메뉴 건너뛰기




Volumn 210, Issue 2, 2015, Pages 191-208

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; APHIDICOLIN; BLOOM SYNDROME HELICASE; GUANINE QUADRUPLEX; WERNER SYNDROME PROTEIN; RECQ HELICASE; WERNER SYNDROME ATP DEPENDENT HELICASE; WRN PROTEIN, MOUSE;

EID: 84957615695     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201410061     Document Type: Article
Times cited : (125)

References (59)
  • 1
    • 79952127438 scopus 로고    scopus 로고
    • Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
    • Aggarwal, M., J.A. Sommers, R.H. Shoemaker, and R.M. Brosh Jr. 2011. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress. Proc. Natl. Acad. Sci. USA. 108:1525-1530. http://dx.doi.org/10.1073/pnas.1006423108.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 1525-1530
    • Aggarwal, M.1    Sommers, J.A.2    Shoemaker, R.H.3    Brosh, R.M.4
  • 2
    • 84867304481 scopus 로고    scopus 로고
    • The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures
    • Barefield, C., and J. Karlseder. 2012. The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures. Nucleic Acids Res. 40:7358-7367. http://dx.doi.org/10.1093/nar/gks407.
    • (2012) Nucleic Acids Res , vol.40 , pp. 7358-7367
    • Barefield, C.1    Karlseder, J.2
  • 3
    • 84875464903 scopus 로고    scopus 로고
    • Quantitative visualization of DNA G-quadruplex structures in human cells
    • Biffi, G., D. Tannahill, J. McCafferty, and S. Balasubramanian. 2013. Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem. 5:182-186. http://dx.doi.org/10.1038/nchem.1548.
    • (2013) Nat. Chem , vol.5 , pp. 182-186
    • Biffi, G.1    Tannahill, D.2    McCafferty, J.3    Balasubramanian, S.4
  • 4
    • 84890958553 scopus 로고    scopus 로고
    • Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
    • Biffi, G., M. Di Antonio, D. Tannahill, and S. Balasubramanian. 2014. Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat. Chem. 6:75-80. http://dx.doi.org/10.1038/nchem.1805.
    • (2014) Nat. Chem , vol.6 , pp. 75-80
    • Biffi, G.1    Di Antonio, M.2    Tannahill, D.3    Balasubramanian, S.4
  • 5
    • 33751020853 scopus 로고    scopus 로고
    • Quadruplex DNA: sequence, topology and structure
    • Burge, S., G.N. Parkinson, P. Hazel, A.K. Todd, and S. Neidle. 2006. Quadruplex DNA: sequence, topology and structure. Nucleic Acids Res. 34:5402-5415. http://dx.doi.org/10.1093/nar/gkl655.
    • (2006) Nucleic Acids Res , vol.34 , pp. 5402-5415
    • Burge, S.1    Parkinson, G.N.2    Hazel, P.3    Todd, A.K.4    Neidle, S.5
  • 6
    • 18244371925 scopus 로고    scopus 로고
    • Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
    • Byun, T.S., M. Pacek, M.C. Yee, J.C. Walter, and K.A. Cimprich. 2005. Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev. 19:1040-1052. http://dx.doi.org/10.1101/gad.1301205.
    • (2005) Genes Dev , vol.19 , pp. 1040-1052
    • Byun, T.S.1    Pacek, M.2    Yee, M.C.3    Walter, J.C.4    Cimprich, K.A.5
  • 7
    • 34547192058 scopus 로고    scopus 로고
    • BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
    • Chan, K.L., P.S. North, and I.D. Hickson. 2007. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J. 26:3397-3409. http://dx.doi.org/10.1038/sj.emboj.7601777.
    • (2007) EMBO J , vol.26 , pp. 3397-3409
    • Chan, K.L.1    North, P.S.2    Hickson, I.D.3
  • 8
    • 64249134709 scopus 로고    scopus 로고
    • Telomeres do the (un)twist: helicase actions at chromosome termini
    • Chavez, A., A.M. Tsou, and F.B. Johnson. 2009. Telomeres do the (un)twist: helicase actions at chromosome termini. Biochim. Biophys. Acta. 1792:329-340. http://dx.doi.org/10.1016/j.bbadis.2009.02.008.
    • (2009) Biochim. Biophys. Acta , vol.1792 , pp. 329-340
    • Chavez, A.1    Tsou, A.M.2    Johnson, F.B.3
  • 9
    • 84893255474 scopus 로고    scopus 로고
    • Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)
    • Chung, W.J., B. Heddi, F. Hamon, M.P. Teulade-Fichou, and A.T. Phan. 2014. Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3). Angew. Chem. Int. Ed. Engl. 53:999-1002. http://dx.doi.org/10.1002/anie.201308063.
