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Volumn 33, Issue 4, 2016, Pages 309-323

β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases

Author keywords

Breast cancer; Metastasis; Prognostic score; WNT signaling

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FRIZZLED PROTEIN; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; WNT PROTEIN; ESTROGEN RECEPTOR ALPHA; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; ROR1 PROTEIN, HUMAN; ROR2 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84957678067     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-016-9780-3     Document Type: Article
Times cited : (32)

References (61)
  • 1
    • 84891372505 scopus 로고    scopus 로고
    • Cancer survival in Europe 1999–2007 by country and age: results of EUROCARE–5-a population-based study
    • PID: 24314615
    • De Angelis R et al (2014) Cancer survival in Europe 1999–2007 by country and age: results of EUROCARE–5-a population-based study. Lancet Oncol 15(1):23–34
    • (2014) Lancet Oncol , vol.15 , Issue.1 , pp. 23-34
    • De Angelis, R.1
  • 3
    • 80053230030 scopus 로고    scopus 로고
    • The role of surgery in metastatic breast cancer
    • PID: 21944030
    • Ruiterkamp J, Ernst MF (2011) The role of surgery in metastatic breast cancer. Eur J Cancer 47(Suppl 3):S6–S22
    • (2011) Eur J Cancer , vol.47 , pp. S6-S22
    • Ruiterkamp, J.1    Ernst, M.F.2
  • 4
    • 85027920862 scopus 로고    scopus 로고
    • Liver-directed treatments for metastatic colorectal cancer
    • PID: 24952016
    • Choti MA (2014) Liver-directed treatments for metastatic colorectal cancer. Curr Treat Options Oncol 15(3):456–464
    • (2014) Curr Treat Options Oncol , vol.15 , Issue.3 , pp. 456-464
    • Choti, M.A.1
  • 5
    • 84902685833 scopus 로고    scopus 로고
    • Is there a role for surgical resections of hepatic breast cancer metastases?
    • PID: 24895817
    • Elsberger B, Roxburgh CS, Horgan PG (2014) Is there a role for surgical resections of hepatic breast cancer metastases? Hepatogastroenterology 61(129):181–186
    • (2014) Hepatogastroenterology , vol.61 , Issue.129 , pp. 181-186
    • Elsberger, B.1    Roxburgh, C.S.2    Horgan, P.G.3
  • 6
    • 84921382177 scopus 로고    scopus 로고
    • Advances in understanding of colorectal liver metastasis and implications for the clinic
    • PID: 25033964
    • Page AJ et al (2014) Advances in understanding of colorectal liver metastasis and implications for the clinic. Expert Rev Gastroenterol Hepatol 9(2):245–259
    • (2014) Expert Rev Gastroenterol Hepatol , vol.9 , Issue.2 , pp. 245-259
    • Page, A.J.1
  • 7
    • 84863688392 scopus 로고    scopus 로고
    • A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine
    • COI: 1:CAS:528:DC%2BC38XhsVKrsL%2FJ, PID: 22649126
    • Krop IE et al (2012) A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine. J Clin Oncol 30(26):3234–3241
    • (2012) J Clin Oncol , vol.30 , Issue.26 , pp. 3234-3241
    • Krop, I.E.1
  • 8
    • 84880943846 scopus 로고    scopus 로고
    • General principles of tumour biology in visceral surgery
    • COI: 1:STN:280:DC%2BC3sfmvFKrsA%3D%3D, PID: 23918723
    • Emons G, Ghadimi M, Grade M (2015) General principles of tumour biology in visceral surgery. Zentralbl Chir 140(1):74–82
    • (2015) Zentralbl Chir , vol.140 , Issue.1 , pp. 74-82
    • Emons, G.1    Ghadimi, M.2    Grade, M.3
  • 9
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: from dissemination to organ-specific colonization
    • COI: 1:CAS:528:DC%2BD1MXjsFSrsr4%3D, PID: 19308067
    • Nguyen DX, Bos PD, Massague J (2009) Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9(4):274–284
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 10
    • 84885352426 scopus 로고    scopus 로고
