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Angewandte Chemie - International Edition

Volumn 55, Issue 10, 2016, Pages 3318-3322

19FNMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis

(5) Jin, Yi a Molt, Robert W b Waltho, Jonathan P a,b,c Richards, Nigel G J d Blackburn, G Michael a

a UNIVERSITY OF SHEFFIELD (United Kingdom)

b INDIANA UNIVERSITY (United States)

c UNIVERSITY OF MANCHESTER (United Kingdom)

d CARDIFF UNIVERSITY (United Kingdom)

Author keywords

19FNMR; enzyme catalysis; GTP hydrolases; phosphoryl transfer; reaction mechanisms

Indexed keywords

CATALYSIS; CHEMICAL BONDS; COMPLEX NETWORKS; COORDINATION REACTIONS; ELECTRONIC PROPERTIES; ENZYMES; GROUND STATE; HYDROLYSIS; MAGNESIUM;

19FNMR; ELECTRON DISTRIBUTIONS; ELECTRONIC TRANSITION; ENZYME CATALYSIS; GENERAL BASE CATALYSIS; PHOSPHORYL TRANSFER; REACTION MECHANISM; TRANSITION-STATE ANALOGUES;

HYDROGEN BONDS;

FLUORINE; GUANOSINE TRIPHOSPHATE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

HYDROLYSIS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES;

FLUORINE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; RHOA GTP-BINDING PROTEIN;

EID: 84956863037 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201509477 Document Type: Article

Times cited : (23)

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