Mechanotransduction in cancer

Current Opinion in Chemical Engineering

Volumn 11, Issue , 2016, Pages 77-84

  Chin, LiKang ^a,b   Xia, Yuntao ^a   Discher, Dennis E ^a   Janmey, Paul A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b TOKUSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DISEASES; STIFFNESS; STIFFNESS MATRIX; TISSUE;

ANGIOGENESIS; EXTRACELLULAR MATRICES; MECHANICAL ENVIRONMENT; MECHANOTRANSDUCTION; NORMAL CONDITION; SIGNALING MECHANISMS; STROMAL CELLS; TISSUE STIFFNESS;

CELL SIGNALING;

EID: 84958177786     PISSN: None     EISSN: 22113398     Source Type: Journal    
DOI: 10.1016/j.coche.2016.01.011     Document Type: Review

References (64)

1. K.J. Streitberger, M. Reiss-Zimmermann, F.B. Freimann, S. Bayerl, J. Guo, F. Arlt, J. Wuerfel, J. Braun, K.T. Hoffmann, and I. Sack High-resolution mechanical imaging of glioblastoma by multifrequency magnetic resonance elastography PLOS ONE 9 2014 e110588
2. J.T. Poterucha, J.N. Johnson, M.Y. Qureshi, P.W. O'Leary, P.S. Kamath, R.J. Lennon, C.R. Bonnichsen, P.M. Young, S.K. Venkatesh, R.L. Ehman, and et al. Magnetic resonance elastography: a novel technique for the detection of hepatic fibrosis and hepatocellular carcinoma after the Fontan operation Mayo Clin Proc 90 2015 882 894
3. J.A. Weis, K.M. Flint, V. Sanchez, T.E. Yankeelov, and M.I. Miga Assessing the accuracy and reproducibility of modality independent elastography in a murine model of breast cancer J Med Imaging (Bellingham) 2 2015 036001
4. U. Zaleska-Dorobisz, K. Kaczorowski, A. Pawlus, A. Puchalska, and M. Inglot Ultrasound elastography - review of techniques and its clinical applications Adv Clin Exp Med 23 2014 645 655
5. H.B. Wang, M. Dembo, and Y.L. Wang Substrate flexibility regulates growth and apoptosis of normal but not transformed cells Am J Physiol Cell Physiol 279 2000 C1345 C1350
6. H.H. Lin, H.K. Lin, I.H. Lin, Y.W. Chiou, H.W. Chen, C.Y. Liu, H.I. Harn, W.T. Chiu, Y.K. Wang, M.R. Shen, and et al. Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing Oncotarget 6 2015 20946 20958
7. S.Y. Wong, T.A. Ulrich, L.P. Deleyrolle, J.L. MacKay, J.M. Lin, R.T. Martuscello, M.A. Jundi, B.A. Reynolds, and S. Kumar Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion Cancer Res 75 2015 1113 1122
8. W.A. Lam, L. Cao, V. Umesh, A.J. Keung, S. Sen, and S. Kumar Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression Mol Cancer 9 2010
9. J.L. Leight, M.A. Wozniak, S. Chen, M.L. Lynch, and C.S. Chen Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition Mol Biol Cell 23 2012 781 791
10. K. Zhang, C.A. Corsa, S.M. Ponik, J.L. Prior, D. Piwnica-Worms, K.W. Eliceiri, P.J. Keely, and G.D. Longmore The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis Nat Cell Biol 15 2013 677 687
11. S. Nasrollahi, and A. Pathak Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matrices Sci Rep 6 2016 18831
12. D.J. McGrail, Q.M. Kieu, and M.R. Dawson The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho-ROCK pathway J Cell Sci 127 2014 2621 2626
13. K. Lee, Q.K. Chen, C. Lui, M.A. Cichon, D.C. Radisky, and C.M. Nelson Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition Mol Biol Cell 23 2012 4097 4108
14. E. Kniazeva, and A.J. Putnam Endothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D Am J Physiol Cell Physiol 297 2009 C179 C187
