메뉴 건너뛰기




Volumn 387, Issue , 2017, Pages 114-120

Animal models of colorectal cancer with liver metastasis

Author keywords

Colorectal cancer; Genetically engineered mouse model; Liver metastasis; Mouse model; Orthotopic model; Xenografts

Indexed keywords

CANCER MODEL; COLORECTAL CANCER; GENE MUTATION; GENETICALLY ENGINEERED MOUSE STRAIN; HISTOPATHOLOGY; LIVER METASTASIS; METASTASIS POTENTIAL; MOLECULAR IMAGING; NOD SCID GAMMA MOUSE; NOD SCID MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOLOGICAL PARAMETERS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAG1-/- MOUSE; SCID BEIGE MOUSE; SCID MOUSE; SHORT SURVEY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; X-RAY COMPUTED TOMOGRAPHY; ANIMAL; COLORECTAL TUMOR; DISEASE MODEL; HUMAN; LIVER TUMOR; PATHOLOGY; SECONDARY;

EID: 84957922197     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2016.01.048     Document Type: Review
Times cited : (53)

References (86)
  • 1
    • 84896109367 scopus 로고    scopus 로고
    • DPYD, TYMS, TYMP, TK1, and TK2 genetic expressions as response markers in locally advanced rectal cancer patients treated with fluoropyrimidine-based chemoradiotherapy
    • [1] Huang, M.Y., et al. DPYD, TYMS, TYMP, TK1, and TK2 genetic expressions as response markers in locally advanced rectal cancer patients treated with fluoropyrimidine-based chemoradiotherapy. Biomed Res. Int, 2013, 2013, 931028.
    • (2013) Biomed Res. Int , vol.2013 , pp. 931028
    • Huang, M.Y.1
  • 2
    • 84858693012 scopus 로고    scopus 로고
    • Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis
    • [2] Zhang, Z.J., et al. Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis. Diabetes Care 34:10 (2011), 2323–2328.
    • (2011) Diabetes Care , vol.34 , Issue.10 , pp. 2323-2328
    • Zhang, Z.J.1
  • 3
    • 84901366691 scopus 로고    scopus 로고
    • Use of metformin alone is not associated with survival outcomes of colorectal cancer cell but AMPK activator AICAR sensitizes anticancer effect of 5-fluorouracil through AMPK activation
    • [3] Sui, X., et al. Use of metformin alone is not associated with survival outcomes of colorectal cancer cell but AMPK activator AICAR sensitizes anticancer effect of 5-fluorouracil through AMPK activation. PLoS ONE, 9(5), 2014, e97781.
    • (2014) PLoS ONE , vol.9 , Issue.5 , pp. e97781
    • Sui, X.1
  • 4
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • [4] Jemal, A., et al. Global cancer statistics. CA Cancer J. Clin 61:2 (2011), 69–90.
    • (2011) CA Cancer J. Clin , vol.61 , Issue.2 , pp. 69-90
    • Jemal, A.1
  • 5
    • 84903450957 scopus 로고    scopus 로고
    • Role of beta1-integrin in colorectal cancer: case-control study
    • [5] Oh, B.Y., et al. Role of beta1-integrin in colorectal cancer: case-control study. Ann. Coloproctol 30:2 (2014), 61–70.
    • (2014) Ann. Coloproctol , vol.30 , Issue.2 , pp. 61-70
    • Oh, B.Y.1
  • 6
    • 84892805731 scopus 로고    scopus 로고
    • Cancer statistics, 2014
    • [6] Siegel, R., et al. Cancer statistics, 2014. CA Cancer J. Clin 64:1 (2014), 9–29.
    • (2014) CA Cancer J. Clin , vol.64 , Issue.1 , pp. 9-29
    • Siegel, R.1
  • 7
    • 84905384689 scopus 로고    scopus 로고
    • Molecular biomarkers for the detection of metastatic colorectal cancer cells
    • [7] Kamiyama, H., et al. Molecular biomarkers for the detection of metastatic colorectal cancer cells. World J. Gastroenterol 20:27 (2014), 8928–8938.
    • (2014) World J. Gastroenterol , vol.20 , Issue.27 , pp. 8928-8938
    • Kamiyama, H.1
  • 8
    • 84943421429 scopus 로고    scopus 로고
    • miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR
    • [8] Li, W., et al. miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR. Oncotarget 6:27 (2015), 24448–24462.
