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Volumn 1860, Issue 4, 2016, Pages 765-774

Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice

Author keywords

Actin; Adherens junction; Alcohol; Claudin; Fatty liver; Tight junction

Indexed keywords

ALCOHOL; AMINOTRANSFERASE; BETA CATENIN; FLUORESCEIN ISOTHIOCYANATE; INULIN; OCCLUDIN; PROTEIN ZO1; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL; UVOMORULIN; OCLN PROTEIN, HUMAN; OCLN PROTEIN, MOUSE;

EID: 84956906927     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.12.013     Document Type: Article
Times cited : (99)

References (37)
  • 1
    • 68949178506 scopus 로고    scopus 로고
    • Endotoxemia and gut barrier dysfunction in alcoholic liver disease
    • R. Rao Endotoxemia and gut barrier dysfunction in alcoholic liver disease Hepatology 50 2009 638 644
    • (2009) Hepatology , vol.50 , pp. 638-644
    • Rao, R.1
  • 2
    • 2642553874 scopus 로고    scopus 로고
    • Recent advances in alcoholic liver disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease
    • R.K. Rao, A. Seth, and P. Sheth Recent advances in alcoholic liver disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease Am. J. Physiol. Gastrointest. Liver Physiol. 286 2004 G881 G884
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.286 , pp. G881-G884
    • Rao, R.K.1    Seth, A.2    Sheth, P.3
  • 3
    • 0034967963 scopus 로고    scopus 로고
    • Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial
    • K.J. Atkinson, and R.K. Rao Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial Am. J. Physiol. Gastrointest. Liver Physiol. 280 2001 G1280 G1288
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.280 , pp. G1280-G1288
    • Atkinson, K.J.1    Rao, R.K.2
  • 4
    • 0032938095 scopus 로고    scopus 로고
    • Ethanol modulation of intestinal epithelial tight junction barrier
    • T.Y. Ma, D. Nguyen, V. Bui, H. Nguyen, and N. Hoa Ethanol modulation of intestinal epithelial tight junction barrier Am. J. Phys. 276 1999 G965 G974
    • (1999) Am. J. Phys. , vol.276 , pp. G965-G974
    • Ma, T.Y.1    Nguyen, D.2    Bui, V.3    Nguyen, H.4    Hoa, N.5
  • 5
    • 33847743407 scopus 로고    scopus 로고
    • Acetaldehyde dissociates the PTP1B-E-cadherin-beta-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism
    • P. Sheth, A. Seth, K.J. Atkinson, T. Gheyi, G. Kale, F. Giorgianni, D.M. Desiderio, C. Li, A. Naren, and R. Rao Acetaldehyde dissociates the PTP1B-E-cadherin-beta-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism Biochem. J. 402 2007 291 300
    • (2007) Biochem. J. , vol.402 , pp. 291-300
    • Sheth, P.1    Seth, A.2    Atkinson, K.J.3    Gheyi, T.4    Kale, G.5    Giorgianni, F.6    Desiderio, D.M.7    Li, C.8    Naren, A.9    Rao, R.10
  • 6
    • 41249094587 scopus 로고    scopus 로고
    • Role of phospholipase Cgamma-induced activation of protein kinase Cepsilon (PKCepsilon) and PKCbetaI in epidermal growth factor-mediated protection of from acetaldehyde in Caco-2 cell monolayers
    • T. Suzuki, A. Seth, and R. Rao Role of phospholipase Cgamma-induced activation of protein kinase Cepsilon (PKCepsilon) and PKCbetaI in epidermal growth factor-mediated protection of from acetaldehyde in Caco-2 cell monolayers J. Biol. Chem. 283 2008 3574 3583
    • (2008) J. Biol. Chem. , vol.283 , pp. 3574-3583
    • Suzuki, T.1    Seth, A.2    Rao, R.3
  • 8
    • 84856810398 scopus 로고    scopus 로고
    • Occludin: One protein, many forms
    • P.M. Cummins Occludin: one protein, many forms Mol. Cell. Biol. 32 2012 242 250
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 242-250
    • Cummins, P.M.1
  • 9
    • 79959736965 scopus 로고    scopus 로고
    • Protein kinase Czeta phosphorylates occludin and promotes assembly of epithelial
    • S. Jain, T. Suzuki, A. Seth, G. Samak, and R. Rao Protein kinase Czeta phosphorylates occludin and promotes assembly of epithelial Biochem. J. 437 2011 289 299
    • (2011) Biochem. J. , vol.437 , pp. 289-299
    • Jain, S.1    Suzuki, T.2    Seth, A.3    Samak, G.4    Rao, R.5
  • 10
    • 67249146480 scopus 로고    scopus 로고
