메뉴 건너뛰기




Volumn 12, Issue 1, 2016, Pages

Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; C REACTIVE PROTEIN; RIFAXIMIN; SALAZOSULFAPYRIDINE; THROMBOPLASTIN; ANTIINFECTIVE AGENT; RIFAMYCIN;

EID: 84956730438     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005384     Document Type: Article
Times cited : (37)

References (89)
  • 1
    • 63449124466 scopus 로고    scopus 로고
    • Emerging concepts in the immunopathogenesis of AIDS
    • Douek DC, Roederer M, Koup RA, (2009) Emerging concepts in the immunopathogenesis of AIDS. Annu Rev Med 60: 471–484. doi: 10.1146/annurev.med.60.041807.123549 18947296
    • (2009) Annu Rev Med , vol.60 , pp. 471-484
    • Douek, D.C.1    Roederer, M.2    Koup, R.A.3
  • 2
    • 0038417311 scopus 로고    scopus 로고
    • Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover
    • Anthony KB, Yoder C, Metcalf JA, DerSimonian R, Orenstein JM, et al. (2003) Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover. J Acquir Immune Defic Syndr 33: 125–133. 12794543
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 125-133
    • Anthony, K.B.1    Yoder, C.2    Metcalf, J.A.3    DerSimonian, R.4    Orenstein, J.M.5
  • 3
    • 79551614790 scopus 로고    scopus 로고
    • HIV infection, inflammation, immunosenescence, and aging
    • Deeks SG, (2011) HIV infection, inflammation, immunosenescence, and aging. Annu Rev Med 62: 141–155. doi: 10.1146/annurev-med-042909-093756 21090961
    • (2011) Annu Rev Med , vol.62 , pp. 141-155
    • Deeks, S.G.1
  • 4
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, Bredt B, Hagos E, et al. (2003) T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 187: 1534–1543. 12721933
    • (2003) J Infect Dis , vol.187 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3    Bredt, B.4    Hagos, E.5
  • 5
    • 79960011656 scopus 로고    scopus 로고
    • Immunodeficiency lentiviral infections in natural and non-natural hosts
    • Brenchley JM, Paiardini M, (2011) Immunodeficiency lentiviral infections in natural and non-natural hosts. Blood 118: 847–854. doi: 10.1182/blood-2010-12-325936 21505193
    • (2011) Blood , vol.118 , pp. 847-854
    • Brenchley, J.M.1    Paiardini, M.2
  • 6
    • 77249139150 scopus 로고    scopus 로고
    • Where the wild things are: Pathogenesis of SIV infection in African nonhuman primate hosts
    • Pandrea I, Apetrei C, (2010) Where the wild things are: Pathogenesis of SIV infection in African nonhuman primate hosts. Curr HIV/AIDS Reports 7: 28–36. doi: 10.1007/s11904-009-0034-8 20425055
    • (2010) Curr HIV/AIDS Reports , vol.7 , pp. 28-36
    • Pandrea, I.1    Apetrei, C.2
  • 8
    • 49849088558 scopus 로고    scopus 로고
    • Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts
    • Pandrea I, Sodora DL, Silvestri G, Apetrei C, (2008) Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts. Trends Immunol 29: 419–428. doi: 10.1016/j.it.2008.05.004 18676179
    • (2008) Trends Immunol , vol.29 , pp. 419-428
    • Pandrea, I.1    Sodora, D.L.2    Silvestri, G.3    Apetrei, C.4
  • 9
    • 33750088152 scopus 로고    scopus 로고
    • Going wild: Lessons from T-lymphotropic naturally occurring lentiviruses
    • VandeWoude S, Apetrei C, (2006) Going wild: Lessons from T-lymphotropic naturally occurring lentiviruses. Clin Microbiol Rev 19: 728–762. 17041142
    • (2006) Clin Microbiol Rev , vol.19 , pp. 728-762
    • VandeWoude, S.1    Apetrei, C.2
  • 10
    • 33745945059 scopus 로고    scopus 로고
    • Simian immunodeficiency viruses replication dynamics in African non-human primate hosts: common patterns and species-specific differences
    • Pandrea I, Silvestri G, Onanga R, Veazey RS, Marx PA, et al. (2006) Simian immunodeficiency viruses replication dynamics in African non-human primate hosts: common patterns and species-specific differences. J Med Primatol 35: 194–201. 16872282
    • (2006) J Med Primatol , vol.35 , pp. 194-201
    • Pandrea, I.1    Silvestri, G.2    Onanga, R.3    Veazey, R.S.4    Marx, P.A.5
  • 11
    • 84875079117 scopus 로고    scopus 로고
    • SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations
    • Ma D, Jasinska A, Kristoff J, Grobler JP, Turner T, et al. (2013) SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations. PLoS Pathog 9: e1003011. doi: 10.1371/journal.ppat.1003011 23349627
    • (2013) PLoS Pathog , vol.9 , pp. 1003011
    • Ma, D.1    Jasinska, A.2    Kristoff, J.3    Grobler, J.P.4    Turner, T.5
  • 12
    • 70349733184 scopus 로고    scopus 로고
    • Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host
    • Gaufin T, Pattison M, Gautam R, Stoulig C, Dufour J, et al. (2009) Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host. J Virol 83: 10347–10357. doi: 10.1128/JVI.00880-09 19656874
    • (2009) J Virol , vol.83 , pp. 10347-10357
    • Gaufin, T.1    Pattison, M.2    Gautam, R.3    Stoulig, C.4    Dufour, J.5