    • (2015) Oncotarget , vol.6 , Issue.27 , pp. 24448-24462
    • Li, W.1
  • 9
    • 84964539296 scopus 로고    scopus 로고
    • Recurrence after hepatic resection in colorectal cancer liver metastasis – review article
    • [9] Lintoiu-Ursut, B., Tulin, A., Constantinoiu, S., Recurrence after hepatic resection in colorectal cancer liver metastasis – review article. J. Med. Life 8 Spec Issue (2015), 12–14.
    • (2015) J. Med. Life , vol.8 Spec Issue , pp. 12-14
    • Lintoiu-Ursut, B.1    Tulin, A.2    Constantinoiu, S.3
  • 10
    • 84947019608 scopus 로고    scopus 로고
    • Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis
    • [10] Chen, H., et al. Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis. Surgery 158:6 (2015), 1704–1713.
    • (2015) Surgery , vol.158 , Issue.6 , pp. 1704-1713
    • Chen, H.1
  • 11
    • 84868198400 scopus 로고    scopus 로고
    • Meeting the biologic challenge of colorectal metastases
    • [11] Wanebo, H.J., et al. Meeting the biologic challenge of colorectal metastases. Clin. Exp. Metastasis 29:7 (2012), 821–839.
    • (2012) Clin. Exp. Metastasis , vol.29 , Issue.7 , pp. 821-839
    • Wanebo, H.J.1
  • 12
    • 34548619091 scopus 로고    scopus 로고
    • Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells
    • [12] Ishizu, K., et al. Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells. Biol. Pharm. Bull 30:9 (2007), 1779–1783.
    • (2007) Biol. Pharm. Bull , vol.30 , Issue.9 , pp. 1779-1783
    • Ishizu, K.1
  • 13
    • 84952638906 scopus 로고    scopus 로고
    • Studying cancer metastasis: existing models, challenges and future perspectives
    • [13] van Marion, D.M., et al. Studying cancer metastasis: existing models, challenges and future perspectives. Crit. Rev. Oncol. Hematol 97 (2016), 107–117.
    • (2016) Crit. Rev. Oncol. Hematol , vol.97 , pp. 107-117
    • van Marion, D.M.1
  • 14
    • 84875810421 scopus 로고    scopus 로고
    • Rebuilding cancer metastasis in the mouse
    • [14] Saxena, M., Christofori, G., Rebuilding cancer metastasis in the mouse. Mol Oncol 7:2 (2013), 283–296.
    • (2013) Mol Oncol , vol.7 , Issue.2 , pp. 283-296
    • Saxena, M.1    Christofori, G.2
  • 15
    • 8844225001 scopus 로고    scopus 로고
    • Validation of bioluminescence imaging of colorectal liver metastases in the mouse
    • [15] Smakman, N., et al. Validation of bioluminescence imaging of colorectal liver metastases in the mouse. J. Surg. Res 122:2 (2004), 225–230.
    • (2004) J. Surg. Res , vol.122 , Issue.2 , pp. 225-230
    • Smakman, N.1
  • 16
    • 64249106832 scopus 로고    scopus 로고
    • Mouse xenograft models vs GEM models for human cancer therapeutics
    • [16] Richmond, A., Su, Y., Mouse xenograft models vs GEM models for human cancer therapeutics. Dis. Model. Mech 1:2–3 (2008), 78–82.
    • (2008) Dis. Model. Mech , vol.1 , Issue.2-3 , pp. 78-82
    • Richmond, A.1    Su, Y.2
  • 17
    • 60449086469 scopus 로고    scopus 로고
    • Mouse models of colon cancer
    • [17] Taketo, M.M., Edelmann, W., Mouse models of colon cancer. Gastroenterology 136:3 (2009), 780–798.
    • (2009) Gastroenterology , vol.136 , Issue.3 , pp. 780-798
    • Taketo, M.M.1    Edelmann, W.2
  • 18
    • 84906319291 scopus 로고    scopus 로고
    • Comparison of colorectal cancer in differentially established liver metastasis models
    • [18] Lee, W.Y., et al. Comparison of colorectal cancer in differentially established liver metastasis models. Anticancer Res 34:7 (2014), 3321–3328.
    • (2014) Anticancer Res , vol.34 , Issue.7 , pp. 3321-3328
    • Lee, W.Y.1
  • 19
    • 19944424487 scopus 로고    scopus 로고
    • Mouse models of colorectal cancer and liver metastases
    • [19] Heijstek, M.W., Kranenburg, O., Borel Rinkes, I.H., Mouse models of colorectal cancer and liver metastases. Dig. Surg 22:1–2 (2005), 16–25.