    • Origins of metastatic traits
    • COI: 1:CAS:528:DC%2BC3sXhs1Wks7rP, PID: 24135279
    • Vanharanta S, Massague J (2013) Origins of metastatic traits. Cancer Cell 24(4):410–421
    • (2013) Cancer Cell , vol.24 , Issue.4 , pp. 410-421
    • Vanharanta, S.1    Massague, J.2
  • 11
    • 34247269026 scopus 로고    scopus 로고
    • Genetic determinants of cancer metastasis
    • COI: 1:CAS:528:DC%2BD2sXktlSltLc%3D, PID: 17440531
    • Nguyen DX, Massague J (2007) Genetic determinants of cancer metastasis. Nat Rev Genet 8(5):341–352
    • (2007) Nat Rev Genet , vol.8 , Issue.5 , pp. 341-352
    • Nguyen, D.X.1    Massague, J.2
  • 12
    • 79953300698 scopus 로고    scopus 로고
    • The seed and soil hypothesis revisited—the role of tumor-stroma interactions in metastasis to different organs
    • Langley RR, Fidler IJ (2011) The seed and soil hypothesis revisited—the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer (J Int Cancer), vol 128(11), pp 2527–2535
    • (2011) Int J Cancer (J Int Cancer) , vol.128 , Issue.11 , pp. 2527-2535
    • Langley, R.R.1    Fidler, I.J.2
  • 13
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • COI: 1:CAS:528:DC%2BC38XktFOgtbw%3D, PID: 22397650
    • Gerlinger M et al (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 366(10):883–892
    • (2012) N Engl J Med , vol.366 , Issue.10 , pp. 883-892
    • Gerlinger, M.1
  • 14
    • 84899428170 scopus 로고    scopus 로고
    • Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinoma
    • Huang Y et al (2014) Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinoma. Int J Cancer (J Int Cancer), vol 135(1), pp 78–87
    • (2014) Int J Cancer (J Int Cancer) , vol.135 , Issue.1 , pp. 78-87
    • Huang, Y.1
  • 15
    • 63049102497 scopus 로고    scopus 로고
    • Parallel progression of primary tumours and metastases
    • COI: 1:CAS:528:DC%2BD1MXjsFSrsr8%3D, PID: 19308069
    • Klein CA (2009) Parallel progression of primary tumours and metastases. Nat Rev Cancer 9(4):302–312
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 302-312
    • Klein, C.A.1
  • 16
    • 73449133770 scopus 로고    scopus 로고
    • Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis
    • Stoecklein NH, Klein CA (2010) Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis. Int J Cancer (J Int Cancer), vol 126(3), pp 589–98
    • (2010) Int J Cancer (J Int Cancer) , vol.126 , Issue.3 , pp. 589-598
    • Stoecklein, N.H.1    Klein, C.A.2
  • 17
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • COI: 1:CAS:528:DC%2BD38XlslGqsLw%3D, PID: 12154349
    • Chambers AF, Groom AC, Macdonald IC (2002) Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2(8):563–572
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    Macdonald, I.C.3
  • 18
    • 84880698423 scopus 로고    scopus 로고
    • Carcinoma cells misuse the host tissue damage response to invade the brain
    • PID: 23832647
    • Chuang HN et al (2013) Carcinoma cells misuse the host tissue damage response to invade the brain. Glia 61(8):1331–1346
    • (2013) Glia , vol.61 , Issue.8 , pp. 1331-1346
    • Chuang, H.N.1
  • 19
    • 73849129203 scopus 로고    scopus 로고
    • Real-time imaging reveals the single steps of brain metastasis formation
    • PID: 20023634
    • Kienast Y et al (2009) Real-time imaging reveals the single steps of brain metastasis formation. Nat Med 16(1):116–122
    • (2009) Nat Med , vol.16 , Issue.1 , pp. 116-122
    • Kienast, Y.1
  • 20
    • 84896690172 scopus 로고    scopus 로고
    • Serpins promote cancer cell survival and vascular co-option in brain metastasis
    • COI: 1:CAS:528:DC%2BC2cXjsVWnsLs%3D, PID: 24581498
    • Valiente M et al (2014) Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell 156(5):1002–1016
