-
1
-
-
0001104604
-
On the healing of aseptic bone cavities by implantation of antiseptic decalcified bone
-
Senn N. On the healing of aseptic bone cavities by implantation of antiseptic decalcified bone. Am. J. Med. Sci. 1889, 98:219-240.
-
(1889)
Am. J. Med. Sci.
, vol.98
, pp. 219-240
-
-
Senn, N.1
-
2
-
-
0347150317
-
On the formation of new bone in bone transplantation
-
Levander G. On the formation of new bone in bone transplantation. Acta Chir. Scand. 1934, 74:425-426.
-
(1934)
Acta Chir. Scand.
, vol.74
, pp. 425-426
-
-
Levander, G.1
-
3
-
-
0001121713
-
A study of bone regeneration
-
Levander G. A study of bone regeneration. Surg. Gynecol. Obstet. 1938, 67:705-714.
-
(1938)
Surg. Gynecol. Obstet.
, vol.67
, pp. 705-714
-
-
Levander, G.1
-
4
-
-
33749183609
-
Tissue induction
-
Levander G. Tissue induction. Nature 1945, 155:148-149.
-
(1945)
Nature
, vol.155
, pp. 148-149
-
-
Levander, G.1
-
5
-
-
84969383438
-
Recent investigation on the growth of bone
-
Lacroix P. Recent investigation on the growth of bone. Nature 1945, 156.
-
(1945)
Nature
, pp. 156
-
-
Lacroix, P.1
-
6
-
-
0015155737
-
Bone morphogenetic protein
-
Urist M.R., Strates B.S. Bone morphogenetic protein. J. Dent. Res. 1971, 50:1392-1406.
-
(1971)
J. Dent. Res.
, vol.50
, pp. 1392-1406
-
-
Urist, M.R.1
Strates, B.S.2
-
7
-
-
34250019537
-
Bone: formation by autoinduction
-
Urist M.R. Bone: formation by autoinduction. Science 1965, 150:893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
8
-
-
0015358386
-
Biochemical sequences in the transformation of normal fibroblasts in adolescent rats
-
Reddi A.H., Huggins C. Biochemical sequences in the transformation of normal fibroblasts in adolescent rats. Proc. Natl. Acad. Sci. U. S. A. 1972, 69:1601-1605.
-
(1972)
Proc. Natl. Acad. Sci. U. S. A.
, vol.69
, pp. 1601-1605
-
-
Reddi, A.H.1
Huggins, C.2
-
9
-
-
0036899744
-
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients
-
Govender S., Csimma C., Genant H.K., Valentin-Opran A., Amit Y., Arbel R., Aro H., Atar D., Bishay M., Borner M.G., Chiron P., Choong P., Cinats J., Courtenay B., Feibel R., Geulette B., Gravel C., Haas N., Raschke M., Hammacher E., van der Velde D., Hardy P., Holt M., Josten C., Ketterl R.L., Lindeque B., Lob G., Mathevon H., McCoy G., Marsh D., Miller R., Munting E., Oevre S., Nordsletten L., Patel A., Pohl A., Rennie W., Reynders P., Rommens P.M., Rondia J., Rossouw W.C., Daneel P.J., Ruff S., Ruter A., Santavirta S., Schildhauer T.A., Gekle C., Schnettler R., Segal D., Seiler H., Snowdowne R.B., Stapert J., Taglang G., Verdonk R., Vogels L., Weckbach A., Wentzensen A., Wisniewski T., Group BMPEiSfTTS Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J. Bone Joint Surg. Am. 2002, 84-A:2123-2134.
-
(2002)
J. Bone Joint Surg. Am.
, pp. 2123-2134
-
-
Govender, S.1
Csimma, C.2
Genant, H.K.3
Valentin-Opran, A.4
Amit, Y.5
Arbel, R.6
Aro, H.7
Atar, D.8
Bishay, M.9
Borner, M.G.10
Chiron, P.11
Choong, P.12
Cinats, J.13
Courtenay, B.14
Feibel, R.15
Geulette, B.16
Gravel, C.17
Haas, N.18
Raschke, M.19
Hammacher, E.20
van der Velde, D.21
Hardy, P.22
Holt, M.23
Josten, C.24
Ketterl, R.L.25
Lindeque, B.26
Lob, G.27
Mathevon, H.28
McCoy, G.29
Marsh, D.30
Miller, R.31
Munting, E.32
Oevre, S.33
Nordsletten, L.34
Patel, A.35
Pohl, A.36
Rennie, W.37
Reynders, P.38
Rommens, P.M.39
Rondia, J.40
Rossouw, W.C.41
Daneel, P.J.42
Ruff, S.43
Ruter, A.44
Santavirta, S.45
Schildhauer, T.A.46
Gekle, C.47
Schnettler, R.48
Segal, D.49
Seiler, H.50
Snowdowne, R.B.51
Stapert, J.52
Taglang, G.53
Verdonk, R.54
Vogels, L.55
Weckbach, A.56
Wentzensen, A.57
Wisniewski, T.58
more..
-
10
-
-
33745713060
-
Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial
-
Jones A.L., Bucholz R.W., Bosse M.J., Mirza S.K., Lyon T.R., Webb L.X., Pollak A.N., Golden J.D., Valentin-Opran A., Group BMPEiSfTT-AS Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J. Bone Joint Surg. Am. 2006, 88:1431-1441.
