Total Synthesis of K777: Successful Application of Transition-Metal-Catalyzed Alkyne Hydrothiolation toward the Modular Synthesis of a Potent Cysteine Protease Inhibitor

Organic Letters

Volumn 18, Issue 3, 2016, Pages 492-495

  Kiemele, Erica R ^a   Wathier, Matthew ^a   Bichler, Paul ^a   Love, Jennifer A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2-AMINO-4-PHENYLBUTYRIC ACID; ALKYNE; AMINE; AMINO ACID; AMINOBUTYRIC ACID DERIVATIVE; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; N-PIP-PHENYLALANINE-HOMOPHENYLALANINE-VINYL SULFONE PHENYL; SULFIDE; THIOL DERIVATIVE; TRANSITION ELEMENT; VINYL DERIVATIVE;

CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ALKYNES; AMINES; AMINO ACIDS; AMINOBUTYRATES; CATALYSIS; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; MOLECULAR STRUCTURE; STEREOISOMERISM; SULFHYDRYL COMPOUNDS; SULFIDES; TRANSITION ELEMENTS; VINYL COMPOUNDS;

EID: 84957564516     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/acs.orglett.5b03535     Document Type: Article

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