15. Y. Dong, X. Xie, Z. Wang, C. Hu, Q. Zheng, Y. Wang, R. Chen, T. Xue, J. Chen, D. Gao, and et al. Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin beta1 Biochem Biophys Res Commun 444 2014 427 432
16. F. Bordeleau, J.P. Califano, Y.L. Negron Abril, B.N. Mason, D.J. LaValley, S.J. Shin, R.S. Weiss, and C.A. Reinhart-King Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors Proc Natl Acad Sci U S A 112 2015 8314 8319
17. K.R. Levental, H. Yu, L. Kass, J.N. Lakins, M. Egeblad, J.T. Erler, S.F. Fong, K. Csiszar, A. Giaccia, W. Weninger, and et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling Cell 139 2009 891 906
18. G. Weder, M.C. Hendriks-Balk, R. Smajda, D. Rimoldi, M. Liley, H. Heinzelmann, A. Meister, and A. Mariotti Increased plasticity of the stiffness of melanoma cells correlates with their acquisition of metastatic properties Nanomedicine 10 2014 141 148
19. X. Wang, J. Wang, Y. Liu, H. Zong, X. Che, W. Zheng, F. Chen, Z. Zhu, D. Yang, and X. Song Alterations in mechanical properties are associated with prostate cancer progression Med Oncol 31 2014 876
20. K.M. Stroka, and K. Konstantopoulos Physical biology in cancer. 4. Physical cues guide tumor cell adhesion and migration Am J Physiol Cell Physiol 306 2014 C98 C109
21. X. Tang, T.B. Kuhlenschmidt, Q. Li, S. Ali, S. Lezmi, H. Chen, M. Pires-Alves, W.W. Laegreid, T.A. Saif, and M.S. Kuhlenschmidt A mechanically-induced colon cancer cell population shows increased metastatic potential Mol Cancer 13 2014 131
22. Y. Tan, A. Tajik, J. Chen, Q. Jia, F. Chowdhury, L. Wang, J. Chen, S. Zhang, Y. Hong, H. Yi, and et al. Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression Nat Commun 5 2014 4619
23. I. Acerbi, L. Cassereau, I. Dean, Q. Shi, A. Au, C. Park, Y.Y. Chen, J. Liphardt, E.S. Hwang, and V.M. Weaver Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration Integr Biol (Camb) 7 2015 1120 1134
24. Z. Zhou, M. Qutaish, Z. Han, R.M. Schur, Y. Liu, D.L. Wilson, and Z.R. Lu MRI detection of breast cancer micrometastases with a fibronectin-targeting contrast agent Nat Commun 6 2015 7984
25. B. Fernandez-Garcia, N. Eiro, L. Marin, S. Gonzalez-Reyes, L.O. Gonzalez, M.L. Lamelas, and F.J. Vizoso Expression and prognostic significance of fibronectin and matrix metalloproteases in breast cancer metastasis Histopathology 64 2014 512 522
26. S. Suer, H. Baloglu, Z. Gungor, H. Sonmez, and E. Kokoglu The distribution of tissue fibronectin and sialic acid in human breast cancer Cancer Biochem Biophys 16 1998 63 70
27. E.S. Yao, H. Zhang, Y.Y. Chen, B. Lee, K. Chew, D. Moore, and C. Park Increased beta1 integrin is associated with decreased survival in invasive breast cancer Cancer Res 67 2007 659 664
28. K. Wang, R.C. Andresen Eguiluz, F. Wu, B.R. Seo, C. Fischbach, and D. Gourdon Stiffening and unfolding of early deposited-fibronectin increase proangiogenic factor secretion by breast cancer-associated stromal cells Biomaterials 54 2015 63 71
29. M. Rodriguez-Teja, J.H. Gronau, C. Breit, Y.Z. Zhang, A. Minamidate, M.P. Caley, A. McCarthy, T.R. Cox, J.T. Erler, L. Gaughan, and et al. AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival J Pathol 235 2015 581 592
30. T.J. Kowal, and M.M. Falk Primary cilia found on HeLa and other cancer cells Cell Biol Int 39 2015 1341 1347
