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Volumn 288, Issue 21, 2013, Pages 15085-15097

Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR REPROGRAMMING; EMBRYONIC STEM CELLS; INDUCED PLURIPOTENT STEM CELLS; INTRACELLULAR LOCALIZATION; NUCLEAR IMPORT; NUCLEO-CYTOPLASMIC SHUTTLING; NUCLEOCYTOPLASMIC DYNAMICS; SPATIO-TEMPORAL DYNAMICS;

EID: 84878261274     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.448837     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 0025060177 scopus 로고
    • A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
    • Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M., and Hamada, H. (1990) A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60, 461-472
    • (1990) Cell , vol.60 , pp. 461-472
    • Okamoto, K.1    Okazawa, H.2    Okuda, A.3    Sakai, M.4    Muramatsu, M.5    Hamada, H.6
  • 2
    • 0025352402 scopus 로고
    • A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
    • Rosner, M. H., Vigano, M. A., Ozato, K., Timmons, P. M., Poirier, F., Rigby, P. W., and Staudt, L. M. (1990) A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 345, 686-692
    • (1990) Nature , vol.345 , pp. 686-692
    • Rosner, M.H.1    Vigano, M.A.2    Ozato, K.3    Timmons, P.M.4    Poirier, F.5    Rigby, P.W.6    Staudt, L.M.7
  • 3
    • 0025319004 scopus 로고
    • New type of POU domain in germ line-specific protein Oct-4
    • Schöler, H. R., Ruppert, S., Suzuki, N., Chowdhury, K., and Gruss, P. (1990) New type of POU domain in germ line-specific protein Oct-4. Nature 344, 435-439
    • (1990) Nature , vol.344 , pp. 435-439
    • Schöler, H.R.1    Ruppert, S.2    Suzuki, N.3    Chowdhury, K.4    Gruss, P.5
  • 4
    • 7844233314 scopus 로고    scopus 로고
    • The molecular biology of Oct-4 in the early mouse embryo
    • DOI 10.1093/molehr/4.11.1021
    • Ovitt, C. E., and Schöler, H. R. (1998) The molecular biology of Oct-4 in the early mouse embryo. Mol. Hum. Reprod. 4, 1021-1031 (Pubitemid 28508992)
    • (1998) Molecular Human Reproduction , vol.4 , Issue.11 , pp. 1021-1031
    • Ovitt, C.E.1    Scholar, H.R.2
  • 5
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • DOI 10.1016/S0092-8674(00)81769-9
    • Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H., and Smith, A. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391 (Pubitemid 28507326)
    • (1998) Cell , vol.95 , Issue.3 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5    Chambers, I.6    Scholer, H.7    Smith, A.8
  • 6
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • DOI 10.1038/74199
    • Niwa, H., Miyazaki, J., and Smith, A. G. (2000) Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation, or self-renewal of ES cells. Nat. Genet. 24, 372-376 (Pubitemid 30187435)
    • (2000) Nature Genetics , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.-I.2    Smith, A.G.3
  • 7
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi, K., and Yamanaka, S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 12
    • 55149099432 scopus 로고    scopus 로고
    • Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling
    • Matoba, R., Niwa, H., Masui, S., Ohtsuka, S., Carter, M. G., Sharov, A. A., and Ko, M. S. (2006) Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS ONE 1, e26
    • (2006) PLoS ONE , vol.1
    • Matoba, R.1    Niwa, H.2    Masui, S.3    Ohtsuka, S.4    Carter, M.G.5    Sharov, A.A.6    Ko, M.S.7
  • 13
    • 33846917472 scopus 로고    scopus 로고
    • Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
    • DOI 10.1634/stemcells.2006-0426
