Multi-organ damage in human dipeptidyl peptidase 4 transgenic mice infected with Middle East respiratory syndrome-coronavirus

PLoS ONE

Volumn 10, Issue 12, 2015, Pages

  Zhao, Guangyu ^a   Jiang, Yuting ^a   Qiu, Hongjie ^a   Gao, Tongtong ^a   Zeng, Yang ^a   Guo, Yan ^a   Yu, Hong ^a   Li, Junfeng ^a   Kou, Zhihua ^a   Du, Lanying ^b   Tan, Wenjie ^d   Jiang, Shibo ^b,c   Sun, Shihui ^a   Zhou, Yusen ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b NEW YORK BLOOD CENTER   (United States)

^c FUDAN UNIVERSITY   (China)

^d BEIJING HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; DIPEPTIDYL PEPTIDASE IV; VIRUS RNA; DPP4 PROTEIN, MOUSE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE SEVERITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KIDNEY; KIDNEY INJURY; LIVER INJURY; LUNG; MACROPHAGE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOUSE; MOUSE MODEL; NERVE CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN INJURY; PARALYSIS; PROTEIN EXPRESSION; SPLEEN INJURY; TRANSGENIC MOUSE; VIRAL TROPISM; VIRUS LOAD; VIRUS PNEUMONIA; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; COMPLICATION; CORONAVIRUS INFECTION; ENZYME IMMUNOASSAY; FEMALE; GENETICS; HUMAN; METABOLISM; MULTIPLE ORGAN FAILURE; PATHOGENICITY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY;

ANIMALS; CHEMOKINES; CORONAVIRUS INFECTIONS; CYTOKINES; DIPEPTIDYL PEPTIDASE 4; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MULTIPLE ORGAN FAILURE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84957573378     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0145561     Document Type: Article

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