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Volumn 2, Issue 12, 2003, Pages 1387-1404

Chromosome instability and tumor predisposition inversely correlate with BLM protein levels

Author keywords

Blm protein; Bloom syndrome; Cancer; Chromosome instability; Hypomorph

Indexed keywords

PROTEIN; PROTEIN BLM; UNCLASSIFIED DRUG;

EID: 0345724846     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2003.08.006     Document Type: Article
Times cited : (47)

References (38)
  • 1
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome
    • Chaganti R.S., Schonberg S., German J. A manyfold increase in sister chromatid exchanges in Bloom's syndrome. Proc. Natl. Acad. Sci. U.S.A. 71:1974;4508-4512.
    • (1974) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 4508-4512
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 2
    • 0018291116 scopus 로고
    • Sister chromatid exchange and cell cycle in fibroblasts of Bloom's syndrome
    • Brat S.V. Sister chromatid exchange and cell cycle in fibroblasts of Bloom's syndrome. Hum. Genet. 48:1979;73-79.
    • (1979) Hum. Genet. , vol.48 , pp. 73-79
    • Brat, S.V.1
  • 3
  • 4
    • 0032547953 scopus 로고    scopus 로고
    • Point mutations causing Bloom's syndrome abolish atpase and DNA helicase activities of the blm protein
    • Bahr A., De Graeve F., Kedinger C., Chatton B. Point mutations causing Bloom's syndrome abolish atpase and DNA helicase activities of the blm protein. Oncogene. 17:1998;2565-2571.
    • (1998) Oncogene , vol.17 , pp. 2565-2571
    • Bahr, A.1    De Graeve, F.2    Kedinger, C.3    Chatton, B.4
  • 5
    • 0028033989 scopus 로고
    • The yeast type i topoisomerase top3 interacts with sgs1, a DNA helicase homolog: A potential eukaryotic reverse gyrase
    • Gangloff S., McDonald J.P., Bendixen C., Arthur L., Rothstein R. The yeast type i topoisomerase top3 interacts with sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14:1994;8391-8398.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8391-8398
    • Gangloff, S.1    McDonald, J.P.2    Bendixen, C.3    Arthur, L.4    Rothstein, R.5
  • 6
    • 0033031935 scopus 로고    scopus 로고
    • Recq helicase and topoisomerase iii comprise a novel DNA strand passage function: A conserved mechanism for control of DNA recombination
    • Harmon F.G., DiGate R.J., Kowalczykowski S.C. Recq helicase and topoisomerase iii comprise a novel DNA strand passage function: a conserved mechanism for control of DNA recombination. Mol. Cell. 3:1999;611-620.
    • (1999) Mol. Cell , vol.3 , pp. 611-620
    • Harmon, F.G.1    Digate, R.J.2    Kowalczykowski, S.C.3
  • 8
    • 0030686496 scopus 로고    scopus 로고
    • The Bloom's syndrome gene product is a 3′-5′ DNA helicase
    • Karow J.K., Chakraverty R.K., Hickson I.D. The Bloom's syndrome gene product is a 3′-5′ DNA helicase. J. Biol. Chem. 272:1997;30611- 30614.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30611-30614
    • Karow, J.K.1    Chakraverty, R.K.2    Hickson, I.D.3
  • 9
    • 0035909817 scopus 로고    scopus 로고
    • Inhibition of the Bloom's and Werner's syndrome helicases by g-quadruplex interacting ligands
    • Li J.L., Harrison R.J., Reszka A.P., Brosh R.M., Bohr V.A., Neidle S., Hickson I.D. Inhibition of the Bloom's and Werner's syndrome helicases by g-quadruplex interacting ligands. Biochemistry. 40:2001;15194-15202.
    • (2001) Biochemistry , vol.40 , pp. 15194-15202
    • Li, J.L.1    Harrison, R.J.2    Reszka, A.P.3    Brosh, R.M.4    Bohr, V.A.5    Neidle, S.6    Hickson, I.D.7
  • 12
    • 0035857043 scopus 로고    scopus 로고
    • The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control