    • (2005) Dig. Surg , vol.22 , Issue.1-2 , pp. 16-25
    • Heijstek, M.W.1    Kranenburg, O.2    Borel Rinkes, I.H.3
  • 20
    • 0035545961 scopus 로고    scopus 로고
    • Building ‘validated’ mouse models of human cancer
    • [20] Hann, B., Balmain, A., Building ‘validated’ mouse models of human cancer. Curr. Opin. Cell Biol 13:6 (2001), 778–784.
    • (2001) Curr. Opin. Cell Biol , vol.13 , Issue.6 , pp. 778-784
    • Hann, B.1    Balmain, A.2
  • 21
    • 0032410369 scopus 로고    scopus 로고
    • Why transgenic and knockout animal models should be used (for drug efficacy studies in cancer)
    • [21] Rosenberg, M.P., Bortner, D., Why transgenic and knockout animal models should be used (for drug efficacy studies in cancer). Cancer Metastasis Rev 17:3 (1998), 295–299.
    • (1998) Cancer Metastasis Rev , vol.17 , Issue.3 , pp. 295-299
    • Rosenberg, M.P.1    Bortner, D.2
  • 22
    • 84943374778 scopus 로고    scopus 로고
    • Mouse models of liver cancer: progress and recommendations
    • [22] He, L., et al. Mouse models of liver cancer: progress and recommendations. Oncotarget 6:27 (2015), 23306–23322.
    • (2015) Oncotarget , vol.6 , Issue.27 , pp. 23306-23322
    • He, L.1
  • 23
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • [23] Frese, K.K., Tuveson, D.A., Maximizing mouse cancer models. Nat. Rev. Cancer 7:9 (2007), 645–658.
    • (2007) Nat. Rev. Cancer , vol.7 , Issue.9 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 24
    • 13644266446 scopus 로고    scopus 로고
    • New approaches for modelling cancer mechanisms in the mouse
    • [24] Maddison, K., Clarke, A.R., New approaches for modelling cancer mechanisms in the mouse. J. Pathol 205:2 (2005), 181–193.
    • (2005) J. Pathol , vol.205 , Issue.2 , pp. 181-193
    • Maddison, K.1    Clarke, A.R.2
  • 25
    • 84908058440 scopus 로고    scopus 로고
    • Animal models and therapeutic molecular targets of cancer: utility and limitations
    • [25] Cekanova, M., Rathore, K., Animal models and therapeutic molecular targets of cancer: utility and limitations. Drug Des. Devel. Ther 8 (2014), 1911–1921.
    • (2014) Drug Des. Devel. Ther , vol.8 , pp. 1911-1921
    • Cekanova, M.1    Rathore, K.2
  • 26
    • 34347254640 scopus 로고    scopus 로고
    • Establishment of human tumor xenografts in immunodeficient mice
    • [26] Morton, C.L., Houghton, P.J., Establishment of human tumor xenografts in immunodeficient mice. Nat. Protoc 2:2 (2007), 247–250.
    • (2007) Nat. Protoc , vol.2 , Issue.2 , pp. 247-250
    • Morton, C.L.1    Houghton, P.J.2
  • 27
    • 16244367163 scopus 로고    scopus 로고
    • Modeling metastasis in vivo
    • [27] Khanna, C., Hunter, K., Modeling metastasis in vivo. Carcinogenesis 26:3 (2005), 513–523.
    • (2005) Carcinogenesis , vol.26 , Issue.3 , pp. 513-523
    • Khanna, C.1    Hunter, K.2
  • 28
    • 79251468712 scopus 로고    scopus 로고
    • Mouse models of advanced spontaneous metastasis for experimental therapeutics
    • [28] Francia, G., et al. Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nat. Rev. Cancer 11:2 (2011), 135–141.
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.2 , pp. 135-141
    • Francia, G.1
  • 29
    • 33846938312 scopus 로고    scopus 로고
    • Mouse models of breast cancer metastasis
    • [29] Fantozzi, A., Christofori, G., Mouse models of breast cancer metastasis. Breast Cancer Res, 8(4), 2006, 212.
