-
1
-
-
0027074850
-
A novel family of cell surface receptors with tyrosine kinase-like domain
-
Masiakowski P, Carroll RD, (1992) A novel family of cell surface receptors with tyrosine kinase-like domain. J Biol Chem 267: 26181-26190.
-
(1992)
J Biol Chem
, vol.267
, pp. 26181-26190
-
-
Masiakowski, P.1
Carroll, R.D.2
-
2
-
-
19644383031
-
Identification and characterization of rat Ror1 and Ror2 genes in silico
-
Katoh M, Katoh M, (2005) Identification and characterization of rat Ror1 and Ror2 genes in silico. Int J Mol Med 15: 533-538.
-
(2005)
Int J Mol Med
, vol.15
, pp. 533-538
-
-
Katoh, M.1
Katoh, M.2
-
3
-
-
0036159121
-
The Ror receptor tyrosine kinase family
-
Forrester WC, (2002) The Ror receptor tyrosine kinase family. Cell Mol Life Sci 59: 83-96.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 83-96
-
-
Forrester, W.C.1
-
4
-
-
6544275956
-
Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system
-
Oishi I, Takeuchi S, Hashimoto R, Nagabukuro A, Ueda T, et al. (1999) Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system. Genes Cells 4: 41-56.
-
(1999)
Genes Cells
, vol.4
, pp. 41-56
-
-
Oishi, I.1
Takeuchi, S.2
Hashimoto, R.3
Nagabukuro, A.4
Ueda, T.5
-
5
-
-
0027205387
-
Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases
-
Wilson C, Goberdhan DC, Steller H, (1993) Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases. Proc Natl Acad Sci U S A 90: 7109-7113.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7109-7113
-
-
Wilson, C.1
Goberdhan, D.C.2
Steller, H.3
-
6
-
-
0034051682
-
Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development
-
DeChiara TM, Kimble RB, Poueymirou WT, Rojas J, Masiakowski P, et al. (2000) Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development. Nat Genet 24: 271-274.
-
(2000)
Nat Genet
, vol.24
, pp. 271-274
-
-
DeChiara, T.M.1
Kimble, R.B.2
Poueymirou, W.T.3
Rojas, J.4
Masiakowski, P.5
-
7
-
-
6744265274
-
Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation
-
Takeuchi S, Takeda K, Oishi I, Nomi M, Ikeya M, et al. (2000) Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation. Genes Cells 5: 71-78.
-
(2000)
Genes Cells
, vol.5
, pp. 71-78
-
-
Takeuchi, S.1
Takeda, K.2
Oishi, I.3
Nomi, M.4
Ikeya, M.5
-
8
-
-
0035192873
-
Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases
-
Nomi M, Oishi I, Kani S, Suzuki H, Matsuda T, et al. (2001) Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases. Mol Cell Biol 21: 8329-8335.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8329-8335
-
-
Nomi, M.1
Oishi, I.2
Kani, S.3
Suzuki, H.4
Matsuda, T.5
-
9
-
-
0034425405
-
Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2
-
Afzal AR, Rajab A, Fenske CD, Oldridge M, Elanko N, et al. (2000) Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2. Nat Genet 25: 419-422.
-
(2000)
Nat Genet
, vol.25
, pp. 419-422
-
-
Afzal, A.R.1
Rajab, A.2
Fenske, C.D.3
Oldridge, M.4
Elanko, N.5
-
10
-
-
42949121156
-
Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
-
Fukuda T, Chen L, Endo T, Tang L, Lu D, et al. (2008) Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a. Proc Natl Acad Sci U S A 105: 3047-3052.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3047-3052
-
-
Fukuda, T.1
Chen, L.2
Endo, T.3
Tang, L.4
Lu, D.5
-
11
-
-
0034009511
-
Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B
-
Oldridge M, Fortuna AM, Maringa M, Propping P, Mansour S, et al. (2000) Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B. Nat Genet 24: 275-278.