    • (2014) Cell , vol.156 , Issue.5 , pp. 1002-1016
    • Valiente, M.1
  • 21
    • 77956603258 scopus 로고    scopus 로고
    • Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way
    • PID: 20549749
    • Pukrop T et al (2010) Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia 58(12):1477–1489
    • (2010) Glia , vol.58 , Issue.12 , pp. 1477-1489
    • Pukrop, T.1
  • 22
    • 84876497593 scopus 로고    scopus 로고
    • Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear beta-catenin in cerebral metastasis of lung adenocarcinomas
    • COI: 1:CAS:528:DC%2BC3sXlsFWqs7c%3D, PID: 23224985
    • Bleckmann A et al (2013) Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear beta-catenin in cerebral metastasis of lung adenocarcinomas. Clin Exp Metastasis 30(4):471–482
    • (2013) Clin Exp Metastasis , vol.30 , Issue.4 , pp. 471-482
    • Bleckmann, A.1
  • 23
    • 79952358403 scopus 로고    scopus 로고
    • beta-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
    • COI: 1:CAS:528:DC%2BC3MXivVOgtLk%3D, PID: 21173432
    • Klemm F et al (2011) beta-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis. Carcinogenesis 32(3):434–442
    • (2011) Carcinogenesis , vol.32 , Issue.3 , pp. 434-442
    • Klemm, F.1
  • 24
    • 84907487414 scopus 로고    scopus 로고
    • Stem cell signaling. An integral program for tissue renewal and regeneration: wnt signaling and stem cell control
    • PID: 25278615
    • Clevers H, Loh KM, Nusse R (2014) Stem cell signaling. An integral program for tissue renewal and regeneration: wnt signaling and stem cell control. Science 346(6205):1248012
    • (2014) Science , vol.346 , Issue.6205 , pp. 1248012
    • Clevers, H.1    Loh, K.M.2    Nusse, R.3
  • 26
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • COI: 1:CAS:528:DC%2BD2MXjtFOmsrw%3D, PID: 15829953
    • Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434(7035):843–850
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 27
    • 77955155919 scopus 로고    scopus 로고
    • The multiple phases and faces of wnt signaling during cardiac differentiation and development
    • COI: 1:CAS:528:DC%2BC3cXpt1Kqsr0%3D, PID: 20651295
    • Gessert S, Kuhl M (2010) The multiple phases and faces of wnt signaling during cardiac differentiation and development. Circ Res 107(2):186–199
    • (2010) Circ Res , vol.107 , Issue.2 , pp. 186-199
    • Gessert, S.1    Kuhl, M.2
  • 28
    • 84870816403 scopus 로고    scopus 로고
    • Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
    • COI: 1:CAS:528:DC%2BC38XhslKqtL3E, PID: 23201163
    • Ocana OH et al (2012) Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22(6):709–724
    • (2012) Cancer Cell , vol.22 , Issue.6 , pp. 709-724
    • Ocana, O.H.1
  • 29
    • 84887981252 scopus 로고    scopus 로고
    • Mechanisms governing metastatic dormancy and reactivation
    • COI: 1:CAS:528:DC%2BC3sXhslCltrfJ, PID: 24209616
    • Giancotti FG (2013) Mechanisms governing metastatic dormancy and reactivation. Cell 155(4):750–764
    • (2013) Cell , vol.155 , Issue.4 , pp. 750-764
    • Giancotti, F.G.1
  • 30
    • 79351468712 scopus 로고    scopus 로고
    • Activation of beta-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters
    • PID: 21284870
    • Li J, Zhou BP (2011) Activation of beta-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer 11:49
    • (2011) BMC Cancer , vol.11 , pp. 49
    • Li, J.1    Zhou, B.P.2
  • 31
    • 0035138178 scopus 로고    scopus 로고
    • Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling
    • PID: 11196175
    • van de Wetering M et al (2001) Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. Cancer Res 61(1):278–284
    • (2001) Cancer Res , vol.61 , Issue.1 , pp. 278-284
    • van de Wetering, M.1
  • 32
    • 0037504665 scopus 로고    scopus 로고
