Glucose Alters Per2 Rhythmicity Independent of AMPK, whereas AMPK Inhibitor Compound C Causes Profound Repression of Clock Genes and AgRP in mHypoE-37 Hypothalamic Neurons

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Oosterman, Johanneke E ^a,b   Belsham, Denise D ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DORSOMORPHIN; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; AGOUTI RELATED PROTEIN; AGRP PROTEIN, MOUSE; ARNTL PROTEIN, MOUSE; CIRCADIAN RHYTHM SIGNALING PROTEIN; PER2 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK;

AGRP GENE; ARTICLE; BMAL1 GENE; CIRCADIAN RHYTHM; CONTROLLED STUDY; CPT1C GENE; CRY1 GENE; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION PROFILING; GENE REPRESSION; GENETIC TRANSCRIPTION; HYPOTHALAMUS; OGT GENE; PER2 GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; NERVE CELL; PHOSPHORYLATION;

AGOUTI-RELATED PROTEIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ARNTL TRANSCRIPTION FACTORS; CELL LINE; CIRCADIAN RHYTHM; CLOCK PROTEINS; GENE EXPRESSION REGULATION; GLUCOSE; HYPOTHALAMUS; MICE; NEURONS; PERIOD CIRCADIAN PROTEINS; PHOSPHORYLATION; PYRAZOLES; PYRIMIDINES;

EID: 84958214808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0146969     Document Type: Article

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