  • 13
    • 77951950465 scopus 로고    scopus 로고
    • Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication
    • Gaufin T, Ribeiro RM, Gautam R, Dufour J, Mandell D, et al. (2010) Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication. Retrovirology 7: 42. doi: 10.1186/1742-4690-7-42 20459829
    • (2010) Retrovirology , vol.7 , pp. 42
    • Gaufin, T.1    Ribeiro, R.M.2    Gautam, R.3    Dufour, J.4    Mandell, D.5
  • 14
    • 84855846939 scopus 로고    scopus 로고
    • Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx)
    • Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, et al. (2011) Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx). J Virol 85: 13077–13087. doi: 10.1128/JVI.05693-11 21957286
    • (2011) J Virol , vol.85 , pp. 13077-13087
    • Apetrei, C.1    Sumpter, B.2    Souquiere, S.3    Chahroudi, A.4    Makuwa, M.5
  • 15
    • 34547099802 scopus 로고    scopus 로고
    • Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys
    • Apetrei C, Gautam R, Sumpter B, Carter AC, Gaufin T, et al. (2007) Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys. J Virol 81: 7913–7923. 17507488
    • (2007) J Virol , vol.81 , pp. 7913-7923
    • Apetrei, C.1    Gautam, R.2    Sumpter, B.3    Carter, A.C.4    Gaufin, T.5
  • 16
    • 84902124658 scopus 로고    scopus 로고
    • Early blockade of microbial translocation positively impacts the natural history of SIV infection
    • Kristoff J, Haret-Richter G, Ma D, Ribeiro RM, Xu C, et al. (2014) Early blockade of microbial translocation positively impacts the natural history of SIV infection. J Clin Invest 124: 2802–2806.
    • (2014) J Clin Invest , vol.124 , pp. 2802-2806
    • Kristoff, J.1    Haret-Richter, G.2    Ma, D.3    Ribeiro, R.M.4    Xu, C.5
  • 17
    • 84901301540 scopus 로고    scopus 로고
    • Determinants of increased pathogenicity upon simian immunodeficiency virus cross-species transmission from natural hosts
    • Mandell D, Kristoff J, Gaufin T, Gautam R, Ma D, et al. (2014) Determinants of increased pathogenicity upon simian immunodeficiency virus cross-species transmission from natural hosts. J Virol 88: 6778–6792.
    • (2014) J Virol , vol.88 , pp. 6778-6792
    • Mandell, D.1    Kristoff, J.2    Gaufin, T.3    Gautam, R.4    Ma, D.5
  • 18
    • 84887309874 scopus 로고    scopus 로고
    • Kinetics of myeloid dendritic cell trafficking and activation: Impact on progressive, nonprogressive and controlled SIV infections
    • Wijewardana V, Kristoff J, Xu C, Ma D, Haret-Richter G, et al. (2013) Kinetics of myeloid dendritic cell trafficking and activation: Impact on progressive, nonprogressive and controlled SIV infections. PLoS Pathog 9: e1003600. doi: 10.1371/journal.ppat.1003600 24098110
    • (2013) PLoS Pathog , vol.9 , pp. 1003600
    • Wijewardana, V.1    Kristoff, J.2    Xu, C.3    Ma, D.4    Haret-Richter, G.5
  • 19
    • 84864345953 scopus 로고    scopus 로고
    • Towards an HIV cure: a global scientific strategy
    • International AIDS Society Scientific Working Group on HIV CureDeeks SG, Autran B, Berkhout B, Benkirane M, et al. (2012) Towards an HIV cure: a global scientific strategy. Nat Rev Immunol 12: 607–614. doi: 10.1038/nri3262 22814509
    • (2012) Nat Rev Immunol , vol.12 , pp. 607-614
    • Deeks, S.G.1    Autran, B.2    Berkhout, B.3    Benkirane, M.4
  • 20
    • 79954449242 scopus 로고    scopus 로고
    • A simian immunodeficiency virus macaque model of highly active antiretroviral treatment: viral latency in the periphery and the central nervous system
    • Clements JE, Gama L, Graham DR, Mankowski JL, Zink MC, (2011) A simian immunodeficiency virus macaque model of highly active antiretroviral treatment: viral latency in the periphery and the central nervous system. Curr Opin HIV AIDS 6: 37–42. doi: 10.1097/COH.0b013e3283412413 21242892
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 37-42
    • Clements, J.E.1    Gama, L.2    Graham, D.R.3    Mankowski, J.L.4    Zink, M.C.5
  • 21
    • 84886790685 scopus 로고    scopus 로고
    • The end of AIDS: HIV infection as a chronic disease
    • Deeks SG, Lewin SR, Havlir DV, (2013) The end of AIDS: HIV infection as a chronic disease. Lancet 382: 1525–1533. doi: 10.1016/S0140-6736(13)61809-7 24152939
    • (2013) Lancet , vol.382 , pp. 1525-1533
    • Deeks, S.G.1    Lewin, S.R.2    Havlir, D.V.3
  • 22
    • 84859399981 scopus 로고    scopus 로고
    • Microbial translocation across the GI tract
    • Brenchley JM, Douek DC, (2012) Microbial translocation across the GI tract. Annu Rev Immunol 30: 149–173. doi: 10.1146/annurev-immunol-020711-075001 22224779
    • (2012) Annu Rev Immunol , vol.30 , pp. 149-173
    • Brenchley, J.M.1    Douek, D.C.2
  • 23
    • 33645924682 scopus 로고    scopus 로고
    • HIV disease: fallout from a mucosal catastrophe?