    • (2006) Breast Cancer Res , vol.8 , Issue.4 , pp. 212
    • Fantozzi, A.1    Christofori, G.2
  • 30
    • 34547700608 scopus 로고    scopus 로고
    • Modeling metastatic breast cancer in mice
    • [30] Jonkers, J., Derksen, P.W., Modeling metastatic breast cancer in mice. J. Mammary Gland Biol. Neoplasia 12:2–3 (2007), 191–203.
    • (2007) J. Mammary Gland Biol. Neoplasia , vol.12 , Issue.2-3 , pp. 191-203
    • Jonkers, J.1    Derksen, P.W.2
  • 31
    • 23044472971 scopus 로고    scopus 로고
    • CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation
    • [31] Cabioglu, N., et al. CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation. Cancer Res 65:15 (2005), 6493–6497.
    • (2005) Cancer Res , vol.65 , Issue.15 , pp. 6493-6497
    • Cabioglu, N.1
  • 32
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • [32] Orimo, A., et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121:3 (2005), 335–348.
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1
  • 33
    • 84937418727 scopus 로고    scopus 로고
    • Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients
    • [33] Oh, B.Y., et al. Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients. Oncotarget 6:18 (2015), 16059–16068.
    • (2015) Oncotarget , vol.6 , Issue.18 , pp. 16059-16068
    • Oh, B.Y.1
  • 34
    • 2942574538 scopus 로고    scopus 로고
    • Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
    • [34] Flatmark, K., et al. Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur. J. Cancer 40:10 (2004), 1593–1598.
    • (2004) Eur. J. Cancer , vol.40 , Issue.10 , pp. 1593-1598
    • Flatmark, K.1
  • 35
    • 0034890518 scopus 로고    scopus 로고
    • Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors
    • [35] Guilbaud, N., et al. Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors. Clin. Cancer Res 7:8 (2001), 2573–2580.
    • (2001) Clin. Cancer Res , vol.7 , Issue.8 , pp. 2573-2580
    • Guilbaud, N.1
  • 36
    • 84953896833 scopus 로고    scopus 로고
    • Fluorescent-antibody targeting of insulin-like growth factor-1 receptor visualizes metastatic human colon cancer in orthotopic mouse models
    • [36] Park, J.Y., et al. Fluorescent-antibody targeting of insulin-like growth factor-1 receptor visualizes metastatic human colon cancer in orthotopic mouse models. PLoS ONE, 11(1), 2016, e0146504.
    • (2016) PLoS ONE , vol.11 , Issue.1 , pp. e0146504
    • Park, J.Y.1
  • 37
    • 85007213935 scopus 로고    scopus 로고
    • PDLIM1 stabilizes the E-cadherin/beta-catenin complex to prevent epithelial-mesenchymal transition and metastatic potential of colorectal cancer cells
    • [37] Chen, H.N., et al. PDLIM1 stabilizes the E-cadherin/beta-catenin complex to prevent epithelial-mesenchymal transition and metastatic potential of colorectal cancer cells. Cancer Res, 2015.
    • (2015) Cancer Res
    • Chen, H.N.1
  • 38
    • 0026489581 scopus 로고
    • Extensive liver metastasis from human colon cancer in nude and SCID mice after orthotopic onplantation of histologically-intact human colon carcinoma tissue
    • [38] Fu, X., et al. Extensive liver metastasis from human colon cancer in nude and SCID mice after orthotopic onplantation of histologically-intact human colon carcinoma tissue. Anticancer Res 12:5 (1992), 1395–1397.
    • (1992) Anticancer Res , vol.12 , Issue.5 , pp. 1395-1397
    • Fu, X.1
  • 39
    • 0029800343 scopus 로고    scopus 로고
    • Efficiency of orthotopic xenograft models for human colon cancers
    • [39] Pocard, M., et al. Efficiency of orthotopic xenograft models for human colon cancers. In Vivo 10:5 (1996), 463–469.
    • (1996) In Vivo , vol.10 , Issue.5 , pp. 463-469
    • Pocard, M.1
  • 40
    • 0028087881 scopus 로고
    • Metastatic models of human cancer xenografted in the nude mouse: the importance of orthotopic transplantation
    • [40] Kubota, T., Metastatic models of human cancer xenografted in the nude mouse: the importance of orthotopic transplantation. J. Cell. Biochem 56:1 (1994), 4–8.
    • (1994) J. Cell. Biochem , vol.56 , Issue.1 , pp. 4-8
    • Kubota, T.1
  • 41
    • 1942454409 scopus 로고    scopus 로고
    • Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages
    • [41] Bibby, M.C., Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages. Eur. J. Cancer 40:6 (2004), 852–857.
