Effect of food restriction on life span and immune functions in long-lived Fischer-344 x Brown Norway F1 rats

Journal of Clinical Immunology

Volumn 17, Issue 1, 1997, Pages 85-95

  Fernandes, G ^a,b,c   Venkatraman, J T ^c   Turturro, A ^d   Attwood, V G ^d   Hart, R W ^d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

aging; cytokines; food restriction; immune functions; lymphocyte subsets

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CONCANAVALIN A; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; PHYTOHEMAGGLUTININ; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; FEMALE; FLOW CYTOMETRY; LIFESPAN; LYMPHOCYTE TRANSFORMATION; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN CELL; T LYMPHOCYTE SUBPOPULATION;

AGING; ANIMALS; ANTIGENS; CROSSES, GENETIC; CYTOKINES; FEMALE; FOOD DEPRIVATION; IMMUNE SYSTEM; LONGEVITY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MITOGENS; RATS; RATS, INBRED BN; RATS, INBRED F344; RECEPTORS, INTERLEUKIN-2; SURVIVAL ANALYSIS;

EID: 0031057542     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1027344730553     Document Type: Article

References (57)

1. Weindruch R, Walford R: In The Retardation of Aging and Disease by Dietary Restriction. Springfield, IL, Charles C Thomas, 1988
2. Masoro EJ: Retardation of the aging processes by food restriction: A search for mechanisms. ISI Atlas Sci Biochem 329-332, 1988
3. Yu BP, Masoro EJ, McMahan CA: Nutritional influences on aging of Fischer-344 rats: I. Physical, metabolic, and longevity characteristics. J Gerontol 40:657-670, 1985
4. Good RA, Gajjar AJ: Diet, immunity, and longevity. In ML Hutchinson, HN Munro (eds). New York, Academic Press, 1986, pp 235-249
5. Fernandes G: Nutritional factors: Modulating effects on immune function and aging. Pharmacol Rev 36:123S-129S, 1984
6. Harrison DE, Archer JR, Astle CM: Effects of food restriction on aging: Separation of food intake and adiposity. Proc Natl Acad Sci USA 81:1835-1838, 1984
7. Makinodan T, Chang MP, Norman DC, Li SC: Vulnerability of T cell lineage to aging. In Aging and Immune Response - Cellular and Humoral Aspects, E Goidl (ed). New York, Marcel Dekker, 1987, pp 27-44
8. Thoman ML, Weigle WO: The cellular and sub-cellular bases of immunosenscene. Adv Immunol 46:221-261, 1989
9. Bloom ET, Umehara H, Bleackley RC, Okumura K, Mostowski H, Babbitt JT: Age-related decrement in cytotoxic T lymphocyte (CTL) activity is associated with decreased levels of mRNA encoded by two CTL-associated serine esterase genes and the perform gene in mice. Eur J Immunol 20:2309-2316, 1990
10. Vitetta ES, Berton MT, Burger C, Kepron M, Lee WT, Yin X-M: Memory B and T cells. Annu Rev Immunol 9:193-217, 1991
11. Miller RA: Defective calcium signal generation in a T cell subset that accumulates in old mice. Ann NY Acad Sci 568:271-276, 1989
12. Weksler ME, Russo C, Siskind GW: Peripheral T cells select the B cell repertoire in old mice. Immunol Rev 110:173-185, 1989
13. Murasko DM, Weiner P, Kaye D: Decline in mitogen induced proliferation of lymphocytes with increasing age. Clin Exp Immunol 70:440-448, 1987
14. high lymphocytes accumulate with age in mice and respond poorly to concanavalin-A. Eur J Immunol 19:977-982, 1989
15. Grossmann A, Ledbetter JA, Rabinovitch PS: Aging-related deficiency in intracellular calcium response to anti-CD3 or concanavalin-A in murine T cell subsets. J Gerontol 45:B81-B86, 1990
16. Holbrook NJ, Chopra RK, McCoy MT, Nagel JE, Powers DC, Alder WH, Schneider EL: Expression of IL-2 and IL-2R in aging rats. Cell Immunol 120:1-9, 1989
17. Wu W, Pahlavani M, Cheung HT, Richardson A: The effect of aging on the expression of interleukin-2 messenger ribonucleic acid. Cell Immunol 100:224-231, 1986
18. Proust JJ, Kittur DS, Buchholz MA, Nordin AA: Restricted expression of mitogen-induced high-affinity IL-2 receptors in aging mice. J Immunol 141:4209-4216, 1988
19. Fong TC, Makinodan T: In situ hybridization analysis of the age-associated decline in IL-2 mRNA expressing murine T cells. Cell Immunol 118:199-207, 1989
20. Janeway CA Jr: Self superantigens? Cell 63:653-661, 1990
21. Callahan JE, Herman A, Kappler JW, Marrack P: Stimulation of B10.BR T cells with superantigenic staphylococcal toxins. J Immunol 144:2473-2479, 1990
22. Coffin JM: Superantigens and endogenous retroviruses: A confluence of puzzles. Science 255:411-413, 1992
23. Marrack P, Kappler J: The staphylococcal enterotoxins and their relatives. Science 248:705-711, 1990
24. Bronson RT: Rate of occurrence of lesions in 20 inbred and hybrid genotyoes of rats and mice sacrificed at six month intervals during the first year of life. In Genetic Effects on Aging II, DE Harrison (ed). Caldwell, NJ, Telford Press, 1992, pp 280-358
25. Goonewardene MI, Murasko DM: Age associated changes in mitogen induced proliferation and cytokine production by lymphocytes of the long-lived Brown Norway rat. Mech Age Dev 71:199-212, 1993