    • (2014) Angew. Chem. Int. Ed. Engl , vol.53 , pp. 999-1002
    • Chung, W.J.1    Heddi, B.2    Hamon, F.3    Teulade-Fichou, M.P.4    Phan, A.T.5
  • 10
    • 34547814092 scopus 로고    scopus 로고
    • Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells
    • Conti, C., B. Saccà, J. Herrick, C. Lalou, Y. Pommier, and A. Bensimon. 2007. Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells. Mol. Biol. Cell. 18:3059-3067. http://dx.doi.org/10.1091/mbc. E06-08-0689.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3059-3067
    • Conti, C.1    Saccà, B.2    Herrick, J.3    Lalou, C.4    Pommier, Y.5    Bensimon, A.6
  • 11
    • 52949092763 scopus 로고    scopus 로고
    • Replication fork movement sets chromatin loop size and origin choice in mammalian cells
    • Courbet, S., S. Gay, N. Arnoult, G. Wronka, M. Anglana, O. Brison, and M. Debatisse. 2008. Replication fork movement sets chromatin loop size and origin choice in mammalian cells. Nature. 455:557-560. http://dx.doi.org/10.1038/nature07233.
    • (2008) Nature , vol.455 , pp. 557-560
    • Courbet, S.1    Gay, S.2    Arnoult, N.3    Wronka, G.4    Anglana, M.5    Brison, O.6    Debatisse, M.7
  • 12
    • 10344256183 scopus 로고    scopus 로고
    • Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
    • Crabbe, L., R.E. Verdun, C.I. Haggblom, and J. Karlseder. 2004. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science. 306:1951-1953. http://dx.doi.org/10.1126/science.1103619.
    • (2004) Science , vol.306 , pp. 1951-1953
    • Crabbe, L.1    Verdun, R.E.2    Haggblom, C.I.3    Karlseder, J.4
  • 13
    • 84902187810 scopus 로고    scopus 로고
    • Human RecQ helicases in DNA repair, recombination, and replication
    • Croteau, D.L., V. Popuri, P.L. Opresko, and V.A. Bohr. 2014. Human RecQ helicases in DNA repair, recombination, and replication. Annu. Rev. Biochem. 83:519-552. http://dx.doi.org/10.1146/annurev-biochem-060713-035428.
    • (2014) Annu. Rev. Biochem , vol.83 , pp. 519-552
    • Croteau, D.L.1    Popuri, V.2    Opresko, P.L.3    Bohr, V.A.4
  • 15
    • 33847294223 scopus 로고    scopus 로고
    • Highly efficient G-quadruplex recognition by bisquinolinium compounds
    • De Cian, A., E. Delemos, J.L. Mergny, M.P. Teulade-Fichou, and D. Monchaud. 2007b. Highly efficient G-quadruplex recognition by bisquinolinium compounds. J. Am. Chem. Soc. 129:1856-1857. http://dx.doi.org/10.1021/ja067352b.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 1856-1857
    • De Cian, A.1    Delemos, E.2    Mergny, J.L.3    Teulade-Fichou, M.P.4    Monchaud, D.5
  • 16
    • 58149085861 scopus 로고    scopus 로고
    • Purification of proteins associated with specific genomic Loci
    • Déjardin, J., and R.E. Kingston. 2009. Purification of proteins associated with specific genomic Loci. Cell. 136:175-186. http://dx.doi.org/10.1016/j.cell.2008.11.045.
    • (2009) Cell , vol.136 , pp. 175-186
    • Déjardin, J.1    Kingston, R.E.2
  • 17
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • de Lange, T. 2005. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19:2100-2110. http://dx.doi.org/10.1101/gad.1346005.
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 18
    • 84885580087 scopus 로고    scopus 로고
    • Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation
    • Doksani, Y., J.Y. Wu, T. de Lange, and X. Zhuang. 2013. Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation. Cell. 155:345-356. http://dx.doi.org/10.1016/j.cell.2013.09.048.
    • (2013) Cell , vol.155 , pp. 345-356
    • Doksani, Y.1    Wu, J.Y.2    de Lange, T.3    Zhuang, X.4
  • 19
    • 84861933930 scopus 로고    scopus 로고
    • Human telomeres replicate using chromosome-specific, rather than universal, replication programs
    • Drosopoulos, W.C., S.T. Kosiyatrakul, Z. Yan, S.G. Calderano, and C.L. Schildkraut. 2012. Human telomeres replicate using chromosome-specific, rather than universal, replication programs. J. Cell Biol. 197:253-266. http://dx.doi.org/10.1083/jcb.201112083.
