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Volumn 63, Issue 4, 2011, Pages 1034-1043

TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; COLONY STIMULATING FACTOR 1; INTERLEUKIN 1; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR STIMULATED GENE 6 PROTEIN; UNCLASSIFIED DRUG;

EID: 79953673228     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30201     Document Type: Article
Times cited : (44)

References (45)
  • 1
    • 0026597436 scopus 로고
    • A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44
    • Lee TH, Wisniewski HG, Vilcek J. A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J Cell Biol 1992;116:545-57.
    • (1992) J Cell Biol , vol.116 , pp. 545-557
    • Lee, T.H.1    Wisniewski, H.G.2    Vilcek, J.3
  • 2
    • 0037769541 scopus 로고    scopus 로고
    • TSG-6: A multifunctional protein associated with inflammation
    • DOI 10.1242/jcs.00407
    • Milner CM, Day AJ. TSG-6: a multifunctional protein associated with inflammation. J Cell Sci 2003;116:1863-73. (Pubitemid 36622285)
    • (2003) Journal of Cell Science , vol.116 , Issue.10 , pp. 1863-1873
    • Milner, C.M.1    Day, A.J.2
  • 5
    • 54449097293 scopus 로고    scopus 로고
    • TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation
    • Mahoney DJ, Mikecz K, Ali T, Mabilleau G, Benayahu D, Plaas A, et al. TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation. J Biol Chem 2008; 283:25952-62.
    • (2008) J Biol Chem , vol.283 , pp. 25952-25962
    • Mahoney, D.J.1    Mikecz, K.2    Ali, T.3    Mabilleau, G.4    Benayahu, D.5    Plaas, A.6
  • 6
    • 22844433324 scopus 로고    scopus 로고
    • Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: Implications for the inhibition of plasmin in extracellular matrix microenvironments
    • Mahoney DJ, Mulloy B, Forster MJ, Blundell CD, Fries E, Milner CM, et al. Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments. J Biol Chem 2005;280:27044-55.
    • (2005) J Biol Chem , vol.280 , pp. 27044-2755
    • Mahoney, D.J.1    Mulloy, B.2    Forster, M.J.3    Blundell, C.D.4    Fries, E.5    Milner, C.M.6
  • 7
    • 0030572693 scopus 로고    scopus 로고
    • Solution structure of the link module: A hyaluronan-binding domain involved in extracellular matrix stability and cell migration
    • DOI 10.1016/S0092-8674(00)80151-8
    • Kohda D, Morton CJ, Parkar AA, Hatanaka H, Inagaki FM, Campbell ID, et al. Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration. Cell 1996;86:767-75. (Pubitemid 26303445)
    • (1996) Cell , vol.86 , Issue.5 , pp. 767-775
    • Kohda, D.1    Morton, C.J.2    Parkar, A.A.3    Hatanaka, H.4    Inagaki, F.M.5    Campbell, I.D.6    Day, A.J.7
  • 9
    • 0035128852 scopus 로고    scopus 로고
    • Up-regulation and differential expression of the hyaluronanbinding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis
    • Bayliss MT, Howat SL, Dudhia J, Murphy JM, Barry FP, Edwards JC, et al. Up-regulation and differential expression of the hyaluronanbinding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis. Osteoarthritis Cartilage 2000;9:42-8.
    • (2000) Osteoarthritis Cartilage , vol.9 , pp. 42-48
    • Bayliss, M.T.1    Howat, S.L.2    Dudhia, J.3    Murphy, J.M.4    Barry, F.P.5    Edwards, J.C.6
  • 10
    • 0029936595 scopus 로고    scopus 로고
    • TSG-6 expression in human articular chondrocytes: Possible implications in joint inflammation and cartilage degradation
    • DOI 10.1002/art.1780390403
    • Maier R, Wisniewski HG, Vilcek J, Lotz M. TSG-6 expression in human articular chondrocytes: possible implications in joint inflammation and cartilage degradation. Arthritis Rheum 1996;39: 552-9. (Pubitemid 26119638)
    • (1996) Arthritis and Rheumatism , vol.39 , Issue.4 , pp. 552-559
    • Maier, R.1    Wisniewski, H.-G.2    Vilcek, J.3    Lotz, M.4
  • 12
    • 0242304091 scopus 로고    scopus 로고
    • Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: Upregulation of hyaluronan-binding protein TSG-6
    • Kehlen A, Pachnio A, Thiele K, Langner J. Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6. Arthritis Res Ther 2003;5:R186-92.