    • (2004) Eur. J. Cancer , vol.40 , Issue.6 , pp. 852-857
    • Bibby, M.C.1
  • 42
    • 0035057571 scopus 로고    scopus 로고
    • An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential
    • [42] Khanna, C., et al. An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential. Clin. Exp. Metastasis 18:3 (2000), 261–271.
    • (2000) Clin. Exp. Metastasis , vol.18 , Issue.3 , pp. 261-271
    • Khanna, C.1
  • 43
    • 33747494909 scopus 로고    scopus 로고
    • Mouse models in oncogenesis and cancer therapy
    • [43] Cespedes, M.V., et al. Mouse models in oncogenesis and cancer therapy. Clin. Transl. Oncol 8:5 (2006), 318–329.
    • (2006) Clin. Transl. Oncol , vol.8 , Issue.5 , pp. 318-329
    • Cespedes, M.V.1
  • 44
    • 0034056099 scopus 로고    scopus 로고
    • A nude mouse model of massive liver and lymph node metastasis of human colon cancer
    • [44] Rashidi, B., et al. A nude mouse model of massive liver and lymph node metastasis of human colon cancer. Anticancer Res 20:2A (2000), 715–722.
    • (2000) Anticancer Res , vol.20 , Issue.2A , pp. 715-722
    • Rashidi, B.1
  • 45
    • 0033057945 scopus 로고    scopus 로고
    • An ultra-metastatic model of human colon cancer in nude mice
    • [45] Sun, F.X., et al. An ultra-metastatic model of human colon cancer in nude mice. Clin. Exp. Metastasis 17:1 (1999), 41–48.
    • (1999) Clin. Exp. Metastasis , vol.17 , Issue.1 , pp. 41-48
    • Sun, F.X.1
  • 46
    • 33645744835 scopus 로고    scopus 로고
    • Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy
    • [46] Munoz, R., et al. Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy. Cancer Res 66:7 (2006), 3386–3391.
    • (2006) Cancer Res , vol.66 , Issue.7 , pp. 3386-3391
    • Munoz, R.1
  • 47
    • 49649109964 scopus 로고    scopus 로고
    • Development of a preclinical model of spontaneous human melanoma central nervous system metastasis
    • [47] Cruz-Munoz, W., et al. Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res 68:12 (2008), 4500–4505.
    • (2008) Cancer Res , vol.68 , Issue.12 , pp. 4500-4505
    • Cruz-Munoz, W.1
  • 48
    • 55749115253 scopus 로고    scopus 로고
    • Long-term progression and therapeutic response of visceral metastatic disease non-invasively monitored in mouse urine using beta-human choriogonadotropin secreting tumor cell lines
    • [48] Francia, G., et al. Long-term progression and therapeutic response of visceral metastatic disease non-invasively monitored in mouse urine using beta-human choriogonadotropin secreting tumor cell lines. Mol. Cancer Ther 7:10 (2008), 3452–3459.
    • (2008) Mol. Cancer Ther , vol.7 , Issue.10 , pp. 3452-3459
    • Francia, G.1
  • 49
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture
    • [49] Fidler, I.J., Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res 50:19 (1990), 6130–6138.
    • (1990) Cancer Res , vol.50 , Issue.19 , pp. 6130-6138
    • Fidler, I.J.1
  • 50
    • 0034998571 scopus 로고    scopus 로고
    • Critical steps in hematogenous metastasis: an overview
    • vii
    • [50] Chambers, A.F., et al. Critical steps in hematogenous metastasis: an overview. Surg. Oncol. Clin. N. Am 10:2 (2001), 243–255 vii.
    • (2001) Surg. Oncol. Clin. N. Am , vol.10 , Issue.2 , pp. 243-255
    • Chambers, A.F.1
  • 51
    • 70449732774 scopus 로고    scopus 로고
    • Analysis of cancer stem cell metastasis in xenograft animal models
    • [51] Kang, Y., Analysis of cancer stem cell metastasis in xenograft animal models. Methods Mol. Biol 568 (2009), 7–19.
    • (2009) Methods Mol. Biol , vol.568 , pp. 7-19
    • Kang, Y.1
  • 52
    • 84900559787 scopus 로고    scopus 로고
    • Colorectal cancer patient-derived xenografted tumors maintain characteristic features of the original tumors
    • [52] Cho, Y.B., et al. Colorectal cancer patient-derived xenografted tumors maintain characteristic features of the original tumors. J. Surg. Res 187:2 (2014), 502–509.
