Mitochondrial protein PGAM5 regulates mitophagic protection against cell necroptosis

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Lu, Wei ^a   Sun, Junhui ^b   Yoon, Jeong Seon ^c   Zhang, Yan ^d   Zheng, Lixin ^a   Murphy, Elizabeth ^b   Mattson, Mark P ^c   Lenardo, Michael J ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL PROTEIN; PROTEIN PGAM5; PROTEIN PINK1; PROTEIN RIP1; PROTEIN RIP3; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; PGAM5 PROTEIN, MOUSE; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; HT 29 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOPHAGY; MOUSE; NECROPTOSIS; NONHUMAN; OXIDATIVE STRESS; PGAM5 GENE; PROTEIN DEPLETION; REGULATORY MECHANISM; REPERFUSION INJURY; ANIMAL; BRAIN; GENETICS; HEART MUSCLE ISCHEMIA; KNOCKOUT MOUSE; METABOLISM; NECROSIS; PHYSIOLOGY;

ANIMALS; BRAIN; MICE; MICE, KNOCKOUT; MITOCHONDRIAL DEGRADATION; MYOCARDIAL ISCHEMIA; NECROSIS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORIC MONOESTER HYDROLASES; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 84958213835     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147792     Document Type: Article

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