    • (2003) Arthritis Res Ther , vol.5
    • Kehlen, A.1    Pachnio, A.2    Thiele, K.3    Langner, J.4
  • 13
    • 0035157815 scopus 로고    scopus 로고
    • Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-α-stimulated gene-6) in murine models of experimental arthritis
    • Bardos T, Kamath RV, Mikecz K, Glant TT. Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-α- stimulated gene-6) in murine models of experimental arthritis. Am J Pathol 2001;159:1711-21. (Pubitemid 33062514)
    • (2001) American Journal of Pathology , vol.159 , Issue.5 , pp. 1711-1721
    • Bardos, T.1    Kamath, R.V.2    Mikecz, K.3    Glant, T.T.4
  • 15
    • 0036676099 scopus 로고    scopus 로고
    • Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor α-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigeninduced arthritis
    • Glant TT, Kamath RV, Bardos T, Gal I, Szanto S, Murad YM, et al. Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor α-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigeninduced arthritis. Arthritis Rheum 2002;46:2207-18.
    • (2002) Arthritis Rheum , vol.46 , pp. 2207-2218
    • Glant, T.T.1    Kamath, R.V.2    Bardos, T.3    Gal, I.4    Szanto, S.5    Murad, Y.M.6
  • 16
    • 4444220196 scopus 로고    scopus 로고
    • Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice
    • DOI 10.1002/art.20655
    • Szanto S, Bardos T, Gal I, Glant TT, Mikecz K. Enhanced neutrophil extravasation and rapid progression of proteoglycaninduced arthritis in TSG-6-knockout mice. Arthritis Rheum 2004; 50:3012-22. (Pubitemid 39209541)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 3012-3022
    • Szanto, S.1    Bardos, T.2    Gal, I.3    Glant, T.T.4    Mikecz, K.5
  • 17
    • 0034538216 scopus 로고    scopus 로고
    • Amelioration of collagen-induced arthritis in DBA/1J mice by recombinant TSG-6, a tumor necrosis factor/interleukin-1-inducible protein
    • DOI 10.1002/1529-0131(200012)43:12<2668::AID-ANR6>3.0.CO;2-E
    • Mindrescu C, Thorbecke GJ, Klein MJ, Vilcek J, Wisniewski HG. Amelioration of collagen-induced arthritis in DBA/1J mice by recombinant TSG-6, a tumor necrosis factor/interleukin-1-inducible protein. Arthritis Rheum 2000;43:2668-77. (Pubitemid 32001732)
    • (2000) Arthritis and Rheumatism , vol.43 , Issue.12 , pp. 2668-2677
    • Mindrescu, C.1    Thorbecke, G.J.2    Klein, M.J.3    Vilek, J.4    Wisniewski, H.-G.5
  • 18
    • 0030056876 scopus 로고    scopus 로고
    • TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-α-inhibitor and exerts a strong anti-inflammatory effect in vivo
    • Wisniewski HG, Hua JC, Poppers DM, Naime D, Vilcek J, Cronstein BN. TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-α-inhibitor and exerts a strong anti-inflammatory effect in vivo. J Immunol 1996;156:1609-15.
    • (1996) J Immunol , vol.156 , pp. 1609-1615
    • Wisniewski, H.G.1    Hua, J.C.2    Poppers, D.M.3    Naime, D.4    Vilcek, J.5    Cronstein, B.N.6
  • 20
    • 10244226614 scopus 로고    scopus 로고
    • Inhibitory effects of TSG-6 link module on leukocyte-endothelial cell interactions in vitro and in vivo
    • DOI 10.1080/10739680490503438
    • Cao TV, La M, Getting SJ, Day AJ, Perreti M. Inhibitory effects of TSG-6 Link module on leukocyte-endothelial cell interactions in vitro and in vivo. Microcirculation 2004;11:615-24. (Pubitemid 39618633)
    • (2004) Microcirculation , vol.11 , Issue.7 , pp. 615-624
    • Cao, T.V.1    La, M.2    Getting, S.J.3    Day, A.J.4    Perretti, M.5
  • 21
    • 79953704873 scopus 로고    scopus 로고
    • Athanasou NA. Diseases of articular tissues
    • London: Edward Arnold
    • Athanasou NA. Diseases of articular tissues. In: Pathological basis of orthopaedic and rheumatic disease. London: Edward Arnold; 2001. p. 155-201.