-
(2000)
Nat Genet
, vol.24
, pp. 275-278
-
-
Oldridge, M.1
Fortuna, A.M.2
Maringa, M.3
Propping, P.4
Mansour, S.5
-
12
-
-
42449110211
-
Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia
-
Shabani M, Asgarian-Omran H, Jeddi-Tehrani M, Vossough P, Faranoush M, et al. (2007) Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia. Tumour Biol 28: 318-326.
-
(2007)
Tumour Biol
, vol.28
, pp. 318-326
-
-
Shabani, M.1
Asgarian-Omran, H.2
Jeddi-Tehrani, M.3
Vossough, P.4
Faranoush, M.5
-
13
-
-
38949156617
-
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia
-
Baskar S, Kwong KY, Hofer T, Levy JM, Kennedy MG, et al. (2008) Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia. Clin Cancer Res 14: 396-404.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 396-404
-
-
Baskar, S.1
Kwong, K.Y.2
Hofer, T.3
Levy, J.M.4
Kennedy, M.G.5
-
14
-
-
47249140824
-
Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy
-
Daneshmanesh AH, Mikaelsson E, Jeddi-Tehrani M, Bayat AA, Ghods R, et al. (2008) Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy. Int J Cancer 123: 1190-1195.
-
(2008)
Int J Cancer
, vol.123
, pp. 1190-1195
-
-
Daneshmanesh, A.H.1
Mikaelsson, E.2
Jeddi-Tehrani, M.3
Bayat, A.A.4
Ghods, R.5
-
15
-
-
66649137944
-
RNAi screen for rapid therapeutic target identification in leukemia patients
-
Tyner JW, Deininger MW, Loriaux MM, Chang BH, Gotlib JR, et al. (2009) RNAi screen for rapid therapeutic target identification in leukemia patients. Proc Natl Acad Sci U S A 106: 8695-8700.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8695-8700
-
-
Tyner, J.W.1
Deininger, M.W.2
Loriaux, M.M.3
Chang, B.H.4
Gotlib, J.R.5
-
16
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
MacKeigan JP, Murphy LO, Blenis J, (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat Cell Biol 7: 591-600.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 591-600
-
-
MacKeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
17
-
-
77958519836
-
Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells
-
Choudhury A, Derkow K, Daneshmanesh AH, Mikaelsson E, Kiaii S, et al. (2010) Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells. Br J Haematol.
-
(2010)
Br J Haematol
-
-
Choudhury, A.1
Derkow, K.2
Daneshmanesh, A.H.3
Mikaelsson, E.4
Kiaii, S.5
-
18
-
-
79954622199
-
Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis
-
Gentile A, Lazzari L, Benvenuti S, Trusolino L, Comoglio PM, (2011) Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis. Cancer Res 71: 3132-3141.
-
(2011)
Cancer Res
, vol.71
, pp. 3132-3141
-
-
Gentile, A.1
Lazzari, L.2
Benvenuti, S.3
Trusolino, L.4
Comoglio, P.M.5
-
19
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10: 515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
-
20
-
-
33749030177
-
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer
-
Hess KR, Anderson K, Symmans WF, Valero V, Ibrahim N, et al. (2006) Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol 24: 4236-4244.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4236-4244
-
-
Hess, K.R.1
Anderson, K.2
Symmans, W.F.3
Valero, V.4
Ibrahim, N.5
-
21
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347: 1999-2009.
-
(2002)
N Engl J Med
, vol.347
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
van't Veer, L.J.3
Dai, H.4
Hart, A.A.5
-
22
-
-
22044434887
-
Human adaptive immune system Rag2-/-gamma(c)-/- mice
-
Chicha L, Tussiwand R, Traggiai E, Mazzucchelli L, Bronz L, et al. (2005) Human adaptive immune system Rag2-/-gamma(c)-/- mice. Ann N Y Acad Sci 1044: 236-243.