    • Occludin phosphorylation in regulation of epithelial
    • R. Rao Occludin phosphorylation in regulation of epithelial Ann. N. Y. Acad. Sci. 1165 2009 62 68
    • (2009) Ann. N. Y. Acad. Sci. , vol.1165 , pp. 62-68
    • Rao, R.1
  • 12
    • 52049083402 scopus 로고    scopus 로고
    • Oxidative stress-induced disruption of epithelial and endothelial
    • R. Rao Oxidative stress-induced disruption of epithelial and endothelial Front. Biosci. 13 2008 7210 7226
    • (2008) Front. Biosci. , vol.13 , pp. 7210-7226
    • Rao, R.1
  • 15
    • 36249014842 scopus 로고    scopus 로고
    • Regulation of tight junction proteins occludin and claudin 5 in the primate ovary during the ovulatory cycle and after inhibition of vascular endothelial growth factor
    • M. Rodewald, D. Herr, H.M. Fraser, G. Hack, R. Kreienberg, and C. Wulff Regulation of tight junction proteins occludin and claudin 5 in the primate ovary during the ovulatory cycle and after inhibition of vascular endothelial growth factor Mol. Hum. Reprod. 13 2007 781 789
    • (2007) Mol. Hum. Reprod. , vol.13 , pp. 781-789
    • Rodewald, M.1    Herr, D.2    Fraser, H.M.3    Hack, G.4    Kreienberg, R.5    Wulff, C.6
  • 19
    • 0036901407 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress
    • R.K. Rao, S. Basuroy, V.U. Rao, K.J. Karnaky Jr.; and A. Gupta Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress Biochem. J. 368 2002 471 481
    • (2002) Biochem. J. , vol.368 , pp. 471-481
    • Rao, R.K.1    Basuroy, S.2    Rao, V.U.3    Karnaky, K.J.4    Gupta, A.5
  • 20
    • 0030869798 scopus 로고    scopus 로고
    • Oxidant-induced disruption of intestinal epithelial barrier function: Role of protein tyrosine phosphorylation
    • R.K. Rao, R.D. Baker, S.S. Baker, A. Gupta, and M. Holycross Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation Am. J. Physiol. 273 1997 G812 G823
    • (1997) Am. J. Physiol. , vol.273 , pp. G812-G823
    • Rao, R.K.1    Baker, R.D.2    Baker, S.S.3    Gupta, A.4    Holycross, M.5
  • 21
    • 84901932901 scopus 로고    scopus 로고
    • Tributyrin supplementation protects mice from acute ethanol-induced gut injury
    • G.A. Cresci, K. Bush, and L.E. Nagy Tributyrin supplementation protects mice from acute ethanol-induced gut injury Alcohol. Clin. Exp. Res. 38 2014 1489 1501
    • (2014) Alcohol. Clin. Exp. Res. , vol.38 , pp. 1489-1501
    • Cresci, G.A.1    Bush, K.2    Nagy, L.E.3
  • 22
    • 83255189411 scopus 로고    scopus 로고
    • Alteration in intestine tight junction protein phosphorylation and apoptosis is associated with increase in IL-18 levels following alcohol intoxication and burn injury
    • X. Li, S. Akhtar, and M.A. Choudhry Alteration in intestine tight junction protein phosphorylation and apoptosis is associated with increase in IL-18 levels following alcohol intoxication and burn injury Biochim. Biophys. Acta 1822 2012 196 203
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 196-203
    • Li, X.1    Akhtar, S.2    Choudhry, M.A.3
  • 23
    • 84924548354 scopus 로고    scopus 로고
    • Inhibition of miR122a by Lactobacillus rhamnosus GG culture supernatant increases intestinal occludin expression and protects mice from alcoholic liver disease
    • H. Zhao, C. Zhao, Y. Dong, M. Zhang, Y. Wang, F. Li, X. Li, C. McClain, S. Yang, and W. Feng Inhibition of miR122a by Lactobacillus rhamnosus GG culture supernatant increases intestinal occludin expression and protects mice from alcoholic liver disease Toxicol. Lett. 234 2015 194 200
    • (2015) Toxicol. Lett. , vol.234 , pp. 194-200
    • Zhao, H.1    Zhao, C.2    Dong, Y.3    Zhang, M.4    Wang, Y.5    Li, F.6    Li, X.7    McClain, C.8    Yang, S.9    Feng, W.10
  • 26
    • 84969388080 scopus 로고    scopus 로고
    • Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice
    • K.K. Chaudhry, P.K. Shukla, H. Mir, B. Manda, R. Gangwar, N. Yadav, M. McMullen, L.E. Nagy, and R. Rao Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice J. Nutr. Biochem. 2015
    • (2015) J. Nutr. Biochem.
    • Chaudhry, K.K.1    Shukla, P.K.2    Mir, H.3    Manda, B.4    Gangwar, R.5    Yadav, N.6    McMullen, M.7    Nagy, L.E.8    Rao, R.9
