PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

Journal of Physiology

Volumn 592, Issue 20, 2014, Pages 4575-4589

  Cannavino, Jessica ^a   Brocca, Lorenza ^a   Sandri, Marco ^a,b   Bottinelli, Roberto ^a,c   Pellegrino, Maria Antonietta ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^c IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ATROGIN 1; BECLIN 1; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; MUSCLE RING FINGER 1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P62; TRANSCRIPTION FACTOR NRF2; TROLOX C; 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID; ANTIOXIDANT; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; CHROMAN DERIVATIVE; DNM1L PROTEIN, MOUSE; DYNAMIN; FBXO32 PROTEIN, RAT; MUSCLE PROTEIN; NFE2L2 PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; SOD1 PROTEIN, MOUSE; SOD1 PROTEIN, RAT; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR; TRIM63 PROTEIN, MOUSE; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG MECHANISM; HINDLIMB; MALE; METABOLIC STRESS; MOUSE; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SOLEUS MUSCLE; UBIQUITINATION; UPREGULATION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; IMMOBILIZATION; METABOLISM; MUSCLE MITOCHONDRION; MUSCULAR ATROPHY; PHYSIOLOGY; SKELETAL MUSCLE CELL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; CATALASE; CHROMANS; DYNAMINS; HINDLIMB SUSPENSION; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, MUSCLE; MUSCLE FIBERS, SKELETAL; MUSCLE PROTEINS; MUSCULAR ATROPHY; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; RNA, MESSENGER; SKP CULLIN F-BOX PROTEIN LIGASES; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE-1; TRANSCRIPTION FACTORS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 84911906873     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.275545     Document Type: Article

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