    • Babaie, Y., Herwig, R., Greber, B., Brink, T. C., Wruck, W., Groth, D., Lehrach, H., Burdon, T., and Adjaye, J. (2007) Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells 25, 500-510 (Pubitemid 46232806)
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 500-510
    • Babaie, Y.1    Herwig, R.2    Greber, B.3    Brink, T.C.4    Wruck, W.5    Groth, D.6    Lehrach, H.7    Burdon, T.8    Adjaye, J.9
  • 14
    • 40749104852 scopus 로고    scopus 로고
    • An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells
    • DOI 10.1016/j.cell.2008.02.039, PII S0092867408003280
    • Kim, J., Chu, J., Shen, X., Wang, J., and Orkin, S. H. (2008) An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061 (Pubitemid 351381745)
    • (2008) Cell , vol.132 , Issue.6 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 15
    • 0038348295 scopus 로고    scopus 로고
    • Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures
    • DOI 10.1242/dev.00476
    • Shimozaki, K., Nakashima, K., Niwa, H., and Taga, T. (2003) Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development 130, 2505-2512 (Pubitemid 36722400)
    • (2003) Development , vol.130 , Issue.11 , pp. 2505-2512
    • Shimozaki, K.1    Nakashima, K.2    Niwa, H.3    Taga, T.4
  • 16
    • 0037520693 scopus 로고    scopus 로고
    • Stem cell pluripotency and transcription factor Oct4
    • Pan, G. J., Chang, Z. Y., Schöler, H. R., and Pei, D. (2002) Stem cell pluripotency and transcription factor Oct4. Cell Res. 12, 321-329 (Pubitemid 135708344)
    • (2002) Cell Research , vol.12 , Issue.5-6 , pp. 321-329
    • Pan, G.J.1    Chang, Z.Y.I.2    Scholer, H.R.3    Pei, D.4
  • 18
    • 34547113757 scopus 로고    scopus 로고
    • Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation
    • DOI 10.1074/jbc.M611041200
    • Wei, F., Schöler, H. R., and Atchison, M. L. (2007) Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation. J. Biol. Chem. 282, 21551-21560 (Pubitemid 47099909)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.29 , pp. 21551-21560
    • Wei, F.1    Scholer, H.R.2    Atchison, M.L.3
  • 19
    • 84887212474 scopus 로고    scopus 로고
    • Post-translational regulation of Oct4 transcriptional activity
    • Saxe, J. P., Tomilin, A., Schöler, H. R., Plath, K., and Huang, J. (2009) Post-translational regulation of Oct4 transcriptional activity. PLoS ONE 4, e4467
    • (2009) PLoS ONE , vol.4
    • Saxe, J.P.1    Tomilin, A.2    Schöler, H.R.3    Plath, K.4    Huang, J.5
  • 20
    • 59049086847 scopus 로고    scopus 로고
    • Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry
    • Swaney, D. L., Wenger, C. D., Thomson, J. A., and Coon, J. J. (2009) Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry. Proc. Natl. Acad. Sci. U.S.A. 106, 995-1000
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 995-1000
    • Swaney, D.L.1    Wenger, C.D.2    Thomson, J.A.3    Coon, J.J.4
  • 21
    • 0031014396 scopus 로고    scopus 로고
    • The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain
    • Brehm, A., Ohbo, K., and Schöler, H. (1997) The carboxyl-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain. Mol. Cell. Biol. 17, 154-162 (Pubitemid 26425604)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.1 , pp. 154-162
    • Brehm, A.1    Ohbo, K.2    Scholer, H.3
  • 22
    • 4344707501 scopus 로고    scopus 로고
    • Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation
    • DOI 10.1074/jbc.M405117200
    • Pan, G., Qin, B., Liu, N., Schöler, H. R., and Pei, D. (2004) Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation. J. Biol. Chem. 279, 37013-37020 (Pubitemid 39129051)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 37013-37020