31. A.N. Gargalionis, P. Korkolopoulou, E. Farmaki, C. Piperi, G. Dalagiorgou, C. Adamopoulos, G. Levidou, A. Saetta, P. Fragkou, P. Tsioli, and et al. Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer Int J Cancer 136 2015 1515 1527
32. M.G. Rubashkin, L. Cassereau, R. Bainer, C.C. DuFort, Y. Yui, G. Ou, M.J. Paszek, M.W. Davidson, Y.Y. Chen, and V.M. Weaver Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate Cancer Res 74 2014 4597 4611
33. Y. Yuan, W. Zhong, G. Ma, B. Zhang, and H. Tian Yes-associated protein regulates the growth of human non-small cell lung cancer in response to matrix stiffness Mol Med Rep 11 2015 4267 4272
34. S.C. Wei, L. Fattet, J.H. Tsai, Y. Guo, V.H. Pai, H.E. Majeski, A.C. Chen, R.L. Sah, S.S. Taylor, A.J. Engler, and et al. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway Nat Cell Biol 17 2015 678 688
35. S.P. Zustiak, S. Dadhwal, C. Medina, S. Steczina, Y. Chehreghanianzabi, A. Ashraf, and P. Asuri Three-dimensional matrix stiffness and adhesive ligands affect cancer cell response to toxins Biotechnol Bioeng 2015
36. E. Jabbari, S.K. Sarvestani, L. Daneshian, and S. Moeinzadeh Optimum 3D matrix stiffness for maintenance of cancer stem cells is dependent on tissue origin of cancer cells PLOS ONE 10 2015 e0132377
37. Y.I. Shen, H.E. Abaci, Y. Krupsi, L.C. Weng, J.A. Burdick, and S. Gerecht Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting Biomater Sci 2 2014 655 665
38. B.P. Toole Hyaluronan: from extracellular glue to pericellular cue Nat Rev Cancer 4 2004 528 539
39. M.P. Ween, M.K. Oehler, and C. Ricciardelli Role of versican, hyaluronan and CD44 in ovarian cancer metastasis Int J Mol Sci 12 2011 1009 1029
40. R. Pirinen, R. Tammi, M. Tammi, P. Hirvikoski, J.J. Parkkinen, R. Johansson, J. Bohm, S. Hollmen, and V.M. Kosma Prognostic value of hyaluronan expression in non-small-cell lung cancer: increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma Int J Cancer 95 2001 12 17
41. J.T. Posey, M.S. Soloway, S. Ekici, M. Sofer, F. Civantos, R.C. Duncan, and V.B. Lokeshwar Evaluation of the prognostic potential of hyaluronic acid and hyaluronidase (HYAL1) for prostate cancer Cancer Res 63 2003 2638 2644
42. P. Lipponen, S. Aaltomaa, R. Tammi, M. Tammi, U. Agren, and V.M. Kosma High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer Eur J Cancer 37 2001 849 856
43. K. Ropponen, M. Tammi, J. Parkkinen, M. Eskelinen, R. Tammi, P. Lipponen, U. Agren, E. Alhava, and V.M. Kosma Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer Cancer Res 58 1998 342 347
44. L.P. Setala, M.I. Tammi, R.H. Tammi, M.J. Eskelinen, P.K. Lipponen, U.M. Agren, J. Parkkinen, E.M. Alhava, and V.M. Kosma Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate Br J Cancer 79 1999 1133 1138
45. V.B. Lokeshwar, G.L. Schroeder, M.G. Selzer, S.H. Hautmann, J.T. Posey, R.C. Duncan, R. Watson, L. Rose, S. Markowitz, and M.S. Soloway Bladder tumor markers for monitoring recurrence and screening comparison of hyaluronic acid-hyaluronidase and BTA-Stat tests Cancer 95 2002 61 72
46. B. Delpech, B. Chevallier, N. Reinhardt, J.P. Julien, C. Duval, C. Maingonnat, P. Bastit, and B. Asselain Serum hyaluronan (hyaluronic acid) in breast cancer patients Int J Cancer 46 1990 388 390
47. E.J. Franzmann, G.L. Schroeder, W.J. Goodwin, D.T. Weed, P. Fisher, and V.B. Lokeshwar Expression of tumor markers hyaluronic acid and hyaluronidase (HYAL1) in head and neck tumors Int J Cancer 106 2003 438 445
