Anti-atherogenic effects of centipede acidic protein in rats fed an atherogenic diet

Journal of Ethnopharmacology

Volumn 122, Issue 3, 2009, Pages 509-516

  Wu, Yanling ^a   Li, Junyun ^a   Wang, Jusu ^a   Si, Qiuju ^a   Zhang, Jianping ^a   Jiang, Ye ^a   Chu, Li ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerosis; Centipede acidic protein; Dyslipidemia; Hemorrheology

Indexed keywords

ACID PROTEIN; CENTIPEDE ACIDIC PROTEIN; CHOLESTEROL; COLECALCIFEROL; ENDOTHELIN 1; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; NATURAL PRODUCT; NITRIC OXIDE; SIMVASTATIN; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTICLE; ATHEROGENIC DIET; ATHEROSCLEROSIS; BLOOD RHEOLOGY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MEGADOSE; EXPERIMENTAL MODEL; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; LIVER; LOW DRUG DOSE; MALE; NONHUMAN; RAT; THORACIC AORTA; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL;

ACIDS; ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTILIPEMIC AGENTS; AORTA; ARTHROPODS; ATHEROSCLEROSIS; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; HEMORHEOLOGY; LIPID PEROXIDATION; LIPIDS; MALE; MALONDIALDEHYDE; MEDICINE, CHINESE TRADITIONAL; NITRIC OXIDE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN; SUPEROXIDE DISMUTASE;

CHILOPODA; RATTUS;

EID: 63649086493     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.01.017     Document Type: Article

References (34)