-
(2006)
J. Bone Joint Surg. Am.
, vol.88
, pp. 1431-1441
-
-
Jones, A.L.1
Bucholz, R.W.2
Bosse, M.J.3
Mirza, S.K.4
Lyon, T.R.5
Webb, L.X.6
Pollak, A.N.7
Golden, J.D.8
Valentin-Opran, A.9
-
11
-
-
0033163468
-
Clinical evaluation of rhBMP-2/ACS in orthopedic trauma: a progress report
-
Riedel G.E., Valentin-Opran A. Clinical evaluation of rhBMP-2/ACS in orthopedic trauma: a progress report. Orthopedics 1999, 22:663-665.
-
(1999)
Orthopedics
, vol.22
, pp. 663-665
-
-
Riedel, G.E.1
Valentin-Opran, A.2
-
12
-
-
33744815209
-
Recombinant human bone morphogenetic protein-2 in open tibial fractures: a subgroup analysis of data combined from two prospective randomized studies
-
Swiontkowski M.F., Aro H.T., Donell S., Esterhai J.L., Goulet J., Jones A., Kregor P.J., Nordsletten L., Paiement G., Patel A. Recombinant human bone morphogenetic protein-2 in open tibial fractures: a subgroup analysis of data combined from two prospective randomized studies. J. Bone Joint Surg. Am. 2006, 88:1258-1265.
-
(2006)
J. Bone Joint Surg. Am.
, vol.88
, pp. 1258-1265
-
-
Swiontkowski, M.F.1
Aro, H.T.2
Donell, S.3
Esterhai, J.L.4
Goulet, J.5
Jones, A.6
Kregor, P.J.7
Nordsletten, L.8
Paiement, G.9
Patel, A.10
-
13
-
-
84868642757
-
Recombinant human BMP-2 for the treatment of open tibial fractures
-
Wei S., Cai X., Huang J., Xu F., Liu X., Wang Q. Recombinant human BMP-2 for the treatment of open tibial fractures. Orthopedics 2012, 35:e847-e854.
-
(2012)
Orthopedics
, vol.35
, pp. e847-e854
-
-
Wei, S.1
Cai, X.2
Huang, J.3
Xu, F.4
Liu, X.5
Wang, Q.6
-
14
-
-
79959950769
-
A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned
-
Carragee E.J., Hurwitz E.L., Weiner B.K. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J. 2011, 11:471-491.
-
(2011)
Spine J.
, vol.11
, pp. 471-491
-
-
Carragee, E.J.1
Hurwitz, E.L.2
Weiner, B.K.3
-
15
-
-
79959950769
-
A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned
-
Carragee E.J., Hurwitz E.L., Weiner B.K. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J. 2011, 11(6):471-491.
-
(2011)
Spine J.
, vol.11
, Issue.6
, pp. 471-491
-
-
Carragee, E.J.1
Hurwitz, E.L.2
Weiner, B.K.3
-
16
-
-
44949237161
-
Bone morphogenetic protein (BMP) for fracture healing in adults
-
Garrison K.R., Shemilt I., Donell S., Ryder J.J., Mugford M., Harvey I., Song F., Alt V. Bone morphogenetic protein (BMP) for fracture healing in adults. Cochrane Database Syst. Rev. 2010, CD006950.
-
(2010)
Cochrane Database Syst. Rev.
, pp. CD006950
-
-
Garrison, K.R.1
Shemilt, I.2
Donell, S.3
Ryder, J.J.4
Mugford, M.5
Harvey, I.6
Song, F.7
Alt, V.8
-
17
-
-
84883298054
-
Cancer after spinal fusion: the role of bone morphogenetic protein
-
Lad S.P., Bagley J.H., Karikari I.O., Babu R., Ugiliweneza B., Kong M., Isaacs R.E., Bagley C.A., Gottfried O.N., Patil C.G., Boakye M. Cancer after spinal fusion: the role of bone morphogenetic protein. Neurosurgery 2013, 73:440-449.
-
(2013)
Neurosurgery
, vol.73
, pp. 440-449
-
-
Lad, S.P.1
Bagley, J.H.2
Karikari, I.O.3
Babu, R.4
Ugiliweneza, B.5
Kong, M.6
Isaacs, R.E.7
Bagley, C.A.8
Gottfried, O.N.9
Patil, C.G.10
Boakye, M.11
-
18
-
-
84865218588
-
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites
-
Gao H., Chakraborty G., Lee-Lim A.P., Mo Q., Decker M., Vonica A., Shen R., Brogi E., Brivanlou A.H., Giancotti F.G. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell 2012, 150:764-779.
-
(2012)
Cell
, vol.150
, pp. 764-779
-
-
Gao, H.1
Chakraborty, G.2
Lee-Lim, A.P.3
Mo, Q.4
Decker, M.5
Vonica, A.6
Shen, R.7
Brogi, E.8
Brivanlou, A.H.9
Giancotti, F.G.10
-
19
-
-
84857407558
-
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators
-
Owens P., Pickup M.W., Novitskiy S.V., Chytil A., Gorska A.E., Aakre M.E., West J., Moses H.L. Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:2814-2819.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 2814-2819
-
-
Owens, P.1
Pickup, M.W.2
Novitskiy, S.V.3
Chytil, A.4
Gorska, A.E.5
Aakre, M.E.6
West, J.7
Moses, H.L.8
-
21
-
-
79959962169
-
Retrograde ejaculation after anterior lumbar interbody fusion using rhBMP-2: a cohort controlled study
-
Carragee E.J., Mitsunaga K.A., Hurwitz E.L., Scuderi G.J. Retrograde ejaculation after anterior lumbar interbody fusion using rhBMP-2: a cohort controlled study. Spine J. 2011, 11:511-516.
