Elative rates of Michael reactions of 2′-(phenethyl)thiol with vinyl sulfones, vinyl sulfonate esters, and vinyl sulfonamides relevant to vinyl sulfonyl cysteine protease inhibitors

Organic Letters

Volumn 5, Issue 11, 2003, Pages 1967-1970

  Reddick, Jason J ^a   Cheng, Jianming ^a   Roush, William R ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' (PHENETHYL)THIOL; CYSTEINE PROTEINASE INHIBITOR; ESTER; SULFONE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; DIVINYL SULFONE; SULFONAMIDE;

ARTICLE; DRUG SYNTHESIS; KINETICS; MICHAEL ADDITION; REACTION TIME; SUBSTITUTION REACTION; CATALYSIS; SYNTHESIS;

CATALYSIS; CYSTEINE PROTEINASE INHIBITORS; KINETICS; SULFONAMIDES; SULFONES;

EID: 0042352240     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol034555l     Document Type: Article

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