    • Transactivation of vimentin by beta-catenin in human breast cancer cells
    • COI: 1:CAS:528:DC%2BD3sXjsleht7c%3D, PID: 12750294
    • Gilles C et al (2003) Transactivation of vimentin by beta-catenin in human breast cancer cells. Cancer Res 63(10):2658–2664
    • (2003) Cancer Res , vol.63 , Issue.10 , pp. 2658-2664
    • Gilles, C.1
  • 33
    • 84863251015 scopus 로고    scopus 로고
    • ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth
    • COI: 1:CAS:528:DC%2BC38XjvFajtbw%3D, PID: 22403610
    • Zhang S et al (2012) ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth. PLoS ONE 7(3):e31127
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. e31127
    • Zhang, S.1
  • 34
    • 84921022827 scopus 로고    scopus 로고
    • Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both beta-catenin dependent and independent Wnt signalling
    • COI: 1:CAS:528:DC%2BC2cXhsFyisbzL, PID: 25209439
    • Henry C et al (2015) Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both beta-catenin dependent and independent Wnt signalling. J Cancer Res Clin Oncol 141(2):243–254
    • (2015) J Cancer Res Clin Oncol , vol.141 , Issue.2 , pp. 243-254
    • Henry, C.1
  • 35
    • 83155181734 scopus 로고    scopus 로고
    • Wnt5a: its signalling, functions and implication in diseases
    • COI: 1:CAS:528:DC%2BC38Xit1SlsA%3D%3D
    • Kikuchi A et al (2012) Wnt5a: its signalling, functions and implication in diseases. Acta Physiol 204(1):17–33
    • (2012) Acta Physiol , vol.204 , Issue.1 , pp. 17-33
    • Kikuchi, A.1
  • 36
    • 39749108763 scopus 로고    scopus 로고
    • The complex pathways of Wnt 5a in cancer progression
    • COI: 1:CAS:528:DC%2BD1cXitlGnur4%3D, PID: 17952396
    • Pukrop T, Binder C (2008) The complex pathways of Wnt 5a in cancer progression. J Mol Med 86(3):259–266
    • (2008) J Mol Med , vol.86 , Issue.3 , pp. 259-266
    • Pukrop, T.1    Binder, C.2
  • 37
    • 77956283416 scopus 로고    scopus 로고
    • Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region
    • COI: 1:CAS:528:DC%2BC3cXhtVCkt7%2FI, PID: 20660756
    • Witte F et al (2010) Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region. Proc Natl Acad Sci USA 107(32):14211–14216
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.32 , pp. 14211-14216
    • Witte, F.1
  • 38
    • 84923764475 scopus 로고    scopus 로고
    • Distinct functionality of dishevelled isoforms on Ca2 +/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation
    • COI: 1:CAS:528:DC%2BC2MXktF2gtLs%3D, PID: 25568338
    • Gentzel M et al (2015) Distinct functionality of dishevelled isoforms on Ca2 +/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation. Mol Biol Cell 26(5):966–977
    • (2015) Mol Biol Cell , vol.26 , Issue.5 , pp. 966-977
    • Gentzel, M.1
  • 39
    • 3342904989 scopus 로고    scopus 로고
    • Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases
    • COI: 1:CAS:528:DC%2BD2cXmtF2ntrk%3D, PID: 15044327
    • Hagemann T et al (2004) Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. Carcinogenesis 25(8):1543–1549
    • (2004) Carcinogenesis , vol.25 , Issue.8 , pp. 1543-1549
    • Hagemann, T.1
  • 40
    • 40449131620 scopus 로고    scopus 로고
    • Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study
    • PID: 17922920
    • van de Vijver M et al (2007) Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study. Breast Cancer Res 9(5):R68
    • (2007) Breast Cancer Res , vol.9 , Issue.5 , pp. R68
    • van de Vijver, M.1
  • 41
    • 33750310901 scopus 로고    scopus 로고
    • REporting recommendations for tumor MARKer prognostic studies (REMARK)
    • PID: 16932852
    • McShane LM et al (2006) REporting recommendations for tumor MARKer prognostic studies (REMARK). Breast Cancer Res Treat 100(2):229–235