-
(2011)
Spine J.
, vol.11
, pp. 511-516
-
-
Carragee, E.J.1
Mitsunaga, K.A.2
Hurwitz, E.L.3
Scuderi, G.J.4
-
22
-
-
79959579500
-
Recombinant human bone morphogenetic protein-2: a randomized trial in open tibial fractures treated with reamed nail fixation
-
Aro H.T., Govender S., Patel A.D., Hernigou P., Perera, de G., regorio A., Popescu G.I., Golden J.D., Christensen J., Valentin A. Recombinant human bone morphogenetic protein-2: a randomized trial in open tibial fractures treated with reamed nail fixation. J. Bone Joint Surg. Am. 2011, 93:801-808.
-
(2011)
J. Bone Joint Surg. Am.
, vol.93
, pp. 801-808
-
-
Aro, H.T.1
Govender, S.2
Patel, A.D.3
Hernigou, P.4
Perera de, G.5
regorio, A.6
Popescu, G.I.7
Golden, J.D.8
Christensen, J.9
Valentin, A.10
-
23
-
-
57149094500
-
Heterotopic ossification after the use of commercially available recombinant human bone morphogenetic proteins in four patients
-
Axelrad T.W., Steen B., Lowenberg D.W., Creevy W.R., Einhorn T.A. Heterotopic ossification after the use of commercially available recombinant human bone morphogenetic proteins in four patients. J. Bone Joint Surg. Br. 2008, 90:1617-1622.
-
(2008)
J. Bone Joint Surg. Br.
, vol.90
, pp. 1617-1622
-
-
Axelrad, T.W.1
Steen, B.2
Lowenberg, D.W.3
Creevy, W.R.4
Einhorn, T.A.5
-
24
-
-
0004249279
-
Purification of bovine bone morphogenetic protein by hydroxyapatite chromatography
-
Urist M.R., Huo Y.K., Brownell A.G., Hohl W.M., Buyske J., Lietze A., Tempst P., Hunkapiller M., DeLange R.J. Purification of bovine bone morphogenetic protein by hydroxyapatite chromatography. Proc. Natl. Acad. Sci. U. S. A. 1984, 81:371-375.
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 371-375
-
-
Urist, M.R.1
Huo, Y.K.2
Brownell, A.G.3
Hohl, W.M.4
Buyske, J.5
Lietze, A.6
Tempst, P.7
Hunkapiller, M.8
DeLange, R.J.9
-
25
-
-
47549102735
-
Optimal delivery systems for bone morphogenetic proteins in orthopedic applications should model initial tissue repair structures by using a heparin-incorporated fibrin-fibronectin matrix
-
Han D., Liu W., Ao Q., Wang G. Optimal delivery systems for bone morphogenetic proteins in orthopedic applications should model initial tissue repair structures by using a heparin-incorporated fibrin-fibronectin matrix. Med. Hypotheses 2008, 71:374-378.
-
(2008)
Med. Hypotheses
, vol.71
, pp. 374-378
-
-
Han, D.1
Liu, W.2
Ao, Q.3
Wang, G.4
-
26
-
-
73949119177
-
Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A: current challenges in BMP delivery
-
Haidar Z.S., Hamdy R.C., Tabrizian M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A: current challenges in BMP delivery. Biotechnol. Lett. 2009, 31:1817-1824.
-
(2009)
Biotechnol. Lett.
, vol.31
, pp. 1817-1824
-
-
Haidar, Z.S.1
Hamdy, R.C.2
Tabrizian, M.3
-
27
-
-
0024256133
-
Novel regulators of bone formation: molecular clones and activities
-
Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., Hewick R.M., Wang E.A. Novel regulators of bone formation: molecular clones and activities. Science 1988, 242:1528-1534.
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
28
-
-
0031061210
-
A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation
-
Boyne P.J., Marx R.E., Nevins M., Triplett G., Lazaro E., Lilly L.C., Alder M., Nummikoski P. A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation. Int. J. Periodontics Restor. Dent. 1997, 17:11-25.
-
(1997)
Int. J. Periodontics Restor. Dent.
, vol.17
, pp. 11-25
-
-
Boyne, P.J.1
Marx, R.E.2
Nevins, M.3
Triplett, G.4
Lazaro, E.5
Lilly, L.C.6
Alder, M.7
Nummikoski, P.8
-
29
-
-
84918776767
-
Bone substitutes in orthopaedic surgery: from basic science to clinical practice
-
Campana V., Milano G., Pagano E., Barba M., Cicione C., Salonna G., Lattanzi W., Logroscino G. Bone substitutes in orthopaedic surgery: from basic science to clinical practice. J. Mater. Sci. Mater. Med. 2014, 25:2445-2461.
-
(2014)
J. Mater. Sci. Mater. Med.
, vol.25
, pp. 2445-2461
-
-
Campana, V.1
Milano, G.2
Pagano, E.3
Barba, M.4
Cicione, C.5
Salonna, G.6
Lattanzi, W.7
Logroscino, G.8
-
30
-
-
0037082557
-
Delivery of recombinant human bone morphogenetic protein-2 using a compression-resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primate
-
(Phila, Pa 1976)
-
Suh D.Y., Boden S.D., Louis-Ugbo J., Mayr M., Murakami H., Kim H.S., Minamide A., Hutton W.C. Delivery of recombinant human bone morphogenetic protein-2 using a compression-resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primate. Spine 2002, 27:353-360. (Phila, Pa 1976).