26. Duffy PH, Feuers RJ, Leaky JEA, Nakamura KD, Turturro A, Hart RW: Ettect of chronic calorie restriction on physiological variables related to energy metabolism in male Fischer-344 rat. Mech Age Dev 48:117-133, 1989
27. Iwai H, Fernandes G: Immunological functions in food-restricted rats: Enhanced expression of high-affinity IL-2 receptors on splenic T cells. Immunol Lett 23:125-132, 1989
28. Sharrow SO: Analysis of flow cytometry data. In Current Protocols in Immunology, Vol 1, JE Coligan, AM Kruisbeek, DH Margulies, EM Shevach, W Strober (eds). New York, Green, Wiley-Interscience, 1991. p 52
29. Gillis SM, Perm M, Ou W, Smith K: T cell growth factor: Parameters of production and a quantitative microassay for activity. J Immunol 120:2027-2031, 1978
30. Espevik T: A highly sensitive cell line. WEH1 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J Immunol Methods 95:99-105, 1986
31. Flescher F, Fossum D, Gray PJ, Fernandes G, Harper M, Talal N: Aspirin-like drugs prime human T cells: Modulation of intracellular calcium concentrations. J Immunol 146:2553-2559, 1991
32. + influx by food restriction in aging rats. Aging Immunol Infect Dis 2:117-125, 1990
33. Lesourd BM, Meaume S: Cell-mediated immunity changes in ageing, relative importance of subpopulation switches and of nutritional factors. Immunol Lett 40:235-242, 1994
34. Engwerda CR, Handwerger BS, Fox BS: Aged T cells are hyporesponsive to costimulation mediated by CD28. J Immunol 152:3740-3747, 1994
35. Goonewardene MI, Murasko DM: Age-associated changes in mitogen-induced lymphoproliferation and lymphokine production in the long-lived brown-Norway rat: effect of calorie restriction. Mech Age Dev 83:103-116, 1995
36. Callahan JE, Kappler JW, Marrack P: Unexpected expansion of CD8-bearing cells in old mice. J Immunol 151:6657-6669, 1993
37. De Paioli P, Battistin S, Santini GF: Age-related changes in human lymphocyte subsets: Progressive reduction of the CD4 CD45R (suppressor inducer) population. Clin Immunol 48:290-299, 1988
38. Sanders ME, Makgoba MW: Human naive and memory T cells: Reinterpretation of helper-inducer and suppressor-inducer subsets. Immunol Today 9:195-199, 1988
39. Walker C, Gauchat JF, De Week AL, Stadler BM: Analysis of leucocyte markers in elderly individuals. Aging Immunol Infect Dis 2:31-37, 1990
40. Warren RP, Yonk LJ, Burger RA, Singh VK: Age-related changes in CD45R and CDW29 helper T cells in human subjects. Aging Immunol Infect Dis 2:91-94, 1990
41. + T cell subsets defined by CD45RB: CD45RB cells have a much stronger response to recall antigens, whereas polyclonally activated cells of both subsets are equally efficient producers of IFN in the presence of exogenous IL-2. Cell Immunol 132:391-399, 1991
42. + phenotype. J Exp Med 169:653-662, 1989
43. 1 female mice. Aging Immunol Infect Dis 5:13-25, 1994
44. Zhao T, Edwards CK, Mountz JD: Prevention of age-related T cell apoptosis defect in CD2-fas-transgenic mice. J Exp Med 182:129-137, 1995
45. + T cells after antigenic stimulation. Resolution of two populations of memory T cells that both secrete IL-4. J Exp Med 169:2245-2250, 1989
46. Bottomly KA, Luqman M, Greenbaum L, Carding S, West J, Pasqualini T, Murphy DB: A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol 19:617-623, 1989
47. Weksler ME, Schwab R: The immunogenetics of immune senescence. Exp Clin Immunogenet 9:182-187, 1992
48. + T cells with changes in frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol 151:578-587, 1993
49. Kubo M, Cinader B: Polymorphism of age-related changes in interleukin production: differential changes of T helper populations, synthesizing IL-2, IL-3, and IL-4. Eur J Immunol 20:1289-1296, 1990
50. Hobbs MV, Weigle WO, Noonan DJ, Torbett BE, McEvilly RJ, Koch RJ, Cardenas GJ, Ernst DN: Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol 150:3602-3614, 1993
51. + cell subsets from young and old mice. Cell Immunol 154:264-272, 1994
52. Okamura M, Fujii Y, Takauchi Y, Inada K, Nakahara K, Matsuda H: Age-related accumulation of LFA-lhigh cells in a CD8 + CD45 RA high T cell population. Eur J Immunol 23:1057-1063, 1993
53. Xu X, Beckman I, Dimopoulos K, Ahern M, Bradley J: Agerelated changes in the expression of T cell activation antigens following phytohemagglutinin stimulation. Exp Clin Immunogenet 9:203-211, 1992
54. Beckman I, Shepherd K, Firgaire F, Ahern M: Age-related defects in CD2 receptor-induced activation in human T-cell subsets. Immunology 86:533-536, 1995
55. Venkatraman JT, Fernandes G: Modulation of age-related alter-ations in membrane composition and receptor associated immune functions by food restriction. Mech Age Dev 63:27-44, 1991
56. Goodwin JS, Ceuppens J: Regulation of immune responses by prostaglandins. J Clin Immunol 3:295-315, 1983
57. Flurkey K, Stadecker M, Miller RA: Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: A key factor in age-related immunodeficiency. Eur J Immunol 22:931-935, 1992