Purification, characterization and cytokine release function of a novel Arg-49 phospholipase A2 from the venom of Protobothrops mucrosquamatus

Biochimie

Volumn 88, Issue 10, 2006, Pages 1331-1342

  Wei, Ji Fu ^a,c   Li, Tao ^a   Wei, Xiao Long ^a   Sun, Qian Yun ^b   Yang, Fu Mei ^b   Chen, Qiu Yu ^a   Wang, Wan Yu ^d   Xiong, Yu Liang ^d   He, Shao Heng ^a,c  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d KUNMING INSTITUTE OF ZOOLOGY   (China)

Author keywords

Monocytes; Myotoxicity; Phospholipase A2; Protobothrops mucrosquamatus; T cells

Indexed keywords

AMINO ACID; ARGININE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; PHOSPHOLIPASE A2; PROMUTOXIN; SNAKE VENOM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; PHOSPHOLIPASE A;

AMINO ACID SEQUENCE; ANIMAL MODEL; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; CYTOKINE RELEASE; EDEMA; ENZYME ACTIVITY; GASTROCNEMIUS MUSCLE; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; MONOCYTE; MOUSE; MUSCLE NECROSIS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTOBOTHROPS MUCROSQUAMATUS; SNAKE; T LYMPHOCYTE; ANIMAL; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RAT; WISTAR RAT;

ANIMALIA; PROTOBOTHROPS MUCROSQUAMATUS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ARGININE; BASE SEQUENCE; CROTALID VENOMS; CYTOKINES; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MONOCYTES; PHOSPHOLIPASES A; RATS; RATS, WISTAR; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; T-LYMPHOCYTES;

EID: 33750529560     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2006.05.003     Document Type: Article

References (58)

