A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation

Cell Reports

Volumn 14, Issue 5, 2016, Pages 1000-1009

  Iwase, Shigeki ^a,b   Brookes, Emily ^a,g   Agarwal, Saurabh ^b   Badeaux, Aimee I ^a   Ito, Hikaru ^c   Vallianatos, Christina N ^b   Tomassy, Giulio Srubek ^d   Kasza, Tomas ^b   Lin, Grace ^e   Thompson, Andrew ^a   Gu, Lei ^a   Kwan, Kenneth Y ^e   Chen, Chinfei ^a   Sartor, Maureen A ^b   Egan, Brian ^f   Xu, Jun ^c   Shi, Yang ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d Harvard University   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f Active Motif Inc   (United States)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; TRANSCRIPTOME; HISTONE; KDM5C PROTEIN, MOUSE; LYSINE; N DEMETHYLASE;

ADULT; AGGRESSION; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISOCIAL PERSONALITY DISORDER; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CPG ISLAND; DENDRITIC CELL; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; HISTONE METHYLATION; KDM5C GENE; MALE; MOUSE; NERVE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; X LINKED MENTAL RETARDATION; ANIMAL; BRAIN; DEFICIENCY; DENDRITIC SPINE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; INTELLECTUAL IMPAIRMENT; KNOCKOUT MOUSE; MEMORY; METABOLISM; METHYLATION; PATHOLOGY; SOCIAL BEHAVIOR; X CHROMOSOMAL INHERITANCE;

AGGRESSION; ANIMALS; BRAIN; CPG ISLANDS; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENES, X-LINKED; HISTONES; INTELLECTUAL DISABILITY; LYSINE; MEMORY; METHYLATION; MICE, KNOCKOUT; OXIDOREDUCTASES, N-DEMETHYLATING; PROMOTER REGIONS, GENETIC; SOCIAL BEHAVIOR; TRANSCRIPTION, GENETIC;

EID: 84957977678     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.091     Document Type: Article

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