    • (2001) Pathological Basis of Orthopaedic and Rheumatic Disease , pp. 155-201
  • 23
    • 0030221293 scopus 로고    scopus 로고
    • Overexpression, purification, and refolding of link module from human TSG-6 in Escherichia coli: Effect of temperature, media, and mutagenesis on lysine misincorporation at arginine AGA codons
    • DOI 10.1006/prep.1996.0068
    • Day AJ, Aplin RT, Willis AC. Overexpression, purification, and refolding of link module from human TSG-6 in Escherichia coli: effect of temperature, media, and mutagenesis on lysine misincorporation at arginine AGA codons. Protein Expr Purif 1996;8:1-16. (Pubitemid 26326208)
    • (1996) Protein Expression and Purification , vol.8 , Issue.1 , pp. 1-16
    • Day, A.J.1    Aplin, R.T.2    Willis, A.C.3
  • 24
    • 0031127761 scopus 로고    scopus 로고
    • Method for quantitative refolding of the link module from human TSG-6
    • DOI 10.1006/prep.1996.0694
    • Kahmann JD, Koruth R, Day AJ. Method for quantitative refolding of the link module from human TSG-6. Protein Expr Purif 1997;9:315-8. (Pubitemid 27210699)
    • (1997) Protein Expression and Purification , vol.9 , Issue.3 , pp. 315-318
    • Kahmann, J.D.1    Koruth, R.2    Day, A.J.3
  • 25
    • 0037135550 scopus 로고    scopus 로고
    • Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6
    • DOI 10.1074/jbc.M201068200
    • Lesley J, English NM, Gal I, Mikecz K, Day AJ, Hyman R. Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6. J Biol Chem 2002;277:26600-8. (Pubitemid 34967158)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26600-26608
    • Lesley, J.1    English, N.M.2    Gal, I.3    Mikecz, K.4    Day, A.J.5    Hyman, R.6
  • 30
    • 70350510860 scopus 로고    scopus 로고
    • IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-α antibody: A novel mechanism of osteoclastogenesis by IL-17
    • Yago T, Nanke Y, Ichikawa N, Kobashigawa T, Mogi M, Kamatani N, et al. IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-α antibody: a novel mechanism of osteoclastogenesis by IL-17. J Cell Biochem 2009;108:947-55.
    • (2009) J Cell Biochem , vol.108 , pp. 947-955
    • Yago, T.1    Nanke, Y.2    Ichikawa, N.3    Kobashigawa, T.4    Mogi, M.5    Kamatani, N.6
  • 31
    • 0036771556 scopus 로고    scopus 로고
    • Proinflammatory cytokine (TNFα/IL-Iα) induction of human osteoclast formation
    • DOI 10.1002/path.1190
    • Kudo O, Fujikawa Y, Itonaga I, Sabokbar A, Torisu T, Athanasou NA. Proinflammatory cytokine (TNFα/IL-1α) induction of human osteoclast formation. J Pathol 2002;198:220-7. (Pubitemid 35243880)
    • (2002) Journal of Pathology , vol.198 , Issue.2 , pp. 220-227
    • Kudo, O.1    Fujikawa, Y.2    Itonaga, I.3    Sabokbar, A.4    Torisu, T.5    Athanasou, N.A.6
  • 32
    • 0037265995 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism
    • DOI 10.1016/S8756-3282(02)00915-8
    • Kudo O, Sabokbar A, Pocock A, Itonaga I, Fujikawa Y, Athanasou NA. Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone 2003;32:1-7. (Pubitemid 36173806)
    • (2003) Bone , vol.32 , Issue.1 , pp. 1-7
    • Kudo, O.1    Sabokbar, A.2    Pocock, A.3    Itonaga, I.4    Fujikawa, Y.5    Athanasou, N.A.6
  • 34
    • 77950640257 scopus 로고    scopus 로고
    • Functions of nuclear factor κb in bone
    • Boyce BF, Yao Z, Xing L. Functions of nuclear factor κB in bone. Ann N Y Acad Sci 2010;1192:367-75.