-
(2002)
Spine
, vol.27
, pp. 353-360
-
-
Suh, D.Y.1
Boden, S.D.2
Louis-Ugbo, J.3
Mayr, M.4
Murakami, H.5
Kim, H.S.6
Minamide, A.7
Hutton, W.C.8
-
31
-
-
79960692785
-
Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics
-
Wulsten D., Glatt V., Ellinghaus A., Schmidt-Bleek K., Petersen A., Schell H., Lienau J., Sebald W., Ploger F., Seemann P., Duda G.N. Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics. Eur. Cell Mater. 2011, 21:177-192.
-
(2011)
Eur. Cell Mater.
, vol.21
, pp. 177-192
-
-
Wulsten, D.1
Glatt, V.2
Ellinghaus, A.3
Schmidt-Bleek, K.4
Petersen, A.5
Schell, H.6
Lienau, J.7
Sebald, W.8
Ploger, F.9
Seemann, P.10
Duda, G.N.11
-
32
-
-
78751572964
-
A 5 mm femoral defect in female but not in male rats leads to a reproducible atrophic non-union
-
Mehta M., Schell H., Schwarz C., Peters A., Schmidt-Bleek K., Ellinghaus A., Bail H.J., Duda G.N., Lienau J. A 5 mm femoral defect in female but not in male rats leads to a reproducible atrophic non-union. Arch. Orthop. Trauma. Surg. 2011, 131:121-129.
-
(2011)
Arch. Orthop. Trauma. Surg.
, vol.131
, pp. 121-129
-
-
Mehta, M.1
Schell, H.2
Schwarz, C.3
Peters, A.4
Schmidt-Bleek, K.5
Ellinghaus, A.6
Bail, H.J.7
Duda, G.N.8
Lienau, J.9
-
33
-
-
79956095821
-
Effects of protein dose and delivery system on BMP-mediated bone regeneration
-
Boerckel J.D., Kolambkar Y.M., Dupont K.M., Uhrig B.A., Phelps E.A., Stevens H.Y., Garcia A.J., Guldberg R.E. Effects of protein dose and delivery system on BMP-mediated bone regeneration. Biomaterials 2011, 32:5241-5251.
-
(2011)
Biomaterials
, vol.32
, pp. 5241-5251
-
-
Boerckel, J.D.1
Kolambkar, Y.M.2
Dupont, K.M.3
Uhrig, B.A.4
Phelps, E.A.5
Stevens, H.Y.6
Garcia, A.J.7
Guldberg, R.E.8
-
34
-
-
0035222452
-
Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions
-
Friedlaender G.E., Perry C.R., Cole J.D., Cook S.D., Cierny G., Muschler G.F., Zych G.A., Calhoun J.H., LaForte A.J., Yin S. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J. Bone Joint Surg. Am. 2001, 83-A(Suppl. 1):S151-S158.
-
(2001)
J. Bone Joint Surg. Am.
, pp. S151-S158
-
-
Friedlaender, G.E.1
Perry, C.R.2
Cole, J.D.3
Cook, S.D.4
Cierny, G.5
Muschler, G.F.6
Zych, G.A.7
Calhoun, J.H.8
LaForte, A.J.9
Yin, S.10
-
35
-
-
84871386329
-
Effect of a novel nonviral gene delivery of BMP-2 on bone healing
-
560142.
-
Schwabe P., Greiner S., Ganzert R., Eberhart J., Dahn K., Stemberger A., Plank C., Schmidmaier G., Wildemann B. Effect of a novel nonviral gene delivery of BMP-2 on bone healing. Sci.World J. 2012, 2012. 560142.
-
(2012)
Sci.World J.
, vol.2012
-
-
Schwabe, P.1
Greiner, S.2
Ganzert, R.3
Eberhart, J.4
Dahn, K.5
Stemberger, A.6
Plank, C.7
Schmidmaier, G.8
Wildemann, B.9
-
36
-
-
80855130884
-
Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants
-
Strobel C., Bormann N., Kadow-Romacker A., Schmidmaier G., Wildemann B. Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants. J. Control Release 2011, 156:37-45.
-
(2011)
J. Control Release
, vol.156
, pp. 37-45
-
-
Strobel, C.1
Bormann, N.2
Kadow-Romacker, A.3
Schmidmaier, G.4
Wildemann, B.5
-
37
-
-
77956016728
-
Bone morphogenetic proteins in critical-size bone defects: what are the options?
-
Schmidmaier G., Capanna R., Wildemann B., Beque T., Lowenberg D. Bone morphogenetic proteins in critical-size bone defects: what are the options?. Injury 2009, 40(Suppl. 3):S39-S43.
-
(2009)
Injury
, vol.40
, pp. S39-S43
-
-
Schmidmaier, G.1
Capanna, R.2
Wildemann, B.3
Beque, T.4
Lowenberg, D.5
-
38
-
-
79751536672
-
Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing
-
Wang Q., Huang C., Xue M., Zhang X. Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing. Bone 2011, 48:524-532.