    • (2006) Breast Cancer Res Treat , vol.100 , Issue.2 , pp. 229-235
    • McShane, L.M.1
  • 42
    • 77954365864 scopus 로고    scopus 로고
    • Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization
    • COI: 1:CAS:528:DC%2BC3cXpvVOqsbs%3D, PID: 20457807
    • Nishita M et al (2010) Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization. Mol Cell Biol 30(14):3610–3619
    • (2010) Mol Cell Biol , vol.30 , Issue.14 , pp. 3610-3619
    • Nishita, M.1
  • 43
    • 84908120492 scopus 로고    scopus 로고
    • Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling
    • COI: 1:CAS:528:DC%2BC2cXhslGjsr7N, PID: 25168481
    • Gao S et al (2014) Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling. Cancer Res 74(20):5866–5877
    • (2014) Cancer Res , vol.74 , Issue.20 , pp. 5866-5877
    • Gao, S.1
  • 44
    • 84868308598 scopus 로고    scopus 로고
    • Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma
    • COI: 1:CAS:528:DC%2BC38Xhslarsr7K, PID: 23022960
    • Hegazy SA et al (2013) Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma. Cell Signal 25(1):295–307
    • (2013) Cell Signal , vol.25 , Issue.1 , pp. 295-307
    • Hegazy, S.A.1
  • 45
    • 84871813739 scopus 로고    scopus 로고
    • AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/beta-catenin signaling activity
    • COI: 1:CAS:528:DC%2BC3sXptVagtA%3D%3D, PID: 23301094
    • Kwan HT et al (2013) AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/beta-catenin signaling activity. PLoS ONE 8(1):e53597
    • (2013) PLoS ONE , vol.8 , Issue.1 , pp. e53597
    • Kwan, H.T.1
  • 46
    • 77956167800 scopus 로고    scopus 로고
    • Dishevelled-1 and dishevelled-3 affect cell invasion mainly through canonical and noncanonical Wnt pathway, respectively, and associate with poor prognosis in nonsmall cell lung cancer
    • COI: 1:CAS:528:DC%2BC3cXoslegt7k%3D, PID: 20572159
    • Zhao Y et al (2010) Dishevelled-1 and dishevelled-3 affect cell invasion mainly through canonical and noncanonical Wnt pathway, respectively, and associate with poor prognosis in nonsmall cell lung cancer. Mol Carcinog 49(8):760–770
    • (2010) Mol Carcinog , vol.49 , Issue.8 , pp. 760-770
    • Zhao, Y.1
  • 47
    • 33750899497 scopus 로고    scopus 로고
    • Toothbrush-thinking seizures
    • PID: 17116043
    • Navarro V et al (2006) Toothbrush-thinking seizures. Epilepsia 47(11):1971–1973
    • (2006) Epilepsia , vol.47 , Issue.11 , pp. 1971-1973
    • Navarro, V.1
  • 48
    • 84907294407 scopus 로고    scopus 로고
    • Surgical management of breast cancer liver metastases
    • COI: 1:STN:280:DC%2BC2M7ktFGisw%3D%3D, PID: 25244979
    • Sabol M et al (2014) Surgical management of breast cancer liver metastases. Neoplasma 61(5):601–606
    • (2014) Neoplasma , vol.61 , Issue.5 , pp. 601-606
    • Sabol, M.1
  • 49
    • 84911474269 scopus 로고    scopus 로고
    • Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Van Cutsem E et al (2014) Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 25(Suppl 3):1–9
    • (2014) Ann Oncol , vol.25 , pp. 1-9
    • Van Cutsem, E.1
  • 50
    • 79957572444 scopus 로고    scopus 로고
    • Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
    • COI: 1:CAS:528:DC%2BC3MXntVait7k%3D, PID: 21637790
    • Bachmeier B et al (2011) Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells. PLoS ONE 6(5):e20550
    • (2011) PLoS ONE , vol.6 , Issue.5 , pp. e20550
    • Bachmeier, B.1
  • 51
    • 84925611946 scopus 로고    scopus 로고
    • Microenvironmental regulation of therapeutic response in cancer
    • PID: 25540894
    • Klemm F, Joyce JA (2014) Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol 25(4):198–213
    • (2014) Trends Cell Biol , vol.25 , Issue.4 , pp. 198-213
    • Klemm, F.1    Joyce, J.A.2
  • 52
