PGC-1α overexpression via local transfection attenuates mitophagy pathway in muscle disuse atrophy

Free Radical Biology and Medicine

Volumn 93, Issue , 2016, Pages 32-40

  Kang, Chounghun ^a   Ji, Li Li ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Apoptosis; Immobilization; Mitochondria; Mitophagy; Muscle; Muscle disuse a trophy; Oxidative stress; PGC 1 overexpression

Indexed keywords

ANTIOXIDANT; BECLIN 1; CASPASE 3; MICROTUBULE ASSOCIATED PROTEIN 1A; MICROTUBULE ASSOCIATED PROTEIN 5; MITOCHONDRIAL DNA; MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1; OXIDOREDUCTASE; PARKIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BNIP3; PTEN INDUCED PUTATIVE KINASE 1; TRANSCRIPTION FACTOR FOXO; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; PPARGC1A PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HINDLIMB MUSCLE; IMMOBILIZATION; IN VIVO GENE TRANSFER; METABOLIC RATIO; MITOCHONDRIAL BIOGENESIS; MITOPHAGY; MOUSE; MUSCLE ATROPHY; MUSCLE DISUSE ATROPHY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; REMOBILIZATION; TIBIALIS ANTERIOR MUSCLE; UBIQUITINATION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; MUSCLE DISEASE; OXIDATION REDUCTION REACTION; PATHOLOGY; SKELETAL MUSCLE;

ANIMALS; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUSCLE, SKELETAL; MUSCULAR DISEASES; MUSCULAR DISORDERS, ATROPHIC; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; REACTIVE OXYGEN SPECIES; TRANSFECTION;

EID: 84957871047     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.12.032     Document Type: Article

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