1. 2. J. Biol. Chem. 269 (1994) 13057-13060
2. 2 enzymes: classification and characterization. Biochim. Biophys. Acta 1488 (2000) 1-19
3. 2 according to sequence. Evolutionary and pharmacological implications. Eur. J. Biochem. 137 (1983) 545-551
4. 2 with lysine in place of aspartate 49. Functional consequences for calcium and substrate binding. J. Biol. Chem. 259 (1984) 13839-13843
5. 2. J. Biol. Chem. 261 (1986) 4797-4804
6. 2, ecarpholin S, from the venom of Echis carinatus sochureki (saw-scaled viper). Biochem. J. 319 (1996) 961-968
7. 2 homologue from Vipera ammodytes venom. Eur. J. Biochem. 202 (1991) 1165-1168
8. Tsai I.H., Wang Y.M., Chen Y.H., Tsai T.S., and Tu M.C. Venom phospholipases A2 of bamboo viper (Trimeresurus stejnegeri): molecular characterization, geographic variations and evidence of multiple ancestries. Biochem. J. 377 (2004) 215-223
9. 2. Biochim. Biophys. Acta 1760 (2006) 462-471
10. 2 from the venom of Agkistrodon blomhoffii ussurensis. Int. J. Biochem. Cell Biol. 37 (2005) 558-565
11. 2 from the venom of Trimeresurus jerdonii snake. Toxicon 40 (2002) 1313-1319
12. 2. J. Nat. Toxins 11 (2002) 25-33
13. Fuly A.L., Soares A.M., Marcussi S., Giglio J.R., and Guimaraes J.A. Signal transduction pathways involved in the platelet aggregation induced by a D49 phospholipase A2 isolated from Bothrops jararacussu snake venom. Biochimie 86 (2004) 731-739
14. 2 enzymes from snake venoms. Toxicon 45 (2005) 1147-1161
15. 2 isoforms from Bothrops jararacussu snake venom. Biochimie 85 (2003) 983-991
16. 2 from the venom of Taiwan habu (Trimeresurus mucrosquamatus). Biochem. J. 311 (1995) 895-900
17. 2 homologue from Bothrops moojeni (Caissaca) snake venom. Arch. Biochem. Biophys. 373 (2000) 7-15
18. 2 homologue from Bothrops neuwiedi pauloensis venom. Arch. Biochem. Biophys. 378 (2000) 201-209
19. 2 from Bothrops atrox snake venom. Biochem. Pharmacol. 64 (2002) 1179-1186
20. 2 purified from porcine pancreas and snake venoms. Toxicon 31 (1993) 949-956
21. 2 homologue piratoxin-i in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide. Biochem. Pharmacol. 59 (2000) 1289-1294
22. Teixeira C.F., Landucci E.C., Antunes E., Chacur M., and Cury Y. Inflammatory effects of snake venom myotoxic phospholipases A2. Toxicon 42 (2003) 947-962
23. 2 isolated from Bothrops asper snake venom: role of catalytic activity. Toxicon 45 (2005) 335-346
24. 2 homologues: dissociation between enzymatic and biological activities. Eur. J. Pharmacol. 343 (1998) 257-263
25. 4. Nature 227 (1970) 680-685
26. Brandford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
27. 2 from venom of Trimeresurus flavoviridis (Habu snake). J. Biochem. (Tokyo) 88 (1980) 443-451
28. 2 activity by a colorimetric assay using a pH indicator. Toxicon 25 (1987) 1181-1188
29. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The CLUSTAL-X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25 (1997) 4876-4882
30. 2 from Bothrops asper snake venom: synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region. Eur. J. Biochem. 253 (1998) 452-461
31. 2 homologue from the venom of the snake Bothrops atrox. Toxicon 44 (2004) 91-101
32. Born G.V.R., and Cross M.J. The aggregation of blood platelets. J. Physiol. 186 (1963) 178-195
33. Rodrigues V.M., Soares A.M., Andriao-Escarso S.H., Franceschi A.M., Rucavado A., Gutierrez J.M., and Giglio J.R. Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom. Biochimie 83 (2001) 471-479
34. 2: a stable dimer interface and a native monomeric intermediate. Arch. Biochem. Biophys. 411 (2003) 112-120
35. 2+-independent membrane damaging activity. Biochemistry 40 (2001) 6912-6920
36. 2. Biochimie 87 (2005) 993-1003
37. 2 of Calloselasma rhodostoma and Trimeresurus mucrosquamatus. Arch. Biochem. Biophys. 387 (2001) 257-264
38. 2 of two primitive tree vipers Trimeresurus puniceus and Trimeresurus borneensis. FEBS J. 272 (2005) 3015-3025
39. Chen Y.H., Wang Y.M., Hseu M.J., and Tsai I.H. Molecular evolution and structure-function relationships of crotoxin-like and asparagine-6-containing phospholipases A2 in pit viper venoms. Biochem. J. 381 (2004) 25-34
40. 2 myotoxin from Agkistrodon contortrix laticinctus snake venom. Arch. Biochem. Biophys. 326 (1996) 21-30
41. 2 from Agkistrodon piscivorus piscivorus venom. Eur. J. Biochem. 176 (1988) 353-357
42. 2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49. Biochemistry 33 (1994) 14714-14722
43. 2 in the venom of Bungarus fasciatus (banded krait). J. Biochem. (Tokyo) 112 (1992) 707-713
44. 2 from Agkistrodon piscivorus piscivorus snake venom: synthetic C-terminal peptides from Lys49, but not from Asp49 myotoxins, exert membrane-damaging activities. Toxicon 39 (2001) 1587-1594
45. 2 homologue. Int. J. Biochem. Cell Biol. 34 (2002) 1268-1278
46. 2 enzymes. Toxicon 42 (2003) 827-840
47. 2 from snake venoms. Toxicon 42 (2003) 307-312
48. 2 homologue. Int. J. Biochem. Cell Biol. 32 (2000) 63-71
49. 2 from Bothrops neuwiedi pauloensis snake venom. Toxicon 44 (2004) 305-314
50. Gallagher P., Bao Y., Serrano S.M., Laing G.D., Theakston R.D., Gutierrez J.M., Escalante T., Zigrino P., Moura-da-Silva A.M., Nischt R., Mauch C., Moskaluk C., and Fox J.W. Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin. Arch. Biochem. Biophys. 441 (2005) 1-15
51. Wei J.F., Mo Y.Z., Qiao L.Y., Wei X.L., Chen H.Q., Xie H., Fu Y.L., Wang W.Y., Xiong Y.L., and He S.H. Potent histamine-releasing activity of atrahagin, a novel snake venom metalloproteinase. Int. J. Biochem. Cell Biol. 38 (2006) 510-520
52. Havt A., Toyama M.H., do Nascimento N.R., Toyama D.O., Nobre A.C., Martins A.M., Barbosa P.S., Novello J.C., Boschero A.C., Carneiro E.M., Fonteles M.C., and Monteiro H.S. A new C-type animal lectin isolated from Bothrops pirajai is responsible for the snake venom major effects in the isolated kidney. Int. J. Biochem. Cell Biol. 37 (2005) 130-141
53. 2 into the rat pleural cavity. Toxicon 38 (2000) 1773-1785
54. 2 in inflammatory and allergic diseases: not just enzymes. J. Allergy Clin. Immunol. 116 (2005) 1000-1006
55. Lomonte B., Tarkowski A., and Hanson L.A. Host response to Bothrops asper snake venom. Analysis of edema formation, inflammatory cells, and cytokine release in a mouse model. Inflammation (1993) 93-105
56. Rucavado A., Escalante T., Teixeira C.F., Fernandes C.M., Diaz C., and Gutierrez J.M. Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper. Mediators Inflamm. 11 (2002) 121-128
57. Zuliani J.P., Gutierrez J.M., Casais e Silva L.L., Coccuzzo Sampaio S., Lomonte B., and Teixeira C.F. Activation of cellular functions in macrophages by venom secretory Asp-49 and Lys-49 phospholipases A2. Toxicon 46 5 (2005) 523-532
58. 2 induce cytokine release from blood and synovial fluid monocytes. Eur. J. Immunol. 32 (2002) 67-76