    • Brenchley JM, Price DA, Douek DC, (2006) HIV disease: fallout from a mucosal catastrophe? Nat Immunol 7: 235–239. 16482171
    • (2006) Nat Immunol , vol.7 , pp. 235-239
    • Brenchley, J.M.1    Price, D.A.2    Douek, D.C.3
  • 24
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, et al. (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 12: 1365–1371. 17115046
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3    Asher, T.E.4    Silvestri, G.5
  • 25
    • 84865163472 scopus 로고    scopus 로고
    • Microbial translocation in HIV infection: causes, consequences and treatment opportunities
    • Sandler NG, Douek DC, (2012) Microbial translocation in HIV infection: causes, consequences and treatment opportunities. Nat Rev Microbiol 10: 655–666. doi: 10.1038/nrmicro2848 22886237
    • (2012) Nat Rev Microbiol , vol.10 , pp. 655-666
    • Sandler, N.G.1    Douek, D.C.2
  • 26
    • 35448976736 scopus 로고    scopus 로고
    • Severe depletion of mucosal CD4+ T cells in AIDS-free SIV-infected sooty mangabeys
    • Gordon S, Klatt NR, Milush JM, Engram J, Dunham RM, et al. (2007) Severe depletion of mucosal CD4+ T cells in AIDS-free SIV-infected sooty mangabeys. J Immunol 179: 3026–3034.
    • (2007) J Immunol , vol.179 , pp. 3026-3034
    • Gordon, S.1    Klatt, N.R.2    Milush, J.M.3    Engram, J.4    Dunham, R.M.5
  • 27
    • 36048989052 scopus 로고    scopus 로고
    • Acute loss of intestinal CD4+ T cells is not predictive of SIV virulence
    • Pandrea I, Gautam R, Ribeiro R, Brenchley JM, Butler IF, et al. (2007) Acute loss of intestinal CD4+ T cells is not predictive of SIV virulence. J Immunol 179: 3035–3046.
    • (2007) J Immunol , vol.179 , pp. 3035-3046
    • Pandrea, I.1    Gautam, R.2    Ribeiro, R.3    Brenchley, J.M.4    Butler, I.F.5
  • 28
    • 84899062375 scopus 로고    scopus 로고
    • Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild
    • Ma D, Jasinska AJ, Feyertag F, Wijewardana V, Kristoff J, et al. (2014) Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild. J Virol 88: 5687–5705. doi: 10.1128/JVI.03606-13 24623416
    • (2014) J Virol , vol.88 , pp. 5687-5705
    • Ma, D.1    Jasinska, A.J.2    Feyertag, F.3    Wijewardana, V.4    Kristoff, J.5
  • 29
    • 84865171842 scopus 로고    scopus 로고
    • Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates
    • Pandrea I, Cornell E, Wilson C, Ribeiro RM, Ma D, et al. (2012) Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates. Blood 120: 1357–1366. doi: 10.1182/blood-2012-03-414706 22653975
    • (2012) Blood , vol.120 , pp. 1357-1366
    • Pandrea, I.1    Cornell, E.2    Wilson, C.3    Ribeiro, R.M.4    Ma, D.5
  • 30
    • 58149177783 scopus 로고    scopus 로고
    • Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion
    • Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, et al. (2008) Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion. J Immunol 181: 6687–6691. 18981083
    • (2008) J Immunol , vol.181 , pp. 6687-6691
    • Pandrea, I.1    Gaufin, T.2    Brenchley, J.M.3    Gautam, R.4    Monjure, C.5
  • 31
    • 77950246404 scopus 로고    scopus 로고
    • Rifaximin treatment in hepatic encephalopathy
    • Bass NM, Mullen KD, Sanyal A, Poordad F, Neff G, et al. (2010) Rifaximin treatment in hepatic encephalopathy. N Engl J Med 362: 1071–1081. doi: 10.1056/NEJMoa0907893 20335583
    • (2010) N Engl J Med , vol.362 , pp. 1071-1081
    • Bass, N.M.1    Mullen, K.D.2    Sanyal, A.3    Poordad, F.4    Neff, G.5
  • 32
    • 0024549269 scopus 로고
    • Sulfasalazine therapy in inflammatory bowel disease
    • Das KM, (1989) Sulfasalazine therapy in inflammatory bowel disease. Gastroenterol Clin North Am 18: 1–20. 2563989
    • (1989) Gastroenterol Clin North Am , vol.18 , pp. 1-20
    • Das, K.M.1
  • 33
    • 0021070329 scopus 로고
    • Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine
    • Das KM, (1983) Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine. Postgrad Med 74: 141–148, 150–141. 6139795
    • (1983) Postgrad Med , vol.74 , pp. 141-148
    • Das, K.M.1
  • 34
    • 44649201289 scopus 로고    scopus 로고
    • HIV infection and the gastrointestinal immune system