    • Pan, G.1    Qin, B.2    Liu, N.3    Scholer, H.R.4    Pei, D.5
  • 24
    • 57749198235 scopus 로고    scopus 로고
    • Identification of karyopherin-α2 as an Oct4 associated protein
    • Li, X., Sun, L., and Jin, Y. (2008) Identification of karyopherin-α2 as an Oct4 associated protein. J. Genet. Genomics 35, 723-728
    • (2008) J. Genet. Genomics , vol.35 , pp. 723-728
    • Li, X.1    Sun, L.2    Jin, Y.3
  • 25
    • 80355148459 scopus 로고    scopus 로고
    • Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells
    • Young, J. C., Major, A. T., Miyamoto, Y., Loveland, K. L., and Jans, D. A. (2011) Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells. FASEB J. 25, 3958-3965
    • (2011) FASEB J. , vol.25 , pp. 3958-3965
    • Young, J.C.1    Major, A.T.2    Miyamoto, Y.3    Loveland, K.L.4    Jans, D.A.5
  • 26
    • 28544446112 scopus 로고    scopus 로고
    • The POU protein Oct-6 is a nucleocytoplasmic shuttling protein
    • DOI 10.1093/nar/gki947
    • Baranek, C., Sock, E., and Wegner, M. (2005) The POU protein Oct-6 is a nucleocytoplasmic shuttling protein. Nucleic Acids Res. 33, 6277-6286 (Pubitemid 41742565)
    • (2005) Nucleic Acids Research , vol.33 , Issue.19 , pp. 6277-6286
    • Baranek, C.1    Sock, E.2    Wegner, M.3
  • 27
    • 33750433896 scopus 로고    scopus 로고
    • Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition
    • DOI 10.1534/genetics.106.060244
    • Urasaki, A., Morvan, G., and Kawakami, K. (2006) Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition. Genetics 174, 639-649 (Pubitemid 44656456)
    • (2006) Genetics , vol.174 , Issue.2 , pp. 639-649
    • Urasaki, A.1    Morvan, G.2    Kawakami, K.3
  • 28
    • 77955274497 scopus 로고    scopus 로고
    • Effective culture conditions for the induction of pluripotent stem cells
    • Okada, M., Oka, M., and Yoneda, Y. (2010) Effective culture conditions for the induction of pluripotent stem cells. Biochim. Biophys. Acta 1800, 956-963
    • (2010) Biochim. Biophys. Acta , vol.1800 , pp. 956-963
    • Okada, M.1    Oka, M.2    Yoneda, Y.3
  • 29
    • 0029124988 scopus 로고
    • The POU domain. Versatility in transcriptional regulation by a flexible two-in-one DNA binding domain
    • Herr, W., and Cleary, M. A. (1995) The POU domain. Versatility in transcriptional regulation by a flexible two-in-one DNA binding domain. Genes Dev. 9, 1679-1693
    • (1995) Genes Dev. , vol.9 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 30
    • 0034837080 scopus 로고    scopus 로고
    • Molecular mechanism to maintain stem cell renewal of ES cells
    • Niwa, H. (2001) Molecular mechanism to maintain stem cell renewal of ES cells. Cell Struct. Funct. 26, 137-148
    • (2001) Cell Struct. Funct. , vol.26 , pp. 137-148
    • Niwa, H.1
  • 32
    • 79551601441 scopus 로고    scopus 로고
    • Oct4 kinetics predict cell lineage patterning in the early mammalian embryo
    • Plachta, N., Bollenbach, T., Pease, S., Fraser, S. E., and Pantazis, P. (2011) Oct4 kinetics predict cell lineage patterning in the early mammalian embryo. Nat. Cell Biol. 13, 117-123
    • (2011) Nat. Cell Biol. , vol.13 , pp. 117-123
    • Plachta, N.1    Bollenbach, T.2    Pease, S.3    Fraser, S.E.4    Pantazis, P.5
  • 33
    • 1642367850 scopus 로고    scopus 로고
    • Transposition of the Tol2 Element, an Ac-Like Element from the Japanese Medaka Fish Oryzias latipes, in Mouse Embryonic Stem Cells
    • DOI 10.1534/genetics.166.2.895
    • Kawakami, K., and Noda, T. (2004) Transposition of the Tol2 element, an Ac-like element from the Japanese medaka fish Oryzias latipes, in mouse embryonic stem cells. Genetics 166, 895-899 (Pubitemid 38391749)