    • (2014) J. Surg. Res , vol.187 , Issue.2 , pp. 502-509
    • Cho, Y.B.1
  • 53
    • 34447123764 scopus 로고    scopus 로고
    • A new model of patient tumor-derived breast cancer xenografts for preclinical assays
    • [53] Marangoni, E., et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin. Cancer Res 13:13 (2007), 3989–3998.
    • (2007) Clin. Cancer Res , vol.13 , Issue.13 , pp. 3989-3998
    • Marangoni, E.1
  • 54
    • 78751471036 scopus 로고    scopus 로고
    • The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer
    • [54] John, T., et al. The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer. Clin. Cancer Res 17:1 (2011), 134–141.
    • (2011) Clin. Cancer Res , vol.17 , Issue.1 , pp. 134-141
    • John, T.1
  • 55
    • 84890751776 scopus 로고    scopus 로고
    • A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells
    • [55] Puig, I., et al. A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells. Clin. Cancer Res 19:24 (2013), 6787–6801.
    • (2013) Clin. Cancer Res , vol.19 , Issue.24 , pp. 6787-6801
    • Puig, I.1
  • 56
    • 84928655460 scopus 로고    scopus 로고
    • Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern
    • [56] Hiroshima, Y., et al. Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern. PLoS ONE, 10(2), 2015, e0117417.
    • (2015) PLoS ONE , vol.10 , Issue.2 , pp. e0117417
    • Hiroshima, Y.1
  • 57
    • 0034042625 scopus 로고    scopus 로고
    • An orthotopic mouse model of remetastasis of human colon cancer liver metastasis
    • [57] Rashidi, B., et al. An orthotopic mouse model of remetastasis of human colon cancer liver metastasis. Clin. Cancer Res 6:6 (2000), 2556–2561.
    • (2000) Clin. Cancer Res , vol.6 , Issue.6 , pp. 2556-2561
    • Rashidi, B.1
  • 58
    • 0023917842 scopus 로고
    • In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice
    • [58] Morikawa, K., et al. In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res 48:7 (1988), 1943–1948.
    • (1988) Cancer Res , vol.48 , Issue.7 , pp. 1943-1948
    • Morikawa, K.1
  • 59
    • 84866923492 scopus 로고    scopus 로고
    • Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer
    • [59] Julien, S., et al. Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer. Clin. Cancer Res 18:19 (2012), 5314–5328.
    • (2012) Clin. Cancer Res , vol.18 , Issue.19 , pp. 5314-5328
    • Julien, S.1
  • 60
    • 84883477300 scopus 로고    scopus 로고
    • Patient-derived tumor xenografts: transforming clinical samples into mouse models
    • [60] Siolas, D., Hannon, G.J., Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer Res 73:17 (2013), 5315–5319.
    • (2013) Cancer Res , vol.73 , Issue.17 , pp. 5315-5319
    • Siolas, D.1    Hannon, G.J.2
  • 61
    • 77953238558 scopus 로고    scopus 로고
    • Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
    • [61] Carretero, J., et al. Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. Cancer Cell 17:6 (2010), 547–559.
    • (2010) Cancer Cell , vol.17 , Issue.6 , pp. 547-559
    • Carretero, J.1
  • 62
    • 84878976471 scopus 로고    scopus 로고
    • Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation
    • [62] Martin, E.S., et al. Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. Clin. Cancer Res 19:11 (2013), 2929–2940.
    • (2013) Clin. Cancer Res , vol.19 , Issue.11 , pp. 2929-2940
    • Martin, E.S.1
  • 63
    • 0037169361 scopus 로고    scopus 로고
    • Cancer modeling in the modern era: progress and challenges
    • [63] Van Dyke, T., Jacks, T., Cancer modeling in the modern era: progress and challenges. Cell 108:2 (2002), 135–144.
    • (2002) Cell , vol.108 , Issue.2 , pp. 135-144
    • Van Dyke, T.1    Jacks, T.2
  • 64
    • 76549117990 scopus 로고    scopus 로고
    • Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment
    • [64] Hung, K.E., et al. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc. Natl. Acad. Sci. U.S.A. 107:4 (2010), 1565–1570.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , Issue.4 , pp. 1565-1570
    • Hung, K.E.1
  • 65
    • 82455208939 scopus 로고    scopus 로고
    • Genetically modified mouse models of cancer invasion and metastasis
    • [65] Rampetsreiter, P., Casanova, E., Eferl, R., Genetically modified mouse models of cancer invasion and metastasis. Drug Discov. Today Dis. Model 8:2–3 (2011), 67–74.