    • Brenchley JM, Douek DC, (2008) HIV infection and the gastrointestinal immune system. Mucosal Immunol 1: 23–30. doi: 10.1038/mi.2007.1 19079157
    • (2008) Mucosal Immunol , vol.1 , pp. 23-30
    • Brenchley, J.M.1    Douek, D.C.2
  • 35
    • 77958083540 scopus 로고    scopus 로고
    • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
    • Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, et al. (2010) Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. PLoS Pathog 6: e1001052. doi: 10.1371/journal.ppat.1001052 20808901
    • (2010) PLoS Pathog , vol.6 , pp. 1001052
    • Estes, J.D.1    Harris, L.D.2    Klatt, N.R.3    Tabb, B.4    Pittaluga, S.5
  • 36
    • 55949084601 scopus 로고    scopus 로고
    • Inflammatory and coagulation biomarkers and mortality in patients with HIV infection
    • Kuller LH, Tracy R, Belloso W, De Wit S, Drummond F, et al. (2008) Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med 5: e203. doi: 10.1371/journal.pmed.0050203 18942885
    • (2008) PLoS Med , vol.5 , pp. 203
    • Kuller, L.H.1    Tracy, R.2    Belloso, W.3    De Wit, S.4    Drummond, F.5
  • 37
    • 0032955651 scopus 로고    scopus 로고
    • Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
    • Giorgi JV, Hultin LE, McKeating JA, Johnson TD, Owens B, et al. (1999) Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis 179: 859–870. 10068581
    • (1999) J Infect Dis , vol.179 , pp. 859-870
    • Giorgi, J.V.1    Hultin, L.E.2    McKeating, J.A.3    Johnson, T.D.4    Owens, B.5
  • 38
    • 0036534655 scopus 로고    scopus 로고
    • Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection
    • Giorgi JV, Lyles RH, Matud JL, Yamashita TE, Mellors JW, et al. (2002) Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection. J Acquir Immune Defic Syndr 29: 346–355. 11917238
    • (2002) J Acquir Immune Defic Syndr , vol.29 , pp. 346-355
    • Giorgi, J.V.1    Lyles, R.H.2    Matud, J.L.3    Yamashita, T.E.4    Mellors, J.W.5
  • 39
    • 0041327667 scopus 로고    scopus 로고
    • Persistent immune activation in HIV-1 infection is associated with progression to AIDS
    • Hazenberg MD, Otto SA, van Benthem BH, Roos MT, Coutinho RA, et al. (2003) Persistent immune activation in HIV-1 infection is associated with progression to AIDS. Aids 17: 1881–1888. 12960820
    • (2003) Aids , vol.17 , pp. 1881-1888
    • Hazenberg, M.D.1    Otto, S.A.2    van Benthem, B.H.3    Roos, M.T.4    Coutinho, R.A.5
  • 40
    • 33749079234 scopus 로고    scopus 로고
    • Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection
    • Rodriguez B, Sethi AK, Cheruvu VK, Mackay W, Bosch RJ, et al. (2006) Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. Jama 296: 1498–1506. 17003398
    • (2006) Jama , vol.296 , pp. 1498-1506
    • Rodriguez, B.1    Sethi, A.K.2    Cheruvu, V.K.3    Mackay, W.4    Bosch, R.J.5
  • 41
    • 79952335046 scopus 로고    scopus 로고
    • Plasma levels of soluble CD14 independently predict mortality in HIV infection
    • Sandler NG, Wand H, Roque A, Law M, Nason MC, et al. (2011) Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 203: 780–790. doi: 10.1093/infdis/jiq118 21252259
    • (2011) J Infect Dis , vol.203 , pp. 780-790
    • Sandler, N.G.1    Wand, H.2    Roque, A.3    Law, M.4    Nason, M.C.5
  • 42
    • 75649127335 scopus 로고    scopus 로고
    • Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation
    • Funderburg NT, Mayne E, Sieg SF, Asaad R, Jiang W, et al. (2010) Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood 115: 161–167. doi: 10.1182/blood-2009-03-210179 19828697
    • (2010) Blood , vol.115 , pp. 161-167
    • Funderburg, N.T.1    Mayne, E.2    Sieg, S.F.3    Asaad, R.4    Jiang, W.5
  • 43
    • 84912144937 scopus 로고    scopus 로고
    • Sevelamer does not decrease lipopolysaccharide or soluble CD14 but does decrease soluble tissue factor, LDL, and oxidized LDL levels in untreated HIV infection
    • Sandler NG, Zhang X, Bosch RJ, Funderburg NT, Choi AI, et al. (2014) Sevelamer does not decrease lipopolysaccharide or soluble CD14 but does decrease soluble tissue factor, LDL, and oxidized LDL levels in untreated HIV infection. J Infect Dis: in press.