    • Garkavtsev I.V., Kley N., Grigorian I.A., Gudkov A.V. The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control. Oncogene. 20:2001;8276-8280.
    • (2001) Oncogene , vol.20 , pp. 8276-8280
    • Garkavtsev, I.V.1    Kley, N.2    Grigorian, I.A.3    Gudkov, A.V.4
  • 13
    • 0034655991 scopus 로고    scopus 로고
    • Basc, a super complex of brca1-associated proteins involved in the recognition and repair of aberrant DNA structures
    • Y. Wang, D. Cortez, P. Yazdi, N. Neff, S.J. Elledge, J. Qin Basc, a super complex of brca1-associated proteins involved in the recognition and repair of aberrant DNA structures, Gen. Dev. (2000) 8.
    • (2000) Gen. Dev. , pp. 8
    • Wang, Y.1    Cortez, D.2    Yazdi, P.3    Neff, N.4    Elledge, S.J.5    Qin, J.6
  • 14
    • 0036797833 scopus 로고    scopus 로고
    • Protecting genomic integrity during DNA replication: Correlation between Werner's and Bloom's syndrome gene products and the mre11 complex
    • Franchitto A., Pichierri P. Protecting genomic integrity during DNA replication: correlation between Werner's and Bloom's syndrome gene products and the mre11 complex. Hum. Mol. Genet. 11:2002;2447-2453.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2447-2453
    • Franchitto, A.1    Pichierri, P.2
  • 16
    • 0032213939 scopus 로고    scopus 로고
    • Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene
    • Chester N., Kuo F., Kozak C., O'Hara C.D., Leder P. Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Gen. Dev. 12:1998;3382-3393.
    • (1998) Gen. Dev. , vol.12 , pp. 3382-3393
    • Chester, N.1    Kuo, F.2    Kozak, C.3    O'Hara, C.D.4    Leder, P.5
  • 20
    • 0032499967 scopus 로고    scopus 로고
    • Cdna cloning of mouse blm gene, the homologue to human Bloom's syndrome gene, which is highly expressed in the testis at the mrna level
    • Seki T., Wang W., Okumura N., Seki M., Katada T., Enomoto T. Cdna cloning of mouse blm gene, the homologue to human Bloom's syndrome gene, which is highly expressed in the testis at the mrna level. Biochim. Biophys. Acta. 1398:1998;377-381.
    • (1998) Biochim. Biophys. Acta , vol.1398 , pp. 377-381
    • Seki, T.1    Wang, W.2    Okumura, N.3    Seki, M.4    Katada, T.5    Enomoto, T.6
  • 21
    • 0032964641 scopus 로고    scopus 로고
    • The DNA helicase activity of blm is necessary for the correction of the genomic instability of Bloom syndrome cells
    • Neff N.F., Ellis N.A., Ye T.Z., Noonan J., Huang K., Sanz M., Proytcheva M. The DNA helicase activity of blm is necessary for the correction of the genomic instability of Bloom syndrome cells. Mol. Biol. Cell. 10:1999;665-676.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 665-676
    • Neff, N.F.1    Ellis, N.A.2    Ye, T.Z.3    Noonan, J.4    Huang, K.5    Sanz, M.6    Proytcheva, M.7
  • 24
    • 0036719389 scopus 로고    scopus 로고
    • Gene targeting in hemostasis. Factor x
    • Rosen E.D. Gene targeting in hemostasis. Factor x. Frontiers Biosci. 7:2000;1915-1925.
    • (2000) Frontiers Biosci. , vol.7 , pp. 1915-1925
    • Rosen, E.D.1
  • 25
    • 0029854371 scopus 로고    scopus 로고
    • Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor v
    • Cui J., O'Shea K.S., Purkayastha A., Saunders T.L., Ginsburg D. Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor v. Nature. 384:1996;66-68.
    • (1996) Nature , vol.384 , pp. 66-68
    • Cui, J.1    O'Shea, K.S.2    Purkayastha, A.3    Saunders, T.L.4    Ginsburg, D.5
  • 27
    • 0028134716 scopus 로고
    • Chromosomal breakage in human spermatozoa, a heterozygous effect of the Bloom syndrome mutation