-
(2005)
Ann N Y Acad Sci
, vol.1044
, pp. 236-243
-
-
Chicha, L.1
Tussiwand, R.2
Traggiai, E.3
Mazzucchelli, L.4
Bronz, L.5
-
23
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, et al. (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34: 267-273.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
-
24
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van 't Veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
-
25
-
-
0035430282
-
Transcriptional regulation by the phosphorylation-dependent factor CREB
-
Mayr B, Montminy M, (2001) Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2: 599-609.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 599-609
-
-
Mayr, B.1
Montminy, M.2
-
26
-
-
0032484019
-
CREB is a regulatory target for the protein kinase Akt/PKB
-
Du K, Montminy M, (1998) CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem 273: 32377-32379.
-
(1998)
J Biol Chem
, vol.273
, pp. 32377-32379
-
-
Du, K.1
Montminy, M.2
-
27
-
-
9644290911
-
The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon
-
Kani S, Oishi I, Yamamoto H, Yoda A, Suzuki H, et al. (2004) The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon. J Biol Chem 279: 50102-50109.
-
(2004)
J Biol Chem
, vol.279
, pp. 50102-50109
-
-
Kani, S.1
Oishi, I.2
Yamamoto, H.3
Yoda, A.4
Suzuki, H.5
-
28
-
-
39749109323
-
Casein Kinase I epsilon positively regulates the Akt pathway in breast cancer cell lines
-
Modak C, Bryant P, (2008) Casein Kinase I epsilon positively regulates the Akt pathway in breast cancer cell lines. Biochem Biophys Res Commun 368: 801-807.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 801-807
-
-
Modak, C.1
Bryant, P.2
-
29
-
-
33846266252
-
Prognostic markers in triple-negative breast cancer
-
Rakha EA, El-Sayed ME, Green AR, Lee AH, Robertson JF, et al. (2007) Prognostic markers in triple-negative breast cancer. Cancer 109: 25-32.
-
(2007)
Cancer
, vol.109
, pp. 25-32
-
-
Rakha, E.A.1
El-Sayed, M.E.2
Green, A.R.3
Lee, A.H.4
Robertson, J.F.5
-
30
-
-
0016755280
-
Current status of estrogen receptors in human breast cancer
-
McGuire WL, (1975) Current status of estrogen receptors in human breast cancer. Cancer 36: 638-644.
-
(1975)
Cancer
, vol.36
, pp. 638-644
-
-
McGuire, W.L.1
-
31
-
-
0018377490
-
Endocrine therapy in cancer
-
Stoll BA, (1979) Endocrine therapy in cancer. Practitioner 222: 211-217.
-
(1979)
Practitioner
, vol.222
, pp. 211-217
-
-
Stoll, B.A.1
-
32
-
-
39449095439
-
Growth suppression of lung cancer cells by targeting cyclic AMP response element-binding protein
-
Aggarwal S, Kim SW, Ryu SH, Chung WC, Koo JS, (2008) Growth suppression of lung cancer cells by targeting cyclic AMP response element-binding protein. Cancer Res 68: 981-988.
-
(2008)
Cancer Res
, vol.68
, pp. 981-988
-
-
Aggarwal, S.1
Kim, S.W.2
Ryu, S.H.3
Chung, W.C.4
Koo, J.S.5
-
33
-
-
38949210725
-
CREB is a critical regulator of normal hematopoiesis and leukemogenesis
-
Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, et al. (2008) CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Blood 111: 1182-1192.
-
(2008)
Blood
, vol.111
, pp. 1182-1192
-
-
Cheng, J.C.1
Kinjo, K.2
Judelson, D.R.3
Chang, J.4
Wu, W.S.5
-
34
-
-
38449107066
-
Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis
-
Chhabra A, Fernando H, Watkins G, Mansel RE, Jiang WG, (2007) Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis. Oncol Rep 18: 953-958.
