α-Synuclein amyloid fibrils with two entwined, asymmetrically associated protofibrils

Journal of Biological Chemistry

Volumn 291, Issue 5, 2016, Pages 2310-2318

  Dearborn, Altaira D ^a   Wall, Joseph S ^b   Cheng, Naiqian ^a   Heymann, J Bernard ^a   Kajava, Andrey V ^c,d   Varkey, Jobin ^e,f   Langen, Ralf ^e   Steven, Alasdair C ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c Centre National de la Recherche Scientifique   (France)

^d ITMO UNIVERSITY   (Russian Federation)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^f KARUNYA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON MICROSCOPES; ELECTRON MICROSCOPY; GLYCOPROTEINS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; METAL IONS; METALS; NEURODEGENERATIVE DISEASES; TRANSMISSION ELECTRON MICROSCOPY;

AMYLOID FIBRIL; CRYO-ELECTRON MICROSCOPY; METAL BINDING SITES; NEURODEGENERATIVE; PARKINSON DISEASE; POLYMORPHIC VARIANT; PROTOFIBRILS; SCANNING TRANSMISSION ELECTRON MICROSCOPY;

SCANNING ELECTRON MICROSCOPY;

ALPHA SYNUCLEIN; AMYLOID; ION;

ARTICLE; BINDING SITE; CRYOELECTRON MICROSCOPY; IMAGE PROCESSING; METAL BINDING; MOLECULAR IMAGING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTOFIBRIL; SCANNING TRANSMISSION ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMISTRY; HUMAN; LEWY BODY; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; AMYLOID; BINDING SITES; CRYOELECTRON MICROSCOPY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IONS; LEWY BODIES; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84957004495     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.698787     Document Type: Article

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