48. Y. Kim, and S. Kumar CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility Mol Cancer Res 12 2014 1416 1429
49. A. Chopra, M.E. Murray, F.J. Byfield, M.G. Mendez, R. Halleluyan, D.J. Restle, D. Raz-Ben Aroush, P.A. Galie, K. Pogoda, R. Bucki, and et al. Augmentation of integrin-mediated mechanotransduction by hyaluronic acid Biomaterials 35 2014 71 82
50. K. Nagayama, Y. Hamaji, Y. Sato, and T. Matsumoto Mechanical trapping of the nucleus on micropillared surfaces inhibits the proliferation of vascular smooth muscle cells but not cervical cancer HeLa cells J Biomech 48 2015 1796 1803
51. L.M. Lee, and A.P. Liu A microfluidic pipette array for mechanophenotyping of cancer cells and mechanical gating of mechanosensitive channels Lab Chip 15 2015 264 273
52. H.H. Song, K.M. Park, and S. Gerecht Hydrogels to model 3D in vitro microenvironment of tumor vascularization Adv Drug Deliv Rev 79-80 2014 19 29
53. J.S. Jeon, S. Bersini, M. Gilardi, G. Dubini, J.L. Charest, M. Moretti, and R.D. Kamm Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation Proc Natl Acad Sci U S A 112 2015 214 219
54. S.P. Carey, A. Rahman, C.M. Kraning-Rush, B. Romero, S. Somasegar, O.M. Torre, R.M. Williams, and C.A. Reinhart-King Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks Am J Physiol Cell Physiol 308 2015 C436 C447
55. N. Nijenhuis, D. Mizuno, J.A. Spaan, and C.F. Schmidt High-resolution microrheology in the pericellular matrix of prostate cancer cells J R Soc Interface 9 2012 1733 1744
56. M.F. Berry, A.J. Engler, Y.J. Woo, T.J. Pirolli, L.T. Bish, V. Jayasankar, K.J. Morine, T.J. Gardner, D.E. Discher, and H.L. Sweeney Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance Am J Physiol Heart Circ Physiol 290 2006 H2196 H2203
57. P.C. Dingal, A.M. Bradshaw, S. Cho, M. Raab, A. Buxboim, J. Swift, and D.E. Discher Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor Nat Mater 14 2015 951 960
58. R. Kramann, R.K. Schneider, D.P. DiRocco, F. Machado, S. Fleig, P.A. Bondzie, J.M. Henderson, B.L. Ebert, and B.D. Humphreys Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis Cell Stem Cell 16 2015 51 66
59. C.J. Mann, E. Perdiguero, Y. Kharraz, S. Aguilar, P. Pessina, A.L. Serrano, and P. Munoz-Canoves Aberrant repair and fibrosis development in skeletal muscle Skelet Muscle 1 2011 21
60. L.R. Smith, and E.R. Barton Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice Am J Physiol Cell Physiol 306 2014 C889 C898
61. P.J. Wipff, D.B. Rifkin, J.J. Meister, and B. Hinz Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix J Cell Biol 179 2007 1311 1323
62. A.L. Olsen, S.A. Bloomer, E.P. Chan, M.D. Gaca, P.C. Georges, B. Sackey, M. Uemura, P.A. Janmey, and R.G. Wells Hepatic stellate cells require a stiff environment for myofibroblastic differentiation Am J Physiol Gastrointest Liver Physiol 301 2011 G110 G118
63. G.L. Davis, J. Dempster, J.D. Meler, D.W. Orr, M.W. Walberg, B. Brown, B.D. Berger, J.K. O'Connor, and R.M. Goldstein Hepatocellular carcinoma: management of an increasingly common problem Proc (Bayl Univ Med Cent) 21 2008 266 280
64. F. Rehfeldt, A.E. Brown, M. Raab, S. Cai, A.L. Zajac, A. Zemel, and D.E. Discher Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells Integr Biol (Camb) 4 2012 422 430