    • (2012) J. Cell Biol , vol.197 , pp. 253-266
    • Drosopoulos, W.C.1    Kosiyatrakul, S.T.2    Yan, Z.3    Calderano, S.G.4    Schildkraut, C.L.5
  • 21
    • 0033617316 scopus 로고    scopus 로고
    • Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n
    • Fry, M., and L.A. Loeb. 1999. Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. J. Biol. Chem. 274:12797-12802. http://dx.doi.org/10.1074/jbc.274.18.12797.
    • (1999) J. Biol. Chem , vol.274 , pp. 12797-12802
    • Fry, M.1    Loeb, L.A.2
  • 22
    • 34648843213 scopus 로고    scopus 로고
    • How telomeres are replicated
    • Gilson, E., and V. Géli. 2007. How telomeres are replicated. Nat. Rev. Mol. Cell Biol. 8:825-838. http://dx.doi.org/10.1038/nrm2259.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 825-838
    • Gilson, E.1    Géli, V.2
  • 25
    • 3142546346 scopus 로고
    • A retarded rate of DNA chain growth in Bloom's syndrome
    • Hand, R., and J. German. 1975. A retarded rate of DNA chain growth in Bloom's syndrome. Proc. Natl. Acad. Sci. USA. 72:758-762. http://dx.doi.org/10.1073/pnas.72.2.758.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 758-762
    • Hand, R.1    German, J.2
  • 27
    • 77950353700 scopus 로고    scopus 로고
    • Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
    • Johnson, J.E., K. Cao, P. Ryvkin, L.S. Wang, and F.B. Johnson. 2010. Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential. Nucleic Acids Res. 38:1114-1122. http://dx.doi.org/10.1093/nar/gkp1103.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1114-1122
    • Johnson, J.E.1    Cao, K.2    Ryvkin, P.3    Wang, L.S.4    Johnson, F.B.5
  • 29
    • 0027303982 scopus 로고
    • A general protocol for evaluating the specific effects of DNA replication inhibitors
    • Levenson, V., and J.L. Hamlin. 1993. A general protocol for evaluating the specific effects of DNA replication inhibitors. Nucleic Acids Res. 21:3997-4004. http://dx.doi.org/10.1093/nar/21.17.3997.
    • (1993) Nucleic Acids Res , vol.21 , pp. 3997-4004
    • Levenson, V.1    Hamlin, J.L.2
  • 35
    • 33751581731 scopus 로고    scopus 로고
    • The Werner and Bloom syndrome proteins catalyze regression of a model replication fork
    • Machwe, A., L. Xiao, J. Groden, and D.K. Orren. 2006. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry. 45:13939-13946. http://dx.doi.org/10.1021/bi0615487.
    • (2006) Biochemistry , vol.45 , pp. 13939-13946
    • Machwe, A.1    Xiao, L.2    Groden, J.3    Orren, D.K.4
  • 36
    • 80051512519 scopus 로고    scopus 로고
    • The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks
    • Machwe, A., R. Karale, X. Xu, Y. Liu, and D.K. Orren. 2011. The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks. Biochemistry. 50:6774-6788. http://dx.doi.org/10.1021/bi2001054.
    • (2011) Biochemistry , vol.50 , pp. 6774-6788
    • Machwe, A.1    Karale, R.2    Xu, X.3    Liu, Y.4    Orren, D.K.5
  • 37
    • 84876862930 scopus 로고    scopus 로고
    • The G4 genome
    • Maizels, N., and L.T. Gray. 2013. The G4 genome. PLoS Genet. 9:e1003468. http://dx.doi.org/10.1371/journal.pgen.1003468.
    • (2013) PLoS Genet , vol.9
    • Maizels, N.1    Gray, L.T.2
  • 38
  • 39
    • 0345724846 scopus 로고    scopus 로고
    • Chromosome instability and tumor predisposition inversely correlate with BLM protein levels
    • McDaniel, L.D., N. Chester, M. Watson, A.D. Borowsky, P. Leder, and R.A. Schultz. 2003. Chromosome instability and tumor predisposition inversely correlate with BLM protein levels. DNA Repair (Amst.). 2:1387-1404. http://dx.doi.org/10.1016/j.dnarep.2003.08.006.