-
(2011)
Bone
, vol.48
, pp. 524-532
-
-
Wang, Q.1
Huang, C.2
Xue, M.3
Zhang, X.4
-
39
-
-
73649136476
-
Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN
-
Seemann P., Brehm A., Konig J., Reissner C., Stricker S., Kuss P., Haupt J., Renninger S., Nickel J., Sebald W., Groppe J.C., Ploger F., Pohl J., Schmidt-von Kegler M., Walther M., Gassner I., Rusu C., Janecke A.R., Dathe K., Mundlos S. Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN. PLoS Genet. 2009, 5:e1000747.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000747
-
-
Seemann, P.1
Brehm, A.2
Konig, J.3
Reissner, C.4
Stricker, S.5
Kuss, P.6
Haupt, J.7
Renninger, S.8
Nickel, J.9
Sebald, W.10
Groppe, J.C.11
Ploger, F.12
Pohl, J.13
Schmidt-von Kegler, M.14
Walther, M.15
Gassner, I.16
Rusu, C.17
Janecke, A.R.18
Dathe, K.19
Mundlos, S.20
more..
-
40
-
-
79955374782
-
Bone morphogenetic protein (BMP) 1-3 enhances bone repair
-
Grgurevic L., Macek B., Mercep M., Jelic M., Smoljanovic T., Erjavec I., Dumic-Cule I., Prgomet S., Durdevic D., Vnuk D., Lipar M., Stejskal M., Kufner V., Brkljacic J., Maticic D., Vukicevic S. Bone morphogenetic protein (BMP) 1-3 enhances bone repair. Biochem. Biophys. Res. Commun. 2011, 408:25-31.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 25-31
-
-
Grgurevic, L.1
Macek, B.2
Mercep, M.3
Jelic, M.4
Smoljanovic, T.5
Erjavec, I.6
Dumic-Cule, I.7
Prgomet, S.8
Durdevic, D.9
Vnuk, D.10
Lipar, M.11
Stejskal, M.12
Kufner, V.13
Brkljacic, J.14
Maticic, D.15
Vukicevic, S.16
-
41
-
-
0037733130
-
Skeletal overexpression of noggin results in osteopenia and reduced bone formation
-
Devlin R.D., Du Z., Pereira R.C., Kimble R.B., Economides A.N., Jorgetti V., Canalis E. Skeletal overexpression of noggin results in osteopenia and reduced bone formation. Endocrinology 2003, 144:1972-1978.
-
(2003)
Endocrinology
, vol.144
, pp. 1972-1978
-
-
Devlin, R.D.1
Du, Z.2
Pereira, R.C.3
Kimble, R.B.4
Economides, A.N.5
Jorgetti, V.6
Canalis, E.7
-
42
-
-
70649094222
-
BMP2 signaling in bone development and repair
-
Rosen V. BMP2 signaling in bone development and repair. Cytokine Growth Factor Rev. 2009, 20:475-480.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 475-480
-
-
Rosen, V.1
-
43
-
-
84969406589
-
Pre-clinical fracture repair investigations: meeting report from the 32nd annual meeting of the american society for bone and mineral research
-
McDonald M.M. Pre-clinical fracture repair investigations: meeting report from the 32nd annual meeting of the american society for bone and mineral research. BoneKEy 2011, 8(March):165-170.
-
(2011)
BoneKEy
, vol.8
, Issue.MARCH
, pp. 165-170
-
-
McDonald, M.M.1
-
44
-
-
85038498776
-
Expression of BMP2 in skeletal progenitor cells is required for bone fracture repair
-
Intini G., Cox K., Rosen V. Expression of BMP2 in skeletal progenitor cells is required for bone fracture repair. J. Bone Miner. Res. 2010, 25(S1):S1-S81.
-
(2010)
J. Bone Miner. Res.
, vol.25
, pp. S1-S81
-
-
Intini, G.1
Cox, K.2
Rosen, V.3
-
45
-
-
0037376627
-
Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation
-
Gerstenfeld L.C., Cullinane D.M., Barnes G.L., Graves D.T., Einhorn T.A. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J. Cell Biochem. 2003, 88:873-884.
-
(2003)
J. Cell Biochem.
, vol.88
, pp. 873-884
-
-
Gerstenfeld, L.C.1
Cullinane, D.M.2
Barnes, G.L.3
Graves, D.T.4
Einhorn, T.A.5
-
46
-
-
2542505844
-
Scar-free healing: from embryonic mechanisms to adult therapeutic intervention
-
Ferguson M.W., O'Kane S. Scar-free healing: from embryonic mechanisms to adult therapeutic intervention. Philos. Trans. R. Soc. London B. Biol. Sci. 2004, 359:839-850.
-
(2004)
Philos. Trans. R. Soc. London B. Biol. Sci.
, vol.359
, pp. 839-850
-
-
Ferguson, M.W.1
O'Kane, S.2
-
47
-
-
84943660786
-
BMPs and the muscle-bone connection
-
Sartori R., Sandri M. BMPs and the muscle-bone connection. Bone 2015.
-
(2015)
Bone
-
-
Sartori, R.1
Sandri, M.2
-
48
-
-
84933544655
-
Embryo development. BMP gradients: a paradigm for morphogen-mediated developmental patterning
-
aaa5838.
-
Bier E., De Robertis E.M. Embryo development. BMP gradients: a paradigm for morphogen-mediated developmental patterning. Science 2015, 348:aaa5838.
-
(2015)
Science
, vol.348
-
-
Bier, E.1
De Robertis, E.M.2
-
49
-
-
84969372790
-
Development of physiologically based pharmacokinetic model (PBPK) of BMP2 in mice
-
Utturkar A., Paul B., Akkiraju H., Bonor J., Dhurjati P., Nohe A. Development of physiologically based pharmacokinetic model (PBPK) of BMP2 in mice. Biol. Syst. Open Access 2013, 2.
