Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease

Journal of Clinical Investigation

Volumn 101, Issue 2, 1998, Pages 321-326

  Wu, Qingyu ^a   Yu, Dongyin ^a   Post, Joseph ^a   Halks Miller, Meredith ^a   Sadler, J Evan ^b   Morser, John ^a  

^a BAYER AG   (Germany)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Embryonic stem cells; Factor VII; Gene targeting; Hepatocyte; Homologous recombination

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; LIPOPOLYSACCHARIDE; SERINE PROTEINASE; THROMBOPLASTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BLOOD CLOTTING TIME; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; EMBRYO; EMBRYO DEVELOPMENT; ENZYME DEFICIENCY; FEMALE; GENE TARGETING; GENETIC RECOMBINATION; HEMOSTASIS; HOMOZYGOSITY; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032518561     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1617     Document Type: Article

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