    • (2003) DNA Repair (Amst.) , vol.2 , pp. 1387-1404
    • McDaniel, L.D.1    Chester, N.2    Watson, M.3    Borowsky, A.D.4    Leder, P.5    Schultz, R.A.6
  • 40
    • 0035393720 scopus 로고    scopus 로고
    • The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
    • Mohaghegh, P., J.K. Karow, R.M. Brosh Jr., V.A. Bohr, and I.D. Hickson. 2001. The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res. 29:2843-2849. http://dx.doi.org/10.1093/nar/29.13.2843.
    • (2001) Nucleic Acids Res , vol.29 , pp. 2843-2849
    • Mohaghegh, P.1    Karow, J.K.2    Brosh, R.M.3    Bohr, V.A.4    Hickson, I.D.5
  • 41
    • 47849126383 scopus 로고    scopus 로고
    • Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders
    • Monchaud, D., C. Allain, H. Bertrand, N. Smargiasso, F. Rosu, V. Gabelica, A. De Cian, J.L. Mergny, and M.P. Teulade-Fichou. 2008. Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders. Biochimie. 90:1207-1223. http://dx.doi.org/10.1016/j.biochi.2008.02.019.
    • (2008) Biochimie , vol.90 , pp. 1207-1223
    • Monchaud, D.1    Allain, C.2    Bertrand, H.3    Smargiasso, N.4    Rosu, F.5    Gabelica, V.6    De Cian, A.7    Mergny, J.L.8    Teulade-Fichou, M.P.9
  • 43
    • 0035861512 scopus 로고    scopus 로고
    • Visualization of DNA replication on individual Epstein-Barr virus episomes
    • Norio, P., and C.L. Schildkraut. 2001. Visualization of DNA replication on individual Epstein-Barr virus episomes. Science. 294:2361-2364. http://dx.doi.org/10.1126/science.1064603.
    • (2001) Science , vol.294 , pp. 2361-2364
    • Norio, P.1    Schildkraut, C.L.2
  • 44
    • 16644394727 scopus 로고    scopus 로고
    • Plasticity of DNA replication initiation in Epstein-Barr virus episomes
    • Norio, P., and C.L. Schildkraut. 2004. Plasticity of DNA replication initiation in Epstein-Barr virus episomes. PLoS Biol. 2:e152. http://dx.doi.org/10.1371/journal.pbio.0020152.
    • (2004) PLoS Biol , vol.2
    • Norio, P.1    Schildkraut, C.L.2
  • 45
    • 27944452746 scopus 로고    scopus 로고
    • Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development
    • Norio, P., S. Kosiyatrakul, Q. Yang, Z. Guan, N.M. Brown, S. Thomas, R. Riblet, and C.L. Schildkraut. 2005. Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development. Mol. Cell. 20:575-587. http://dx.doi.org/10.1016/j.molcel.2005.10.029.
    • (2005) Mol. Cell , vol.20 , pp. 575-587
    • Norio, P.1    Kosiyatrakul, S.2    Yang, Q.3    Guan, Z.4    Brown, N.M.5    Thomas, S.6    Riblet, R.7    Schildkraut, C.L.8
  • 46
    • 38949094875 scopus 로고    scopus 로고
    • Telomere ResQue and preservation-roles for the Werner syndrome protein and other RecQ helicases
    • Opresko, P.L. 2008. Telomere ResQue and preservation-roles for the Werner syndrome protein and other RecQ helicases. Mech. Ageing Dev. 129:79-90. http://dx.doi.org/10.1016/j.mad.2007.10.007.
    • (2008) Mech. Ageing Dev , vol.129 , pp. 79-90
    • Opresko, P.L.1
  • 47
    • 0037175018 scopus 로고    scopus 로고
    • Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
    • Opresko, P.L., C. von Kobbe, J.P. Laine, J. Harrigan, I.D. Hickson, and V.A. Bohr. 2002. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem. 277:41110-41119. http://dx.doi.org/10.1074/jbc. M205396200.
    • (2002) J. Biol. Chem , vol.277 , pp. 41110-41119
    • Opresko, P.L.1    von Kobbe, C.2    Laine, J.P.3    Harrigan, J.4    Hickson, I.D.5    Bohr, V.A.6
  • 48
    • 25444533047 scopus 로고    scopus 로고
    • POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
    • Opresko, P.L., P.A. Mason, E.R. Podell, M. Lei, I.D. Hickson, T.R. Cech, and V.A. Bohr. 2005. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. J. Biol. Chem. 280:32069-32080. http://dx.doi.org/10.1074/jbc. M505211200.
    • (2005) J. Biol. Chem , vol.280 , pp. 32069-32080
    • Opresko, P.L.1    Mason, P.A.2    Podell, E.R.3    Lei, M.4    Hickson, I.D.5    Cech, T.R.6    Bohr, V.A.7
  • 49
    • 32444450705 scopus 로고    scopus 로고
    • Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication
    • Pacek, M., A.V. Tutter, Y. Kubota, H. Takisawa, and J.C. Walter. 2006. Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol. Cell. 21:581-587. http://dx.doi.org/10.1016/j.molcel.2006.01.030.