-
(2013)
Biol. Syst. Open Access
, vol.2
-
-
Utturkar, A.1
Paul, B.2
Akkiraju, H.3
Bonor, J.4
Dhurjati, P.5
Nohe, A.6
-
50
-
-
33846004405
-
Bone morphogenetic proteins and their antagonists
-
Gazzerro E., Canalis E. Bone morphogenetic proteins and their antagonists. Rev. Endocr. Metab. Disord. 2006, 7:51-65.
-
(2006)
Rev. Endocr. Metab. Disord.
, vol.7
, pp. 51-65
-
-
Gazzerro, E.1
Canalis, E.2
-
51
-
-
0037069653
-
Structural basis of BMP signalling inhibition by the cystine knot protein noggin
-
Groppe J., Greenwald J., Wiater E., Rodriguez-Leon J., Economides A.N., Kwiatkowski W., Affolter M., Vale W.W., Izpisua Belmonte J.C., Choe S. Structural basis of BMP signalling inhibition by the cystine knot protein noggin. Nature 2002, 420:636-642.
-
(2002)
Nature
, vol.420
, pp. 636-642
-
-
Groppe, J.1
Greenwald, J.2
Wiater, E.3
Rodriguez-Leon, J.4
Economides, A.N.5
Kwiatkowski, W.6
Affolter, M.7
Vale, W.W.8
Izpisua Belmonte, J.C.9
Choe, S.10
-
53
-
-
33947305450
-
Molecular aspects of fracture healing: which are the important molecules?
-
Tsiridis E., Upadhyay N., Giannoudis P. Molecular aspects of fracture healing: which are the important molecules?. Injury 2007, 38(Suppl. 1):S11-25.
-
(2007)
Injury
, vol.38
, pp. S11-25
-
-
Tsiridis, E.1
Upadhyay, N.2
Giannoudis, P.3
-
54
-
-
84922721002
-
Improved bone defect healing by a superagonistic GDF5 variant derived from a patient with multiple synostoses syndrome
-
Degenkolbe E., Schwarz C., Ott C.E., Konig J., Schmidt-Bleek K., Ellinghaus A., Schmidt T., Lienau J., Ploger F., Mundlos S., Duda G.N., Willie B.M., Seemann P. Improved bone defect healing by a superagonistic GDF5 variant derived from a patient with multiple synostoses syndrome. Bone 2015, 73:111-119.
-
(2015)
Bone
, vol.73
, pp. 111-119
-
-
Degenkolbe, E.1
Schwarz, C.2
Ott, C.E.3
Konig, J.4
Schmidt-Bleek, K.5
Ellinghaus, A.6
Schmidt, T.7
Lienau, J.8
Ploger, F.9
Mundlos, S.10
Duda, G.N.11
Willie, B.M.12
Seemann, P.13
-
55
-
-
77951243657
-
Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity
-
Song K., Krause C., Shi S., Patterson M., Suto R., Grgurevic L., Vukicevic S., van Dinther M., Falb D., Ten Dijke P., Alaoui-Ismaili M.H. Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity. J. Biol. Chem. 2010, 285:12169-12180.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12169-12180
-
-
Song, K.1
Krause, C.2
Shi, S.3
Patterson, M.4
Suto, R.5
Grgurevic, L.6
Vukicevic, S.7
van Dinther, M.8
Falb, D.9
Ten Dijke, P.10
Alaoui-Ismaili, M.H.11
-
56
-
-
84957430547
-
-
Berlin C-U, Germany
-
Seemann P., Mundlos S., Reissner C., Duda G.N., Zimmer J. Bone Morphogenetic Protein 2 (bmp2) Variants with Reduced BMP Antagonist Sensitivity 2010, Berlin C-U, Germany.
-
(2010)
Bone Morphogenetic Protein 2 (bmp2) Variants with Reduced BMP Antagonist Sensitivity
-
-
Seemann, P.1
Mundlos, S.2
Reissner, C.3
Duda, G.N.4
Zimmer, J.5
-
57
-
-
84898890256
-
The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing
-
Vukicevic S., Oppermann H., Verbanac D., Jankolija M., Popek I., Curak J., Brkljacic J., Pauk M., Erjavec I., Francetic I., Dumic-Cule I., Jelic M., Durdevic D., Vlahovic T., Novak R., Kufner V., Bordukalo Niksic T., Kozlovic M., Banic Tomisic Z., Bubic-Spoljar J., Bastalic I., Vikic-Topic S., Peric M., Pecina M., Grgurevic L. The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing. Int. Orthop. 2014, 38:635-647.
-
(2014)
Int. Orthop.
, vol.38
, pp. 635-647
-
-
Vukicevic, S.1
Oppermann, H.2
Verbanac, D.3
Jankolija, M.4
Popek, I.5
Curak, J.6
Brkljacic, J.7
Pauk, M.8
Erjavec, I.9
Francetic, I.10
Dumic-Cule, I.11
Jelic, M.12
Durdevic, D.13
Vlahovic, T.14
Novak, R.15
Kufner, V.16
Bordukalo Niksic, T.17
Kozlovic, M.18
Banic Tomisic, Z.19
Bubic-Spoljar, J.20
Bastalic, I.21
Vikic-Topic, S.22
Peric, M.23
Pecina, M.24
Grgurevic, L.25
more..
