A refined model for the TSG-6 link module in complex with hyaluronan: Use of defined oligosaccharides to probe structure and function

Journal of Biological Chemistry

Volumn 289, Issue 9, 2014, Pages 5619-5634

  Higman, Victoria A ^a   Briggs, David C ^b,c   Mahoney, David J ^a   Blundell, Charles D ^c   Sattelle, Benedict M ^c   Dyer, Douglas P ^b,c   Green, Dixy E ^d   DeAngelis, Paul L ^d   Almond, Andrew ^c   Milner, Caroline M ^c   Day, Anthony J ^b,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

D-GLUCURONIC ACID; EXTRACELLULAR MATRICES; HIGH MOLECULAR WEIGHT; HYBRID OLIGOMERS; INFLAMMATORY PROCESS; IONIC INTERACTION; N-ACETYL-D-GLUCOSAMINE; PROBE STRUCTURES;

AMINO ACIDS; CHAINS; GLUCOSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOSACCHARIDES; PATHOLOGY; PROTEINS;

HYALURONIC ACID;

CARBON 13; CHONDROITIN; GLUCURONIC ACID; HERMES ANTIGEN; HISTIDINE; HYALURONIC ACID; HYALURONIC ACID DERIVATIVE; LYSINE; OLIGOMER; PEPTIDES AND PROTEINS; PROTEIN TSG 6; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOHYDRATE ANALYSIS; CHEMICAL MODIFICATION; COMPLEX FORMATION; CONTROLLED STUDY; INFLAMMATION; ISOTOPE LABELING; MOLECULAR INTERACTION; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; THERMODYNAMICS;

CHONDROITIN; DEFINED SUGARS; HYALURONATE; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MODELING; NMR; TSG-6;

ANTIGENS, CD44; CELL ADHESION MOLECULES; FEMALE; HUMANS; HYALURONIC ACID; INFLAMMATION; MODELS, MOLECULAR; OLIGOSACCHARIDES; OVULATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84896810282     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.542357     Document Type: Article

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