Scalable production of a multifunctional protein (TSG-6) that aggregates with itself and the CHO cells that synthesize It

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Kim, Dong Ki ^a   Choi, Hosoon ^a   Nishida, Hidetaka ^b   Oh, Joo Youn ^a   Gregory, Carl ^b   Lee, Ryang Hwa ^c   Yu, Ji Min ^d   Watanabe, Jun ^d   An, Su Yeon ^a   Bartosh, Thomas J ^a   Prockop, Darwin J ^a  

^a SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^b Seoul National University Hospital   (South Korea)

^c Department of Translational Research   (South Korea)

^d SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; HEPARIN; HYALURONIC ACID; PROTEIN TSG 6; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; LIPOPOLYSACCHARIDE; RECOMBINANT PROTEIN; TNFAIP6 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANION EXCHANGE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CHO CELL LINE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESPONSE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; ADULT STEM CELL; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; CRICETULUS; CYTOLOGY; HALF LIFE TIME; HAMSTER; METABOLISM;

ADULT STEM CELLS; ANIMALS; CELL ADHESION MOLECULES; CRICETINAE; CRICETULUS; HALF-LIFE; HUMANS; HYALURONIC ACID; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; RECOMBINANT PROTEINS;

EID: 84958211590     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147553     Document Type: Article

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