-
58
-
-
84884903343
-
Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells
-
Wang Y., Hong S., Li M., Zhang J., Bi Y., He Y., Liu X., Nan G., Su Y., Zhu G., Li R., Zhang W., Wang J., Zhang H., Kong Y., Shui W., Wu N., He Y., Chen X., Luu H.H., Haydon R.C., Shi L.L., He T.C., Qin J. Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J. Orthop. Res. 2013, 31:1796-1803.
-
(2013)
J. Orthop. Res.
, vol.31
, pp. 1796-1803
-
-
Wang, Y.1
Hong, S.2
Li, M.3
Zhang, J.4
Bi, Y.5
He, Y.6
Liu, X.7
Nan, G.8
Su, Y.9
Zhu, G.10
Li, R.11
Zhang, W.12
Wang, J.13
Zhang, H.14
Kong, Y.15
Shui, W.16
Wu, N.17
He, Y.18
Chen, X.19
Luu, H.H.20
Haydon, R.C.21
Shi, L.L.22
He, T.C.23
Qin, J.24
more..
-
59
-
-
84863833253
-
L51P-A BMP2 variant with osteoinductive activity via inhibition of noggin
-
Albers C.E., Hofstetter W., Sebald H.J., Sebald W., Siebenrock K.A., Klenke F.M. L51P-A BMP2 variant with osteoinductive activity via inhibition of noggin. Bone 2012, 51:401-406.
-
(2012)
Bone
, vol.51
, pp. 401-406
-
-
Albers, C.E.1
Hofstetter, W.2
Sebald, H.J.3
Sebald, W.4
Siebenrock, K.A.5
Klenke, F.M.6
-
61
-
-
0034267930
-
Temporal and spatial expression of bone morphogenetic protein-2, -4, and -7 during distraction osteogenesis in rabbits
-
Rauch F., Lauzier D., Croteau S., Travers R., Glorieux F.H., Hamdy R. Temporal and spatial expression of bone morphogenetic protein-2, -4, and -7 during distraction osteogenesis in rabbits. Bone 2000, 27:453-459.
-
(2000)
Bone
, vol.27
, pp. 453-459
-
-
Rauch, F.1
Lauzier, D.2
Croteau, S.3
Travers, R.4
Glorieux, F.H.5
Hamdy, R.6
-
62
-
-
34548232182
-
Mechanical loading and delta12prostaglandin J2 induce bone morphogenetic protein-2, peroxisome proliferator-activated receptor gamma-1, and bone nodule formation in an osteoblastic cell line
-
Siddhivarn C., Banes A., Champagne C., Riche E.L., Weerapradist W., Offenbacher S. Mechanical loading and delta12prostaglandin J2 induce bone morphogenetic protein-2, peroxisome proliferator-activated receptor gamma-1, and bone nodule formation in an osteoblastic cell line. J. Periodontal. Res. 2007, 42:383-392.
-
(2007)
J. Periodontal. Res.
, vol.42
, pp. 383-392
-
-
Siddhivarn, C.1
Banes, A.2
Champagne, C.3
Riche, E.L.4
Weerapradist, W.5
Offenbacher, S.6
-
63
-
-
33845918633
-
Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression
-
Sumanasinghe R.D., Bernacki S.H., Loboa E.G. Osteogenic differentiation of human mesenchymal stem cells in collagen matrices: effect of uniaxial cyclic tensile strain on bone morphogenetic protein (BMP-2) mRNA expression. Tissue Eng. 2006, 12:3459-3465.
-
(2006)
Tissue Eng.
, vol.12
, pp. 3459-3465
-
-
Sumanasinghe, R.D.1
Bernacki, S.H.2
Loboa, E.G.3
-
64
-
-
79251549490
-
Mechanical loading increased BMP-2 expression which promoted osteogenic differentiation of tendon-derived stem cells
-
Rui Y.F., Lui P.P., Ni M., Chan L.S., Lee Y.W., Chan K.M. Mechanical loading increased BMP-2 expression which promoted osteogenic differentiation of tendon-derived stem cells. J. Orthop. Res. 2011, 29:390-396.
-
(2011)
J. Orthop. Res.
, vol.29
, pp. 390-396
-
-
Rui, Y.F.1
Lui, P.P.2
Ni, M.3
Chan, L.S.4
Lee, Y.W.5
Chan, K.M.6
-
65
-
-
0035215805
-
Weight-bearing alters the expression of collagen types I and II, BMP 2/4 and osteocalcin in the early stages of distraction osteogenesis
-
Radomisli T.E., Moore D.C., Barrach H.J., Keeping H.S., Ehrlich M.G. Weight-bearing alters the expression of collagen types I and II, BMP 2/4 and osteocalcin in the early stages of distraction osteogenesis. J. Orthop. Res. 2001, 19:1049-1056.
-
(2001)
J. Orthop. Res.
, vol.19
, pp. 1049-1056
-
-
Radomisli, T.E.1
Moore, D.C.2
Barrach, H.J.3
Keeping, H.S.4
Ehrlich, M.G.5
-
66
-
-
0032970328
-
Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis
-
Sato M., Ochi T., Nakase T., Hirota S., Kitamura Y., Nomura S., Yasui N. Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis. J. Bone Miner. Res. 1999, 14:1084-1095.
