Antithrombotic peptides from scolopendra subspinipes mutilans hydrolysates

International Journal of Peptide Research and Therapeutics

Volumn 20, Issue 2, 2014, Pages 245-252

  Kong, Yi ^a   Li, Shuai ^a   Shao, Yu ^a   He, Zhi Long ^a   Chen, Mei Mei ^a   Ming, Xin ^b   Wei, Ji Fu ^c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNC Hamner Institute for Drug Safety Sciences   (United States)

^c THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Antithrombotic peptides; Enzymatic hydrolysates; Platelet aggregation inhibitor; Scolopendra subspinipes mutilans

Indexed keywords

ASPARTYLLEUCYLASPARTYLHISTIDYLTYROSYLSERYLPHENYLALANINE PEPTIDE; ISOLEUCYLARGINYLASPARTYLLEUCINE PEPTIDE; PEPTIDE; PHENYLALANYLSERYLALANYLPROLYLALANYLVALYLTYROSINE PEPTIDE; PROTEIN HYDROLYSATE; SEPHADEX; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BLOOD CLOTTING TIME; CONTROLLED STUDY; DEGRADATION KINETICS; ELECTROSPRAY MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTEIN PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCOLOPENDRA; SCOLOPENDRA SUBSPINIPES MUTILANS; STRUCTURE ANALYSIS; THROMBOCYTE AGGREGATION; ULTRAFILTRATION;

EID: 84957435222     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-013-9387-3     Document Type: Article

References (22)

1. An S, Ma D, Wei J, Yang X, Yang H, Yang H, Xu X, He S, Lai R (2011) A novel allergen Tab y 1 with inhibitory activity of platelet aggregation from salivary glands of horseflies. Allergy 66(11):1420-1427
2. Carrasco-Castilla J, Hernández-Álvarez AJ, Jiménez-Martínez C, Jacinto-Hernández C, Alaiz M, Girón-Calle J, Vioque J, Dávila-Ortiz G (2012) Antioxidant and metal chelating activities of peptide fractions from phaseolin and bean protein hydrolysates. Food Chem 135:1789-1795
3. Fitzgerald DJ, Roy L, Catella F, FitzGerald GA (1986) Platelet activation in unstable coronary disease. N Engl J Med 315(16):983-989
4. Gibbs BF, Zougman A, Masse R, Mulligan C (2004) Production and characterization of bioactive peptides from soy hydrolysate and soy-fermented food. Food Res Int 37(2):123-131
5. Han J, You D, Xu X, Han W, Lu Y, Lai R, Meng Q (2008) An anticoagulant serine protease from the wasp venom of Vespa magnifica. Toxicon 51(5):914-922
6. Kogushi M, Matsuoka T, Kawata T, Kuramochi H, Kawaguchi S, Murakami K, Hiyoshi H, Suzuki S, Kawahara T, Kajiwara A (2011) The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs. Eur J Pharmacol 657(1):131-137
7. Kong Y, Huang S-L, Shao Y, Li S, Wei J-F (2013) Purification and characterization of a novel antithrombotic peptide from Scolopendra subspinipes mutilans. J Ethnopharmacol 145:182-186
8. Lee K, Kim S-H (2005) SSGE and DEE, new peptides isolated from a soy protein hydrolysate that inhibit platelet aggregation. Food Chem 90(3):389-393
9. Li X, Han G, Zhang S, Lu L, Yang J-x, Zhao W-j (2004) Effects of Veratrum nigrum var. ussuri ense alkaloids on platelet aggregation and time of coagulation and bleeding. Chin Tradit Herb Drugs 11:1269-1272
10. Ma D, Xu X, An S, Liu H, Yang X, Andersen JF, Wang Y, Tokumasu F, Ribeiro JM, Francischetti IM (2011) A novel family of RGD-containing disintegrin (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets integrins αIIbβ3 and αVβ3 and inhibits platelet aggregation and angiogenesis. Thromb Haemost 105(6):1032
11. Megías C, Pedroche J, Yust MM, Girón-Calle J, Alaiz M, Millán F, Vioque J (2007) Affinity purification of copper-chelating peptides from sunflower protein hydrolysates. J Agric Food Chem 55(16):6509-6514
12. Meisel H, FitzGerald R (2003) Biofunctional peptides from milk proteins: mineral binding and cytomodulatory effects. Curr Pharm Des 9(16):1289-1296
13. Murray B, FitzGerald R (2007) Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr Pharm Des 13(8):773-791
14. Negrea S, Minelli A (1995) Chilopoda. Encycl Bioespeologica 1:249-254
15. Pemberton RW (1999) Insects and other arthropods used as drugs in Korean traditional medicine. J Ethnopharmacol 65(3):207-216
16. Wei J-F, Li T, Wei X-L, Sun Q-Y, Yang F-M, Chen Q-Y, Wang W-Y, Xiong Y-L, He S-H (2006a) Purification, characterization and cytokine release function of a novel Arg-49 phospholipase A 2 from the venom of Protobothrops mucrosquamatus. Biochimie 88(10):1331-1342
17. Wei J-F, Wei X-l, Chen Q-Y, Huang T, Qiao L-Y, Wang W-Y, Xiong Y-L, He S-H (2006b) N49 phospholipase A 2, a unique subgroup of snake venom group II phospholipase A2. Biochimica et Biophys Acta (BBA) Gen Subj 1760(3):462-471
18. Wu Y, Li J, Wang J, Si Q, Zhang J, Jiang Y, Chu L (2009) Anti-atherogenic effects of centipede acidic protein in rats fed an atherogenic diet. J Ethnopharmacol 122(3):509-516
19. Wu H, Liu Z, Dong S, Zhao Y, Huang H, Zeng M (2012) Formation of ferric oxyhydroxide nanoparticles mediated by peptides in anchovy (Engraulis japonicus) muscle protein hydrolysate. J Agric Food Chem 61(1):219-224
20. Yang H, Xu X, Ma D, Zhang K, Lai R (2008) A phospholipase A1 platelet activator from the wasp venom of Vespa magnifica (Smith). Toxicon 51(2):289-296
21. You W-K, Sohn Y-D, Kim K-Y, Park D-H, Jang Y, Chung K-H (2004) Purification and molecular cloning of a novel serine protease from the centipede, Scolopendra subspinipes mutilans. Insect Biochem Mol Biol 34(3):239-250
22. Zhao Y, Li B, Dong S, Liu Z, Zhao X, Wang J, Zeng M (2009) A novel ACE inhibitory peptide isolated from Acaudina molpadioidea hydrolysate. Peptides 30(6):1028-1033