    • (2011) Drug Discov. Today Dis. Model , vol.8 , Issue.2-3 , pp. 67-74
    • Rampetsreiter, P.1    Casanova, E.2    Eferl, R.3
  • 66
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: molecular basis of colorectal cancer
    • [66] Markowitz, S.D., Bertagnolli, M.M., Molecular origins of cancer: molecular basis of colorectal cancer. N. Engl. J. Med 361:25 (2009), 2449–2460.
    • (2009) N. Engl. J. Med , vol.361 , Issue.25 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 67
    • 0036549015 scopus 로고    scopus 로고
    • Conditional mouse models of sporadic cancer
    • [67] Jonkers, J., Berns, A., Conditional mouse models of sporadic cancer. Nat. Rev. Cancer 2:4 (2002), 251–265.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.4 , pp. 251-265
    • Jonkers, J.1    Berns, A.2
  • 68
    • 84655164923 scopus 로고    scopus 로고
    • Experimental mouse tumour models: what can be learnt about human cancer immunology?
    • [68] Dranoff, G., Experimental mouse tumour models: what can be learnt about human cancer immunology?. Nat. Rev. Immunol 12:1 (2012), 61–66.
    • (2012) Nat. Rev. Immunol , vol.12 , Issue.1 , pp. 61-66
    • Dranoff, G.1
  • 69
    • 77955274583 scopus 로고    scopus 로고
    • The challenge of selecting the ‘right’ in vivo oncology pharmacology model
    • [69] Firestone, B., The challenge of selecting the ‘right’ in vivo oncology pharmacology model. Curr. Opin. Pharmacol 10:4 (2010), 391–396.
    • (2010) Curr. Opin. Pharmacol , vol.10 , Issue.4 , pp. 391-396
    • Firestone, B.1
  • 70
    • 34247876272 scopus 로고    scopus 로고
    • Murine models to evaluate novel and conventional therapeutic strategies for cancer
    • [70] Talmadge, J.E., et al. Murine models to evaluate novel and conventional therapeutic strategies for cancer. Am. J. Pathol 170:3 (2007), 793–804.
    • (2007) Am. J. Pathol , vol.170 , Issue.3 , pp. 793-804
    • Talmadge, J.E.1
  • 71
    • 0022965278 scopus 로고
    • Germ-line transformation of mice
    • [71] Palmiter, R.D., Brinster, R.L., Germ-line transformation of mice. Annu. Rev. Genet 20 (1986), 465–499.
    • (1986) Annu. Rev. Genet , vol.20 , pp. 465-499
    • Palmiter, R.D.1    Brinster, R.L.2
  • 72
    • 0035829651 scopus 로고    scopus 로고
    • Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice
    • [72] Brodie, S.G., et al. Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. Oncogene 20:51 (2001), 7514–7523.
    • (2001) Oncogene , vol.20 , Issue.51 , pp. 7514-7523
    • Brodie, S.G.1
  • 73
    • 0034234268 scopus 로고    scopus 로고
    • High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten ± mice
    • [73] Stambolic, V., et al. High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten ± mice. Cancer Res 60:13 (2000), 3605–3611.
    • (2000) Cancer Res , vol.60 , Issue.13 , pp. 3605-3611
    • Stambolic, V.1
  • 74
    • 0036902458 scopus 로고    scopus 로고
    • Enhanced antitumour efficacy by combining conventional chemotherapy with angiostatin or endostatin in a liver metastasis model
    • [74] te Velde, E.A., et al. Enhanced antitumour efficacy by combining conventional chemotherapy with angiostatin or endostatin in a liver metastasis model. Br. J. Surg 89:10 (2002), 1302–1309.
    • (2002) Br. J. Surg , vol.89 , Issue.10 , pp. 1302-1309
    • te Velde, E.A.1
  • 75
    • 0034928196 scopus 로고    scopus 로고
    • Rapid stereology based quantitative immunohistochemistry of dendritic cells in lymph nodes: a methodological study
    • [75] van Hensbergen, Y., et al. Rapid stereology based quantitative immunohistochemistry of dendritic cells in lymph nodes: a methodological study. Anal. Cell. Pathol 22:3 (2001), 143–149.