    • (2014) J Infect Dis
    • Sandler, N.G.1    Zhang, X.2    Bosch, R.J.3    Funderburg, N.T.4    Choi, A.I.5
  • 44
    • 4644342929 scopus 로고    scopus 로고
    • CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    • Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, et al. (2004) CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 200: 749–759. 15365096
    • (2004) J Exp Med , vol.200 , pp. 749-759
    • Brenchley, J.M.1    Schacker, T.W.2    Ruff, L.E.3    Price, D.A.4    Taylor, J.H.5
  • 45
    • 17844376742 scopus 로고    scopus 로고
    • Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
    • Li Q, Duan L, Estes JD, Ma ZM, Rourke T, et al. (2005) Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 434: 1148–1152. 15793562
    • (2005) Nature , vol.434 , pp. 1148-1152
    • Li, Q.1    Duan, L.2    Estes, J.D.3    Ma, Z.M.4    Rourke, T.5
  • 46
    • 17844374605 scopus 로고    scopus 로고
    • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    • Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, et al. (2005) Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 434: 1093–1097. 15793563
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5
  • 47
    • 4644289983 scopus 로고    scopus 로고
    • Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
    • Mehandru S, Poles MA, Tenner-Racz K, Horowitz A, Hurley A, et al. (2004) Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J Exp Med 200: 761–770. 15365095
    • (2004) J Exp Med , vol.200 , pp. 761-770
    • Mehandru, S.1    Poles, M.A.2    Tenner-Racz, K.3    Horowitz, A.4    Hurley, A.5
  • 48
    • 79751498592 scopus 로고    scopus 로고
    • Microbial translocation: a marker of advanced HIV-1 infection and a predictor of treatment failure?
    • Cassol E, Rossouw T, Seebregts C, Cassol S, (2011) Microbial translocation: a marker of advanced HIV-1 infection and a predictor of treatment failure? J Infect Dis 203: 747–748. doi: 10.1093/infdis/jiq109 21278212
    • (2011) J Infect Dis , vol.203 , pp. 747-748
    • Cassol, E.1    Rossouw, T.2    Seebregts, C.3    Cassol, S.4
  • 49
    • 84867805420 scopus 로고    scopus 로고
    • Microbial translocation and infectious diseases: what is the link?
    • D'Ettorre G, Douek D, Paiardini M, Ceccarelli G, Vullo V, (2012) Microbial translocation and infectious diseases: what is the link? Int J Microbiol 2012: 356981. doi: 10.1155/2012/356981 23091494
    • (2012) Int J Microbiol , vol.2012 , pp. 356981
    • D'Ettorre, G.1    Douek, D.2    Paiardini, M.3    Ceccarelli, G.4    Vullo, V.5
  • 50
    • 77955168465 scopus 로고    scopus 로고
    • Microbial translocation in simian immunodeficiency virus (SIV)-infected rhesus monkeys (Macaca mulatta)
    • Leinert C, Stahl-Hennig C, Ecker A, Schneider T, Fuchs D, et al. (2010) Microbial translocation in simian immunodeficiency virus (SIV)-infected rhesus monkeys (Macaca mulatta). J Med Primatol 39: 243–251. doi: 10.1111/j.1600-0684.2010.00429.x 20618590
    • (2010) J Med Primatol , vol.39 , pp. 243-251
    • Leinert, C.1    Stahl-Hennig, C.2    Ecker, A.3    Schneider, T.4    Fuchs, D.5
  • 51
    • 84880207054 scopus 로고    scopus 로고
    • Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004
    • Naranbhai V, Samsunder N, Sandler NG, Roque A, Abdool Karim Q, et al. (2013) Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004. J Acquir Immune Defic Syndr 63: 294–298. doi: 10.1097/QAI.0b013e31828e604b 23481666
    • (2013) J Acquir Immune Defic Syndr , vol.63 , pp. 294-298
    • Naranbhai, V.1    Samsunder, N.2    Sandler, N.G.3    Roque, A.4    Abdool Karim, Q.5
  • 52
    • 79751508059 scopus 로고    scopus 로고
    • Is microbial translocation a cause or consequence of HIV disease progression?
    • Redd AD, Gray RH, Quinn TC, (2011) Is microbial translocation a cause or consequence of HIV disease progression? J Infect Dis 203: 744–745; author reply 746. doi: 10.1093/infdis/jiq107 21220777
    • (2011) J Infect Dis , vol.203 , pp. 744-745
    • Redd, A.D.1    Gray, R.H.2    Quinn, T.C.3
  • 53
    • 84856821605 scopus 로고    scopus 로고
    • Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques
    • Klatt NR, Canary LA, Vanderford TH, Vinton CL, Engram JC, et al. (2012) Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques. J Virol 86: 1203–1213. doi: 10.1128/JVI.06033-11 22090099
    • (2012) J Virol , vol.86 , pp. 1203-1213
    • Klatt, N.R.1    Canary, L.A.2    Vanderford, T.H.3    Vinton, C.L.4    Engram, J.C.5
  • 54
    • 77953739215 scopus 로고    scopus 로고
    • Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection
    • Klatt NR, Harris LD, Vinton CL, Sung H, Briant JA, et al. (2010) Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection. Mucosal Immunol 3: 387–398. doi: 10.1038/mi.2010.14 20357762
    • (2010) Mucosal Immunol , vol.3 , pp. 387-398
