Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating

Cell

Volumn 164, Issue 4, 2016, Pages 747-756

  Matthies, Doreen ^a   Dalmas, Olivier ^b   Borgnia, Mario J ^a   Dominik, Pawel K ^b   Merk, Alan ^a   Rao, Prashant ^a   Reddy, Bharat G ^b   Islam, Shahidul ^b   Bartesaghi, Alberto ^a   Perozo, Eduardo ^b   Subramaniam, Sriram ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

asymmetry; conformational change; direct electron detector; ion channel; membrane protein structure; single particle cryo electron microscopy

Indexed keywords

ION CHANNEL; MAGNESIUM CHANNEL CORA; MAGNESIUM ION; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CATION TRANSPORT PROTEIN; MAGNESIUM;

ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; MOTION; PRIORITY JOURNAL; PROKARYOTE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR MODEL; THERMOTOGA MARITIMA; ULTRASTRUCTURE;

BACTERIAL PROTEINS; CATION TRANSPORT PROTEINS; CRYOELECTRON MICROSCOPY; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; THERMOTOGA MARITIMA;

EID: 84958191427     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.12.055     Document Type: Article

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