    • (2010) Ann N y Acad Sci , vol.1192 , pp. 367-375
    • Boyce, B.F.1    Yao, Z.2    Xing, L.3
  • 38
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    • DOI 10.1016/S8756-3282(99)00162-3, PII S8756328299001623
    • Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S. Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 1999;25:255-9. (Pubitemid 29406050)
    • (1999) Bone , vol.25 , Issue.3 , pp. 255-259
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5    Khosla, S.6
  • 39
    • 49449100184 scopus 로고    scopus 로고
    • Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast- mediated pathologic bone resorption
    • Tunyogi-Csapo M, Kis-Toth K, Radacs M, Farkas B, Jacobs JJ, Finnegan A, et al. Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast- mediated pathologic bone resorption. Arthritis Rheum 2008; 58:2397-408.
    • (2008) Arthritis Rheum , vol.58 , pp. 2397-2408
    • Tunyogi-Csapo, M.1    Kis-Toth, K.2    Radacs, M.3    Farkas, B.4    Jacobs, J.J.5    Finnegan, A.6
  • 40
    • 0032502353 scopus 로고    scopus 로고
    • Activation of NF-κB is involved in the survival of osteoclasts promoted by interleukin-1
    • DOI 10.1074/jbc.273.15.8799
    • Jimi E, Nakamura I, Ikebe T, Akiyama S, Takahashi N, Suda T. Activation of NF-κB is involved in the survival of osteoclasts promoted by interleukin-1. J Biol Chem 1998;273:8799-805. (Pubitemid 28176159)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.15 , pp. 8799-8805
    • Jimi, E.1    Nakamura, I.2    Ikebe, T.3    Akiyama, S.4    Takahashi, N.5    Suda, T.6
  • 41
    • 0034677177 scopus 로고    scopus 로고
    • Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKLRANK interaction
    • Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, et al. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKLRANK interaction. J Exp Med 2000;191:275-86.
    • (2000) J Exp Med , vol.191 , pp. 275-286
    • Kobayashi, K.1    Takahashi, N.2    Jimi, E.3    Udagawa, N.4    Takami, M.5    Kotake, S.6
  • 42
  • 43
    • 67650299732 scopus 로고    scopus 로고
    • Osteoclasts have multiple roles in bone in addition to bone resorption
    • Boyce BF, Yao Z, Xing L. Osteoclasts have multiple roles in bone in addition to bone resorption. Crit Rev Eukaryot Gene Expr 2009:19;171-80.
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 171-180
    • Boyce, B.F.1    Yao, Z.2    Xing, L.3
  • 44
    • 70349705616 scopus 로고    scopus 로고
    • NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism
    • Yao Z, Xing L, Boyce BF. NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism. J Clin Invest 2009;119:3024-34.
    • (2009) J Clin Invest , vol.119 , pp. 3024-3034
    • Yao, Z.1    Xing, L.2    Boyce, B.F.3
  • 45
    • 17244364098 scopus 로고    scopus 로고
    • Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study
    • DOI 10.1002/art.20982
    • Smolen JS, Han C, Bala M, Maini RN, Kalden JR, van der Heijde D, et al, for the ATTRACT Study Group. Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: a detailed subanalysis of data from the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis With Concomitant Therapy study. Arthritis Rheum 2005;52:1020-30. (Pubitemid 40530107)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.4 , pp. 1020-1030
    • Smolen, J.S.1    Han, C.2    Bala, M.3    Maini, R.N.4    Kalden, J.R.5    Van Der Heijde, D.6    Breedveld, F.C.7    Furst, D.E.8    Lipsky, P.E.9


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