    • Klatt, N.R.1    Harris, L.D.2    Vinton, C.L.3    Sung, H.4    Briant, J.A.5
  • 55
    • 0032797799 scopus 로고    scopus 로고
    • Thrombotic microangiopathy in the HIV-2-infected macaque
    • Eitner F, Cui Y, Hudkins KL, Schmidt A, Birkebak T, et al. (1999) Thrombotic microangiopathy in the HIV-2-infected macaque. Am J Pathol 155: 649–661. 10433958
    • (1999) Am J Pathol , vol.155 , pp. 649-661
    • Eitner, F.1    Cui, Y.2    Hudkins, K.L.3    Schmidt, A.4    Birkebak, T.5
  • 56
    • 49349094690 scopus 로고    scopus 로고
    • Rifaximin for the treatment of newly diagnosed Crohn's disease: a case series
    • Shafran I, Burgunder P, (2008) Rifaximin for the treatment of newly diagnosed Crohn's disease: a case series. Am J Gastroenterol 103: 2158–2160. doi: 10.1111/j.1572-0241.2008.01982_16.x 18796124
    • (2008) Am J Gastroenterol , vol.103 , pp. 2158-2160
    • Shafran, I.1    Burgunder, P.2
  • 57
    • 0029548254 scopus 로고    scopus 로고
    • The effect of 5-aminosalicylate and para-aminosalicylate on the synthesis of prostaglandin E2 and leukotriene B4 in isolated colonic mucosal cells
    • Schmidt C, Fels T, Baumeister B, Vetter H, (1996) The effect of 5-aminosalicylate and para-aminosalicylate on the synthesis of prostaglandin E2 and leukotriene B4 in isolated colonic mucosal cells. Curr Med Res Opin 13: 417–425. 8862941
    • (1996) Curr Med Res Opin , vol.13 , pp. 417-425
    • Schmidt, C.1    Fels, T.2    Baumeister, B.3    Vetter, H.4
  • 58
    • 0023405963 scopus 로고
    • Sulfasalazine and new analogues in inflammatory bowel disease, with focus on Crohn's disease
    • van Hees PA, (1987) Sulfasalazine and new analogues in inflammatory bowel disease, with focus on Crohn's disease. Acta Gastroenterol Belg 50: 555–559. 2902723
    • (1987) Acta Gastroenterol Belg , vol.50 , pp. 555-559
    • van Hees, P.A.1
  • 59
    • 84885753789 scopus 로고    scopus 로고
    • Systemic effects of inflammation on health during chronic HIV infection
    • Deeks SG, Tracy R, Douek DC, (2013) Systemic effects of inflammation on health during chronic HIV infection. Immunity 39: 633–645. doi: 10.1016/j.immuni.2013.10.001 24138880
    • (2013) Immunity , vol.39 , pp. 633-645
    • Deeks, S.G.1    Tracy, R.2    Douek, D.C.3
  • 60
    • 84938852381 scopus 로고    scopus 로고
    • Effects of Co-Trimoxazole on Microbial Translocation in HIV-1-Infected Patients Initiating Antiretroviral Therapy
    • Vesterbacka J, Barqasho B, Haggblom A, Nowak P, (2015) Effects of Co-Trimoxazole on Microbial Translocation in HIV-1-Infected Patients Initiating Antiretroviral Therapy. AIDS Res Hum Retroviruses 31: 830–836. doi: 10.1089/AID.2014.0366 26059763
    • (2015) AIDS Res Hum Retroviruses , vol.31 , pp. 830-836
    • Vesterbacka, J.1    Barqasho, B.2    Haggblom, A.3    Nowak, P.4
  • 61
    • 52049117618 scopus 로고    scopus 로고
    • PGJ2 antagonizes NF-kappaB-induced HIV-1 LTR activation in colonic epithelial cells
    • Boisvert M, Cote S, Vargas A, Pasvanis S, Bounou S, et al. (2008) PGJ2 antagonizes NF-kappaB-induced HIV-1 LTR activation in colonic epithelial cells. Virology 380: 1–11. doi: 10.1016/j.virol.2008.07.023 18755491
    • (2008) Virology , vol.380 , pp. 1-11
    • Boisvert, M.1    Cote, S.2    Vargas, A.3    Pasvanis, S.4    Bounou, S.5
  • 62
    • 0036349514 scopus 로고    scopus 로고
    • Prostaglandin E(2) inhibits replication of HIV-1 in macrophages through activation of protein kinase A
    • Hayes MM, Lane BR, King SR, Markovitz DM, Coffey MJ, (2002) Prostaglandin E(2) inhibits replication of HIV-1 in macrophages through activation of protein kinase A. Cell Immunol 215: 61–71. 12142037
    • (2002) Cell Immunol , vol.215 , pp. 61-71
    • Hayes, M.M.1    Lane, B.R.2    King, S.R.3    Markovitz, D.M.4    Coffey, M.J.5
  • 63
    • 80052059246 scopus 로고    scopus 로고
    • An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses
    • Pettersen FO, Torheim EA, Dahm AE, Aaberge IS, Lind A, et al. (2011) An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses. J Virol 85: 6557–6566. doi: 10.1128/JVI.00073-11 21490090
    • (2011) J Virol , vol.85 , pp. 6557-6566
    • Pettersen, F.O.1    Torheim, E.A.2    Dahm, A.E.3    Aaberge, I.S.4    Lind, A.5
  • 64
    • 30844472690 scopus 로고    scopus 로고
    • Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients
    • Rodriguez-Torres M, Rodriguez-Orengo JF, Rios-Bedoya CF, Fernandez-Carbia A, Salgado-Mercado R, et al. (2006) Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients. Dig Dis Sci 51: 161–167. 16416230
    • (2006) Dig Dis Sci , vol.51 , pp. 161-167
    • Rodriguez-Torres, M.1    Rodriguez-Orengo, J.F.2    Rios-Bedoya, C.F.3    Fernandez-Carbia, A.4    Salgado-Mercado, R.5
  • 65
    • 84875670330 scopus 로고    scopus 로고
    • Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy
    • Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, et al. (2013) Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. PLoS One 8: e60042. doi: 10.1371/journal.pone.0060042 23565181
    • (2013) PLoS One , vol.8 , pp. 60042
    • Bajaj, J.S.1    Heuman, D.M.2    Sanyal, A.J.3    Hylemon, P.B.4    Sterling, R.K.5
  • 66
    • 84939509426 scopus 로고    scopus 로고
    • Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy—ACTG A5286
    • Tenorio AR, Chan ES, Bosch RJ, Macatangay BJ, Read SW, et al. (2015) Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy—ACTG A5286. J Infect Dis 211: 780–790. doi: 10.1093/infdis/jiu515 25214516
    • (2015) J Infect Dis , vol.211 , pp. 780-790
    • Tenorio, A.R.1    Chan, E.S.2    Bosch, R.J.3    Macatangay, B.J.4    Read, S.W.5
  • 67
    • 84873369889 scopus 로고    scopus 로고
    • Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques
    • Klatt NR, Canary LA, Sun X, Vinton CL, Funderburg NT, et al. (2013) Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. J Clin Invest 123: 903–907. doi: 10.1172/JCI66227 23321668
    • (2013) J Clin Invest , vol.123 , pp. 903-907
    • Klatt, N.R.1    Canary, L.A.2    Sun, X.3    Vinton, C.L.4    Funderburg, N.T.5
  • 68
    • 84925494695 scopus 로고    scopus 로고
    • Using the pathogenic and nonpathogenic nonhuman primate model for studying non-AIDS comorbidities
    • Pandrea I, Landay A, Wilson C, Stock J, Tracy R, et al. (2015) Using the pathogenic and nonpathogenic nonhuman primate model for studying non-AIDS comorbidities. Curr HIV/AIDS Rep 12: 54–67. doi: 10.1007/s11904-014-0245-5 25604236
    • (2015) Curr HIV/AIDS Rep , vol.12 , pp. 54-67
    • Pandrea, I.1    Landay, A.2    Wilson, C.3    Stock, J.4    Tracy, R.5
  • 69
    • 84901933676 scopus 로고    scopus 로고
    • Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
    • Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, et al. (2014) Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature 511: 601–605. doi: 10.1038/nature13554 25043006
    • (2014) Nature , vol.511 , pp. 601-605
    • Sandler, N.G.1    Bosinger, S.E.2    Estes, J.D.3    Zhu, R.T.4    Tharp, G.K.5
  • 71
    • 80052314332 scopus 로고    scopus 로고
    • Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion
    • Pandrea I, Gaufin T, Gautam R, Kristoff J, Mandell D, et al. (2011) Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion. PLoS Pathog 7: e1002170. doi: 10.1371/journal.ppat.1002170 21829366
    • (2011) PLoS Pathog , vol.7 , pp. 1002170
    • Pandrea, I.1    Gaufin, T.2    Gautam, R.3    Kristoff, J.4    Mandell, D.5
  • 72
    • 20944439417 scopus 로고    scopus 로고
    • Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys
    • Pandrea I, Kornfeld C, Ploquin MJ, Apetrei C, Faye A, et al. (2005) Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys. J Virol 79: 6249–6259. 15858009
    • (2005) J Virol , vol.79 , pp. 6249-6259
    • Pandrea, I.1    Kornfeld, C.2    Ploquin, M.J.3    Apetrei, C.4    Faye, A.5
  • 73
    • 41149146472 scopus 로고    scopus 로고
    • Simian immunodeficiency virus SIVagm dynamics in African green monkeys
    • Pandrea I, Ribeiro RM, Gautam R, Gaufin T, Pattison M, et al. (2008) Simian immunodeficiency virus SIVagm dynamics in African green monkeys. J Virol 82: 3713–3724. doi: 10.1128/JVI.02402-07 18216122
    • (2008) J Virol , vol.82 , pp. 3713-3724
    • Pandrea, I.1    Ribeiro, R.M.2    Gautam, R.3    Gaufin, T.4    Pattison, M.5
  • 74
    • 33646446732 scopus 로고    scopus 로고
    • Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts
    • Pandrea I, Apetrei C, Dufour J, Dillon N, Barbercheck J, et al. (2006) Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts. J Virol 80: 4858–4867. 16641277
    • (2006) J Virol , vol.80 , pp. 4858-4867
    • Pandrea, I.1    Apetrei, C.2    Dufour, J.3    Dillon, N.4    Barbercheck, J.5
  • 75
    • 67749095197 scopus 로고    scopus 로고
    • Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo
    • Gautam R, Gaufin T, Butler I, Gautam A, Barnes M, et al. (2009) Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo. J Virol 83: 7894–7908. doi: 10.1128/JVI.00444-09 19493994
    • (2009) J Virol , vol.83 , pp. 7894-7908
    • Gautam, R.1    Gaufin, T.2    Butler, I.3    Gautam, A.4    Barnes, M.5
  • 76
    • 0141819106 scopus 로고    scopus 로고
    • Tissue factor, thrombin, and cancer
    • Rickles FR, Patierno S, Fernandez PM, (2003) Tissue factor, thrombin, and cancer. Chest 124: 58S–68S. 12970125
    • (2003) Chest , vol.124 , pp. 58-68
    • Rickles, F.R.1    Patierno, S.2    Fernandez, P.M.3
  • 78
    • 84982157002 scopus 로고    scopus 로고
    • Alterations in intestinal microbiota correlate with susceptibility to type 1 diabetes
    • Alkanani AK, Hara N, Gottlieb PA, Ir D, Robertson CE, et al. (2015) Alterations in intestinal microbiota correlate with susceptibility to type 1 diabetes. Diabetes.