    • 84891834887 scopus 로고    scopus 로고
    • Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy
    • COI: 1:CAS:528:DC%2BC3sXhs1yksbnN, PID: 24048441
    • Devaud C et al (2014) Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy. Mol Ther 22(1):18–27
    • (2014) Mol Ther , vol.22 , Issue.1 , pp. 18-27
    • Devaud, C.1
  • 53
    • 70349969478 scopus 로고    scopus 로고
    • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
    • COI: 1:CAS:528:DC%2BD1MXht1Cisb%2FM, PID: 19812674
    • Shah SP et al (2009) Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461(7265):809–813
    • (2009) Nature , vol.461 , Issue.7265 , pp. 809-813
    • Shah, S.P.1
  • 54
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • COI: 1:CAS:528:DC%2BC38XlsF2jtw%3D%3D, PID: 22237025
    • Ding L et al (2012) Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481(7382):506–510
    • (2012) Nature , vol.481 , Issue.7382 , pp. 506-510
    • Ding, L.1
  • 55
    • 84925679415 scopus 로고    scopus 로고
    • Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis
    • PID: 25730902
    • Kroigard AB et al (2015) Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis. Oncotarget 6(8):5634–5649
    • (2015) Oncotarget , vol.6 , Issue.8 , pp. 5634-5649
    • Kroigard, A.B.1
  • 56
    • 84927749951 scopus 로고    scopus 로고
    • Management of brain metastases in the era of targeted and immunomodulatory therapies
    • PID: 25952489
    • Brastianos PK, Cahill DP (2015) Management of brain metastases in the era of targeted and immunomodulatory therapies. Oncology 29(4):261–263
    • (2015) Oncology , vol.29 , Issue.4 , pp. 261-263
    • Brastianos, P.K.1    Cahill, D.P.2
  • 57
    • 84945452059 scopus 로고    scopus 로고
    • Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance
    • COI: 1:CAS:528:DC%2BC2MXhs12qurjE, PID: 26172396
    • Saunus JM et al (2015) Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance. J Pathol 237(3):363–378
    • (2015) J Pathol , vol.237 , Issue.3 , pp. 363-378
    • Saunus, J.M.1
  • 58
    • 84871563123 scopus 로고    scopus 로고
    • Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
    • COI: 1:CAS:528:DC%2BC38XhvVymu7nP, PID: 23260141
    • Luga V et al (2012) Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 151(7):1542–1556
    • (2012) Cell , vol.151 , Issue.7 , pp. 1542-1556
    • Luga, V.1
  • 59
    • 33645774667 scopus 로고    scopus 로고
    • Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
    • COI: 1:CAS:528:DC%2BD28Xjslejsr0%3D, PID: 16569699
    • Pukrop T et al (2006) Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. Proc Natl Acad Sci USA 103(14):5454–5459
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.14 , pp. 5454-5459
    • Pukrop, T.1
  • 60
    • 84946215072 scopus 로고    scopus 로고
    • Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
    • COI: 1:CAS:528:DC%2BC2MXhvVWqsr3O, PID: 26410082
    • Brastianos PK et al (2015) Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets. Cancer Discov 5(11):1164–1177
    • (2015) Cancer Discov , vol.5 , Issue.11 , pp. 1164-1177
    • Brastianos, P.K.1
  • 61
    • 84980047658 scopus 로고    scopus 로고
    • Next-generation sequencing of stage IV squamous cell lung cancers reveals an association of PI3 K aberrations and evidence of clonal heterogeneity in patients with brain metastases
    • COI: 1:CAS:528:DC%2BC2MXps1CgsLg%3D, PID: 25929848
    • Paik PK et al (2015) Next-generation sequencing of stage IV squamous cell lung cancers reveals an association of PI3 K aberrations and evidence of clonal heterogeneity in patients with brain metastases. Cancer Discov 5(6):610–621
    • (2015) Cancer Discov , vol.5 , Issue.6 , pp. 610-621
    • Paik, P.K.1


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