibody-dependent cellular cytotoxicity: toward a universal influenza vaccine
    • Jegaskanda S., Reading P.C., Kent S.J. Influenza-specific antibody-dependent cellular cytotoxicity: toward a universal influenza vaccine. J Immunol 2014, 193:469-475.
    • (2014) J Immunol , vol.193 , pp. 469-475
    • Jegaskanda, S.1    Reading, P.C.2    Kent, S.J.3
  • 49
    • 84896019901 scopus 로고    scopus 로고
    • Eliciting broadly protective antibody responses against influenza
    • Kirchenbaum G.A., Ross T.M. Eliciting broadly protective antibody responses against influenza. Curr Opin Immunol 2014, 28:71-76.
    • (2014) Curr Opin Immunol , vol.28 , pp. 71-76
    • Kirchenbaum, G.A.1    Ross, T.M.2
  • 50
    • 84924060844 scopus 로고    scopus 로고
    • Advances in the development of influenza virus vaccines
    • Krammer F., Palese P. Advances in the development of influenza virus vaccines. Nat Rev Drug Discov 2015, 14:167-182.
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 167-182
    • Krammer, F.1    Palese, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.