    • (2001) Anal. Cell. Pathol , vol.22 , Issue.3 , pp. 143-149
    • van Hensbergen, Y.1
  • 76
    • 0035060345 scopus 로고    scopus 로고
    • Unraveling human cancer in the mouse: recent refinements to modeling and analysis
    • [76] Resor, L., Bowen, T.J., Wynshaw-Boris, A., Unraveling human cancer in the mouse: recent refinements to modeling and analysis. Hum. Mol. Genet 10:7 (2001), 669–675.
    • (2001) Hum. Mol. Genet , vol.10 , Issue.7 , pp. 669-675
    • Resor, L.1    Bowen, T.J.2    Wynshaw-Boris, A.3
  • 77
    • 0037418009 scopus 로고    scopus 로고
    • Quantitative imaging of the T cell antitumor response by positron-emission tomography
    • [77] Dubey, P., et al. Quantitative imaging of the T cell antitumor response by positron-emission tomography. Proc. Natl. Acad. Sci. U.S.A. 100:3 (2003), 1232–1237.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.3 , pp. 1232-1237
    • Dubey, P.1
  • 78
    • 0036840676 scopus 로고    scopus 로고
    • Small animal imaging. Current technology and perspectives for oncological imaging
    • [78] Lewis, J.S., et al. Small animal imaging. Current technology and perspectives for oncological imaging. Eur. J. Cancer 38:16 (2002), 2173–2188.
    • (2002) Eur. J. Cancer , vol.38 , Issue.16 , pp. 2173-2188
    • Lewis, J.S.1
  • 79
    • 0036359767 scopus 로고    scopus 로고
    • Scaling down imaging: molecular mapping of cancer in mice
    • [79] Weissleder, R., Scaling down imaging: molecular mapping of cancer in mice. Nat. Rev. Cancer 2:1 (2002), 11–18.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.1 , pp. 11-18
    • Weissleder, R.1
  • 80
    • 0036290399 scopus 로고    scopus 로고
    • The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model
    • [80] Nyati, M.K., et al. The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther 9:13 (2002), 844–849.
    • (2002) Gene Ther , vol.9 , Issue.13 , pp. 844-849
    • Nyati, M.K.1
  • 81
    • 0031005838 scopus 로고    scopus 로고
    • Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression
    • [81] Chishima, T., et al. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. Cancer Res 57:10 (1997), 2042–2047.
    • (1997) Cancer Res , vol.57 , Issue.10 , pp. 2042-2047
    • Chishima, T.1
  • 82
    • 0032409738 scopus 로고    scopus 로고
    • Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis
    • [82] Hoffman, R.M., Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis. Cancer Metastasis Rev 17:3 (1998), 271–277.
    • (1998) Cancer Metastasis Rev , vol.17 , Issue.3 , pp. 271-277
    • Hoffman, R.M.1
  • 83
    • 12944327946 scopus 로고    scopus 로고
    • Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases
    • [83] Yang, M., et al. Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc. Natl. Acad. Sci. U.S.A. 97:3 (2000), 1206–1211.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , Issue.3 , pp. 1206-1211
    • Yang, M.1
  • 84
    • 84908190503 scopus 로고    scopus 로고
    • CRISPR-mediated direct mutation of cancer genes in the mouse liver
    • [84] Xue, W., et al. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature 514:7522 (2014), 380–384.
    • (2014) Nature , vol.514 , Issue.7522 , pp. 380-384
    • Xue, W.1
  • 85
    • 84933277263 scopus 로고    scopus 로고
    • Applications of the CRISPR-Cas9 system in cancer biology
    • [85] Sanchez-Rivera, F.J., Jacks, T., Applications of the CRISPR-Cas9 system in cancer biology. Nat. Rev. Cancer 15:7 (2015), 387–395.
    • (2015) Nat. Rev. Cancer , vol.15 , Issue.7 , pp. 387-395
    • Sanchez-Rivera, F.J.1    Jacks, T.2
  • 86
    • 84939252101 scopus 로고    scopus 로고
    • Precision cancer mouse models through genome editing with CRISPR-Cas9
    • [86] Mou, H., et al. Precision cancer mouse models through genome editing with CRISPR-Cas9. Genome Med, 7(1), 2015, 53.
    • (2015) Genome Med , vol.7 , Issue.1 , pp. 53
    • Mou, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.