    • (2004) Genetics , vol.166 , Issue.2 , pp. 895-899
    • Kawakami, K.1    Noda, T.2
  • 35
    • 14844359620 scopus 로고    scopus 로고
    • Octamer and sox elements are required for transcriptional cis regulation of Nanog gene expression
    • DOI 10.1128/MCB.25.6.2475-2485.2005
    • Kuroda, T., Tada, M., Kubota, H., Kimura, H., Hatano, S. Y., Suemori, H., Nakatsuji, N., and Tada, T. (2005) Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol. Cell. Biol. 25, 2475-2485 (Pubitemid 40354640)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.6 , pp. 2475-2485
    • Kuroda, T.1    Tada, M.2    Kubota, H.3    Kimura, H.4    Hatano, S.-Y.5    Suemori, H.6    Nakatsuji, N.7    Tada, T.8
  • 36
    • 44649086468 scopus 로고    scopus 로고
    • Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
    • DOI 10.1038/ncb1736, PII NCB1736
    • Liang, J., Wan, M., Zhang, Y., Gu, P., Xin, H., Jung, S. Y., Qin, J., Wong, J., Cooney, A. J., Liu, D., and Songyang, Z. (2008) Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat. Cell Biol. 10, 731-739 (Pubitemid 351772939)
    • (2008) Nature Cell Biology , vol.10 , Issue.6 , pp. 731-739
    • Liang, J.1    Wan, M.2    Zhang, Y.3    Gu, P.4    Xin, H.5    Jung, S.Y.6    Qin, J.7    Wong, J.8    Cooney, A.J.9    Liu, D.10    Songyang, Z.11
  • 37
    • 77949881949 scopus 로고    scopus 로고
    • An expanded Oct4 interaction network. Implications for stem cell biology, development, and disease
    • Pardo, M., Lang, B., Yu, L., Prosser, H., Bradley, A., Babu, M. M., and Choudhary, J. (2010) An expanded Oct4 interaction network. Implications for stem cell biology, development, and disease. Cell Stem Cell 6, 382-395
    • (2010) Cell Stem Cell , vol.6 , pp. 382-395
    • Pardo, M.1    Lang, B.2    Yu, L.3    Prosser, H.4    Bradley, A.5    Babu, M.M.6    Choudhary, J.7
  • 40
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • DOI 10.1038/nbt1418, PII NBT1418
    • Huangfu, D., Maehr, R., Guo, W., Eijkelenboom, A., Snitow, M., Chen, A. E., and Melton, D. A. (2008) Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 26, 795-797 (Pubitemid 351961456)
    • (2008) Nature Biotechnology , vol.26 , Issue.7 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6    Melton, D.A.7
  • 42
    • 44349103591 scopus 로고    scopus 로고
    • A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells
    • DOI 10.1016/j.stem.2008.05.011, PII S1934590908002257
    • Shi, Y., Do, J. T., Desponts, C., Hahm, H. S., Schöler, H. R., and Ding, S. (2008) A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2, 525-528 (Pubitemid 351729222)
    • (2008) Cell Stem Cell , vol.2 , Issue.6 , pp. 525-528
    • Shi, Y.1    Tae, D.J.2    Desponts, C.3    Hahm, H.S.4    Scholer, H.R.5    Ding, S.6
  • 44
    • 77955501968 scopus 로고    scopus 로고
    • Butyrate promotes induced pluripotent stem cell generation
    • Liang, G., Taranova, O., Xia, K., and Zhang, Y. (2010) Butyrate promotes induced pluripotent stem cell generation. J. Biol. Chem. 285, 25516-25521
    • (2010) J. Biol. Chem. , vol.285 , pp. 25516-25521
    • Liang, G.1    Taranova, O.2    Xia, K.3    Zhang, Y.4
  • 48
    • 84870058502 scopus 로고    scopus 로고
    • Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
    • Soufi, A., Donahue, G., and Zaret, K. S. (2012) Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 151, 994-1004
    • (2012) Cell , vol.151 , pp. 994-1004
    • Soufi, A.1    Donahue, G.2    Zaret, K.S.3


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