    • Martin R.H., Rademaker A., German J. Chromosomal breakage in human spermatozoa, a heterozygous effect of the Bloom syndrome mutation. Am. J. Hum. Genet. 55:1994;1242-1246.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 1242-1246
    • Martin, R.H.1    Rademaker, A.2    German, J.3
  • 28
    • 0018417955 scopus 로고
    • No increased chromosome breakage in three Bloom's syndrome heterozygotes
    • E.M. Kuhn, E. Therman, No increased chromosome breakage in three Bloom's syndrome heterozygotes, J. Med. Genet. 16 (1979) 219-222.
    • (1979) J. Med. Genet. , vol.16 , pp. 219-222
    • Kuhn, E.M.1    Therman, E.2
  • 29
    • 0022411109 scopus 로고
    • Presence of abnormally high incidences of sister chromatid exchanges in three successive cell cycles in Bloom's syndrome lymphocytes
    • Tsuji H., Kojima T. Presence of abnormally high incidences of sister chromatid exchanges in three successive cell cycles in Bloom's syndrome lymphocytes. Chromosoma. 93:1985;87-93.
    • (1985) Chromosoma , vol.93 , pp. 87-93
    • Tsuji, H.1    Kojima, T.2
  • 30
    • 0022364961 scopus 로고
    • Evidence for chromosome instability in vivo in Bloom syndrome: Increased numbers of micronuclei in exfoliated cells
    • Rosin M.P., German J. Evidence for chromosome instability in vivo in Bloom syndrome: increased numbers of micronuclei in exfoliated cells. Hum. Genet. 71:1985;187-191.
    • (1985) Hum. Genet. , vol.71 , pp. 187-191
    • Rosin, M.P.1    German, J.2
  • 31
    • 0017061852 scopus 로고
    • Cytological demonstration of mitotic crossing-over in man
    • Therman E., Kuhn E.M. Cytological demonstration of mitotic crossing-over in man. Cytogenet. Cell Genet. 17:1976;254-267.
    • (1976) Cytogenet. Cell Genet. , vol.17 , pp. 254-267
    • Therman, E.1    Kuhn, E.M.2
  • 32
    • 0018651621 scopus 로고
    • Quantitative replicon analysis of DNA synthesis in cancer-prone conditions and the defects in Bloom's syndrome
    • Ockey C.H. Quantitative replicon analysis of DNA synthesis in cancer-prone conditions and the defects in Bloom's syndrome. J. Cell Sci. 40:1979;125-144.
    • (1979) J. Cell Sci. , vol.40 , pp. 125-144
    • Ockey, C.H.1
  • 33
    • 0022644068 scopus 로고
    • Delayed DNA maturation, a possible cause of the elevated sister-chromatid exchange in Bloom's syndrome
    • Ockey C.H., Saffhill R. Delayed DNA maturation, a possible cause of the elevated sister-chromatid exchange in Bloom's syndrome. Carcinogenesis. 7:1986;53-57.
    • (1986) Carcinogenesis , vol.7 , pp. 53-57
    • Ockey, C.H.1    Saffhill, R.2
  • 34
    • 0025302748 scopus 로고
    • An abnormal profile of DNA replication intermediates in Bloom's syndrome
    • Lonn U., Lonn S., Nylen U., Winblad G., German J. An abnormal profile of DNA replication intermediates in Bloom's syndrome. Cancer Res. 50:1990;3141-3145.
    • (1990) Cancer Res. , vol.50 , pp. 3141-3145
    • Lonn, U.1    Lonn, S.2    Nylen, U.3    Winblad, G.4    German, J.5
  • 37
    • 0033952627 scopus 로고    scopus 로고
    • Large central acellular zones indicating myoepithelial tumor differentiation in high-grade invasive ductal carcinomas as markers of predisposition to lung and brain metastases
    • Tsuda H., Takarabe T., Hasegawa F., Fukutomi T., Hirohashi S. Large central acellular zones indicating myoepithelial tumor differentiation in high-grade invasive ductal carcinomas as markers of predisposition to lung and brain metastases. Am. J. Surg. Pathol. 24:2000;197-202.
    • (2000) Am. J. Surg. Pathol. , vol.24 , pp. 197-202
    • Tsuda, H.1    Takarabe, T.2    Hasegawa, F.3    Fukutomi, T.4    Hirohashi, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.