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1084-1095
-
-
Sato, M.1
Ochi, T.2
Nakase, T.3
Hirota, S.4
Kitamura, Y.5
Nomura, S.6
Yasui, N.7
-
67
-
-
0031876132
-
Expression of bone matrix proteins mRNA during distraction osteogenesis
-
Sato M., Yasui N., Nakase T., Kawahata H., Sugimoto M., Hirota S., Kitamura Y., Nomura S., Ochi T. Expression of bone matrix proteins mRNA during distraction osteogenesis. J Bone Miner. Res. 1998, 13:1221-1231.
-
(1998)
J Bone Miner. Res.
, vol.13
, pp. 1221-1231
-
-
Sato, M.1
Yasui, N.2
Nakase, T.3
Kawahata, H.4
Sugimoto, M.5
Hirota, S.6
Kitamura, Y.7
Nomura, S.8
Ochi, T.9
-
68
-
-
0033674978
-
Reduced expression of BMP-3 due to mechanical loading: a link between mechanical stimuli and tissue differentiation
-
Aspenberg P., Basic N., Tagil M., Vukicevic S. Reduced expression of BMP-3 due to mechanical loading: a link between mechanical stimuli and tissue differentiation. Acta Orthop. Scand. 2000, 71:558-562.
-
(2000)
Acta Orthop. Scand.
, vol.71
, pp. 558-562
-
-
Aspenberg, P.1
Basic, N.2
Tagil, M.3
Vukicevic, S.4
-
69
-
-
70449527365
-
Are endogenous BMPs necessary for bone healing during distraction osteogenesis?
-
Alam N., St-Arnaud R., Lauzier D., Rosen V., Hamdy R.C. Are endogenous BMPs necessary for bone healing during distraction osteogenesis?. Clin. Orthop. Relat. Res. 2009, 467:3190-3198.
-
(2009)
Clin. Orthop. Relat. Res.
, vol.467
, pp. 3190-3198
-
-
Alam, N.1
St-Arnaud, R.2
Lauzier, D.3
Rosen, V.4
Hamdy, R.C.5
-
70
-
-
0037215488
-
Expression of bone morphogenetic proteins during mandibular distraction osteogenesis
-
discussion 209-10
-
Campisi P., Hamdy R.C., Lauzier D., Amako M., Rauch F., Lessard M.L. Expression of bone morphogenetic proteins during mandibular distraction osteogenesis. Plast Reconstr. Surg. 2003, 111:201-208. discussion 209-10.
-
(2003)
Plast Reconstr. Surg.
, vol.111
, pp. 201-208
-
-
Campisi, P.1
Hamdy, R.C.2
Lauzier, D.3
Amako, M.4
Rauch, F.5
Lessard, M.L.6
-
71
-
-
80053087080
-
Mechanical regulation of vascular growth and tissue regeneration in vivo
-
Boerckel J.D., Uhrig B.A., Willett N.J., Huebsch N., Guldberg R.E. Mechanical regulation of vascular growth and tissue regeneration in vivo. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:E674-E680.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. E674-E680
-
-
Boerckel, J.D.1
Uhrig, B.A.2
Willett, N.J.3
Huebsch, N.4
Guldberg, R.E.5
-
72
-
-
70349762953
-
In vivo model for evaluating the effects of mechanical stimulation on tissue-engineered bone repair
-
Boerckel J.D., Dupont K.M., Kolambkar Y.M., Lin A.S., Guldberg R.E. In vivo model for evaluating the effects of mechanical stimulation on tissue-engineered bone repair. J. Biomech. Eng. 2009, 131:084502.
-
(2009)
J. Biomech. Eng.
, vol.131
, pp. 084502
-
-
Boerckel, J.D.1
Dupont, K.M.2
Kolambkar, Y.M.3
Lin, A.S.4
Guldberg, R.E.5
-
73
-
-
84969406582
-
Effects of in vivo mechanical loading on large bone defect regeneration
-
Boerckel J.D., Kolambkar Y.M., Stevens H.Y., Lin A.S., Dupont K.M., Guldberg R.E. Effects of in vivo mechanical loading on large bone defect regeneration. J. Orthop. Res. 2011.
-
(2011)
J. Orthop. Res.
-
-
Boerckel, J.D.1
Kolambkar, Y.M.2
Stevens, H.Y.3
Lin, A.S.4
Dupont, K.M.5
Guldberg, R.E.6
-
75
-
-
36348967117
-
A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft)
-
McKay W.F., Peckham S.M., Badura J.M. A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft). Int. Orthop. 2007, 31:729-734.
-
(2007)
Int. Orthop.
, vol.31
, pp. 729-734
-
-
McKay, W.F.1
Peckham, S.M.2
Badura, J.M.3
-
76
-
-
84871338144
-
Mechanical load modulates the stimulatory effect of BMP2 in a rat nonunion model
-
Schwarz C., Wulsten D., Ellinghaus A., Lienau J., Willie B.M., Duda G.N. Mechanical load modulates the stimulatory effect of BMP2 in a rat nonunion model. Tissue Eng. A 2013, 19:247-254.
-
(2013)
Tissue Eng. A
, vol.19
, pp. 247-254
-
-
Schwarz, C.1
Wulsten, D.2
Ellinghaus, A.3
Lienau, J.4
Willie, B.M.5
Duda, G.N.6
-
77
-
-
84861510353
-
BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway
-
Kopf J., Petersen A., Duda G.N., Knaus P. BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway. BMC Biol. 2012, 10:37.
-
(2012)
BMC Biol.
, vol.10
, pp. 37
-
-
Kopf, J.1
Petersen, A.2
Duda, G.N.3
Knaus, P.4
|