The serine protease hepsin mediates urinary secretion and polymerisation of zona pellucida domain protein uromodulin

eLife

Volumn 4, Issue DECEMBER2015, 2015, Pages

  Brunati, Martina ^a   Perucca, Simone ^a   Han, Ling ^b   Cattaneo, Angela ^a,c   Consolato, Francesco ^a   Andolfo, Annapaola ^a   Schaeffer, Céline ^a   Olinger, Eric ^d   Peng, Jianhao ^e   Santambrogio, Sara ^a   Perrier, Romain ^f   Li, Shuo ^e   Bokhove, Marcel ^b   Bachi, Angela ^a,c   Hummler, Edith ^f   Devuyst, Olivier ^d   Wu, Qingyu ^e   Jovine, Luca ^b   Rampoldi, Luca ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e LERNER RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HEPSIN; PROSTASIN; TAMM HORSFALL GLYCOPROTEIN; SERINE PROTEINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; URINARY EXCRETION; WESTERN BLOTTING; ZONA PELLUCIDA; ANIMAL; CELL LINE; DOG; KNOCKOUT MOUSE; METABOLISM; PROTEIN DEGRADATION; PROTEIN MULTIMERIZATION; SECRETION (PROCESS);

ANIMALS; CELL LINE; DOGS; HUMANS; MICE, KNOCKOUT; PROTEIN MULTIMERIZATION; PROTEOLYSIS; SERINE ENDOPEPTIDASES; UROMODULIN;

EID: 84956957059     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.08887     Document Type: Article

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