1. Ashakumary L., and Vijayammal P.L. Effect of nicotine on antioxidant defence mechanisms in rats fed a high-fat diet. Pharmacology 52 (1996) 153-158
2. Chailley B., Giraud F., and Claret M. Alteration in human erythrocyte shape and the state of spectrin and phospholipid phosphorilation induced by cholesterol depletion. Biochimica et Biophysica Acta 643 (1981) 636-641
3. Chow C.K. Vitamin E and oxidative stress. Free Radical Biology & Medicine 11 (1991) 215-232
4. Cohen E., and Quistad G.B. Cytotoxic effects of arthropod venoms on various cultured cells. Toxicon 36 (1998) 353-358
5. Deepa P.R., and Varalakshmi P. Salubrious effect of low molecular weight heparin on atherogenic diet-induced cardiac, hepatic and renal lipid peroxidation and collapse of antioxidant defences. Molecular and Cellular Biochemistry 254 (2003) 111-116
6. Deepa P.R., and Varalakshmi P. Favourable modulation of the inflammatory changes in hypercholesterolemic atherogenesis by a low-molecular-weight heparin derivative. International Journal of Cardiology 106 (2006) 338-347
7. Deliconstantinos G., Villiotou V., and Stavrides J.C. Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes. Biochemical Pharmacology 49 (1995) 1589-1600
8. Ercan M., and Konukoglu D. Role of plasma viscosity and plasma homocysteine level on hyperinsulinemic obese female subjects. Clinical Hemorheology and Microcirculation 38 (2008) 227-234
9. Fonseca V.A., Fink L.M., and Kern P.A. Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects. Atherosclerosis 167 (2003) 105-109
10. Frick M.H., Elo O., Haapa K., Heinonen O.P., Heinsalmi P., Helo P., Huttunen J.K., Kaitaniemi P., Koskinen P., and Manninen V. Helsinki heart study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. The New England Journal of Medicine 317 (1987) 1237-1245
11. Goldstein J.L., Schrott H.G., Hazzard W.R., Bierman E.L., and Motulsky A.G. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. The Journal of Clinical Investigation 52 (1973) 1544-1568
12. Jeppesen J., Hein H.O., Suadicani P., and Gyntelberg F. Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen male study. Circulation 97 (1998) 1029-1036
13. Koenig W., Sund M., Filipiak B., Döring A., Löwel H., and Ernst E. Plasma viscosity and the risk of coronary heart disease: results from the MONICA-Augsburg Cohort Study, 1984 to 1992. Arteriosclerosis, Thrombosis, and Vascular Biology 18 (1998) 768-772
14. Kourembanas S., McQuillan L.P., Leung G.K., and Faller D.V. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. The Journal of Clinical Investigation 92 (1993) 99-104
15. Kuo C.F., Jao Y.C., and Yang P. Downregulation of hepatic lipoprotein assembly in rats by fermented products of Monascus pilosus. Nutrition 24 (2008) 477-483
16. Libby P. Inflammation in atherosclerosis. Nature 420 (2002) 868-874
17. Lowe G.D., Lee A.J., Rumley A., Price J.F., and Fowkes F.G. Blood viscosity and risk of cardiovascular events: the Edinburgh artery study. British Journal of Haematology 96 (1997) 168-173
18. Mohamed A.H., Zaid E., El-Beih N.M., and Abd E.-Aal.A. Effects of an extract from centipede Scolopendra morsitans on intestine, uterus and heart contractions and on blood glucose and liver and muscle glycogen levels. Toxicon 18 (1980) 581-589
19. Navab M., Hama S.Y., Hough G.P., Hedrick C.C., Sorenson R., La D.B.N., Kobashigawa J.A., Fonarow G.C., Berliner J.A., Laks H., and Fogelman A.M. High density associated enzymes: their role in vascular biology. Current Opinion in Lipidology 9 (1998) 449-456
20. Pemberton R.W. Insects and other arthropods used as drugs in Korean traditional medicine. Journal of Ethnopharmacology 65 (1999) 207-216
21. Prasad K., and Kalra J. Oxygen free radicals and hypercholesterolemic atherosclerosis: effect of vitamin E. American Heart Journal 125 (1993) 958-973
22. Ren Y., Houghton P., and Hider R.C. Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. The Journal of Pharmacy and Pharmacology 58 (2006) 989-996
23. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362 (1993) 801-809
24. Ross R. Atherosclerosis-an inflammatory disease. The New England Journal of Medicine 340 (1999) 115-126
25. Schwartz R.S., Holmes Jr. D.R., and Topol E.J. The restenosis paradigm revisited: an alternative proposal for cellular mechanisms. Journal of the American College of Cardiology 20 (1992) 1284-1293
26. Soufi M., Sattler A.M., Herzum M., Maisch B., and Schaefer J.R. Molecular basis of obesity and the risk for cardiovascular disease. Herz 31 (2006) 200-206
27. Stankiewicz M., Hamon A., Benkhalifa R., Kadziela W., Hue B., Lucas S., Mebs D., and Pelhate M. Effects of a centipede venom fraction on insect nervous system, a native Xenopus oocyte receptor and on an expressed Drosophila muscarinic receptor. Toxicon 37 (1999) 1431-1445
28. Strauss B.H., Chisholm R.J., Keeley F.W., Gotlieb A.I., Logan R.A., and Armstrong P.W. Extracellular matrix remodeling after balloon angioplasty injury in a rabbit model of restenosis. Circulation Research 75 (1994) 650-658
29. Sundell J. Obesity and diabetes as risk factors for coronary artery disease: from the epidemiological aspect to the initial vascular mechanisms. Diabetes, Obesity & Metabolism 7 (2005) 9-20
30. Thompson G.R., and Barter P.J. Clinical lipidology at the end of the millennium. Current Opinion in Lipidology 10 (1999) 521-526
31. Vayá A., Martínez M., Guillén M., Dalmau J., and Aznar J. Erythrocyte deformability in young familial hypercholesterolemics. Clinical Hemorheology and Microcirculation 19 (1998) 43-48
32. Xylander W.E., and Nevermann L. Antibacterial activity in the hemolymph of myriapods (Arthropoda). Journal of Invertebrate Pathology 56 (1990) 206-214
33. Yang P.Y., Rui Y.C., Lu L., Li T.J., Liu S.Q., Yan H.X., and Wang H.Y. Time courses of vascular endothelial growth factor and intercellular adhesion molecule-1 expressions in aortas of atherosclerotic rats. Life Sciences 77 (2005) 2529-2539
34. Yilmaz M., Biri A., Bukan N., Karakoç A., Sancak B., Törüner F., and Paşaoǧlu H. Levels of lipoprotein and homocysteine in non-obese and obese patients with polycystic ovary syndrome. Gynecological Endocrinology 20 (2005) 258-263