    • (2006) Mol. Cell , vol.21 , pp. 581-587
    • Pacek, M.1    Tutter, A.V.2    Kubota, Y.3    Takisawa, H.4    Walter, J.C.5
  • 50
    • 77955253773 scopus 로고    scopus 로고
    • Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae
    • Piazza, A., J.B. Boulé, J. Lopes, K. Mingo, E. Largy, M.P. Teulade-Fichou, and A. Nicolas. 2010. Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae. Nucleic Acids Res. 38:4337-4348. http://dx.doi.org/10.1093/nar/gkq136.
    • (2010) Nucleic Acids Res , vol.38 , pp. 4337-4348
    • Piazza, A.1    Boulé, J.B.2    Lopes, J.3    Mingo, K.4    Largy, E.5    Teulade-Fichou, M.P.6    Nicolas, A.7
  • 51
    • 33747352774 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase can promote the regression of a model replication fork
    • Ralf, C., I.D. Hickson, and L. Wu. 2006. The Bloom's syndrome helicase can promote the regression of a model replication fork. J. Biol. Chem. 281:22839-22846. http://dx.doi.org/10.1074/jbc. M604268200.
    • (2006) J. Biol. Chem , vol.281 , pp. 22839-22846
    • Ralf, C.1    Hickson, I.D.2    Wu, L.3
  • 52
    • 34547132330 scopus 로고    scopus 로고
    • Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks
    • Rao, V.A., C. Conti, J. Guirouilh-Barbat, A. Nakamura, Z.H. Miao, S.L. Davies, B. Saccá, I.D. Hickson, A. Bensimon, and Y. Pommier. 2007. Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks. Mol. Cancer Res. 5:713-724. http://dx.doi.org/10.1158/1541-7786.MCR-07-0028.
    • (2007) Mol. Cancer Res , vol.5 , pp. 713-724
    • Rao, V.A.1    Conti, C.2    Guirouilh-Barbat, J.3    Nakamura, A.4    Miao, Z.H.5    Davies, S.L.6    Saccá, B.7    Hickson, I.D.8    Bensimon, A.9    Pommier, Y.10
  • 53
    • 84857818879 scopus 로고    scopus 로고
    • FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA
    • Sarkies, P., P. Murat, L.G. Phillips, K.J. Patel, S. Balasubramanian, and J.E. Sale. 2012. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res. 40:1485-1498. http://dx.doi.org/10.1093/nar/gkr868.
    • (2012) Nucleic Acids Res , vol.40 , pp. 1485-1498
    • Sarkies, P.1    Murat, P.2    Phillips, L.G.3    Patel, K.J.4    Balasubramanian, S.5    Sale, J.E.6
  • 55
    • 67649635974 scopus 로고    scopus 로고
    • Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
    • Sfeir, A., S.T. Kosiyatrakul, D. Hockemeyer, S.L. MacRae, J. Karlseder, C.L. Schildkraut, and T. de Lange. 2009. Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell. 138:90-103. http://dx.doi.org/10.1016/j.cell.2009.06.021.
    • (2009) Cell , vol.138 , pp. 90-103
    • Sfeir, A.1    Kosiyatrakul, S.T.2    Hockemeyer, D.3    MacRae, S.L.4    Karlseder, J.5    Schildkraut, C.L.6    de Lange, T.7
  • 56
    • 84864499620 scopus 로고    scopus 로고
    • RecQ helicases in DNA double strand break repair and telomere maintenance
    • Singh, D.K., A.K. Ghosh, D.L. Croteau, and V.A. Bohr. 2012. RecQ helicases in DNA double strand break repair and telomere maintenance. Mutat. Res. 736:15-24. http://dx.doi.org/10.1016/j.mrfmmm.2011.06.002.
    • (2012) Mutat. Res , vol.736 , pp. 15-24
    • Singh, D.K.1    Ghosh, A.K.2    Croteau, D.L.3    Bohr, V.A.4
  • 57
  • 59
    • 44949114282 scopus 로고    scopus 로고
    • FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability
    • Wu, Y., K. Shin-ya, and R.M. Brosh Jr. 2008. FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. Mol. Cell. Biol. 28:4116-4128. http://dx.doi.org/10.1128/MCB.02210-07.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 4116-4128
    • Wu, Y.1    Shin-ya, K.2    Brosh, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.