Compound C inhibits clonal expansion of preadipocytes by increasing p21 level irrespectively of AMPK inhibition

Archives of Biochemistry and Biophysics

Volumn 479, Issue 1, 2008, Pages 74-81

  Nam, Minwoo ^a   Lee, Woo Hyung ^a   Bae, Eun Ju ^a   Kim, Sang Geon ^a  

^a Tumor Microenvironment Global Core Research Center   (South Korea)

Author keywords

Adipogenesis; AMP activated protein kinase; Compound C; Mitotic clonal expansion; p21; Protein stability

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; COMPOUND C; CYCLIN A; CYCLIN D1; CYCLOHEXIMIDE; DEXAMETHASONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MESSENGER RNA; METFORMIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE B; PROTEIN P21; PROTEIN P27; PYRIMIDINE DERIVATIVE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONE CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENZYME ACTIVATION; ENZYME INHIBITORS; MICE; MITOSIS; PYRAZOLES; PYRIMIDINES; TIME FACTORS;

EID: 53649106018     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2008.07.029     Document Type: Article

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