  • 27
    • 0031761303 scopus 로고    scopus 로고
    • Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayers
    • R.K. Rao Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayers Alcohol. Clin. Exp. Res. 22 1998 1724 1730
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 1724-1730
    • Rao, R.K.1
  • 28
    • 77956997586 scopus 로고    scopus 로고
    • C-Jun NH2-terminal kinase-2 mediates osmotic stress-induced tight junction disruption in the intestinal epithelium
    • G. Samak, T. Suzuki, A. Bhargava, and R.K. Rao c-Jun NH2-terminal kinase-2 mediates osmotic stress-induced tight junction disruption in the intestinal epithelium Am. J. Physiol. Gastrointest. Liver Physiol. 299 2010 G572 G584
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.299 , pp. G572-G584
    • Samak, G.1    Suzuki, T.2    Bhargava, A.3    Rao, R.K.4
  • 29
    • 22544451542 scopus 로고    scopus 로고
    • Acetaldehyde disrupts and adherens junctions in human colonic mucosa: Protection by EGF and L-glutamine
    • S. Basuroy, P. Sheth, C.M. Mansbach, and R.K. Rao Acetaldehyde disrupts and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine Am. J. Physiol. Gastrointest. Liver Physiol. 289 2005 G367 G375
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.289 , pp. G367-G375
    • Basuroy, S.1    Sheth, P.2    Mansbach, C.M.3    Rao, R.K.4
  • 30
    • 0033521140 scopus 로고    scopus 로고
    • Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3
    • E.S. Wittchen, J. Haskins, and B.R. Stevenson Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3 J. Biol. Chem. 274 1999 35179 35185
    • (1999) J. Biol. Chem. , vol.274 , pp. 35179-35185
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 31
    • 84871318385 scopus 로고    scopus 로고
    • Acetaldehyde disrupts in Caco-2 cell monolayers by a protein phosphatase 2A-dependent mechanism
    • M. Dunagan, K. Chaudhry, G. Samak, and R.K. Rao Acetaldehyde disrupts in Caco-2 cell monolayers by a protein phosphatase 2A-dependent mechanism Am. J. Physiol. Gastrointest. Liver Physiol. 303 2012 G1356 G1364
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.303 , pp. G1356-G1364
    • Dunagan, M.1    Chaudhry, K.2    Samak, G.3    Rao, R.K.4
  • 33
    • 84860433691 scopus 로고    scopus 로고
    • The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease
    • I.A. Kirpich, W. Feng, Y. Wang, Y. Liu, D.F. Barker, S.S. Barve, and C.J. McClain The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease Alcohol. Clin. Exp. Res. 36 2012 835 846
    • (2012) Alcohol. Clin. Exp. Res. , vol.36 , pp. 835-846
    • Kirpich, I.A.1    Feng, W.2    Wang, Y.3    Liu, Y.4    Barker, D.F.5    Barve, S.S.6    McClain, C.J.7
  • 34
    • 84872724877 scopus 로고    scopus 로고
    • Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14
    • S. Guo, R. Al-Sadi, H.M. Said, and T.Y. Ma Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14 Am. J. Pathol. 182 2013 375 387
    • (2013) Am. J. Pathol. , vol.182 , pp. 375-387
    • Guo, S.1    Al-Sadi, R.2    Said, H.M.3    Ma, T.Y.4
  • 35
    • 84913551633 scopus 로고    scopus 로고
    • Claudin interactions in and out of the tight junction
    • C.M. Van Itallie, and J.M. Anderson Claudin interactions in and out of the tight junction Tissue Barriers 1 2013 e25247
    • (2013) Tissue Barriers , vol.1
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 36
    • 33645963995 scopus 로고    scopus 로고
    • Claudins and epithelial paracellular transport
    • C.M. Van Itallie, and J.M. Anderson Claudins and epithelial paracellular transport Annu. Rev. Physiol. 68 2006 403 429
    • (2006) Annu. Rev. Physiol. , vol.68 , pp. 403-429
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 37
    • 0024095524 scopus 로고
    • The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
    • B. Gumbiner, B. Stevenson, and A. Grimaldi The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex J. Cell Biol. 107 1988 1575 1587
    • (1988) J. Cell Biol. , vol.107 , pp. 1575-1587
    • Gumbiner, B.1    Stevenson, B.2    Grimaldi, A.3


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