-
(2007)
Oncol Rep
, vol.18
, pp. 953-958
-
-
Chhabra, A.1
Fernando, H.2
Watkins, G.3
Mansel, R.E.4
Jiang, W.G.5
-
35
-
-
55949122454
-
cAMP response element-binding protein is expressed at high levels in human ovarian adenocarcinoma and regulates ovarian tumor cell proliferation
-
Linnerth NM, Greenaway JB, Petrik JJ, Moorehead RA, (2008) cAMP response element-binding protein is expressed at high levels in human ovarian adenocarcinoma and regulates ovarian tumor cell proliferation. Int J Gynecol Cancer 18: 1248-1257.
-
(2008)
Int J Gynecol Cancer
, vol.18
, pp. 1248-1257
-
-
Linnerth, N.M.1
Greenaway, J.B.2
Petrik, J.J.3
Moorehead, R.A.4
-
36
-
-
65249140538
-
CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy
-
Sakamoto KM, Frank DA, (2009) CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy. Clin Cancer Res 15: 2583-2587.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2583-2587
-
-
Sakamoto, K.M.1
Frank, D.A.2
-
37
-
-
77953662351
-
Targeting CREB for cancer therapy: friend or foe
-
Xiao X, Li BX, Mitton B, Ikeda A, Sakamoto KM, (2010) Targeting CREB for cancer therapy: friend or foe. Curr Cancer Drug Targets 10: 384-391.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 384-391
-
-
Xiao, X.1
Li, B.X.2
Mitton, B.3
Ikeda, A.4
Sakamoto, K.M.5
-
38
-
-
20144379523
-
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
-
Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, et al. (2005) Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A 102: 4459-4464.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4459-4464
-
-
Zhang, X.1
Odom, D.T.2
Koo, S.H.3
Conkright, M.D.4
Canettieri, G.5
-
39
-
-
47349125915
-
Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest
-
Yang WS, Stockwell BR, (2008) Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest. Genome Biol 9: R92.
-
(2008)
Genome Biol
, vol.9
-
-
Yang, W.S.1
Stockwell, B.R.2
-
40
-
-
1542267803
-
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
-
Lu D, Zhao Y, Tawatao R, Cottam HB, Sen M, et al. (2004) Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 101: 3118-3123.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3118-3123
-
-
Lu, D.1
Zhao, Y.2
Tawatao, R.3
Cottam, H.B.4
Sen, M.5
-
41
-
-
33645774667
-
Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
-
Pukrop T, Klemm F, Hagemann T, Gradl D, Schulz M, et al. (2006) Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. Proc Natl Acad Sci U S A 103: 5454-5459.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5454-5459
-
-
Pukrop, T.1
Klemm, F.2
Hagemann, T.3
Gradl, D.4
Schulz, M.5
-
42
-
-
0029096787
-
Aberrant expression of the growth factor Wnt-5A in human malignancy
-
Iozzo RV, Eichstetter I, Danielson KG, (1995) Aberrant expression of the growth factor Wnt-5A in human malignancy. Cancer Res 55: 3495-3499.
-
(1995)
Cancer Res
, vol.55
, pp. 3495-3499
-
-
Iozzo, R.V.1
Eichstetter, I.2
Danielson, K.G.3
-
43
-
-
0028902359
-
Wnt5a cloning, expression, and up-regulation in human primary breast cancers
-
Lejeune S, Huguet EL, Hamby A, Poulsom R, Harris AL, (1995) Wnt5a cloning, expression, and up-regulation in human primary breast cancers. Clin Cancer Res 1: 215-222.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 215-222
-
-
Lejeune, S.1
Huguet, E.L.2
Hamby, A.3
Poulsom, R.4
Harris, A.L.5
-
44
-
-
85047690674
-
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
-
Sun CX, Young HW, Molina JG, Volmer JB, Schnermann J, et al. (2005) A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury. J Clin Invest 115: 35-43.
-
(2005)
J Clin Invest
, vol.115
, pp. 35-43
-
-
Sun, C.X.1
Young, H.W.2
Molina, J.G.3
Volmer, J.B.4
Schnermann, J.5
|