    • (2015) Diabetes
    • Alkanani, A.K.1    Hara, N.2    Gottlieb, P.A.3    Ir, D.4    Robertson, C.E.5
  • 79
    • 84900493012 scopus 로고    scopus 로고
    • An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia
    • Dillon SM, Lee EJ, Kotter CV, Austin GL, Dong Z, et al. (2014) An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. Mucosal Immunol 7: 983–994. doi: 10.1038/mi.2013.116 24399150
    • (2014) Mucosal Immunol , vol.7 , pp. 983-994
    • Dillon, S.M.1    Lee, E.J.2    Kotter, C.V.3    Austin, G.L.4    Dong, Z.5
  • 80
    • 84920952610 scopus 로고    scopus 로고
    • Microbiome manipulation modifies sex-specific risk for autoimmunity
    • Markle JG, Frank DN, Adeli K, von Bergen M, Danska JS, (2014) Microbiome manipulation modifies sex-specific risk for autoimmunity. Gut Microbes 5: 485–493. doi: 10.4161/gmic.29795 25007153
    • (2014) Gut Microbes , vol.5 , pp. 485-493
    • Markle, J.G.1    Frank, D.N.2    Adeli, K.3    von Bergen, M.4    Danska, J.S.5
  • 81
    • 42349100152 scopus 로고    scopus 로고
    • Critical evaluation of two primers commonly used for amplification of bacterial 16S rRNA genes
    • Frank JA, Reich CI, Sharma S, Weisbaum JS, Wilson BA, et al. (2008) Critical evaluation of two primers commonly used for amplification of bacterial 16S rRNA genes. Appl Environ Microbiol 74: 2461–2470. doi: 10.1128/AEM.02272-07 18296538
    • (2008) Appl Environ Microbiol , vol.74 , pp. 2461-2470
    • Frank, J.A.1    Reich, C.I.2    Sharma, S.3    Weisbaum, J.S.4    Wilson, B.A.5
  • 82
    • 0024226575 scopus 로고
    • Reverse transcriptase sequencing of ribosomal RNA for phylogenetic analysis
    • Lane DJ, Field KG, Olsen GJ, Pace NR, (1988) Reverse transcriptase sequencing of ribosomal RNA for phylogenetic analysis. Methods Enzymol 167: 138–144. 2467178
    • (1988) Methods Enzymol , vol.167 , pp. 138-144
    • Lane, D.J.1    Field, K.G.2    Olsen, G.J.3    Pace, N.R.4
  • 83
    • 84864134721 scopus 로고    scopus 로고
    • SINA: accurate high-throughput multiple sequence alignment of ribosomal RNA genes
    • Pruesse E, Peplies J, Glockner FO, (2012) SINA: accurate high-throughput multiple sequence alignment of ribosomal RNA genes. Bioinformatics 28: 1823–1829. doi: 10.1093/bioinformatics/bts252 22556368
    • (2012) Bioinformatics , vol.28 , pp. 1823-1829
    • Pruesse, E.1    Peplies, J.2    Glockner, F.O.3
  • 84
    • 84873739311 scopus 로고    scopus 로고
    • The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
    • Quast C, Pruesse E, Yilmaz P, Gerken J, Schweer T, et al. (2013) The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res 41: D590–596. doi: 10.1093/nar/gks1219 23193283
    • (2013) Nucleic Acids Res , vol.41 , pp. 590-596
    • Quast, C.1    Pruesse, E.2    Yilmaz, P.3    Gerken, J.4    Schweer, T.5
  • 85
    • 84890041312 scopus 로고    scopus 로고
    • Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data
    • Robertson CE, Harris JK, Wagner BD, Granger D, Browne K, et al. (2013) Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data. Bioinformatics 29: 3100–3101. doi: 10.1093/bioinformatics/btt526 24021386
    • (2013) Bioinformatics , vol.29 , pp. 3100-3101
    • Robertson, C.E.1    Harris, J.K.2    Wagner, B.D.3    Granger, D.4    Browne, K.5
  • 86
    • 84969430092 scopus 로고    scopus 로고
    • Oksanen J (2008) Vegan: Community ecology package. R package version 115–1 http://veganr-forger-projectorg.
  • 87
    • 0036146824 scopus 로고    scopus 로고
    • Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set
    • Nadkarni MA, Martin FE, Jacques NA, Hunter N, (2002) Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set. Microbiology 148: 257–266. 11782518
    • (2002) Microbiology , vol.148 , pp. 257-266
    • Nadkarni, M.A.1    Martin, F.E.2    Jacques, N.A.3    Hunter, N.4
  • 88
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank DN, Amand AL, StFeldman RA, Boedeker EC, Harpaz N, et al. (2007) Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 104: 13780–13785. 17699621
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13780-13785
    • Frank, D.N.1    Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.