Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

Bioscience Reports

Volumn 36, Issue 1, 2016, Pages

  Arnež, Katja Hrovat ^a   Kindlova, Michaela ^b   Bokil, Nilesh J ^b   Murphy, James M ^c,d   Sweet, Matthew J ^b   Gunčar, Gregor ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cell death; Isoform; Macrophage; Mixed lineage kinase domain like; MLKL; Necroptosis

Indexed keywords

AMINO ACID; ISOENZYME; MIXED LINEAGE KINASE DOMAIN LIKE PSEUDOKINASE; MLKL ISOFORM 1; MLKL ISOFORM 2; PROTEIN KINASE; UNCLASSIFIED DRUG; MLKL PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; HEK293 CELL LINE; HUMAN; HUMAN CELL; MACROPHAGE; NECROPTOSIS; PREDICTION; PROTEIN EXPRESSION; STIMULUS RESPONSE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; MOLECULAR MODEL; NECROSIS; PATHOLOGY; PROTEIN TERTIARY STRUCTURE;

CELL SURVIVAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HUMANS; ISOENZYMES; MACROPHAGES; MODELS, MOLECULAR; NECROSIS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY;

EID: 84956949392     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20150246     Document Type: Article

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