Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes

Molecular Cell

Volumn 48, Issue 5, 2012, Pages 799-810

  Singer, Stephan ^a,e   Zhao, Ruiying ^a   Barsotti, Anthony M ^a   Ouwehand, Anette ^c   Fazollahi, Mina ^a,b   Coutavas, Elias ^d   Breuhahn, Kai ^e   Neumann, Olaf ^e   Longerich, Thomas ^e   Pusterla, Tobias ^f   Powers, Maureen A ^g   Giles, Keith M ^h   Leedman, Peter J ^h   Hess, Jochen ^e,f   Grunwald, David ^c   Bussemaker, Harmen J ^a   Singer, Robert H ⁱ   Schirmacher, Peter ^e   Prives, Carol ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Delft University of Technology ^*  (United States)

^c DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^d ROCKEFELLER UNIVERSITY   (United States)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^f GERMAN CANCER RESEARCH CENTER   (Germany)

^g EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NUCLEOPORIN 98; PROTEIN P21; PROTEIN P53;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER PATIENT; CELL DEATH; CELL NUCLEUS; COMPUTER MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; EXOSOME; GENE SILENCING; GENE TARGETING; HOMEOSTASIS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEAR PORE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RNA ANALYSIS; RNA DEGRADATION; WILD TYPE;

14-3-3 PROTEINS; 3' UNTRANSLATED REGIONS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BINDING SITES; CAMPTOTHECIN; CARCINOMA, HEPATOCELLULAR; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EXOSOMES; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, KNOCKOUT; NUCLEAR PORE COMPLEX PROTEINS; P-GLYCOPROTEINS; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 84870932745     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.09.020     Document Type: Article

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